InAADR

Drug Information

Drug Name: Ezetimibe (163222-33-1)
PubChem ID: 150311
SMILES: C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O
InchiKey: OLNTVTPDXPETLC-XPWALMASSA-N
Therapeutic Category: Anticholesteremic Agents, Antimetabolites, Hypolipidemic Agents, Lipid Regulating Agents

Computed Drug Properties

Molecular Weight (dalton): 409.432
LogP: 4.8883
Ring Count: 3
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 60.77

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Mass MetaADEDB
Abdominal Pain ADReCS
Abdominal Wall Cyst MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Accelerated Hypertension MetaADEDB
Accidental Death MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acid Reflux MetaADEDB
Acquired Oesophageal Web MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Addison Disease MetaADEDB
Adenocarcinoma MetaADEDB
Administration Site Pain MetaADEDB
Adrenal Suppression MetaADEDB
Afib MetaADEDB
Ageusia MetaADEDB
Air Embolism MetaADEDB
Alanine Aminotransferase Increased ADReCS
Allergic Dermatitis MetaADEDB
Allergic Rhinitis MetaADEDB
Allergies MetaADEDB
Alopecia MetaADEDB
Alveolitis MetaADEDB
Amentia MetaADEDB
Amnesia MetaADEDB
Anaemia MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Androgen Deficiency MetaADEDB
Angina MetaADEDB
Angioedema ADReCS
Anticonvulsant Drug Level Above Therapeutic MetaADEDB
Antidepressant Drug Level Above Therapeutic MetaADEDB
Antinuclear Antibody MetaADEDB
Antipsychotic Drug Level Increased MetaADEDB
Antiviral Drug Level Above Therapeutic MetaADEDB
Anxiety MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Stenosis MetaADEDB
Apathy MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Apoplexy MetaADEDB
Application Site Erythema MetaADEDB
Application Site Scab MetaADEDB
Aptyalism MetaADEDB
Arrhythmia MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Arthritis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Asystole MetaADEDB
Ataxia MetaADEDB
Atelectasis MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Autonomic Instability MetaADEDB
Azotaemia MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Conjunctivitis MetaADEDB
Bacterial Toxaemia MetaADEDB
Barrett Oesophagus MetaADEDB
Biopsy Lymph Gland MetaADEDB
Bipolar Disorder MetaADEDB
Bipolar I Disorder MetaADEDB
Birth Defect MetaADEDB
Bladder Discomfort MetaADEDB
Bladder Disorder MetaADEDB
Bladder Retention MetaADEDB
Blepharoptosis MetaADEDB
Blood 125-Dihydroxycholecalciferol Decreased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Cholesterol Abnormal MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Disorder MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Glucose Fluctuation MetaADEDB
Blood In Urine MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Thrombin Abnormal MetaADEDB
Blood Thyroid Stimulating Hormone MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blurred Vision MetaADEDB
Bone Spur MetaADEDB
Bradypnoea MetaADEDB
Brain Oedema MetaADEDB
Breast Cellulitis MetaADEDB
Breath Sounds Abnormal MetaADEDB
Breath Sounds Absent MetaADEDB
Bronchitis MetaADEDB
Bruise MetaADEDB
Bulging MetaADEDB
Burn Oesophageal MetaADEDB
Caecitis MetaADEDB
Candida Infection MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carbon Monoxide Poisoning MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardiogenic Shock MetaADEDB
Carotid Artery Stenosis MetaADEDB
Cartilage Development Disorder MetaADEDB
Cataract MetaADEDB
Cataract Nuclear MetaADEDB
Cataract Operation MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cellulitis MetaADEDB
Cerebellar Ischaemia MetaADEDB
Cerebrovascular Accident Prophylaxis MetaADEDB
Cervicalgia MetaADEDB
Cervix Disorder MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Chill MetaADEDB
Cholangiolitis MetaADEDB
Cholecystectomy ADReCS
Cholecystitis ADReCS
Cholecystitis Infective MetaADEDB
Cholelithiasis ADReCS
Chronic Allograft Nephropathy MetaADEDB
Chronic Fatigue Syndrome MetaADEDB
Chronic Respiratory Failure MetaADEDB
Claustrophobia MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cognitive Disorder MetaADEDB
Colectomy MetaADEDB
Colonic Polyp MetaADEDB
Color Blindness MetaADEDB
Confabulation MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Conjunctival Deposit MetaADEDB
Connective Tissue Disorder SIDER
Cough ADReCS
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Dehydroepiandrosterone Increased MetaADEDB
Dehydroepiandrosterone Test MetaADEDB
Demyelination MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Device Malfunction MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Ulcer MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Difficult To Wean From Ventilator MetaADEDB
Disease Of Liver MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction SIDER
Dry Eye MetaADEDB
Dry Skin MetaADEDB
Dyslipidaemia MetaADEDB
Dysphonia MetaADEDB
Dysuria MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Ebv Infection MetaADEDB
Ecchymoses MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Economic Problem MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Poor R-Wave Progression MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Electrolyte Disorder MetaADEDB
Elevated Triglycerides MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Encephalitis MetaADEDB
Encephalopathy MetaADEDB
Endotracheal Intubation MetaADEDB
Enlarged Liver MetaADEDB
Enterococcal Infection MetaADEDB
Enterovesical Fistula MetaADEDB
Enzyme Abnormality MetaADEDB
Erectile Dysfunction MetaADEDB
Erosive Gastritis MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Erythema Migrans MetaADEDB
Erythema Multiforme ADReCS
Esophageal Rupture MetaADEDB
Excessive Sleepiness MetaADEDB
Extrasystoles Ventricular MetaADEDB
Extremity Pain MetaADEDB
Eye Infection MetaADEDB
Eye Pain MetaADEDB
Eye Pruritus MetaADEDB
Eye Swelling MetaADEDB
Face Injury MetaADEDB
Facial Flushing MetaADEDB
Factor V Inhibition MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fatty Stools MetaADEDB
Feeling Abnormal MetaADEDB
Femur Fracture MetaADEDB
Fibromyalgia MetaADEDB
Flank Pain MetaADEDB
Flatulence MetaADEDB
Foot Fracture MetaADEDB
Formication MetaADEDB
Fungal Disease MetaADEDB
Gallbladder Disorder ADReCS
Gallbladder Operation MetaADEDB
Gallop Rhythm Present MetaADEDB
Gambling MetaADEDB
Gamma-Glutamyltransferase Increased ADReCS
Gangrene MetaADEDB
Gastric Infection MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Generalised Erythema MetaADEDB
Giardiasis MetaADEDB
Gingival Disorder MetaADEDB
Gingival Pruritus MetaADEDB
Gouty Arthritis MetaADEDB
Granulocytosis MetaADEDB
Granuloma MetaADEDB
Haematoma MetaADEDB
Haematoma Infection MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Helicobacter Gastritis MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Enzyme Abnormal ADReCS
Hepatic Failure MetaADEDB
Hepatic Impairment ADReCS
Hepatic Necrosis MetaADEDB
Hepatitis ADReCS
Hepatotoxicity MetaADEDB
Hernia MetaADEDB
Hernia Repair MetaADEDB
High Blood Pressure MetaADEDB
Hip Fracture MetaADEDB
Homicidal Ideation MetaADEDB
Hot Flash MetaADEDB
Hungry Bone Syndrome MetaADEDB
Hyperhidrosis MetaADEDB
Hypermagnesaemia MetaADEDB
Hyperparathyroidism MetaADEDB
Hyperphosphataemia MetaADEDB
Hypersensitivity ADReCS
Hypertensive Emergency MetaADEDB
Hypertonia MetaADEDB
Hypertonic Bladder MetaADEDB
Hypertrichosis MetaADEDB
Hypoaesthesia MetaADEDB
Hypoglycaemic Unconsciousness MetaADEDB
Hypothalamo-Pituitary Disorder MetaADEDB
Hypoxia MetaADEDB
Infantile Spasms MetaADEDB
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Initial Insomnia MetaADEDB
Injection Site Erosion MetaADEDB
Injection Site Nodule MetaADEDB
Inner Ear Inflammation MetaADEDB
International Normalised Ratio MetaADEDB
International Normalised Ratio Decreased MetaADEDB
Intervertebral Disc Injury MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Ischias MetaADEDB
Itch MetaADEDB
Jaw Disorder MetaADEDB
Joint Stabilisation MetaADEDB
Kidney Failure MetaADEDB
Kidney Infection MetaADEDB
Laryngeal Disorder MetaADEDB
Left Atrial Dilatation MetaADEDB
Lethargy MetaADEDB
Lipase MetaADEDB
Liver Disorder ADReCS
Liver Transplant MetaADEDB
Loss Of Weight MetaADEDB
Lung Edema MetaADEDB
Lung Infection MetaADEDB
Lung Squamous Cell Carcinoma Stage Unspecified MetaADEDB
Malignant Hypertension MetaADEDB
Malnourished MetaADEDB
Marital Problem MetaADEDB
Medical Device Complication MetaADEDB
Meningioma Benign MetaADEDB
Mental Disorder Due To A General Medical Condition MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metabolic Syndrome MetaADEDB
Middle Insomnia MetaADEDB
Migraine MetaADEDB
Mitral Valve Calcification MetaADEDB
Mouth Pain MetaADEDB
Multiple Injuries MetaADEDB
Muscle Disorder MetaADEDB
Muscle Relaxant Drug Level Above Therapeutic MetaADEDB
Muscle Swelling MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder SIDER
Musculoskeletal Stiffness MetaADEDB
Myalgia ADReCS
Myasthenia Gravis MetaADEDB
Myopathy ADReCS
Nasal Discomfort MetaADEDB
Nasal Disorder MetaADEDB
Nasal Sinus Congestion MetaADEDB
Nasal Turbinate Hypertrophy MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Near Syncope MetaADEDB
Nephrogenic Anaemia MetaADEDB
Neumonia MetaADEDB
Neuralgia MetaADEDB
Neuroendocrine Carcinoma Of The Skin MetaADEDB
Neutropenic Colitis MetaADEDB
Nocturnal Dyspnoea MetaADEDB
Oral Fungal Infection MetaADEDB
Oral Mucosal Exfoliation MetaADEDB
Oral Surgery MetaADEDB
Osteoarthropathy SIDER
Osteopenia MetaADEDB
Pain ADReCS
Pain In Arm ADReCS
Pain In Extremity ADReCS
Pain Pelvic MetaADEDB
Palpitations ADReCS
Pancreatitis ADReCS
Panniculitis ADReCS
Paraesthesia ADReCS
Parathyroid Tumour Benign MetaADEDB
Peripheral Embolism MetaADEDB
Peripheral Ischaemia MetaADEDB
Personality Disorder MetaADEDB
Pharyngeal Lesion MetaADEDB
Pharyngitis ADReCS
Pharyngolaryngeal Pain MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Post Procedural Haematoma MetaADEDB
Postoperative Ileus MetaADEDB
Potentiating Drug Interaction MetaADEDB
Productive Cough MetaADEDB
Prostatic Disorder MetaADEDB
Pseudoporphyria MetaADEDB
Rash ADReCS
Renal Tubular Necrosis MetaADEDB
Respiration Abnormal MetaADEDB
Respiratory Disorder ADReCS
Respiratory Failure MetaADEDB
Respiratory Tract Infection ADReCS
Retinal Vascular Thrombosis MetaADEDB
Retroperitoneal Haematoma MetaADEDB
Rhabdomyolysis ADReCS
Rib Fracture MetaADEDB
Schizoaffective Disorder MetaADEDB
Self-Injurious Ideation MetaADEDB
Sensation Of Heaviness MetaADEDB
Sensory Disturbance MetaADEDB
Serratia Bacteraemia MetaADEDB
Serratia Infection MetaADEDB
Serum Ferritin Increased MetaADEDB
Serum Serotonin Decreased MetaADEDB
Sexual Relationship Change MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sinusitis ADReCS
Skin Lesion MetaADEDB
Sleep Apnea MetaADEDB
Sleep Disorder MetaADEDB
Small Intestinal Obstruction MetaADEDB
Social Avoidant Behaviour ADReCS
Spinning Sensation MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stress MetaADEDB
Subclavian Artery Thrombosis MetaADEDB
Sudden Cardiac Death MetaADEDB
Superficial Thrombophlebitis MetaADEDB
Supraventricular Tachycardia MetaADEDB
Swollen Tongue MetaADEDB
Temperature Intolerance MetaADEDB
Temporal Arteritis MetaADEDB
Thrombocytopenia ADReCS
Thyroid Disease MetaADEDB
Thyroid Function Test MetaADEDB
Thyroid Neoplasia MetaADEDB
Tinnitus MetaADEDB
Tongue Disorder MetaADEDB
Tonsillitis MetaADEDB
Tooth Infection MetaADEDB
Tracheal Pain MetaADEDB
Transaminases Increased ADReCS
Transient Ischaemic Attack MetaADEDB
Traumatic Shock MetaADEDB
Troponin I Increased MetaADEDB
Tubulointerstitial Nephritis MetaADEDB
Unevaluable Event MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Limb Fracture MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urine Arsenic Increased MetaADEDB
Urine Flow Decreased MetaADEDB
Urticaria ADReCS
Vascular Pseudoaneurysm MetaADEDB
Vasomotor Rhinitis MetaADEDB
Viral Infection ADReCS
Visual Disturbance MetaADEDB
Vitrectomy MetaADEDB
Vulvovaginal Mycotic Infection MetaADEDB
Walking Disability MetaADEDB
Weight Gain MetaADEDB
Withdrawn SIDER
Wound Drainage MetaADEDB

InAADR: Drug-Protein-ADRs database