InAADR

Drug Information

Drug Name: Granisetron (109889-09-0)
PubChem ID: 86287410
SMILES: [2H]C([2H])([2H])N1C2=CC=CC=C2C(=N1)C(=O)NC3C[C@H]4CCC[C@@H](C3)N4C
InchiKey: MFWNKCLOYSRHCJ-GHZBYRHTSA-N
Therapeutic Category: Antiemetics, Autonomic Agents, Central Nervous System Agents, Gastrointestinal Agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Serotonin Agents, Serotonin Antagonists

Computed Drug Properties

Molecular Weight (dalton): 315.435
LogP: 2.3184
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 50.16

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Mass MetaADEDB
Abdominal Pain ADReCS
Abdominal Rigidity MetaADEDB
Acid Reflux MetaADEDB
Actinomycosis MetaADEDB
Acute Abdomen MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Graft Versus Host Disease MetaADEDB
Acute Graft Versus Host Disease In Liver MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adh Inappropriate MetaADEDB
Adrenal Neoplasm MetaADEDB
Adverse Drug Effect MetaADEDB
Adynamic Ileus MetaADEDB
Agitation ADReCS
Alanine Aminotransferase Increased ADReCS
Albumin Globulin Ratio Decreased MetaADEDB
Alopecia ADReCS
Alveolitis MetaADEDB
Anaemia ADReCS
Analgesic Drug Level Above Therapeutic MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anastomotic Ulcer MetaADEDB
Angina MetaADEDB
Angina Pectoris ADReCS
Anhedonia MetaADEDB
Anorexia MetaADEDB
Antithrombin Iii Decreased MetaADEDB
Anxiety ADReCS
Aortic Dissection MetaADEDB
Application Site Erythema PROTECT
Application Site Irritation PROTECT
Application Site Pain PROTECT
Application Site Pruritus PROTECT
Application Site Rash PROTECT
Application Site Reaction PROTECT
Arrhythmia ADReCS
Arterial Occlusive Disease MetaADEDB
Arteriosclerosis MetaADEDB
Arthralgia PROTECT
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrial Septal Defect MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block ADReCS
Attention Deficit/Hyperactivity Disorder MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Birth Defect MetaADEDB
Blast Crisis In Myelogenous Leukaemia MetaADEDB
Bleeding Gums MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Fibrinogen MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Abnormal MetaADEDB
Blood Urea Abnormal MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased ADReCS
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Disorder MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Operation MetaADEDB
Bradycardia ADReCS
Bradypnoea MetaADEDB
Brain Oedema MetaADEDB
Breast Cancer Metastatic MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchitis MetaADEDB
Bulbar Palsy MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Calcification Metastatic MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carbohydrate Antigen 19-9 MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Murmur MetaADEDB
Cardiac Tamponade MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiopulmonary Failure MetaADEDB
Cartilage Development Disorder MetaADEDB
Catheter Placement MetaADEDB
Catheter Related Complication MetaADEDB
Catheter Related Infection MetaADEDB
Catheter Removal MetaADEDB
Cellulitis MetaADEDB
Central Nervous System Stimulation ADReCS
Central Venous Catheterisation MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cervicalgia MetaADEDB
Cervicitis MetaADEDB
Cervicobrachial Syndrome MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Tube Insertion MetaADEDB
Chill MetaADEDB
Choking Sensation MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cmv Infection MetaADEDB
Cold Extremities MetaADEDB
Cold Sweat MetaADEDB
Colitis MetaADEDB
Colitis Ischaemic MetaADEDB
Colitis Pseudomembranous MetaADEDB
Completed Suicide MetaADEDB
Concomitant Disease Progression MetaADEDB
Condition Aggravated MetaADEDB
Congenital Heart Disease MetaADEDB
Congenital Mitral Valve Stenosis MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Convulsions Grand Mal MetaADEDB
Coronary Angioplasty MetaADEDB
Coronary Artery Restenosis MetaADEDB
Corynebacterium Infection MetaADEDB
Cough ADReCS
Craniotomy MetaADEDB
Csf Monocyte Count Decreased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Debridement MetaADEDB
Decreased Appetite ADReCS
Decreased Interest MetaADEDB
Deep Vein Thromboses MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dental Caries MetaADEDB
Dental Fistula MetaADEDB
Dental Pain MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Disturbance In Attention MetaADEDB
Diverticulitis MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Effect Prolonged MetaADEDB
Drug Interaction SIDER
Drug Toxicity MetaADEDB
Dry Mouth PROTECT
Duodenal Ulcer MetaADEDB
Dysgeusia ADReCS
Dyskinesia PROTECT
Dyspepsia ADReCS
Dyspnoea ADReCS
Dystonia PROTECT
Dysuria MetaADEDB
Ear Ache MetaADEDB
Ear Haemorrhage MetaADEDB
Early Morning Awakening MetaADEDB
Edema Extremities MetaADEDB
Electrocardiogram Abnormal ADReCS
Electrocardiogram Poor R-Wave Progression MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrocardiogram Qt Prolonged ADReCS
Electrocardiogram T Wave Abnormal MetaADEDB
Electrolyte Disorder MetaADEDB
Embolism Infective MetaADEDB
Emotional Distress MetaADEDB
Encephalitis Herpes MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Decreased MetaADEDB
Epstein-Barr Virus Associated Lymphoproliferative Disorder MetaADEDB
Erectile Dysfunction MetaADEDB
Eruption MetaADEDB
Erythema MetaADEDB
External Ear Infection MetaADEDB
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Eye Rolling MetaADEDB
Fat Necrosis MetaADEDB
Fatigue MetaADEDB
Febrile Infection MetaADEDB
Febrile Neutropenia MetaADEDB
Feeding Tube Insertion MetaADEDB
Fibromyalgia MetaADEDB
Flatulence ADReCS
Floaters MetaADEDB
Flushing PROTECT
Foetal Hypokinesia MetaADEDB
Folate Deficiency MetaADEDB
Fungal Disease MetaADEDB
Gamma-Glutamyltransferase Increased PROTECT
Gardnerella Infection MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Motility Disorder MetaADEDB
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Generalised Oedema PROTECT
Gingival Erythema MetaADEDB
Gingival Oedema MetaADEDB
Gingival Pain MetaADEDB
Globulins Increased MetaADEDB
Granulocyte Count Decreased MetaADEDB
Granulocytosis MetaADEDB
Gynaecomastia MetaADEDB
Haematochezia MetaADEDB
Haemorrhoids MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Hematoma Subdural MetaADEDB
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Function Abnormal MetaADEDB
Hepatic Mass MetaADEDB
Hepatic Neoplasia MetaADEDB
Hernia Hiatal MetaADEDB
Herpes Simplex MetaADEDB
Hiccough MetaADEDB
Hip Arthroplasty MetaADEDB
Hip Surgery MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hyperammonaemia MetaADEDB
Hyperkeratosis MetaADEDB
Hyperlipaemia MetaADEDB
Hyperphosphataemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertensive Heart Disease MetaADEDB
Hypoaesthesia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypokalaemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypotension ADReCS
Hysterectomy MetaADEDB
Ild MetaADEDB
Immunodeficiency Congenital MetaADEDB
Impaired Healing MetaADEDB
Incontinence MetaADEDB
Increased Bronchial Secretion ADReCS
Increased White Blood Cell Count MetaADEDB
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Infusion Related Reaction MetaADEDB
Insomnia ADReCS
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Infarction MetaADEDB
Intestinal Obstruction MetaADEDB
Ischias MetaADEDB
Jaw Operation MetaADEDB
Joint Effusion MetaADEDB
Joint Injury MetaADEDB
Klebsiella Sepsis MetaADEDB
Left Atrial Dilatation MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leucopenia MetaADEDB
Leukocytosis ADReCS
Leukodystrophy MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Liver Transplant Rejection MetaADEDB
Loose Tooth MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lung Neoplasm MetaADEDB
Lymph Node Palpable MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Lymphedema MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Malignant Pleural Effusion MetaADEDB
Malnourished MetaADEDB
Maxillofacial Operation MetaADEDB
Mental Status Changes MetaADEDB
Metaplasia MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Chest Wall MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Lung MetaADEDB
Metastases To Pancreas MetaADEDB
Metastases To Spine MetaADEDB
Micturition Urgency MetaADEDB
Middle Ear Inflammation MetaADEDB
Mitral Valve Disease MetaADEDB
Mitral Valve Prolapse MetaADEDB
Motor Dysfunction MetaADEDB
Mouth Bleeding MetaADEDB
Mucosal Inflammation MetaADEDB
Mucous Membrane Disorder MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myelitis MetaADEDB
Myelodysplasia MetaADEDB
Nausea ADReCS
Neck Mass MetaADEDB
Nephrolithiasis MetaADEDB
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutropenic Sepsis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Neutrophilia MetaADEDB
Nodule MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Nutritional Condition Abnormal MetaADEDB
Obstructive Airways Disorder MetaADEDB
Oliguria ADReCS
Oophorectomy Bilateral MetaADEDB
Oral Cavity Fistula MetaADEDB
Oral Disorder MetaADEDB
Oral Herpes MetaADEDB
Oropharyngeal Pain MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Osteosarcoma Metastatic MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Painful Respiration MetaADEDB
Pallor MetaADEDB
Pancreatic Cyst MetaADEDB
Pancreatitis MetaADEDB
Paraparesis MetaADEDB
Pericardial Drainage MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Excision MetaADEDB
Pericarditis MetaADEDB
Perivascular Dermatitis MetaADEDB
Petechia MetaADEDB
Pilonidal Cyst MetaADEDB
Platelet Count MetaADEDB
Platelet Transfusion MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumonia Cytomegaloviral MetaADEDB
Pneumothorax MetaADEDB
Postictal State MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Primary Sequestrum MetaADEDB
Proctalgia MetaADEDB
Productive Cough MetaADEDB
Prostate Cancer Recurrent MetaADEDB
Prostatomegaly MetaADEDB
Protein Total Decreased MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Mass MetaADEDB
Purulent Discharge MetaADEDB
Pyelonephritis MetaADEDB
Pyogenic Granuloma MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Rectal Ulcer MetaADEDB
Red Blood Cell Count Increased MetaADEDB
Renal Impairment MetaADEDB
Reperfusion Arrhythmia ADReCS
Respiratory Tract Congestion MetaADEDB
Retching PROTECT
Rib Fracture MetaADEDB
Risus Sardonicus MetaADEDB
Sarcoidosis MetaADEDB
Scoliosis MetaADEDB
Scrotal Swelling MetaADEDB
Sequestrectomy MetaADEDB
Sexual Dysfunctions Psychological MetaADEDB
Shock ADReCS
Shunt Malfunction MetaADEDB
Sigmoid Neoplasms MetaADEDB
Sinus Bradycardia ADReCS
Sinusitis MetaADEDB
Skin Desquamation MetaADEDB
Skin Injury MetaADEDB
Skin Oedema MetaADEDB
Skin Plaque MetaADEDB
Sleep Disorder MetaADEDB
Somnolence ADReCS
Spinal Column Stenosis MetaADEDB
Spinal Osteoarthritis MetaADEDB
Splenic Lesion MetaADEDB
Sputum Increased ADReCS
Staphylococcal Infection MetaADEDB
Stress Fracture MetaADEDB
Subdural Haematoma Evacuation MetaADEDB
Syncope ADReCS
Tachycardia ADReCS
Tetany MetaADEDB
Thoracotomy MetaADEDB
Thrombocytopenia ADReCS
Thrombotic Microangiopathy MetaADEDB
Thyroid Neoplasia MetaADEDB
Thyroiditis MetaADEDB
Tonsillitis MetaADEDB
Tooth Extraction MetaADEDB
Tooth Infection MetaADEDB
Toxicologic Test Abnormal MetaADEDB
Transaminases Increased PROTECT
Umbilical Hernia MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urinary Tract Infection ADReCS
Urine Flow Decreased MetaADEDB
Urticaria ADReCS
Vena Cava Thrombosis MetaADEDB
Venoocclusive Liver Disease MetaADEDB
Venous Thrombosis Limb MetaADEDB
Ventricular Extrasystoles ADReCS
Vertigo PROTECT
Viral Upper Respiratory Tract Infection MetaADEDB
Visceral Congestion MetaADEDB
Vision Disorders MetaADEDB
Visual Disturbance MetaADEDB
Vitamin K Deficiency MetaADEDB
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database