InAADR

Drug Information

Drug Name: Ethosuximide (77-67-8)
PubChem ID: 3291
SMILES: CCC1(CC(=O)NC1=O)C
InchiKey: HAPOVYFOVVWLRS-UHFFFAOYSA-N
Therapeutic Category: Anticonvulsants, Central Nervous System Agents

Computed Drug Properties

Molecular Weight (dalton): 141.17
LogP: 0.4492
Ring Count: 0
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 46.17

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Isoniazid (54-85-3) Insomnia Synergistic isoniazid may have inhibited the metabolism of the ethosuximide Ethosuximide intoxication caused by interaction with isoniazid

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abdominal Wall Cyst MetaADEDB
Abnormal Eeg MetaADEDB
Aching Joints MetaADEDB
Adrenal Neoplasm MetaADEDB
Aggression ADReCS
Agitation ADReCS
Agranulocytosis ADReCS
Akathisia Drug-Induced MetaADEDB
Allergic Reaction ADReCS
Ammonia Increased MetaADEDB
Anal Atresia MetaADEDB
Anemia Aplastic MetaADEDB
Angioedema MetaADEDB
Anhidrosis MetaADEDB
Anorexia ADReCS
Apathy MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arthralgia MetaADEDB
Asthenia ADReCS
Ataxia ADReCS
Atonic Seizures MetaADEDB
Automatism MetaADEDB
Birth Defect MetaADEDB
Bleb MetaADEDB
Bleeding Vaginal SIDER
Blepharospasm MetaADEDB
Blood Pressure Abnormal MetaADEDB
Body Dysmorphic Disorder MetaADEDB
Bone Fracture MetaADEDB
Bradycardia MetaADEDB
Brain Oedema MetaADEDB
Brain Stem Syndrome MetaADEDB
Carnitine Decreased MetaADEDB
Causalgia MetaADEDB
Cerebellar Atrophy MetaADEDB
Cerebral Artery Stenosis MetaADEDB
Cerebration Impaired SIDER
Chest Infection MetaADEDB
Complex Partial Seizures MetaADEDB
Complicated Fracture MetaADEDB
Congenital Heart Disease MetaADEDB
Congenital Vesicoureteric Reflux MetaADEDB
Coordination Abnormal MetaADEDB
Cramp Muscle SIDER
Csf Pressure Decreased MetaADEDB
Csf Protein Increased MetaADEDB
Decreased Appetite ADReCS
Depressed Level Of Consciousness MetaADEDB
Dermatitis ADReCS
Dermatosis MetaADEDB
Dermographism MetaADEDB
Diarrhoea ADReCS
Disinhibition MetaADEDB
Dislocation MetaADEDB
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Addict MetaADEDB
Drug Eruption ADReCS
Drug Ineffective MetaADEDB
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Dupuytren Contracture MetaADEDB
Dyskinesia Drug-Induced MetaADEDB
Dyskinesias MetaADEDB
Educational Problem MetaADEDB
Emotional Distress ADReCS
Eosinophilia ADReCS
Epilepsies Partial MetaADEDB
Epilepsy MetaADEDB
Epilepsy Absence MetaADEDB
Epilepsy Tonic-Clonic MetaADEDB
Epiphyses Delayed Fusion MetaADEDB
Euphoric Mood ADReCS
Failure To Thrive MetaADEDB
Fatigue ADReCS
Feeling Abnormal MetaADEDB
Fever MetaADEDB
Formication MetaADEDB
Fractured Pelvis Nos MetaADEDB
Gastric Disorder ADReCS
Gastrointestinal Disorder ADReCS
Gastrointestinal Pain ADReCS
Gastrointestinal Symptom Nos SIDER
Generalised Anxiety Disorder MetaADEDB
Gingival Hypertrophy ADReCS
Haemangioma MetaADEDB
Haematuria ADReCS
Haemoglobin ADReCS
Haemorrhage ADReCS
Hand Fracture MetaADEDB
Headache ADReCS
Hematuria MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Trauma MetaADEDB
Hepatotoxicity MetaADEDB
Hernia MetaADEDB
Hernia Inguinal MetaADEDB
Hiccough MetaADEDB
Hiccups ADReCS
Hirsutism ADReCS
Hiv Disease MetaADEDB
Hydrocele MetaADEDB
Hydronephrosis MetaADEDB
Hyperalgesia MetaADEDB
Hyperammonaemia MetaADEDB
Hyperkinesia ADReCS
Hypersensitivity ADReCS
Hypertrophy ADReCS
Hypospadias MetaADEDB
Hypoxia MetaADEDB
Impaired Driving Ability MetaADEDB
Impaired Work Ability MetaADEDB
Inappropriate Affect MetaADEDB
Incorrect Dose Administered MetaADEDB
Intestinal Malrotation MetaADEDB
Irritability ADReCS
Joint Injury MetaADEDB
Kidney Diseases MetaADEDB
Klebsiella Infection MetaADEDB
Lactose Intolerance MetaADEDB
Lethargy ADReCS
Leukopenia ADReCS
Libido Increased ADReCS
Liver Diseases MetaADEDB
Lupus Erythematosus SIDER
Lupus Erythematosus Systemic MetaADEDB
Lymphopenia MetaADEDB
Macroglossia MetaADEDB
Mania MetaADEDB
Mental Disability ADReCS
Microscopic Hematuria SIDER
Migraine MetaADEDB
Mood Altered MetaADEDB
Mucosal Haemorrhage MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Myopia ADReCS
Nausea ADReCS
Nephrotic Syndrome MetaADEDB
Nerve Degeneration MetaADEDB
Nervous Tension MetaADEDB
Oculocephalogyric Reflex Absent MetaADEDB
Osteolysis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Pain ADReCS
Pancytopenia ADReCS
Paranoia ADReCS
Parkinson Disease Secondary MetaADEDB
Patent Ductus Arteriosis MetaADEDB
Personality Disorders MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Phimosis MetaADEDB
Plagiocephaly MetaADEDB
Pollakiuria MetaADEDB
Poor Quality Drug Administered MetaADEDB
Pre-Eclampsia MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Pressure Of Speech MetaADEDB
Priapism MetaADEDB
Proteinuria MetaADEDB
Pseudo Lymphoma MetaADEDB
Psychomotor Hyperactivity ADReCS
Psychotic Disorder ADReCS
Pyloric Stenosis MetaADEDB
Rash ADReCS
Rash Erythematous ADReCS
Reye Syndrome MetaADEDB
Seizures MetaADEDB
Sleep Disorder ADReCS
Sleep Terror ADReCS
Somnolence ADReCS
Spinning Sensation MetaADEDB
Stent Occlusion MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stridor MetaADEDB
Swelling ADReCS
Swollen Tongue ADReCS
Systemic Lupus Erythematosus ADReCS
Thoracic Vertebral Fracture MetaADEDB
Thrombocytopenia MetaADEDB
Tracheo-Oesophageal Fistula MetaADEDB
Tremor MetaADEDB
Upset Stomach SIDER
Urine Flow Decreased MetaADEDB
Urticaria ADReCS
Vaginal Haemorrhage ADReCS
Vomiting ADReCS
Weight Decreased ADReCS
Weight Loss MetaADEDB

InAADR: Drug-Protein-ADRs database