InAADR

Drug Information

Drug Name: Floxacillin (5250-39-5)
PubChem ID: 21319
SMILES: CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O
InchiKey: UIOFUWFRIANQPC-JKIFEVAISA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 453.879
LogP: 2.68782
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 112.74

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Tenderness MetaADEDB
Abnormal Lfts MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Prerenal Failure MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Ageusia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Alveolitis MetaADEDB
Allergic Dermatitis MetaADEDB
Anal Haemorrhage MetaADEDB
Anemia Aplastic MetaADEDB
Anemia Hemolytic MetaADEDB
Angioplasty MetaADEDB
Angle Closure Glaucoma MetaADEDB
Anion Gap Increased MetaADEDB
Anosmia MetaADEDB
Antepartum Haemorrhage MetaADEDB
Antibody Test MetaADEDB
Anticonvulsant Drug Level Increased MetaADEDB
Anuria MetaADEDB
Apathy MetaADEDB
Arteriovenous Shunt Operation MetaADEDB
Arthritis Bacterial MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Ataxia MetaADEDB
Bacteremia MetaADEDB
Bacterial Infections MetaADEDB
Bacterial Toxaemia MetaADEDB
Bad Breath MetaADEDB
Barrett Oesophagus MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Glucose Fluctuation MetaADEDB
Blood In Urine MetaADEDB
Blood Urea Decreased MetaADEDB
Body Temperature MetaADEDB
Brain Oedema MetaADEDB
Breast Disorder MetaADEDB
Breast Enlargement MetaADEDB
Breast Tenderness MetaADEDB
Bronchopneumonia MetaADEDB
Burning Sensation MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cardiogenic Shock MetaADEDB
Catheter Related Infection MetaADEDB
Catheter Site Related Reaction MetaADEDB
Cellulitis MetaADEDB
Central Line Infection MetaADEDB
Chest Infection MetaADEDB
Cholangiolitis MetaADEDB
Cholangitis MetaADEDB
Cholestasis MetaADEDB
Cholestasis Intrahepatic MetaADEDB
Choroidal Effusion MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Clotting MetaADEDB
Coagulation Factor Viii Level Decreased MetaADEDB
Coagulation Factor X Level Increased MetaADEDB
Colitis MetaADEDB
Community-Acquired Infections MetaADEDB
Coombs Positive Haemolytic Anaemia MetaADEDB
Corneal Oedema MetaADEDB
Dehydration MetaADEDB
Depression Suicidal MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatosis MetaADEDB
Device Breakage MetaADEDB
Device Dislocation MetaADEDB
Device Malfunction MetaADEDB
Dialysis MetaADEDB
Distal Intestinal Obstruction Syndrome MetaADEDB
Dizziness Exertional MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Exposure Via Breast Milk MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Drug Interaction Potentiation MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Electrocardiogram T Wave Peaked MetaADEDB
Empyema MetaADEDB
Encephalopathy MetaADEDB
Endocarditis Bacterial MetaADEDB
Enterovesical Fistula MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Eruption MetaADEDB
Erythema MetaADEDB
Erythema Nodosum MetaADEDB
Exfoliative Rash MetaADEDB
Factor Viii Inhibition MetaADEDB
Feeding Disorder MetaADEDB
Feeling Cold MetaADEDB
Flat Anterior Chamber Of Eye MetaADEDB
Gastroenteritis Salmonella MetaADEDB
Gastrointestinal Injury MetaADEDB
General Physical Health Deterioration MetaADEDB
Glasgow Coma Scale MetaADEDB
Globulinuria MetaADEDB
Granulocytosis MetaADEDB
Haemarthrosis MetaADEDB
Haemodialysis MetaADEDB
Haemothorax MetaADEDB
Hepatitis MetaADEDB
Hepatotoxicity MetaADEDB
Hyperventilation MetaADEDB
Hypomagnesaemia MetaADEDB
Hypophosphataemia MetaADEDB
Hypotonia MetaADEDB
Induration MetaADEDB
Infection MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Intentional Self-Injury MetaADEDB
International Normalised Ratio Decreased MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intraventricular Haemorrhage Neonatal MetaADEDB
Itch MetaADEDB
Jaundice MetaADEDB
Jaundice Obstructive MetaADEDB
Joint Injection MetaADEDB
Kidney Failure MetaADEDB
Lethargy MetaADEDB
Lipids Abnormal MetaADEDB
Live Birth MetaADEDB
Liver Failure MetaADEDB
Lung Fibrosis MetaADEDB
Lyell MetaADEDB
Melanocytic Naevus MetaADEDB
Meningitis Bacterial MetaADEDB
Metabolic Acidosis MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metastases To Lung MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Weakness MetaADEDB
Myoglobin Blood Increased MetaADEDB
Necrotising Fasciitis MetaADEDB
Nephritis MetaADEDB
Nephritis Interstitial MetaADEDB
Neutropenia MetaADEDB
Neutropenic Sepsis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nystagmus MetaADEDB
Onychomadesis MetaADEDB
Ototoxicity MetaADEDB
Ovulation Disorder MetaADEDB
Pain Pelvic MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Paraparesis MetaADEDB
Phlebitis MetaADEDB
Pneumonia Bacterial MetaADEDB
Porokeratosis MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Complications MetaADEDB
Postpartum Depression MetaADEDB
Pregnancy With Injectable Contraceptive MetaADEDB
Procedural Pain MetaADEDB
Proteinuria MetaADEDB
Proteus Infection MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus MetaADEDB
Pseudomonas Infection MetaADEDB
Pupil Fixed MetaADEDB
Pyomyositis MetaADEDB
Pyroglutamate Increased MetaADEDB
Pyuria MetaADEDB
Quadriparesis MetaADEDB
Rash Generalised MetaADEDB
Red Man Syndrome MetaADEDB
Renal Cortical Necrosis MetaADEDB
Renal Impairment MetaADEDB
Renal Injury MetaADEDB
Renal Ischaemia MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Rhabdomyolysis MetaADEDB
Salmonella MetaADEDB
Schizophrenia MetaADEDB
Skin Desquamation MetaADEDB
Skin Laceration MetaADEDB
Splenic Infarction MetaADEDB
Staphylococcal Abscess MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infections MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Tardive Dyskinesia MetaADEDB
Tenosynovitis MetaADEDB
Tetany MetaADEDB
Thoracotomy MetaADEDB
Tonsillar Hypertrophy MetaADEDB
Toxic Shock MetaADEDB
Treatment Failure MetaADEDB
Troponin I Increased MetaADEDB
Troponin T MetaADEDB
Type Ii Hypersensitivity MetaADEDB
Uterine Rupture MetaADEDB
Vasculitic Rash MetaADEDB
Weight Gain Poor MetaADEDB
Wheeze MetaADEDB
Wound Haemorrhage MetaADEDB
Wound Secretion MetaADEDB

InAADR: Drug-Protein-ADRs database