InAADR

Drug Information

Drug Name: Idarubicin (58957-92-9)
PubChem ID: 42890
SMILES: C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O
InchiKey: XDXDZDZNSLXDNA-TZNDIEGXSA-N
Therapeutic Category: Antibiotics, Antineoplastic Agents, Enzyme Inhibitors, Topoisomerase II Inhibitors, Topoisomerase Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 497.5
LogP: 1.0203
Ring Count: 2
Hydrogen Bond Acceptor Count: 10
Hydrogen Bond Donor Count: 5
Total Polar Surface Area: 176.61

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp SIDER
Abdominal Pain ADReCS
Accident MetaADEDB
Acral Erythema SIDER
Acute Kidney Injury MetaADEDB
Acute Leukaemia SIDER
Aggression ADReCS
Alopecia ADReCS
Anaemia ADReCS
Anaesthesia MetaADEDB
Anaphylactic Shock ADReCS
Angiitis MetaADEDB
Anorexia ADReCS
Aortic Arteriosclerosis MetaADEDB
Apgar Score Low MetaADEDB
Aplasia ADReCS
Arrhythmia ADReCS
Aspergilloma MetaADEDB
Asystole MetaADEDB
Atrial Fibrillation ADReCS
Bacterial Toxaemia MetaADEDB
Bence Jones Protein Urine MetaADEDB
Birth Trauma MetaADEDB
Blood Bilirubin Unconjugated Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Creatine Phosphokinase Bb Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Uric Acid Decreased MetaADEDB
Blood Uric Acid Increased ADReCS
Body Temperature Increased ADReCS
Bone Marrow Depression MetaADEDB
Bone Marrow Failure ADReCS
Bradycardia Foetal MetaADEDB
Bruise MetaADEDB
Bundle Branch Block ADReCS
Burning Sensation ADReCS
C-Reactive Protein Increased MetaADEDB
Caesarean Section MetaADEDB
Cardiac Disorder ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardiomyopathies MetaADEDB
Cardiomyopathy Dilated MetaADEDB
Cardiovascular Disorder MetaADEDB
Central Nervous System Infection MetaADEDB
Cerebellar Syndrome ADReCS
Chest Pain ADReCS
Cholangiolitis MetaADEDB
Clostridium Bacteraemia MetaADEDB
Colitis ADReCS
Condition Aggravated MetaADEDB
Convulsion ADReCS
Cramp Muscle SIDER
Cystitis MetaADEDB
Decreased Appetite ADReCS
Dehydration ADReCS
Dermatitis ADReCS
Dermatitis Medicamentosa MetaADEDB
Dermatosis ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disease Of Liver MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Embolism ADReCS
Embolism Venous ADReCS
Endocarditis MetaADEDB
Engraftment Syndrome MetaADEDB
Enterocolitis ADReCS
Erythema ADReCS
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Fatty Liver MetaADEDB
Febrile Neutropenia MetaADEDB
Fever MetaADEDB
Fluid Overload ADReCS
Foetal Distress Syndrome MetaADEDB
Foetal Heart Rate MetaADEDB
Foetal Heart Rate Deceleration MetaADEDB
Foetal Movements Decreased MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Toxicity ADReCS
Haematemesis MetaADEDB
Haemoglobin ADReCS
Haemolytic Anaemia MetaADEDB
Haemophilia MetaADEDB
Haemorrhage ADReCS
Haemorrhage Intracranial MetaADEDB
Haemosiderosis MetaADEDB
Haemostasis MetaADEDB
Headache ADReCS
Heart Diseases MetaADEDB
Heart Failure MetaADEDB
Heart Failure Diastolic MetaADEDB
Hemorrhage MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepaplastin Decreased MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatic Necrosis MetaADEDB
Hepatic Veno-Occlusive Disease MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hot Flush ADReCS
Hypersensitivity ADReCS
Hyperuricaemia ADReCS
Hypokalaemia MetaADEDB
Hypoxia MetaADEDB
Ichthyosis ADReCS
Ichthyosis Acquired ADReCS
Ild MetaADEDB
Incorrect Dose Administered MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection ADReCS
Infusion Site Infection MetaADEDB
Injection Site Urticaria ADReCS
Intracranial Venous Sinus Thrombosis MetaADEDB
Kidney Diseases MetaADEDB
Leukemia MetaADEDB
Leukemia Myeloid Acute MetaADEDB
Leukemia Promyelocytic Acute MetaADEDB
Leukemia Radiation-Induced MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia ADReCS
Liver Diseases MetaADEDB
Local Reaction SIDER
Lung Disorder ADReCS
Lymphoma MetaADEDB
Lymphoma Non-Hodgkin MetaADEDB
Lymphoma T-Cell MetaADEDB
Mechanical Ventilation MetaADEDB
Menopausal Symptoms ADReCS
Mental Status Changes ADReCS
Mitochondrial Diseases MetaADEDB
Mucormycosis MetaADEDB
Mucosal Inflammation ADReCS
Mucositis MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Spasms ADReCS
Myelodysplasia MetaADEDB
Myelodysplastic Syndrome ADReCS
Myelodysplastic Syndromes MetaADEDB
Myelosuppression SIDER
Myocardial Depression ADReCS
Myocarditis ADReCS
Nausea ADReCS
Necrosis MetaADEDB
Necrotising Fasciitis MetaADEDB
Neoplasms MetaADEDB
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
Neutropenic Colitis ADReCS
Neutropenic Enterocolitis ADReCS
No Adverse Drug Effect MetaADEDB
Obstructive Airways Disorder MetaADEDB
Oesophagitis ADReCS
Pain MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome ADReCS
Pancytopenia ADReCS
Papilledema MetaADEDB
Pericarditis ADReCS
Phlebitis ADReCS
Phlebothrombosis MetaADEDB
Placental Disorder MetaADEDB
Platelet Transfusion MetaADEDB
Premature Baby MetaADEDB
Pruritus ADReCS
Pseudotumor Cerebri MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Arrest MetaADEDB
Pyrexia ADReCS
Radiation Recall Reaction (Dermatologic) SIDER
Rash ADReCS
Rash Generalised ADReCS
Recall Phenomenon ADReCS
Recurrence MetaADEDB
Redness SIDER
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Seizures SIDER
Sepsis ADReCS
Septicemia SIDER
Shock ADReCS
Sick Sinus Syndrome MetaADEDB
Sinus Tachycardia ADReCS
Sinus Thrombosis Intracranial MetaADEDB
Skin Hyperpigmentation ADReCS
Slow Virus Infection MetaADEDB
Small For Dates Baby MetaADEDB
Stomatitis ADReCS
Subcutaneous Emphysema MetaADEDB
Tachyarrhythmia ADReCS
Tachycardia ADReCS
Tachycardia Supraventricular MetaADEDB
Thrombocytopenia ADReCS
Thromboembolism ADReCS
Thrombophlebitis ADReCS
Thrombosis MetaADEDB
Thrombotic Microangiopathy MetaADEDB
Ulcer ADReCS
Umbilical Cord Abnormality MetaADEDB
Urticaria ADReCS
Ventricular Dysfunction Left MetaADEDB
Vomiting ADReCS
Vulvitis MetaADEDB

InAADR: Drug-Protein-ADRs database