InAADR

Drug Information

Drug Name: Fexofenadine (83799-24-0)
PubChem ID: 3348
SMILES: CC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O
InchiKey: RWTNPBWLLIMQHL-UHFFFAOYSA-N
Therapeutic Category: Anti-Allergic Agents, Histamine Agents, Histamine Antagonists, Histamine H1 Antagonists, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 501.667
LogP: 5.5105
Ring Count: 3
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 81

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Reduce Oral Bioavability Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Discomfort ADReCS
Abdominal Hernia MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Abdominal Panniculectomy MetaADEDB
Abdominal Wound Dehiscence MetaADEDB
Abnormal Ecg MetaADEDB
Abnormal Vision MetaADEDB
Abscess Bacterial MetaADEDB
Accident MetaADEDB
Accidental Exposure MetaADEDB
Accidental Injury ADReCS
Accidental Overdose MetaADEDB
Accommodation Disorder MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acid Reflux MetaADEDB
Acne MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Sinusitis MetaADEDB
Adenopathy MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Alcoholic Liver Disease MetaADEDB
Allergic Rhinitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Amaurosis Fugax MetaADEDB
Amnesia MetaADEDB
Amyloidosis MetaADEDB
Anaemia MetaADEDB
Analgesic Drug Level Increased MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Androgen Deficiency MetaADEDB
Anemia Aplastic MetaADEDB
Angina Unstable MetaADEDB
Angioedema ADReCS
Anhedonia MetaADEDB
Anorexia MetaADEDB
Antinuclear Antibody Increased MetaADEDB
Anxiety MetaADEDB
Anxiety Disorder MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Calcification MetaADEDB
Apathy MetaADEDB
Application Site Rash MetaADEDB
Apraxia MetaADEDB
Aptyalism MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthritis MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Decreased MetaADEDB
Asteatosis MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Asthmatic Crisis MetaADEDB
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrophy MetaADEDB
Back Ache MetaADEDB
Back Injury MetaADEDB
Back Pain ADReCS
Bacterial Conjunctivitis MetaADEDB
Bad Breath MetaADEDB
Balance Disorder MetaADEDB
Barrett Oesophagus MetaADEDB
Basal Cell Carcinoma MetaADEDB
Basedow Disease MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy Lymph Gland MetaADEDB
Bladder Cancer MetaADEDB
Bladder Cancer Recurrent MetaADEDB
Bladder Spasm MetaADEDB
Bladder Suspension MetaADEDB
Bleeding Gums MetaADEDB
Blood 125-Dihydroxycholecalciferol Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Test Abnormal MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Density Decreased MetaADEDB
Bone Disorder MetaADEDB
Bone Fracture MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Fragmentation MetaADEDB
Bone Marrow Necrosis MetaADEDB
Bone Metabolism Disorder MetaADEDB
Bone Pain MetaADEDB
Bradypnoea MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Breast Microcalcification MetaADEDB
Breast Reconstruction MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchiectasis MetaADEDB
Bronchitis MetaADEDB
Bruxism MetaADEDB
Bundle Branch Block Left MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation MetaADEDB
Burning Sensation Mucosal MetaADEDB
Bursitis MetaADEDB
Buttock Pain MetaADEDB
Carbuncle MetaADEDB
Carcinoid Tumour Pulmonary MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiomyopathy MetaADEDB
Cardiospasm MetaADEDB
Carotid Artery Disease MetaADEDB
Cataract MetaADEDB
Catheter Related Infection MetaADEDB
Cellulitis MetaADEDB
Central Venous Catheterisation MetaADEDB
Cervical Myelopathy MetaADEDB
Cervical Spinal Stenosis MetaADEDB
Cervical Spine Flattening MetaADEDB
Cervicalgia MetaADEDB
Chest Discomfort ADReCS
Chest Infection MetaADEDB
Chest Pain ADReCS
Chest Tightness ADReCS
Chest X-Ray Abnormal MetaADEDB
Choking Sensation MetaADEDB
Cholecystitis Chronic MetaADEDB
Chondrocalcinosis MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Coeliac Disease MetaADEDB
Cognitive Disorder MetaADEDB
Colon Spastic MetaADEDB
Colonic Polyp MetaADEDB
Compression Fracture MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Constipated MetaADEDB
Contact Dermatitis MetaADEDB
Corneal Abrasion MetaADEDB
Coronary Artery Occlusion MetaADEDB
Cough ADReCS
Crying MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Deafness MetaADEDB
Debridement MetaADEDB
Deep Vein Thromboses MetaADEDB
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dental Care MetaADEDB
Dental Implantation MetaADEDB
Dental Pain MetaADEDB
Denture Wearer MetaADEDB
Depressed Mood MetaADEDB
Depressive Symptom MetaADEDB
Dermatitis ADReCS
Dermatitis Medicamentosa MetaADEDB
Dermographism MetaADEDB
Device Dislocation MetaADEDB
Device Failure MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Hyperosmolar Coma MetaADEDB
Diabetic Neuropathy MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Discomfort ADReCS
Disease Progression MetaADEDB
Disorder Lung MetaADEDB
Disorder Of Globe MetaADEDB
Disorder Renal MetaADEDB
Disturbance In Attention MetaADEDB
Dizziness ADReCS
Drowsiness SIDER
Drug Ineffective MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Dry Skin MetaADEDB
Dyscalculia MetaADEDB
Dysgraphia MetaADEDB
Dyshidrosis MetaADEDB
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphonia MetaADEDB
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysuria MetaADEDB
Ear Haemorrhage MetaADEDB
Ear Infection ADReCS
Ear Pain ADReCS
Early Morning Awakening MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Economic Problem MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Embolism Pulmonary MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Empyema MetaADEDB
Endodontic Procedure MetaADEDB
Enlarged Liver MetaADEDB
Enlarged Spleen MetaADEDB
Enterocolitis Infectious MetaADEDB
Epistaxis ADReCS
Eruption MetaADEDB
Erythema Multiforme MetaADEDB
Essential Hypertension MetaADEDB
Eustachian Tube Disorder MetaADEDB
Excessive Thirst MetaADEDB
Extrasystoles Ventricular MetaADEDB
Extremity Pain MetaADEDB
Eye Injury MetaADEDB
Facial Spasm MetaADEDB
Factor V Leiden Mutation MetaADEDB
Failure To Thrive MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Feeling Abnormal MetaADEDB
Fib MetaADEDB
Fibromyalgia MetaADEDB
Fistula MetaADEDB
Flatulence ADReCS
Floaters MetaADEDB
Flu MetaADEDB
Flushing ADReCS
Food Poisoning MetaADEDB
Foot Fracture MetaADEDB
Foreign Body In Eye MetaADEDB
Foreign Body Sensation In Eyes MetaADEDB
Formication MetaADEDB
Fracture Delayed Union MetaADEDB
Fracture Nonunion MetaADEDB
Fractured Pelvis Nos MetaADEDB
Fractured Sacrum MetaADEDB
Gallbladder Operation MetaADEDB
Gambling MetaADEDB
Gastric Disorder ADReCS
Gastric Hypomotility MetaADEDB
Gastrointestinal Motility Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Ulcer MetaADEDB
Generalised Anxiety Disorder MetaADEDB
Generalised Erythema MetaADEDB
Genital Rash MetaADEDB
Gingival Disorder MetaADEDB
Gingival Hyperplasia MetaADEDB
Gingival Oedema MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis MetaADEDB
Goiter MetaADEDB
Granuloma MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Hand-Foot-And-Mouth Disease MetaADEDB
Hay Fever MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Rate Increased MetaADEDB
Heart Valve Incompetence MetaADEDB
Hernia MetaADEDB
Herpes Zoster MetaADEDB
High Blood Pressure MetaADEDB
High Density Lipoprotein Decreased MetaADEDB
Hip Fracture MetaADEDB
Hodgkin Disease MetaADEDB
Hyperalimentation MetaADEDB
Hyperhidrosis MetaADEDB
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypertonia MetaADEDB
Hypertonic Bladder MetaADEDB
Hyperventilation MetaADEDB
Hypoaesthesia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypoparathyroidism MetaADEDB
Hypophagia MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypothyroid MetaADEDB
Hypovolaemia MetaADEDB
Impaired Driving Ability MetaADEDB
Impaired Gastric Emptying MetaADEDB
Impingement Syndrome MetaADEDB
Incontinence MetaADEDB
Incorrect Dose Administered MetaADEDB
Incorrect Drug Administration Rate MetaADEDB
Increased Appetite ADReCS
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Induced Labour MetaADEDB
Infection ADReCS
Infection Viral MetaADEDB
Influenza ADReCS
Ingrown Hair MetaADEDB
Injection Site Dermatitis MetaADEDB
Injection Site Discomfort MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Irritation MetaADEDB
Injection Site Pruritus MetaADEDB
Inner Ear Disorder MetaADEDB
Insomnia ADReCS
Insulin-Requiring Type 2 Diabetes Mellitus MetaADEDB
Intention Tremor MetaADEDB
International Normalised Ratio Decreased MetaADEDB
Intertrigo MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intervertebral Disc Operation MetaADEDB
Intestinal Functional Disorder MetaADEDB
Intestinal Obstruction MetaADEDB
Intrinsic Factor Antibody Negative MetaADEDB
Irritation Skin MetaADEDB
Ischaemia MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Ischias MetaADEDB
Itch MetaADEDB
Joint Arthroplasty MetaADEDB
Joint Effusion MetaADEDB
Joint Injury MetaADEDB
Keratitis Sicca MetaADEDB
Kidney Failure MetaADEDB
Lacrimation Increased MetaADEDB
Laryngeal Disorder MetaADEDB
Leukoplakia MetaADEDB
Life Expectancy Shortened MetaADEDB
Ligament Rupture MetaADEDB
Ligament Sprain MetaADEDB
Limb Crushing Injury MetaADEDB
Limb Deformity MetaADEDB
Limb Discomfort MetaADEDB
Lipids Increased MetaADEDB
Lung Consolidation MetaADEDB
Lung Edema MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Lupus-Like Syndrome MetaADEDB
Lymphadenectomy MetaADEDB
Lymphedema MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphoproliferative Disorder MetaADEDB
Macrophage Activation MetaADEDB
Malignant Pleural Effusion MetaADEDB
Medical Device Removal MetaADEDB
Meningioma MetaADEDB
Menopausal Disorder MetaADEDB
Metastases To Central Nervous System MetaADEDB
Middle Ear Inflammation MetaADEDB
Migraine MetaADEDB
Migraine With Aura MetaADEDB
Milia MetaADEDB
Mitral Valve Stenosis MetaADEDB
Monocyte Percentage Decreased MetaADEDB
Mononeuritis MetaADEDB
Mood Altered MetaADEDB
Motor Dysfunction MetaADEDB
Mouth Ulcer MetaADEDB
Mucosal Dryness MetaADEDB
Multiple Injuries MetaADEDB
Muscle Tightness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder MetaADEDB
Musculoskeletal Pain MetaADEDB
Myalgia ADReCS
Myelopathy MetaADEDB
Myringitis MetaADEDB
Nail Tinea MetaADEDB
Nasal Congestion MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nephrolithiasis MetaADEDB
Nephrotic Syndrome MetaADEDB
Nerve Root Compression MetaADEDB
Nervousness ADReCS
Neuralgia MetaADEDB
Neuropathy Peripheral MetaADEDB
Nightmare ADReCS
Nodule MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Oesophageal Dilatation MetaADEDB
Off Label Use MetaADEDB
Optic Ischaemic Neuropathy MetaADEDB
Oral Cavity Fistula MetaADEDB
Oral Mucosal Exfoliation MetaADEDB
Oral Neoplasm MetaADEDB
Oral Polypectomy MetaADEDB
Oral Surgery MetaADEDB
Orchitis MetaADEDB
Oropharyngeal Pain MetaADEDB
Oropharyngeal Plaque MetaADEDB
Osteoarthritis MetaADEDB
Osteolysis MetaADEDB
Osteomyelitis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Osteosclerosis MetaADEDB
Otitis SIDER
Otitis Media ADReCS
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Palpitation MetaADEDB
Palpitations ADReCS
Pancreatitis MetaADEDB
Paranoia ADReCS
Partner Stress MetaADEDB
Patellofemoral Pain Syndrome MetaADEDB
Pelvic Fluid Collection MetaADEDB
Penile Pain MetaADEDB
Perennial Allergic Rhinitis SIDER
Periodontitis MetaADEDB
Peripheral Nerve Transposition MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Petechia MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngeal Disorder MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Physical Disability MetaADEDB
Pleurisy MetaADEDB
Pleurodesis MetaADEDB
Pneumothorax MetaADEDB
Pollakiuria ADReCS
Polyneuropathy MetaADEDB
Polyp MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Haematoma MetaADEDB
Post Procedural Pain MetaADEDB
Post Streptococcal Glomerulonephritis MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Posture Abnormal MetaADEDB
Prescribed Overdose MetaADEDB
Primary Sequestrum MetaADEDB
Procedural Hypertension MetaADEDB
Productive Cough MetaADEDB
Protein Total Increased MetaADEDB
Prothrombin Level Increased MetaADEDB
Pruritus ADReCS
Psychiatric Symptom MetaADEDB
Psychosexual Disorder MetaADEDB
Psychotic Disorder ADReCS
Pulmonary Eosinophilia MetaADEDB
Pulmonary Infarction MetaADEDB
Pulse Pressure Decreased MetaADEDB
Pyrexia ADReCS
Radiation Pneumonitis MetaADEDB
Radicular Syndrome MetaADEDB
Radiotherapy MetaADEDB
Rash ADReCS
Raynaud Phenomenon MetaADEDB
Reflux Esophagitis MetaADEDB
Renal Function Test Abnormal MetaADEDB
Renal Infarct MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Tract Infection ADReCS
Resuscitation MetaADEDB
Retinal Injury MetaADEDB
Retinal Vasculitis MetaADEDB
Rhinitis Perennial ADReCS
Rhinorrhoea ADReCS
Right Heart Failure MetaADEDB
Road Traffic Accident MetaADEDB
Sarcosinaemia SIDER
Scar MetaADEDB
Schamberg Disease MetaADEDB
Scleroderma MetaADEDB
Sensitivity Of Teeth MetaADEDB
Sequestrectomy MetaADEDB
Seroma MetaADEDB
Shoulder Pain MetaADEDB
Sickle Cell Anaemia With Crisis MetaADEDB
Sinus Polyp MetaADEDB
Sinusitis ADReCS
Sjogren Syndrome MetaADEDB
Skin Fibrosis MetaADEDB
Skin Tightness MetaADEDB
Sleep Apnea MetaADEDB
Sleep Disorder ADReCS
Small Intestinal Obstruction MetaADEDB
Small Intestine Carcinoma MetaADEDB
Snoring MetaADEDB
Somnolence ADReCS
Speech Disorder MetaADEDB
Spinal Cord Compression MetaADEDB
Spinal Fusion Surgery MetaADEDB
Spinal Osteoarthritis MetaADEDB
Sputum Purulent MetaADEDB
Stent Occlusion MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stomach Discomfort ADReCS
Stridor MetaADEDB
Subileus MetaADEDB
Swollen Tongue MetaADEDB
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tardive Dyskinesia MetaADEDB
Temperature Intolerance MetaADEDB
Tendon Injury MetaADEDB
Tenosynovitis MetaADEDB
Tenosynovitis Stenosans MetaADEDB
Tension ADReCS
Therapeutic Response Unexpected MetaADEDB
Thirst ADReCS
Thoracic Cavity Drainage MetaADEDB
Thoracic Outlet Syndrome MetaADEDB
Thoracic Vertebral Fracture MetaADEDB
Throat Irritation ADReCS
Throat Tightness MetaADEDB
Thyroid Adenoma MetaADEDB
Thyroid Neoplasia MetaADEDB
Tinea Cruris MetaADEDB
Tooth Extraction MetaADEDB
Tooth Impacted MetaADEDB
Tri-Iodothyronine Increased MetaADEDB
Tuberculosis Gastrointestinal MetaADEDB
Tympanic Membrane Perforation MetaADEDB
Type Iv Hypersensitivity Reaction MetaADEDB
Upper Respiratory Tract Infection ADReCS
Upset Stomach SIDER
Urethritis MetaADEDB
Urinary Tract Disorder MetaADEDB
Urine Abnormality MetaADEDB
Urine Odour Abnormal MetaADEDB
Urosepsis MetaADEDB
Urticaria ADReCS
Venous Insufficiency MetaADEDB
Viral Infection ADReCS
Vision Blurred ADReCS
Vitamin A Deficiency MetaADEDB
Vitamin B 12 Deficiency MetaADEDB
Vitamin B12 Decreased MetaADEDB
Vitreous Haemorrhage MetaADEDB
Vocal Cord Polyp MetaADEDB
Vomiting ADReCS
Weight Gain MetaADEDB
Wheeze MetaADEDB
Wound Drainage MetaADEDB
Xanthelasma MetaADEDB
Xanthopsia MetaADEDB

InAADR: Drug-Protein-ADRs database