InAADR

Drug Information

Drug Name: Griseofulvin (126-07-8)
PubChem ID: 441140
SMILES: C[C@@H]1CC(=O)C=C([C@]12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
InchiKey: DDUHZTYCFQRHIY-RBHXEPJQSA-N
Therapeutic Category: Anti-Infective Agents, Antifungal Agents

Computed Drug Properties

Molecular Weight (dalton): 352.77
LogP: 2.8103
Ring Count: 1
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 71.06

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Phenobarbital (50-06-6) Abolished Antifungal Effects Of Griseofulvin Antagonistic Not fully understood AN EFFECT OF PHENOBARBITONE ON BLOOD-LEVELS OF GRISEOFULVIN IN MAN
Bromocriptine (25614-03-3) Reduce The Efficacy Of Bromocriptine Antagonistic Unknown Metabolic and clinical studies on patients with acromegaly treated with bromocriptine over 22 months

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Agranulocytosis ADReCS
Anemia MetaADEDB
Angioedema ADReCS
Asthenia ADReCS
Candidiasis ADReCS
Carcinoma Hepatocellular MetaADEDB
Central Nervous System Diseases MetaADEDB
Cholestasis MetaADEDB
Cholestasis Intrahepatic MetaADEDB
Confusional State ADReCS
Congenital Abnormalities MetaADEDB
Depressive Disorder MetaADEDB
Dermatitis ADReCS
Dermatomycoses MetaADEDB
Diarrhoea ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drug Toxicity MetaADEDB
Dyspepsia ADReCS
Encephalitis MetaADEDB
Epigastric Discomfort ADReCS
Epigastric Distress SIDER
Epilepsy MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Fever MetaADEDB
Headache ADReCS
Hematuria MetaADEDB
Hepatitis MetaADEDB
Hepatomegaly MetaADEDB
Hypersensitivity ADReCS
Inflammation MetaADEDB
Insomnia ADReCS
Jaundice Obstructive MetaADEDB
Kidney Diseases MetaADEDB
Leukopenia ADReCS
Liver Cirrhosis MetaADEDB
Liver Neoplasms MetaADEDB
Liver Neoplasms Experimental MetaADEDB
Lupus Erythematosus Systemic MetaADEDB
Movement Disorder ADReCS
Mucocutaneous Lymph Node Syndrome MetaADEDB
Muscular Diseases MetaADEDB
Mycoses MetaADEDB
Myositis MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Nephritis Interstitial MetaADEDB
Nephrotic Syndrome MetaADEDB
Oedema ADReCS
Onychomycosis MetaADEDB
Oral Candidiasis ADReCS
Oral Thrush ADReCS
Paraesthesia ADReCS
Paresthesia MetaADEDB
Paresthesia Of Limbs ADReCS
Porphyrias Hepatic MetaADEDB
Protein Urine Present ADReCS
Proteinuria ADReCS
Protoporphyria Erythropoietic MetaADEDB
Psychoses Substance-Induced MetaADEDB
Pyuria MetaADEDB
Rash ADReCS
Raynaud Disease MetaADEDB
Renal Insufficiency MetaADEDB
Scleroderma Systemic MetaADEDB
Thyroid Neoplasms MetaADEDB
Tinea MetaADEDB
Tinea Capitis MetaADEDB
Tinea Pedis MetaADEDB
Urticaria ADReCS
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database