InAADR

Drug Information

Drug Name: Gemfibrozil (25812-30-0)
PubChem ID: 3463
SMILES: CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O
InchiKey: HEMJJKBWTPKOJG-UHFFFAOYSA-N
Therapeutic Category: Antimetabolites, Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme Inhibitors, Enzyme Inhibitors, Hypolipidemic Agents, Lipid Regulating Agents

Computed Drug Properties

Molecular Weight (dalton): 250.338
LogP: 3.57324
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 46.53

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Carbamazepine (298-46-4) Ataxia Synergistic uncertain Therapeutic drug monitoring—antiepileptic drugs

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness MetaADEDB
Abnormal Dreams MetaADEDB
Abnormal Movements MetaADEDB
Abnormal Vision MetaADEDB
Abscess Oral MetaADEDB
Accelerated Hypertension MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Acute Appendicitis SIDER
Acute Kidney Injury MetaADEDB
Acute Prerenal Failure MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenovirus Infection MetaADEDB
Adynamic Ileus MetaADEDB
Affective Disorder MetaADEDB
Ageusia MetaADEDB
Alopecia ADReCS
Alpha Haemolytic Streptococcal Infection MetaADEDB
Amnesia MetaADEDB
Anaemia ADReCS
Anaemia Of Chronic Disease MetaADEDB
Anaesthesia MetaADEDB
Anal Fissure MetaADEDB
Anal Haemorrhage MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angina MetaADEDB
Angina Unstable MetaADEDB
Angioedema ADReCS
Angiopathy ADReCS
Antinuclear Antibody Positive ADReCS
Anuria MetaADEDB
Anxiety MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aphonia MetaADEDB
Apoptosis MetaADEDB
Appendicitis ADReCS
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriospasm Coronary MetaADEDB
Arthralgia ADReCS
Arthritis MetaADEDB
Arthritis Bacterial MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Assisted Fertilisation ADReCS
Asthenia ADReCS
Atrial Ectopic Beats MetaADEDB
Atrial Fibrillation ADReCS
Atrial Thrombosis MetaADEDB
Atrophy MetaADEDB
Azotaemia MetaADEDB
Back Pain MetaADEDB
Bacterial Infection ADReCS
Bacterial Toxaemia MetaADEDB
Biliary Fibrosis MetaADEDB
Bipolar Disorder MetaADEDB
Bleeding Gums MetaADEDB
Blood Acid Phosphatase Increased ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased ADReCS
Blood Chloride Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatine Increased ADReCS
Blood Creatine Phosphokinase Abnormal ADReCS
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Disorder MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature MetaADEDB
Bone Density Decreased MetaADEDB
Bone Marrow Depression SIDER
Bone Marrow Failure ADReCS
Bone Neoplasm Malignant MetaADEDB
Bradypnoea MetaADEDB
Brain Concussion MetaADEDB
Bronchitis MetaADEDB
Bronchitis MetaADEDB
Bruxism MetaADEDB
Bundle Branch Block Right MetaADEDB
Bursitis MetaADEDB
Buttock Pain MetaADEDB
Calculus Urinary MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Operation MetaADEDB
Cardiogenic Shock MetaADEDB
Carpal Tunnel MetaADEDB
Cataract ADReCS
Catheter Related Complication MetaADEDB
Catheterisation Cardiac MetaADEDB
Cellulitis MetaADEDB
Central Line Infection MetaADEDB
Cerebral Haemorrhage ADReCS
Cervical Discharge MetaADEDB
Cervical Neuritis MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Chill MetaADEDB
Choking Sensation MetaADEDB
Cholecystitis ADReCS
Cholecystitis Acute MetaADEDB
Cholelithiasis ADReCS
Cholestasis Intrahepatic MetaADEDB
Chronic Fatigue Syndrome MetaADEDB
Chronic Graft Versus Host Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Cold Extremities MetaADEDB
Colitis ADReCS
Colitis Pseudomembranous MetaADEDB
Colonic Polyp MetaADEDB
Common Cold SIDER
Compartment Syndromes MetaADEDB
Complement Factor C1 Decreased MetaADEDB
Complications Of Transplanted Kidney MetaADEDB
Concomitant Disease Progression MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Congenital Tricuspid Valve Incompetence MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coronary Artery Occlusion MetaADEDB
Coronary Stenosis MetaADEDB
Corynebacterium Infection MetaADEDB
Cough ADReCS
Creatine Phosphokinase Increased SIDER
Cutaneous Ulcer MetaADEDB
Deglutition Disorder MetaADEDB
Dental Abscess MetaADEDB
Depressed Mood MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Exfoliative ADReCS
Dermatitis Medicamentosa MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Eye Disease MetaADEDB
Diabetic Nephropathy MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Dilatation Ventricular MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Disorder Retinal MetaADEDB
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Dose Omission MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction SIDER
Drug Prescribing Error MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dysgeusia ADReCS
Dyslipidaemia MetaADEDB
Dyslipidemias MetaADEDB
Dyspepsia ADReCS
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Ear Ache MetaADEDB
Early Morning Awakening MetaADEDB
Echocardiogram Abnormal MetaADEDB
Eczema ADReCS
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electromechanical Dissociation MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalopathy MetaADEDB
Endocarditis MetaADEDB
Endometrial Hyperplasia MetaADEDB
Eosinophilia ADReCS
Epigastric Pain SIDER
Epistaxis MetaADEDB
Erectile Dysfunction ADReCS
Eruption MetaADEDB
Eschar MetaADEDB
Escherichia Sepsis MetaADEDB
Excess Potassium MetaADEDB
Excoriation MetaADEDB
Extrasystoles ADReCS
Extremity Necrosis MetaADEDB
Extremity Pain MetaADEDB
Eye Inflammation MetaADEDB
Facial Flushing MetaADEDB
Facial Neuralgia MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Fear Of Falling MetaADEDB
Feeling Abnormal ADReCS
Feeling Guilty MetaADEDB
Fertility Male Decreased SIDER
Fertilization SIDER
Fib MetaADEDB
Finger Amputation MetaADEDB
Flank Pain MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Formication MetaADEDB
Full Blood Count Decreased MetaADEDB
Gallbladder Operation ADReCS
Gastric Ulcer MetaADEDB
Gastric Ulcer Perforated MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Necrosis MetaADEDB
Gingival Infection MetaADEDB
Glomerulonephritis MetaADEDB
Glucose Intolerance MetaADEDB
Gout ADReCS
Growth Hormone Deficiency MetaADEDB
Haematochezia MetaADEDB
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhoids MetaADEDB
Hair Growth Abnormal MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatic Neoplasm Malignant ADReCS
Hepatitis MetaADEDB
Hepatomegaly MetaADEDB
Hernia Hiatal MetaADEDB
High Blood Pressure MetaADEDB
High Density Lipoprotein Decreased MetaADEDB
Hypercholesterolemia MetaADEDB
Hyperglycaemic Hyperosmolar Nonketotic Syndrome MetaADEDB
Hyperhidrosis MetaADEDB
Hyperlipidemias MetaADEDB
Hyperlipoproteinemia Type Iv MetaADEDB
Hyperparathyroidism MetaADEDB
Hyperphosphataemia MetaADEDB
Hyperproteinaemia MetaADEDB
Hypertonia MetaADEDB
Hypertriglyceridemia MetaADEDB
Hypertrophic Cardiomyopathy MetaADEDB
Hypoaesthesia ADReCS
Hypoalphalipoproteinemias MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypovolaemia MetaADEDB
Hysterectomy MetaADEDB
Immunosuppressant Drug Level Decreased MetaADEDB
Impaired Healing MetaADEDB
Impingement Syndrome MetaADEDB
Impotence ADReCS
Inappropriate Schedule Of Drug Administration MetaADEDB
Increased Appetite MetaADEDB
Increased Upper Airway Secretion MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infected Insect Bite MetaADEDB
Infection ADReCS
Infertility Male ADReCS
Infusion Site Haematoma MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Insulin-Requiring Type 2 Diabetes Mellitus MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intestinal Obstruction MetaADEDB
Intestinal Operation MetaADEDB
Intestinal Perforation MetaADEDB
Intestinal Resection MetaADEDB
Intraocular Pressure Test MetaADEDB
Irregular Menstrual Cycle MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Jaw Fracture MetaADEDB
Joint Arthroplasty MetaADEDB
Kidney Neoplasm MetaADEDB
Kidney Pain MetaADEDB
Kidney Transplant Rejection MetaADEDB
Large Intestine Perforation MetaADEDB
Laryngeal Oedema ADReCS
Leg Amputation MetaADEDB
Lethargy MetaADEDB
Leukopenia ADReCS
Libido Decreased ADReCS
Lichenoid Keratosis MetaADEDB
Lipase MetaADEDB
Lipids Increased MetaADEDB
Liver Carcinoma SIDER
Liver Function Test Abnormal ADReCS
Localised Osteoarthritis MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lower Extremity Mass MetaADEDB
Lumbar Radiculopathy MetaADEDB
Lung Consolidation MetaADEDB
Lung Edema MetaADEDB
Lung Neoplasm MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lupus Erythematosus SIDER
Lupus-Like Syndrome ADReCS
Lymphocytic Infiltration MetaADEDB
Megacolon MetaADEDB
Melanocytic Naevus MetaADEDB
Mental Status Changes MetaADEDB
Mitral Valve Disease MetaADEDB
Motor Dysfunction MetaADEDB
Mouth Pain MetaADEDB
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myasthenia SIDER
Myelopathy MetaADEDB
Myopathy ADReCS
Myositis MetaADEDB
Nasal Sinus Congestion MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Near Syncope MetaADEDB
Negative Thoughts MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Neuritis ADReCS
Neuropathy Peripheral ADReCS
Nightmare MetaADEDB
Nodal Osteoarthritis MetaADEDB
Nodule MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Obstructive Airways Disorder MetaADEDB
Occult Blood Positive MetaADEDB
Oedema ADReCS
Onychomadesis MetaADEDB
Open Wound MetaADEDB
Oral Intake Reduced MetaADEDB
Oropharyngeal Pain MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Pain In Extremity ADReCS
Pain In Throat MetaADEDB
Pancreatitis ADReCS
Pancreatitis Chronic MetaADEDB
Pancytopenia ADReCS
Panic Disorder MetaADEDB
Paraesthesia ADReCS
Pedal Pulse Absent MetaADEDB
Periodontitis MetaADEDB
Peripheral Neuritis ADReCS
Peripheral Vascular Disorder ADReCS
Peritonitis MetaADEDB
Petechia MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngeal Disorder MetaADEDB
Pharyngitis Streptococcal MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Phosphatase Alkaline Increased SIDER
Photosensitive Rash MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pollakiuria MetaADEDB
Polyomavirus-Associated Nephropathy MetaADEDB
Polyp Colorectal MetaADEDB
Portal Hypertension MetaADEDB
Portal Triaditis MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Postoperative Infection MetaADEDB
Postoperative Wound Complication MetaADEDB
Postoperative Wound Infection MetaADEDB
Product Quality Issue MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pulmonary Congestion MetaADEDB
Rales MetaADEDB
Rash ADReCS
Raynaud Disease MetaADEDB
Reaction Gastrointestinal SIDER
Rectal Fissure MetaADEDB
Red Blood Cell Abnormality MetaADEDB
Reflux Esophagitis MetaADEDB
Renal Cyst MetaADEDB
Renal Disorder ADReCS
Renal Insufficiency MetaADEDB
Respiratory Failure MetaADEDB
Resuscitation MetaADEDB
Retinal Degeneration MetaADEDB
Retinal Oedema ADReCS
Retinal Vascular Disorder MetaADEDB
Rhabdomyolysis ADReCS
Rheumatoid Nodule MetaADEDB
Rhinitis ADReCS
Rib Fracture MetaADEDB
Scab MetaADEDB
Schizoaffective Disorder MetaADEDB
Scratch MetaADEDB
Sensory Disturbance MetaADEDB
Septic Shock MetaADEDB
Sexual Dysfunction Physiological MetaADEDB
Shock ADReCS
Sinus Bradycardia MetaADEDB
Sinus Headache MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration MetaADEDB
Skin Haemorrhage MetaADEDB
Skin Necrosis MetaADEDB
Sleep Apnea MetaADEDB
Sleep Disorder MetaADEDB
Small Intestinal Obstruction MetaADEDB
Smoker MetaADEDB
Social Avoidant Behaviour ADReCS
Somnolence ADReCS
Spinal Compression Fracture MetaADEDB
Sputum Discoloured MetaADEDB
Stress MetaADEDB
Suicidal Behaviour MetaADEDB
Syncope ADReCS
Syncope Vasovagal MetaADEDB
Synovitis ADReCS
Systemic Lupus Erythematosus ADReCS
Therapy Regimen Changed MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis MetaADEDB
Thyroid Disease MetaADEDB
Toe Amputation MetaADEDB
Tonsillar Disorder MetaADEDB
Tooth Extraction MetaADEDB
Toxoplasmosis MetaADEDB
Troponin Increased MetaADEDB
Ulcer MetaADEDB
Unevaluable Event MetaADEDB
Urinary Tract Infection ADReCS
Urinary Tract Infection Staphylococcal MetaADEDB
Urticaria ADReCS
Vascular Graft MetaADEDB
Vascular Pseudoaneurysm MetaADEDB
Vasculitis ADReCS
Venous Stasis MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Walking Aid User MetaADEDB
Weight Decreased ADReCS
Withdrawal Syndrome MetaADEDB
Withdrawn SIDER
Wound Infection Pseudomonas MetaADEDB
Wound Infection Staphylococcal MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB

InAADR: Drug-Protein-ADRs database