InAADR

Drug Information

Drug Name: Isosorbide Dinitrate (87-33-2)
PubChem ID: 6883
SMILES: C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O[N+](=O)[O-])O[N+](=O)[O-]
InchiKey: MOYKHGMNXAOIAT-JGWLITMVSA-N
Therapeutic Category: Cardiovascular Agents, Nitric Oxide Donors, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 236.136
LogP: -1.0622
Ring Count: 0
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 123.2

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Laboratory Findings MetaADEDB
Abnormal Vision MetaADEDB
Accidental Exposure MetaADEDB
Acidosis MetaADEDB
Actinic Keratosis MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Failure MetaADEDB
Administration Site Pain MetaADEDB
Afib MetaADEDB
Alanine Aminotransferase MetaADEDB
Alcoholism MetaADEDB
Anaemia MetaADEDB
Anemia Hemolytic MetaADEDB
Angina MetaADEDB
Angina Pectoris SIDER
Angina Unstable ADReCS
Anorexia MetaADEDB
Anterograde Amnesia MetaADEDB
Anti-Insulin Antibody MetaADEDB
Anuria MetaADEDB
Aortic Aneurysm MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Application Site Reaction MetaADEDB
Arterial Bypass Operation MetaADEDB
Arterial Haemorrhage MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis Obliterans MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriovenous Fistula Operation MetaADEDB
Arteriovenous Graft Thrombosis MetaADEDB
Aspartate Aminotransferase Decreased MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia MetaADEDB
Asystole MetaADEDB
Atrioventricular Block MetaADEDB
Autonomic Instability MetaADEDB
Bacteraemia MetaADEDB
Benign Mesothelioma MetaADEDB
Black Stools MetaADEDB
Bleb MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Amylase Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Cholesterol Decreased MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Insulin MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Platelet Disorders MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Abnormal ADReCS
Blood Sodium MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Blood Urea Decreased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Bone Pain MetaADEDB
Bradycardia MetaADEDB
Bradypnoea MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Breast Cyst MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level Above Therapeutic MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Insufficiency MetaADEDB
Carotid Artery Stenosis MetaADEDB
Carotid Endarterectomy MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Chest Pain MetaADEDB
Chill MetaADEDB
Choking MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Clostridial Infection MetaADEDB
Cluster Headache MetaADEDB
Cold Sweat MetaADEDB
Colitis Pseudomembranous MetaADEDB
Coma MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Corneal Disorder MetaADEDB
Coronary Artery Disease MetaADEDB
Coronary Artery Occlusion MetaADEDB
Coronary Disease MetaADEDB
Coronary Stenosis MetaADEDB
Coronary Vasospasm MetaADEDB
Cough MetaADEDB
Crackles Lung MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Decubitus Ulcer MetaADEDB
Dehydration MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressed Mood MetaADEDB
Dermatitides MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diastolic Dysfunction MetaADEDB
Difficulty In Walking MetaADEDB
Disease Of Liver MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dissociative Disorder MetaADEDB
Diverticulitis MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Duodenal Ulcer MetaADEDB
Dysgeusia MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Electrocardiogram Pq Interval Prolonged MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electromechanical Dissociation MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Embolism Pulmonary MetaADEDB
Emesis MetaADEDB
Eruption MetaADEDB
Erythema Migrans MetaADEDB
Esophageal And Gastric Varices MetaADEDB
Esophageal Stenosis MetaADEDB
Excess Potassium MetaADEDB
Exercise Tolerance Decreased MetaADEDB
Eyelid Retraction MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue MetaADEDB
Feeling Abnormal MetaADEDB
Fibrin D Dimer MetaADEDB
Fissure In Ano MetaADEDB
Flank Pain MetaADEDB
Fluid Overload MetaADEDB
Foaming At Mouth MetaADEDB
Gamma-Glutamyltransferase MetaADEDB
Gastric Mucosal Lesion MetaADEDB
Gastroenteritis Viral MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Stromal Tumour MetaADEDB
Glossoptosis MetaADEDB
Glycopeptide Antibiotic Resistant Enterococcal Infection MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Groin Infection MetaADEDB
Haemangioma MetaADEDB
Haematemesis MetaADEDB
Haemodialysis MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Hallucinations MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Failure MetaADEDB
Hemifacial Spasm MetaADEDB
Hepatic Atrophy MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis Acute MetaADEDB
Hepatitis Fulminant MetaADEDB
Humerus Fracture MetaADEDB
Hyperkalemia MetaADEDB
Hypertension ADReCS
Hypoaesthesia MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypovolaemic Shock MetaADEDB
Hypoxia MetaADEDB
Iliac Vein Occlusion MetaADEDB
Incontinence MetaADEDB
Incorrect Drug Administration Duration MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infected Lymphocele MetaADEDB
Infection Urinary Tract MetaADEDB
Influenza Like Illness MetaADEDB
Injection Site Discolouration MetaADEDB
Intermittent Claudication MetaADEDB
International Normalised Ratio Increased MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Ischemia MetaADEDB
Joint Instability MetaADEDB
Laryngeal Ulceration MetaADEDB
Leg Amputation MetaADEDB
Leishmaniasis Visceral MetaADEDB
Lethargy MetaADEDB
Lightheadedness SIDER
Limb Operation MetaADEDB
Lip Erosion MetaADEDB
Lipase MetaADEDB
Loss Of Consciousness SIDER
Lung Edema MetaADEDB
Lung Infection Pseudomonal MetaADEDB
Lyell MetaADEDB
Lymphangioma MetaADEDB
Lymphorrhoea MetaADEDB
Mental Status Changes MetaADEDB
Mesenteric Occlusion MetaADEDB
Metabolic Function Test MetaADEDB
Metastases To Spine MetaADEDB
Methaemoglobinaemia ADReCS
Migraine Disorders MetaADEDB
Mitral Valve Calcification MetaADEDB
Mitral Valve Replacement MetaADEDB
Mouth Breathing MetaADEDB
Mouth Ulcer MetaADEDB
Movement Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Myocardial Infarction MetaADEDB
Myocardial Ischemia MetaADEDB
Nasal Sinus Congestion MetaADEDB
Nasopharyngitis MetaADEDB
Nausea MetaADEDB
Near Syncope MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Neumonia MetaADEDB
Neutrophil Count Decreased MetaADEDB
Oliguria MetaADEDB
Oral Mucosa Erosion MetaADEDB
Ovarian Cyst MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain MetaADEDB
Pancreatic Necrosis MetaADEDB
Pancreatitis Chronic MetaADEDB
Paraplegia MetaADEDB
Paresis MetaADEDB
Pedal Pulse Absent MetaADEDB
Pelvic Fluid Collection MetaADEDB
Performance Status Decreased MetaADEDB
Pericardial Effusion MetaADEDB
Peripheral Revascularisation MetaADEDB
Petechia MetaADEDB
Pharyngeal Disorder MetaADEDB
Pituitary Apoplexy MetaADEDB
Plasma Cell Count MetaADEDB
Platelet Count MetaADEDB
Platelet Count Abnormal MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumonia Necrotising MetaADEDB
Pre-Eclampsia MetaADEDB
Prostate Cancer Metastatic MetaADEDB
Protein Total Increased MetaADEDB
Psoriasis MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Embolism MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulse Abnormal MetaADEDB
Rales MetaADEDB
Rebound Hypertension SIDER
Red Blood Cell Sedimentation Rate MetaADEDB
Renal Atrophy MetaADEDB
Renal Cyst MetaADEDB
Renal Impairment MetaADEDB
Renal Insufficiency MetaADEDB
Renal Tubular Necrosis MetaADEDB
Reperfusion Injury MetaADEDB
Respiratory Failure MetaADEDB
Retrograde Amnesia MetaADEDB
Serum Sickness MetaADEDB
Shock SIDER
Skin Tightness MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sudden Cardiac Death MetaADEDB
Swollen Tongue MetaADEDB
Syncope ADReCS
Synovial Fluid Red Blood Cells Positive MetaADEDB
Tachycardia MetaADEDB
Thrombectomy MetaADEDB
Thrombosis In Device MetaADEDB
Toe Amputation MetaADEDB
Transplant Failure MetaADEDB
Troponin I Increased MetaADEDB
Urticaria MetaADEDB
Vascular Dementia MetaADEDB
Vascular Graft MetaADEDB
Vascular Pseudoaneurysm MetaADEDB
Vasodilatation ADReCS
Vasoplegia Syndrome MetaADEDB
Ventricular Dysfunction Left MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertebral Artery Stenosis MetaADEDB
Volume Blood Decreased MetaADEDB
Withdrawal Hypertension SIDER
Withdrawal Syndrome MetaADEDB
Wound Infection Pseudomonas MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB

InAADR: Drug-Protein-ADRs database