InAADR

Drug Information

Drug Name: Irbesartan (138402-11-6)
PubChem ID: 3749
SMILES: CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
InchiKey: YOSHYTLCDANDAN-UHFFFAOYSA-N
Therapeutic Category: Angiotensin II Type 1 Receptor Blockers, Angiotensin Receptor Antagonists, Antihypertensive Agents, Cardiovascular Agents

Computed Drug Properties

Molecular Weight (dalton): 428.54
LogP: 4.7774
Ring Count: 3
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 87.13

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension ADReCS
Abdominal Infection MetaADEDB
Abdominal Pain ADReCS
Abnormal Movements MetaADEDB
Ache SIDER
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Adh Inappropriate MetaADEDB
Agitation ADReCS
Agitation Postoperative MetaADEDB
Air Embolism MetaADEDB
Amentia MetaADEDB
Anaemia ADReCS
Anaemia Postoperative MetaADEDB
Anal Haemorrhage MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy MetaADEDB
Angioplasty MetaADEDB
Anhedonia MetaADEDB
Anhidrosis MetaADEDB
Animal Bite MetaADEDB
Anosmia MetaADEDB
Anoxia MetaADEDB
Antidepressant Drug Level Above Therapeutic MetaADEDB
Antipsychotic Drug Level Increased MetaADEDB
Anxiety ADReCS
Aortic Aneurysm MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Valve Calcification MetaADEDB
Aortic Valve Disease MetaADEDB
Application Site Bleeding MetaADEDB
Application Site Discomfort MetaADEDB
Application Site Urticaria MetaADEDB
Arrhythmia ADReCS
Arterial Bruit MetaADEDB
Arterial Disorder MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stent Insertion MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteritis MetaADEDB
Arthralgia PROTECT
Arthritis ADReCS
Asthenia ADReCS
Atrial Hypertrophy MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Back Ache MetaADEDB
Basal Ganglia Haemorrhage MetaADEDB
Bladder Retention MetaADEDB
Blepharitis MetaADEDB
Blindness ADReCS
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Glucose Decreased MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Pressure Immeasurable MetaADEDB
Blood Pressure Orthostatic MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Decreased PROTECT
Blood Test Abnormal MetaADEDB
Blood Urea Increased ADReCS
Body Temperature MetaADEDB
Body Temperature Increased ADReCS
Bone Debridement MetaADEDB
Bone Density Decreased MetaADEDB
Bone Pain MetaADEDB
Bradycardia MetaADEDB
Breast Cancer Metastatic MetaADEDB
Bundle Branch Block Right MetaADEDB
Burning Sensation Mucosal MetaADEDB
Bursitis ADReCS
Calculus Urethral MetaADEDB
Carbohydrate Metabolism Disorder MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Arrest ADReCS
Cardiac Failure ADReCS
Cardiac Ischemia MetaADEDB
Cardiac Murmur ADReCS
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest ADReCS
Cardiogenic Shock MetaADEDB
Cardiovascular Disorder MetaADEDB
Carotid Artery Stenosis MetaADEDB
Carotid Bruit MetaADEDB
Cartilage Development Disorder MetaADEDB
Cellulitis MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Cerebral Artery Occlusion MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Ischaemia MetaADEDB
Cerebrovascular Accident ADReCS
Cervicobrachial Syndrome MetaADEDB
Cervix Haematoma Uterine MetaADEDB
Chest Pain ADReCS
Chills ADReCS
Choking MetaADEDB
Choking Sensation MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Respiratory Failure MetaADEDB
Clavicle Fracture MetaADEDB
Colonic Polyp MetaADEDB
Coma MetaADEDB
Conduction Disorder ADReCS
Confusion Postoperative MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Conjunctivitis ADReCS
Constipated MetaADEDB
Constipation ADReCS
Coronary Artery Stenosis MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Creatine Phosphokinase Increased SIDER
Cutaneous Lupus Erythematosus PROTECT
Deafness Neurosensory MetaADEDB
Dehydration MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Dermographism MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Foot MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Disorder Retinal MetaADEDB
Distention SIDER
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Dizziness Postural ADReCS
Drug Administration Error MetaADEDB
Dry Cough MetaADEDB
Dysgeusia ADReCS
Dysgraphia MetaADEDB
Dyslipidaemia MetaADEDB
Dyspepsia ADReCS
Dysphonia MetaADEDB
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysuria MetaADEDB
Ear Disorder ADReCS
Ear Infection ADReCS
Ear Pain ADReCS
Ecchymoses MetaADEDB
Ecchymosis ADReCS
Electrocardiogram Qt Prolonged MetaADEDB
Electrolyte Imbalance ADReCS
Emesis MetaADEDB
Emotional Disorder ADReCS
Emotional Distress MetaADEDB
Emotional Disturbance Nos SIDER
Epistaxis ADReCS
Erysipelas MetaADEDB
Erythema ADReCS
Erythema Facial ADReCS
Essential Hypertension MetaADEDB
Essential Thrombocythaemia MetaADEDB
Excess Potassium MetaADEDB
Excessive Salivation MetaADEDB
External Ear Infection MetaADEDB
Eyelid Disorder ADReCS
Face Oedema ADReCS
Fatigue ADReCS
Fear Of Eating MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Cold MetaADEDB
Femur Fracture MetaADEDB
Fibrin D Dimer MetaADEDB
Flank Pain MetaADEDB
Flatulence ADReCS
Flushing ADReCS
Foaming At Mouth MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Ulcer MetaADEDB
Gastroenteritis ADReCS
Gastroenteritis Salmonella MetaADEDB
Gastrointestinal Pain ADReCS
General Symptom MetaADEDB
Gout ADReCS
Granulocytosis MetaADEDB
Haematemesis MetaADEDB
Haematochezia MetaADEDB
Haematoma MetaADEDB
Haemoconcentration MetaADEDB
Haemodynamic Instability MetaADEDB
Haemoglobin Decreased ADReCS
Haemoglobin Increased MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhoids MetaADEDB
Hand Deformity MetaADEDB
Headache ADReCS
Hearing Test Abnormal ADReCS
Heart Attack MetaADEDB
Heart Rate Abnormal MetaADEDB
Heartburn ADReCS
Hematoma Subdural MetaADEDB
Hemiparesis MetaADEDB
Hepatic Function Abnormal PROTECT
Hepatitis ADReCS
Hepatocellular Injury MetaADEDB
Hernia MetaADEDB
Herpes Zoster MetaADEDB
Herpes Zoster Ophthalmic MetaADEDB
High Blood Pressure MetaADEDB
Humerus Fracture MetaADEDB
Hydrocephalus MetaADEDB
Hyperammonaemia MetaADEDB
Hyperchloraemia MetaADEDB
Hyperhidrosis MetaADEDB
Hyperkalaemia ADReCS
Hyperkinesia ADReCS
Hypersensitivity PROTECT
Hypersensitivity Vasculitis PROTECT
Hypertension ADReCS
Hypertensive Crisis ADReCS
Hypoaesthesia ADReCS
Hypotension ADReCS
Hypovolaemic Shock MetaADEDB
Infarction ADReCS
Infection ADReCS
Infectious Mononucleosis MetaADEDB
Influenza ADReCS
Intention Tremor MetaADEDB
Internal Injury MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Congestion ADReCS
Ischaemia MetaADEDB
Ischaemic Cerebral Infarction MetaADEDB
Jaundice ADReCS
Joint Abscess MetaADEDB
Joint Stiffness ADReCS
Kidney Failure MetaADEDB
Kidney Pain MetaADEDB
Lacunar Infarction MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Leukoplakia MetaADEDB
Libido Disorder ADReCS
Lip Discolouration MetaADEDB
Livedo Reticularis MetaADEDB
Liver Function Test Abnormal ADReCS
Localised Infection MetaADEDB
Loss Of Consciousness ADReCS
Lower Gastrointestinal Haemorrhage MetaADEDB
Lung Cancer Metastatic MetaADEDB
Lymphopenia ADReCS
Mastication Disorder MetaADEDB
Meningioma MetaADEDB
Meniscus Lesion MetaADEDB
Metastases To Liver MetaADEDB
Micturition Disorder ADReCS
Micturition Urgency MetaADEDB
Middle Ear Inflammation MetaADEDB
Migraine MetaADEDB
Monoplegia MetaADEDB
Mountain Sickness Acute MetaADEDB
Mouth Bleeding MetaADEDB
Mouth Pain MetaADEDB
Mpd MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Musculoskeletal Chest Pain ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Mycobacterium Tuberculosis Infection MetaADEDB
Myocardial Infarction ADReCS
Myopia PROTECT
Myositis ADReCS
Nasal Polyp MetaADEDB
Nasal Septum Deviation MetaADEDB
Nasal Turbinate Hypertrophy MetaADEDB
Nausea ADReCS
Neovascularisation MetaADEDB
Nephrectomy MetaADEDB
Nervousness ADReCS
Neutropenia ADReCS
Neutropenic Colitis MetaADEDB
Neutrophilia MetaADEDB
Nosocomial Infection MetaADEDB
Numbness SIDER
Obstruction Gastric MetaADEDB
Occult Blood Positive MetaADEDB
Oedema ADReCS
Oedema Extremities ADReCS
Oedema Peripheral ADReCS
Oedema Upper Extremities ADReCS
Oliguria MetaADEDB
Oral Disorder ADReCS
Oral Lesion SIDER
Orthostatic Dizziness ADReCS
Orthostatic Hypotension ADReCS
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain Pelvic MetaADEDB
Panniculitis MetaADEDB
Paraesthesia ADReCS
Paraesthesia Oral MetaADEDB
Performance Status Decreased MetaADEDB
Peripheral Artery Aneurysm MetaADEDB
Petechia MetaADEDB
Pharyngeal Haematoma MetaADEDB
Pharyngitis ADReCS
Phlebitis MetaADEDB
Photosensitive Rash MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pinguecula MetaADEDB
Pitting Oedema MetaADEDB
Pleural Effusion MetaADEDB
Pneumococcal Sepsis MetaADEDB
Progesterone Receptor Assay MetaADEDB
Prostate Cancer Metastatic MetaADEDB
Prostatic Disorder ADReCS
Proteinuria ADReCS
Pruritus ADReCS
Pruritus Generalised MetaADEDB
Pulmonary Congestion ADReCS
Pupil Fixed MetaADEDB
Pyrexia ADReCS
Raised Liver Function Tests SIDER
Rash ADReCS
Relapsing Fever MetaADEDB
Removal Of Foreign Body MetaADEDB
Renal Artery Stenosis MetaADEDB
Renal Cyst MetaADEDB
Renal Failure ADReCS
Renal Impairment ADReCS
Respiratory Arrest ADReCS
Respiratory Tract Congestion ADReCS
Restrictive Cardiomyopathy MetaADEDB
Retroperitoneal Haematoma MetaADEDB
Rhabdomyolysis ADReCS
Rhagades MetaADEDB
Rhinitis ADReCS
Road Traffic Accident MetaADEDB
Scoliosis MetaADEDB
Sensory Loss ADReCS
Sexual Dysfunction ADReCS
Shock ADReCS
Sick Sinus Syndrome MetaADEDB
Sinus Bradycardia MetaADEDB
Sinus Disorder ADReCS
Sleep Disorder ADReCS
Sleep Disturbance SIDER
Small Intestinal Obstruction MetaADEDB
Somnolence ADReCS
Sopor MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Cord Compression MetaADEDB
Spinning Sensation MetaADEDB
Squamous Cell Carcinoma Of The Cervix MetaADEDB
Staphylococcal Infection MetaADEDB
Stent Placement MetaADEDB
Stiffness SIDER
Stress Symptoms MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subcutaneous Abscess MetaADEDB
Swelling ADReCS
Swelling Face ADReCS
Swelling Of Limb SIDER
Swollen Tongue MetaADEDB
Syncope ADReCS
Systolic Hypertension MetaADEDB
Tachycardia ADReCS
Tension ADReCS
Tension Headache MetaADEDB
Thrombocytopenia ADReCS
Thromboembolic Stroke MetaADEDB
Thyroid Mass MetaADEDB
Tinnitus PROTECT
Toe Amputation MetaADEDB
Toe Deformity MetaADEDB
Tooth Loss MetaADEDB
Tooth Repair MetaADEDB
Toxoplasmosis MetaADEDB
Tracheobronchitis ADReCS
Transient Ischaemic Attack ADReCS
Tremor ADReCS
Tubulointerstitial Nephritis MetaADEDB
Type I Hypersensitivity MetaADEDB
Upper Airway Obstruction MetaADEDB
Upper Limb Fracture MetaADEDB
Upper Limb Oedema ADReCS
Urethral Stenosis MetaADEDB
Urinary Tract Infection ADReCS
Urticaria ADReCS
Vertebroplasty MetaADEDB
Vertigo ADReCS
Vestibular Neuronitis MetaADEDB
Visual Acuity Reduced ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Vulvovaginal Candidiasis MetaADEDB
Weakness SIDER
Weight Gain MetaADEDB
Wheeze MetaADEDB
Wheezing ADReCS

InAADR: Drug-Protein-ADRs database