InAADR

Drug Information

Drug Name: Isoflurane (26675-46-7)
PubChem ID: 3763
SMILES: C(C(F)(F)F)(OC(F)F)Cl
InchiKey: PIWKPBJCKXDKJR-UHFFFAOYSA-N
Therapeutic Category: Anesthetics, Central Nervous System Agents, Central Nervous System Depressants

Computed Drug Properties

Molecular Weight (dalton): 184.491
LogP: 2.3528
Ring Count: 0
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 9.23

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Doxorubicin (23214-92-8) Pr Prolongation Antagonistic Uncertain Is prolongation of the QTc interval during isoflurane anaesthesia more prominent in women pretreated with anthracyclines for breast cancer?

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abuse MetaADEDB
Acidosis MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Psychosis MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenoma MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Agraphia MetaADEDB
Air Embolism MetaADEDB
Akinesia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Amnesia MetaADEDB
Anaemia Of Pregnancy MetaADEDB
Anaesthetic Complication MetaADEDB
Anaesthetic Complication Neurological MetaADEDB
Angle Closure Glaucoma MetaADEDB
Anisocoria MetaADEDB
Anoxia MetaADEDB
Antibiotic Level Above Therapeutic MetaADEDB
Antipsychotic Drug Level Above Therapeutic MetaADEDB
Antipsychotic Drug Level Increased MetaADEDB
Antiviral Drug Level Above Therapeutic MetaADEDB
Apallic Syndrome MetaADEDB
Apnea MetaADEDB
Areflexia MetaADEDB
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriospasm Coronary MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Ataxia MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Tachycardia MetaADEDB
Atrial Thrombosis MetaADEDB
Av Dissociation MetaADEDB
Becker Muscular Dystrophy MetaADEDB
Black Stools MetaADEDB
Blepharospasm MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Body Temperature MetaADEDB
Bradycardia MetaADEDB
Brain Diseases MetaADEDB
Brain Injuries MetaADEDB
Brain Ischemia MetaADEDB
Breakthrough Bleeding MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bulbar Palsy MetaADEDB
Caesarean Section MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Aneurysm MetaADEDB
Cardiac Arrest ADReCS
Cardiac Decompensation MetaADEDB
Cardiac Disorder ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Procedure Complication MetaADEDB
Cardiomyopathies MetaADEDB
Cardiovascular Diseases MetaADEDB
Catheter Related Complication MetaADEDB
Catheter Site Haemorrhage MetaADEDB
Causalgia MetaADEDB
Central Venous Pressure Increased MetaADEDB
Cerebral Ischaemia MetaADEDB
Cervicalgia MetaADEDB
Chest Wall Pain MetaADEDB
Chills ADReCS
Cholangiolitis MetaADEDB
Cholestasis MetaADEDB
Clonus MetaADEDB
Clotting MetaADEDB
Coagulation Test Abnormal MetaADEDB
Cognition Disorders MetaADEDB
Coma MetaADEDB
Confabulation MetaADEDB
Confusion MetaADEDB
Congenital Pulmonary Hypertension MetaADEDB
Congenital Urinary Tract Obstruction MetaADEDB
Conversion Disorder MetaADEDB
Coordination Abnormal MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coronary Disease MetaADEDB
Cough ADReCS
Critical Illness Polyneuropathy MetaADEDB
Deafness Neurosensory MetaADEDB
Death Sudden MetaADEDB
Decubitus Ulcer MetaADEDB
Delayed Recovery From Anaesthesia MetaADEDB
Delirium ADReCS
Delusion MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dissociative Disorder MetaADEDB
Dizziness MetaADEDB
Drowsiness MetaADEDB
Drug Effect Prolonged MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Drug Interaction Potentiation MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dysphasia MetaADEDB
Dystonia MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Electrocardiogram St-T Change MetaADEDB
Electromechanical Dissociation MetaADEDB
Embolism Venous MetaADEDB
Endocarditis MetaADEDB
Enterobacter Pneumonia MetaADEDB
Eosinophilia MetaADEDB
Epidural Hematoma MetaADEDB
Erosive Gastritis MetaADEDB
Excess Potassium MetaADEDB
Excitement SIDER
Familial Risk Factor MetaADEDB
Fasciculation MetaADEDB
Fever MetaADEDB
Fibrous Histiocytoma MetaADEDB
Foetal Malpresentation MetaADEDB
Gangrene MetaADEDB
Gaze Palsy MetaADEDB
Genital Erosion MetaADEDB
Glasgow Coma Scale MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Haematoma Evacuation MetaADEDB
Haemodialysis MetaADEDB
Haemodilution MetaADEDB
Haemodynamic Instability MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache MetaADEDB
Heart Arrest MetaADEDB
Heart Failure MetaADEDB
Heart Rate Increased MetaADEDB
Hemiparesis MetaADEDB
Hemiplegia MetaADEDB
Hemiplegia Transient MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Necrosis ADReCS
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Hepatobiliary Disease SIDER
Hepatocellular Injury MetaADEDB
Hepatomegaly MetaADEDB
Hepatotoxicity MetaADEDB
Hiccups ADReCS
Horner Syndrome MetaADEDB
Hydronephrosis MetaADEDB
Hyperalgesia MetaADEDB
Hyperemia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis MetaADEDB
Hyperkalaemia ADReCS
Hyperphosphataemia MetaADEDB
Hyperreflexia MetaADEDB
Hypertension MetaADEDB
Hyperthermia ADReCS
Hyperthermia Malignant ADReCS
Hypertonia MetaADEDB
Hyperventilation MetaADEDB
Hypocoagulable State MetaADEDB
Hypokalaemia MetaADEDB
Hypotension ADReCS
Hypotonia MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Ileus ADReCS
Incisional Hernia Obstructive MetaADEDB
Incorrect Route Of Drug Administration MetaADEDB
Increased Bronchial Secretion MetaADEDB
Infantile Apnoeic Attack MetaADEDB
Inflammation MetaADEDB
Intentional Drug Misuse MetaADEDB
Intracardiac Thrombus MetaADEDB
Ischaemic Stroke MetaADEDB
Jaundice ADReCS
Kidney Diseases MetaADEDB
Lacrimation Increased MetaADEDB
Laryngospasm ADReCS
Learning Disorders MetaADEDB
Left Atrial Dilatation MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leukoencephalopathy MetaADEDB
Lip Disorder MetaADEDB
Liver Diseases MetaADEDB
Liver Failure Acute MetaADEDB
Liver Neoplasms MetaADEDB
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Malignant Hyperthermia MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mean Arterial Pressure Increased MetaADEDB
Memory Disorders MetaADEDB
Metatarsalgia MetaADEDB
Migraine With Aura MetaADEDB
Miosis MetaADEDB
Mitral Valve Insufficiency MetaADEDB
Movement Disorder MetaADEDB
Mucosal Erosion MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Rigidity ADReCS
Muscle Spasticity MetaADEDB
Mycobacterium Avium Complex Infection SIDER
Mycobacterium Test SIDER
Myocardial Ischemia MetaADEDB
Myotonia MetaADEDB
Nausea ADReCS
Necrosis ADReCS
Nephrogenic Anaemia MetaADEDB
Nerve Degeneration MetaADEDB
Neurobehavioral Manifestations MetaADEDB
Neurodegenerative Diseases MetaADEDB
No Therapeutic Response MetaADEDB
Nuclear Magnetic Resonance Imaging Brain Abnormal MetaADEDB
Oculogyric Crisis MetaADEDB
Oligohydramnios MetaADEDB
Oliguria MetaADEDB
Operative Haemorrhage MetaADEDB
Ovarian Cyst MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain MetaADEDB
Pco2 Decreased MetaADEDB
Peritoneal Dialysis MetaADEDB
Peritonitis MetaADEDB
Phaeochromocytoma MetaADEDB
Phlebothrombosis MetaADEDB
Pneumonia Klebsiella MetaADEDB
Po2 MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Nausea MetaADEDB
Post Procedural Vomiting MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Premature Baby MetaADEDB
Premature Labour MetaADEDB
Premature Rupture Of Membranes MetaADEDB
Procedural Complication MetaADEDB
Procedural Hypotension MetaADEDB
Pseudocholinesterase Deficiency MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Artery Thrombosis MetaADEDB
Pulmonary Edema MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Hypertension MetaADEDB
Pulmonary Valve Insufficiency MetaADEDB
Refusal Of Treatment By Relative MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Depression ADReCS
Respiratory Insufficiency MetaADEDB
Respiratory Rate Increased MetaADEDB
Retained Placenta Or Membranes MetaADEDB
Rhabdomyolysis MetaADEDB
Right Heart Failure MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Seizures MetaADEDB
Sensation Of Heaviness MetaADEDB
Sepsis MetaADEDB
Sepsis Syndrome MetaADEDB
Shivering ADReCS
Shock Haemorrhagic MetaADEDB
Sinus Bradycardia MetaADEDB
Sinus Rhythm MetaADEDB
Somatoform Disorder MetaADEDB
Status Asthmaticus MetaADEDB
Status Epilepticus MetaADEDB
Stridor MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Syncope Vasovagal MetaADEDB
Systemic Candida MetaADEDB
Tachycardia MetaADEDB
Tachycardia Ventricular MetaADEDB
Tetany MetaADEDB
Torsades De Pointes MetaADEDB
Transverse Presentation MetaADEDB
Trismus MetaADEDB
Troponin Increased MetaADEDB
Tumour Lysis Syndrome MetaADEDB
Twin Pregnancy MetaADEDB
Uremia MetaADEDB
Urinary Tract Injury MetaADEDB
Urination Disorders MetaADEDB
Urinoma MetaADEDB
Uterine Atony MetaADEDB
Uterine Bleeding MetaADEDB
Uterine Inversion MetaADEDB
Vascular Bypass Graft MetaADEDB
Vascular Resistance Systemic Decreased MetaADEDB
Vena Cava Thrombosis MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vomiting ADReCS
White Blood Cell Count Increased ADReCS
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database