InAADR

Drug Information

Drug Name: Everolimus (159351-69-6)
PubChem ID: 122362259
SMILES: [2H]C([2H])(C([2H])([2H])O[C@@H]1CC[C@H](C[C@H]1OC)C[C@@H](C)[C@@H]2CC(=O)[C@@H](C=C([C@H]([C@H](C(=O)[C@@H](C[C@@H](/C=C/C=CC=C([C@H](C[C@@H]3CC[C@H]([C@@](O3)(C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)O)C)OC)C)C)C)OC)O)C)C)O
InchiKey: HKVAMNSJSFKALM-HWRCCPKDSA-N
Therapeutic Category: Antineoplastic Agents, Immunologic Factors, Immunosuppressive Agents

Computed Drug Properties

Molecular Weight (dalton): 962.264
LogP: 6.1972
Ring Count: 0
Hydrogen Bond Acceptor Count: 14
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 204.66

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Pain ADReCS
Abnormal Weight Gain MetaADEDB
Abscess MetaADEDB
Acne ADReCS
Actinic Keratosis MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome PROTECT
Acute Respiratory Failure ADReCS
Adrenal Neoplasm MetaADEDB
Ageusia PROTECT
Aggression PROTECT
Agitation PROTECT
Alanine Aminotransferase Increased ADReCS
Alopecia PROTECT
Alternaria Infection MetaADEDB
Alveolitis PROTECT
Amenorrhoea PROTECT
Anaemia ADReCS
Anal Fistula MetaADEDB
Angioedema PROTECT
Anorexia ADReCS
Anuria MetaADEDB
Anxiety ADReCS
Aphthous Stomatitis PROTECT
Aplasia Pure Red Cell PROTECT
Arthralgia PROTECT
Aspartate Aminotransferase Increased ADReCS
Aspergillosis ADReCS
Aspergillus Infection PROTECT
Aspiration ADReCS
Asthenia ADReCS
Bladder Cancer MetaADEDB
Blood Amylase MetaADEDB
Blood Bilirubin Increased ADReCS
Blood Calcium MetaADEDB
Blood Cholesterol Increased ADReCS
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased ADReCS
Blood Glucose Increased ADReCS
Blood Immunoglobulin G Decreased ADReCS
Blood Lactate Dehydrogenase Increased PROTECT
Blood Luteinising Hormone Increased PROTECT
Blood Phosphorus Decreased ADReCS
Blood Potassium Increased MetaADEDB
Blood Product Transfusion Dependent MetaADEDB
Blood Triglycerides Increased ADReCS
Body Tinea ADReCS
Bronchitis ADReCS
Bronchoalveolar Lavage MetaADEDB
Burning Sensation MetaADEDB
Candida Infection PROTECT
Candida Sepsis MetaADEDB
Candidiasis ADReCS
Carbohydrate Antigen 15-3 MetaADEDB
Cardiac Failure PROTECT
Cardiac Failure Acute MetaADEDB
Cardiac Failure Congestive ADReCS
Cardiac Ischemia MetaADEDB
Cellulitis ADReCS
Chest Pain ADReCS
Chest X-Ray Abnormal ADReCS
Chills ADReCS
Chronic Allograft Nephropathy MetaADEDB
Citrobacter Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cmv Infection MetaADEDB
Colitis Ischaemic MetaADEDB
Complement Factor C3 Decreased MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Convulsion ADReCS
Cough ADReCS
Cyclic Neutropenia ADReCS
Decreased Appetite PROTECT
Deep Vein Thrombosis PROTECT
Dehydration ADReCS
Dermatitis Acneiform ADReCS
Dermatitis Contact ADReCS
Dermatitis Medicamentosa MetaADEDB
Dermatitis Seborrheic MetaADEDB
Diabetes Mellitus ADReCS
Diarrhoea ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Interaction MetaADEDB
Dry Mouth ADReCS
Dry Skin ADReCS
Dysgeusia ADReCS
Dyspepsia PROTECT
Dysphagia ADReCS
Dyspnoea ADReCS
Enterobacter Infection MetaADEDB
Enterovesical Fistula MetaADEDB
Epidural Lipomatosis MetaADEDB
Epistaxis ADReCS
Eruption MetaADEDB
Erythema ADReCS
Escherichia Sepsis MetaADEDB
Excoriation ADReCS
Eyelid Oedema ADReCS
Fatigue ADReCS
Fistula MetaADEDB
Flatulence PROTECT
Flushing PROTECT
Gait Disturbance PROTECT
Gastric Infection ADReCS
Gastritis ADReCS
Gastroenteritis ADReCS
Gingival Pain PROTECT
Gingivitis PROTECT
Glomerular Filtration Rate Decreased MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephropathy MetaADEDB
Glossitis PROTECT
Graft Dysfunction MetaADEDB
Graft Loss MetaADEDB
Haemoglobin Decreased ADReCS
Haemoptysis PROTECT
Haemorrhage ADReCS
Haemorrhage Rectum MetaADEDB
Haemorrhagic Anaemia MetaADEDB
Haemorrhoids ADReCS
Headache ADReCS
Hepatitis B PROTECT
Herpes Zoster PROTECT
High Blood Pressure MetaADEDB
Human Herpesvirus 8 Infection MetaADEDB
Hypercholesterolaemia ADReCS
Hyperglycaemia ADReCS
Hyperlipidaemia PROTECT
Hypersensitivity PROTECT
Hypertension ADReCS
Hypertonia MetaADEDB
Hypertrichosis MetaADEDB
Hypertriglyceridaemia ADReCS
Hypocalcaemia PROTECT
Hypoglycaemic Seizure MetaADEDB
Hypokalaemia PROTECT
Hypomagnesaemia MetaADEDB
Hypophosphataemia ADReCS
Hypotension Orthostatic MetaADEDB
Hypoxia MetaADEDB
Impaired Healing ADReCS
Implantable Defibrillator Insertion MetaADEDB
Infection ADReCS
Infestation PROTECT
Insomnia ADReCS
Interstitial Lung Disease PROTECT
Irritability PROTECT
Ischaemic Cerebral Infarction MetaADEDB
Ischaemic Stroke MetaADEDB
Leukocyturia MetaADEDB
Leukopenia PROTECT
Lip Ulceration PROTECT
Lipase MetaADEDB
Lung Edema MetaADEDB
Lung Infiltration PROTECT
Lymphocyte Count Decreased ADReCS
Lymphopenia ADReCS
Malignant Ascites MetaADEDB
Menorrhagia PROTECT
Menstruation Delayed PROTECT
Menstruation Irregular PROTECT
Mononeuritis MetaADEDB
Mouth Ulceration PROTECT
Mucosal Inflammation ADReCS
Muscle Necrosis MetaADEDB
Nail Disorder ADReCS
Nasal Congestion ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Nephrogenic Anaemia MetaADEDB
Nephrostomy MetaADEDB
Neuromuscular Disorder MetaADEDB
Neutropenia PROTECT
Neutrophil Count Decreased ADReCS
Ocular Hyperaemia ADReCS
Odynophagia MetaADEDB
Oedema Peripheral PROTECT
Oliguria MetaADEDB
Onychoclasis ADReCS
Opportunistic Infection PROTECT
Oral Herpes MetaADEDB
Oropharyngeal Pain ADReCS
Otitis Externa ADReCS
Otitis Media ADReCS
Ovarian Cyst PROTECT
Pain In Extremity ADReCS
Pain In Jaw ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome ADReCS
Palpitation MetaADEDB
Papilloma Viral Infection MetaADEDB
Paraesthesia ADReCS
Percutaneous Coronary Intervention MetaADEDB
Perianal Abscess MetaADEDB
Periorbital Oedema ADReCS
Perirectal Abscess MetaADEDB
Perirenal Haematoma MetaADEDB
Personality Change ADReCS
Pharyngeal Inflammation ADReCS
Pharyngitis ADReCS
Pityriasis MetaADEDB
Platelet Count Decreased ADReCS
Pleural Effusion ADReCS
Pneumatic Compression Therapy MetaADEDB
Pneumonia ADReCS
Pneumonitis ADReCS
Postrenal Failure MetaADEDB
Proteinuria ADReCS
Pruritus ADReCS
Pulmonary Alveolar Haemorrhage PROTECT
Pulmonary Embolism PROTECT
Pulmonary Toxicity PROTECT
Pyrexia ADReCS
Pyuria MetaADEDB
Rash ADReCS
Rash Erythematous PROTECT
Rash Generalised PROTECT
Rash Macular PROTECT
Rash Maculo-Papular PROTECT
Renal Failure ADReCS
Renal Failure Acute ADReCS
Rhabdomyolysis PROTECT
Rhinitis Allergic ADReCS
Rhinorrhoea ADReCS
Sepsis ADReCS
Sinusitis ADReCS
Skin Exfoliation PROTECT
Skin Infection ADReCS
Skin Lesion ADReCS
Sleep Apnoea Syndrome ADReCS
Small Intestinal Obstruction MetaADEDB
Soft Tissue Infection MetaADEDB
Somnolence ADReCS
Spindle Cell Sarcoma MetaADEDB
Squamous Cell Carcinoma Of Skin MetaADEDB
Stomatitis ADReCS
Sudden Death MetaADEDB
Synovitis MetaADEDB
Tachycardia ADReCS
Thrombocytopenia PROTECT
Thrombotic Microangiopathy MetaADEDB
Tongue Ulceration PROTECT
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Vaginal Haemorrhage PROTECT
Vesicoureteral Reflux Surgery MetaADEDB
Vomiting ADReCS
Weight Decreased ADReCS
White Blood Cell Count Decreased ADReCS
Wrist Fracture MetaADEDB

InAADR: Drug-Protein-ADRs database