InAADR

Drug Information

Drug Name: Epoprostenol (35121-78-9)
PubChem ID: 5462154
SMILES: CCCCCC(/C=C/C1C(CC2C1C/C(=C/CCCC(=O)O)/O2)O)O
InchiKey: KAQKFAOMNZTLHT-FHZLGBCPSA-N
Therapeutic Category: Antihypertensive Agents, Cardiovascular Agents, Hematologic Agents, Platelet Aggregation Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 352.471
LogP: 3.4085
Ring Count: 0
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 86.99

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abnormal Vision ADReCS
Abortion Induced MetaADEDB
Accident MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Coronary Syndrome ADReCS
Adenopathy MetaADEDB
Adverse Event MetaADEDB
Agitation ADReCS
Alanine Aminotransferase Increased ADReCS
Albuminuria ADReCS
Alcohol Intolerance ADReCS
Allergic Dermatitis MetaADEDB
Allergic Vasculitis MetaADEDB
Alopecia MetaADEDB
Amblyopia ADReCS
Anaemia ADReCS
Anaemia Hypochromic MetaADEDB
Angina Pectoris ADReCS
Angiopathy ADReCS
Anorexia ADReCS
Anti-Neutrophil Cytoplasmic Antibody Positive Vasculitis MetaADEDB
Anti-Platelet Antibody MetaADEDB
Anxiety ADReCS
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Arrhythmia ADReCS
Arthralgia ADReCS
Arthritis ADReCS
Ascites ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Asthma ADReCS
Asystole MetaADEDB
Ataxia ADReCS
Atrial Fibrillation ADReCS
Autoimmune Disorder MetaADEDB
Autoimmune Thyroiditis MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Basedow Disease MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Dilatation MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bleeding Vaginal MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Blister MetaADEDB
Blood Calcium MetaADEDB
Blood Corticotrophin MetaADEDB
Blood Cortisol Decreased MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Platelet Disorders MetaADEDB
Blood Thyroid Stimulating Hormone MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Failure MetaADEDB
Bone Pain ADReCS
Bradycardia ADReCS
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Burn Oesophageal MetaADEDB
Caesarean Section MetaADEDB
Candida Infection MetaADEDB
Cardiac Aneurysm MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure High Output MetaADEDB
Cardiac Index Decreased MetaADEDB
Cardiac Septal Defect MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Diseases MetaADEDB
Catalepsy MetaADEDB
Catheter Placement MetaADEDB
Catheter Related Complication MetaADEDB
Catheter Related Infection MetaADEDB
Catheter Removal MetaADEDB
Catheter Sepsis MetaADEDB
Catheter Site Erythema MetaADEDB
Catheter Site Haemorrhage MetaADEDB
Catheter Site Infection MetaADEDB
Catheter Site Oedema MetaADEDB
Catheter Site Pain MetaADEDB
Catheter Site Related Reaction MetaADEDB
Catheterisation Cardiac MetaADEDB
Central Line Infection MetaADEDB
Cerebrovascular Accident ADReCS
Chest Pain ADReCS
Chest X-Ray Abnormal MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Chorioretinal Disorder MetaADEDB
Clotting MetaADEDB
Coagulation Test Abnormal MetaADEDB
Colic MetaADEDB
Colitis MetaADEDB
Collagen Disorder ADReCS
Colon Neoplasm MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Congenital Hydrocephalus MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Contact Dermatitis MetaADEDB
Convulsion ADReCS
Coronary Thrombosis MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Coughing Blood MetaADEDB
Cramp Muscle SIDER
Cramps Leg ADReCS
Cramps Of Lower Extremities SIDER
Crying MetaADEDB
Cyanosis ADReCS
Cystitis ADReCS
Decreased Activity MetaADEDB
Decreased Appetite ADReCS
Depression ADReCS
Depressive Disorder MetaADEDB
Depressive Type Psychosis SIDER
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Medicamentosa MetaADEDB
Device Connection Issue MetaADEDB
Device Failure MetaADEDB
Device Related Infection MetaADEDB
Diabetes Mellitus ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disease Progression MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Dizziness ADReCS
Drug Administration Error MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Mouth ADReCS
Duodenal Perforation MetaADEDB
Dysmorphism MetaADEDB
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dyspnoea At Rest MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Eczema ADReCS
Effusion ADReCS
Electrocardiogram Abnormal ADReCS
Electrolyte Disorder MetaADEDB
Embolism ADReCS
Emesis MetaADEDB
Emotional Disorder MetaADEDB
Encephalopathy MetaADEDB
Endometrial Atrophy MetaADEDB
Endometrial Hyperplasia MetaADEDB
Endotracheal Intubation Complication MetaADEDB
Enlarged Liver MetaADEDB
Enlarged Spleen MetaADEDB
Enlargement Abdomen SIDER
Enteritis Infectious MetaADEDB
Enterobacter Pneumonia MetaADEDB
Eosinophil Count Abnormal MetaADEDB
Eosinophil Count Increased MetaADEDB
Ephelides MetaADEDB
Epidural Hematoma MetaADEDB
Epistaxis ADReCS
Eruption MetaADEDB
Erythema MetaADEDB
Esophageal Rupture MetaADEDB
Esophageal Ulcer MetaADEDB
Extrapyramidal Disorder MetaADEDB
Extrasystoles ADReCS
Eye Swelling MetaADEDB
Eyelid Retraction MetaADEDB
Facial Flushing MetaADEDB
Familial Mediterranean Fever MetaADEDB
Fatigue ADReCS
Feeling Abnormal ADReCS
Fibroids MetaADEDB
Flatulence ADReCS
Flooding MetaADEDB
Flushing ADReCS
Foetal Warfarin Syndrome MetaADEDB
Food Interaction MetaADEDB
Food Poisoning MetaADEDB
Foreign Body Aspiration MetaADEDB
Furuncle ADReCS
Gallbladder Polyp MetaADEDB
Gastric Ulcer MetaADEDB
Gastritis ADReCS
Gastroenteritis ADReCS
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Genital Haemorrhage MetaADEDB
Genital Pruritus Female MetaADEDB
Genital Swelling ADReCS
Gingivitis ADReCS
Globulins Increased MetaADEDB
Glycosuria ADReCS
Goiter MetaADEDB
Gout ADReCS
Haematemesis MetaADEDB
Haematuria ADReCS
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhagic Anaemia MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Hair Growth Abnormal MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Heart Septal Defects Atrial MetaADEDB
Heart-Lung Transplant Rejection MetaADEDB
Helicobacter Infection MetaADEDB
Hematoma Subdural MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal MetaADEDB
Hepatic Lesion MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Simplex ADReCS
Hot Flashes MetaADEDB
Hot Flush ADReCS
Hyperaesthesia ADReCS
Hyperalgesia MetaADEDB
Hypercalcaemia ADReCS
Hypercholesterolaemia ADReCS
Hypergammaglobulinaemia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hyperkinesia ADReCS
Hyperkinesis MetaADEDB
Hypersplenism ADReCS
Hypertension MetaADEDB
Hypertension Pulmonary MetaADEDB
Hyperthyroidism ADReCS
Hypertriglyceridaemia ADReCS
Hypertrophy ADReCS
Hypoaesthesia ADReCS
Hypoalbuminaemia MetaADEDB
Hypogeusia MetaADEDB
Hypokalaemia ADReCS
Hyponatraemia ADReCS
Hypopituitarism MetaADEDB
Hypotension ADReCS
Hypothermia MetaADEDB
Hypoxia ADReCS
Idiopathic Thrombocytopenic Purpura MetaADEDB
Ild MetaADEDB
Implant Site Infection MetaADEDB
Incisional Hernia Obstructive MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Inflammatory Bowel Disease MetaADEDB
Influenza ADReCS
Influenza Like Illness ADReCS
Infusion Site Extravasation MetaADEDB
Injection Site Pain ADReCS
Injury ADReCS
Injury Asphyxiation MetaADEDB
Insomnia ADReCS
International Normalised Ratio Decreased MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Intussusception MetaADEDB
Irregular Menstrual Cycle MetaADEDB
Irritation Skin MetaADEDB
Ischaemia ADReCS
Ischemia MetaADEDB
Isolated Adrenocorticotropic Hormone Deficiency MetaADEDB
Leg Cramps ADReCS
Live Birth MetaADEDB
Liver Failure Acute MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lung Consolidation MetaADEDB
Lung Edema MetaADEDB
Lung Transplant MetaADEDB
Major Depression ADReCS
Malaise ADReCS
Medical Device Complication MetaADEDB
Micrococcal Sepsis MetaADEDB
Micrococcus Infection MetaADEDB
Migraine ADReCS
Mood Altered MetaADEDB
Morphea MetaADEDB
Multiple Sclerosis MetaADEDB
Muscle Spasms ADReCS
Muscle Tightness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Mycobacterium Avium Complex Infection MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Myocardial Ischemia MetaADEDB
Nasal Congestion MetaADEDB
Nausea ADReCS
Neck Pain ADReCS
Necrosis MetaADEDB
Neonatal Respiratory Distress Syndrome MetaADEDB
Neoplasms MetaADEDB
Nephrolithiasis ADReCS
Nephrotic Syndrome MetaADEDB
Nervousness ADReCS
Neuritis ADReCS
Nonspecific Reaction MetaADEDB
Oedema ADReCS
Oedema Genital ADReCS
Oedema Peripheral ADReCS
Oesophageal Disorder ADReCS
Oesophageal Hypomotility MetaADEDB
Oesophagitis ADReCS
Oliguria MetaADEDB
Oral Soft Tissue Disorder MetaADEDB
Oropharyngeal Blistering MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Otitis Externa ADReCS
Otitis Media ADReCS
Oxygen Saturation Decreased MetaADEDB
Oxygen Saturation Increased MetaADEDB
Oxygen Supplementation MetaADEDB
Pain ADReCS
Pain During Injection SIDER
Pain In Jaw ADReCS
Pallor ADReCS
Palpable Purpura MetaADEDB
Palpitation MetaADEDB
Palpitations ADReCS
Pancytopenia ADReCS
Paradoxical Embolism MetaADEDB
Paraesthesia ADReCS
Patent Ductus Arteriosis MetaADEDB
Pelvic Haematoma MetaADEDB
Periodontitis ADReCS
Peripheral Ischaemia ADReCS
Peripheral Vascular Disorder ADReCS
Pharmaceutical Product Complaint MetaADEDB
Pharyngitis ADReCS
Phlebothrombosis MetaADEDB
Plasmapheresis MetaADEDB
Platelet Count MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pneumonia ADReCS
Pneumonia Viral MetaADEDB
Pneumothorax ADReCS
Pollakiuria ADReCS
Polyuria ADReCS
Portal Hypertension MetaADEDB
Premature Baby MetaADEDB
Productive Cough MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Time MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Psoriasis MetaADEDB
Psychomotor Agitation MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Arterial Hypertension MetaADEDB
Pulmonary Arterial Pressure Increased MetaADEDB
Pulmonary Arterial Wedge Pressure Increased MetaADEDB
Pulmonary Artery Aneurysm MetaADEDB
Pulmonary Artery Wall Hypertrophy MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Embolism ADReCS
Pulmonary Eosinophilia MetaADEDB
Pulmonary Oedema ADReCS
Pulmonary Vein Occlusion MetaADEDB
Pulmonary Vein Stenosis MetaADEDB
Pulmonary Veno-Occlusive Disease MetaADEDB
Purpura ADReCS
Pyrexia ADReCS
Rash ADReCS
Rash Maculo-Papular ADReCS
Raynaud Disease MetaADEDB
Rectal Haemorrhage ADReCS
Respiration Abnormal MetaADEDB
Respiratory Disorder ADReCS
Respiratory Syncytial Virus Bronchiolitis MetaADEDB
Retinal Bleeding MetaADEDB
Retinal Exudates MetaADEDB
Retinopathy Of Prematurity MetaADEDB
Rhinitis ADReCS
Rhinorrhea MetaADEDB
Right Heart Failure MetaADEDB
Right Ventricular Failure ADReCS
Right Ventricular Hypertrophy MetaADEDB
Right Ventricular Systolic Pressure Increased MetaADEDB
Sepsis ADReCS
Septic Embolus MetaADEDB
Serratia Infection MetaADEDB
Shock ADReCS
Shock Septic MetaADEDB
Sinusitis ADReCS
Skin Bacterial Infection MetaADEDB
Skin Infection ADReCS
Skin Lesion MetaADEDB
Skin Ulcer ADReCS
Somnolence ADReCS
Splenomegaly ADReCS
Staphylococcal Infection MetaADEDB
Stereotypic Movement Disorder MetaADEDB
Stress MetaADEDB
Stroke MetaADEDB
Subileus MetaADEDB
Sudden Death MetaADEDB
Supraventricular Tachycardia ADReCS
Sweating SIDER
Syncope ADReCS
Systemic Candida MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Temperature Regulation Disorder MetaADEDB
Tendonitis ADReCS
Tension ADReCS
Therapeutic Response Decreased MetaADEDB
Therapy Cessation MetaADEDB
Therapy Non-Responder MetaADEDB
Thirst ADReCS
Thrombocytopenia ADReCS
Thromboembolism MetaADEDB
Thrombosis MetaADEDB
Thrombotic Microangiopathy MetaADEDB
Thyroid Disease MetaADEDB
Thyroid Function Test MetaADEDB
Thyroiditis MetaADEDB
Tinnitus ADReCS
Toothache ADReCS
Tremor ADReCS
Tri-Iodothyronine Increased MetaADEDB
Ulcer ADReCS
Upper Respiratory Tract Infection ADReCS
Urinary Incontinence ADReCS
Urinary Tract Infection ADReCS
Urticaria ADReCS
Vagus Nerve Disorder MetaADEDB
Vasculitic Rash MetaADEDB
Vasodilation SIDER
Vasodilation Procedure ADReCS
Vasospasm Intracranial MetaADEDB
Ventricular Dysfunction Left MetaADEDB
Ventricular Failure ADReCS
Vertigo ADReCS
Vessel Puncture Site Haematoma MetaADEDB
Viral Infection ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS
Xerophthalmia ADReCS

InAADR: Drug-Protein-ADRs database