InAADR

Drug Information

Drug Name: Dutasteride (164656-23-9)
PubChem ID: 6918296
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@@H]5[C@@]3(C=CC(=O)N5)C
InchiKey: JWJOTENAMICLJG-QWBYCMEYSA-N
Therapeutic Category: 5-alpha Reductase Inhibitors, Enzyme Inhibitors, Hormone Antagonists, Hormones, Urological Agents

Computed Drug Properties

Molecular Weight (dalton): 528.537
LogP: 6.5761
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 58.2

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Mass MetaADEDB
Abdominal Symptom MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Loss Of Weight MetaADEDB
Abscess Drainage MetaADEDB
Abscess Management MetaADEDB
Accelerated Hypertension MetaADEDB
Accidental Exposure MetaADEDB
Acid Reflux MetaADEDB
Acne Rosacea MetaADEDB
Acquired Oesophageal Web MetaADEDB
Acute Febrile Neutrophilic Dermatosis MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Adenoma Benign ADReCS
Adenopathy MetaADEDB
Afib MetaADEDB
Alanine Aminotransferase Abnormal MetaADEDB
Alopecia MetaADEDB
Alpha-1 Anti-Trypsin Increased MetaADEDB
Als MetaADEDB
Alveoloplasty MetaADEDB
Amentia MetaADEDB
Amyotrophy MetaADEDB
Anaemia Of Chronic Disease MetaADEDB
Anaemia Postoperative MetaADEDB
Anal Fistula MetaADEDB
Angioedema ADReCS
Angiogram Abnormal MetaADEDB
Angiopathy MetaADEDB
Anhedonia MetaADEDB
Anhidrosis MetaADEDB
Ankle Brachial Index Decreased MetaADEDB
Ankyloglossia Acquired MetaADEDB
Anorectal Discomfort MetaADEDB
Aortic Calcification MetaADEDB
Aortic Disorder MetaADEDB
Aphagia MetaADEDB
Aphonia MetaADEDB
Aptyalism MetaADEDB
Arthritis MetaADEDB
Aspartate Aminotransferase Abnormal MetaADEDB
Asthenopia MetaADEDB
Atelectasis MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Atrophy MetaADEDB
Atrophy Of Skin MetaADEDB
Autologous Bone Marrow Transplantation Therapy MetaADEDB
Autonomic Instability MetaADEDB
B-Cell Lymphoma MetaADEDB
Bacteraemia MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Barbiturates Positive MetaADEDB
Basal Cell Carcinoma MetaADEDB
Biopsy Bone MetaADEDB
Bladder Catheterisation MetaADEDB
Bladder Discomfort MetaADEDB
Bladder Disorder MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Neck Obstruction MetaADEDB
Bladder Retention MetaADEDB
Bleeding Time Prolonged MetaADEDB
Blood 125-Dihydroxycholecalciferol Decreased MetaADEDB
Blood Aldosterone Increased MetaADEDB
Blood Amylase MetaADEDB
Blood Bilirubin MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Iron Increased MetaADEDB
Blood Test MetaADEDB
Blood Test Abnormal MetaADEDB
Blood Testosterone Decreased MetaADEDB
Blood Testosterone Free Increased MetaADEDB
Blood Testosterone Increased MetaADEDB
Blood Triglycerides Decreased MetaADEDB
Blood Urine Present MetaADEDB
Body Dysmorphic Disorder MetaADEDB
Body Temperature Fluctuation MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Density Decreased MetaADEDB
Bone Disorder MetaADEDB
Bone Graft MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Transplant MetaADEDB
Bone Operation MetaADEDB
Bone Spur MetaADEDB
Bone Swelling MetaADEDB
Bovine Tuberculosis MetaADEDB
Breakthrough Pain MetaADEDB
Breast Cancer Male ADReCS
Breast Cyst MetaADEDB
Breast Discomfort MetaADEDB
Breast Disorder ADReCS
Breast Disorder Male ADReCS
Breast Enlargement ADReCS
Breast Fibrosis MetaADEDB
Breast Hyperplasia MetaADEDB
Breast Induration MetaADEDB
Breast Lump MetaADEDB
Breast Neoplasm MetaADEDB
Breast Pain MetaADEDB
Breast Swelling MetaADEDB
Breast Tenderness ADReCS
Bronchiolitis MetaADEDB
Bulging MetaADEDB
Bulimia MetaADEDB
Bundle Branch Block MetaADEDB
Bundle Branch Block Right MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation Mucosal MetaADEDB
Calcification Pancreatic Duct MetaADEDB
Calculus Ureteric MetaADEDB
Calculus Urinary MetaADEDB
Cancer MetaADEDB
Candida Infection MetaADEDB
Cardiac Ablation MetaADEDB
Cardiac Aneurysm MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Carotid Arteriosclerosis MetaADEDB
Cataract Operation MetaADEDB
Catheter Placement MetaADEDB
Central Nervous System Lesion MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebellar Atrophy MetaADEDB
Cerebral Atrophy MetaADEDB
Cervical Laser Therapy MetaADEDB
Chest Pain MetaADEDB
Chest Wall Mass MetaADEDB
Cholecystectomies MetaADEDB
Cholecystitis Infective MetaADEDB
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Clavicle Fracture MetaADEDB
Clonus MetaADEDB
Coccydynia MetaADEDB
Cold Extremities MetaADEDB
Compression Fracture MetaADEDB
Congenital Knee Deformity MetaADEDB
Constipated MetaADEDB
Cough MetaADEDB
Crackles Lung MetaADEDB
Cryptorchidism MetaADEDB
Csf Protein MetaADEDB
Csf Protein Increased MetaADEDB
Culture Positive MetaADEDB
Cushingoid MetaADEDB
Cutaneous Ulcer MetaADEDB
Dandruff MetaADEDB
Dark Circles Under Eyes MetaADEDB
Debridement MetaADEDB
Decreased Activity MetaADEDB
Decreased Interest MetaADEDB
Decreased Libido MetaADEDB
Deglutition Disorder MetaADEDB
Dementia With Lewy Bodies MetaADEDB
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dental Caries MetaADEDB
Dental Operation MetaADEDB
Dental Pain MetaADEDB
Dental Prosthesis Placement MetaADEDB
Dental Prosthesis User MetaADEDB
Denture Wearer MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermographism MetaADEDB
Device Breakage MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetic Hyperosmolar Coma MetaADEDB
Diarrhea Infectious MetaADEDB
Disturbance In Sexual Arousal ADReCS
Diverticulum MetaADEDB
Dizziness ADReCS
Drug Administration Error MetaADEDB
Drug Dispensing Error MetaADEDB
Drug Ineffective MetaADEDB
Drug Level MetaADEDB
Dry Eye MetaADEDB
Dry Skin MetaADEDB
Dysgeusia MetaADEDB
Dyslipidaemia MetaADEDB
Dyspareunia MetaADEDB
Dysphonia MetaADEDB
Dysuria MetaADEDB
Ear Ache MetaADEDB
Ear Discomfort MetaADEDB
Echocardiogram Abnormal MetaADEDB
Eczema MetaADEDB
Edema Extremities MetaADEDB
Ejaculation Disorder ADReCS
Ejaculation Failure MetaADEDB
Ejection Fraction Abnormal MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Poor R-Wave Progression MetaADEDB
Elevated Prostate Specific Antigen MetaADEDB
Emotional Distress MetaADEDB
Encephalomalacia MetaADEDB
Endodontic Procedure MetaADEDB
Enterococcal Sepsis MetaADEDB
Epididymitis MetaADEDB
Erectile Dysfunction ADReCS
Erosive Gastritis MetaADEDB
Eruption MetaADEDB
Erythema Migrans MetaADEDB
Erythema Nodosum MetaADEDB
Excess Potassium MetaADEDB
Exposure To Chemical Pollution MetaADEDB
Eye Infection MetaADEDB
Eye Pain MetaADEDB
Eyelid Infection MetaADEDB
Eyelid Irritation MetaADEDB
Eyelids Pruritus MetaADEDB
Eyes Sunken MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue MetaADEDB
Febrile Neutropenia MetaADEDB
Feminisation Acquired MetaADEDB
Femoral Arterial Stenosis MetaADEDB
Fistula MetaADEDB
Fistula Discharge MetaADEDB
Fistula Repair MetaADEDB
Flank Pain MetaADEDB
Foot Deformity MetaADEDB
Foreign Body Aspiration MetaADEDB
Formication MetaADEDB
Free Prostate-Specific Antigen Decreased MetaADEDB
Gastric Polyps MetaADEDB
Gastroduodenal Ulcer MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Motility Disorder MetaADEDB
Gastrointestinal Tract Mucosal Discolouration MetaADEDB
General Physical Health Deterioration MetaADEDB
Genital Burning Sensation MetaADEDB
Genital Discomfort MetaADEDB
Genital Disorder Male MetaADEDB
Genital Pain MetaADEDB
Genital Rash MetaADEDB
Gingival Disorder MetaADEDB
Gingival Erythema MetaADEDB
Gingival Oedema MetaADEDB
Gingival Pain MetaADEDB
Gliosis MetaADEDB
Gun Shot Wound MetaADEDB
Gynaecomastia ADReCS
Haematospermia MetaADEDB
Haemorrhoid Operation MetaADEDB
Haemorrhoids MetaADEDB
Hair Colour Changes MetaADEDB
Hair Disease MetaADEDB
Hair Growth Abnormal MetaADEDB
Head Deformity MetaADEDB
Heat Exhaustion MetaADEDB
Hemianopia MetaADEDB
Hepatic Adenoma ADReCS
Hepatic Enzyme MetaADEDB
Hepatic Mass MetaADEDB
Hepatocellular Adenoma SIDER
Hernia Inguinal MetaADEDB
Herpes Zoster MetaADEDB
Hiccough MetaADEDB
Hidradenitis MetaADEDB
High Density Lipoprotein Increased MetaADEDB
Hormone Therapy MetaADEDB
Hot Flash MetaADEDB
Hydronephrosis MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hypercoagulation MetaADEDB
Hypersensitivity ADReCS
Hypertrophy ADReCS
Hypoaesthesia Oral MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypogeusia MetaADEDB
Hyporeflexia MetaADEDB
Hypospadias MetaADEDB
Hypothyroid MetaADEDB
Ileitis MetaADEDB
Iliac Artery Stenosis MetaADEDB
Ill-Defined Disorder MetaADEDB
Immobile MetaADEDB
Immune System Disorder SIDER
Impaired Healing MetaADEDB
Impaired Self-Care MetaADEDB
Impaired Work Ability MetaADEDB
Impotence ADReCS
Incontinence MetaADEDB
Increased Bronchial Secretion MetaADEDB
Increased Upper Airway Secretion MetaADEDB
Infection MetaADEDB
Inflammatory Bowel Disease MetaADEDB
Infusion Site Erythema MetaADEDB
Ingrowing Nail MetaADEDB
Inguinal Hernia Repair MetaADEDB
Inguinal Mass MetaADEDB
Inhalation Therapy MetaADEDB
Initial Insomnia MetaADEDB
Intensive Care MetaADEDB
Intermittent Claudication MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Space Narrowing MetaADEDB
Intestinal Haemorrhage MetaADEDB
Intraocular Lens Implant MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Irritation Skin MetaADEDB
Ischaemia MetaADEDB
Jaw Fracture MetaADEDB
Jaw Operation MetaADEDB
Joint Arthroplasty MetaADEDB
Keratoacanthoma MetaADEDB
Kidney Transplant Rejection MetaADEDB
Kyphosis MetaADEDB
Lentigo MetaADEDB
Libido Decreased ADReCS
Libido Disorder MetaADEDB
Libido Increased MetaADEDB
Ligament Rupture MetaADEDB
Limb Discomfort MetaADEDB
Lipoma Excision MetaADEDB
Lipoprotein (A) Abnormal MetaADEDB
Live Birth MetaADEDB
Local Swelling MetaADEDB
Localised Oedema ADReCS
Loose Tooth MetaADEDB
Loss Of Weight MetaADEDB
Lung Hyperinflation MetaADEDB
Lung Injury MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Lymphoma MetaADEDB
Macula Lutea Degeneration MetaADEDB
Maculopathy MetaADEDB
Malaria MetaADEDB
Male Sexual Dysfunction MetaADEDB
Malignant Nipple Neoplasm Male MetaADEDB
Malignant Tumour Excision MetaADEDB
Marital Problem MetaADEDB
Medical Device Implantation MetaADEDB
Medication Residue MetaADEDB
Melanocytic Naevus MetaADEDB
Meningitides MetaADEDB
Mesenteric Vascular Insufficiency MetaADEDB
Mesenteric Vein Thrombosis MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Metastases To Peritoneum MetaADEDB
Metastases To Reproductive Organ MetaADEDB
Metastases To Skin MetaADEDB
Metastatic Neoplasm MetaADEDB
Micturition Disorder MetaADEDB
Micturition Frequency Decreased MetaADEDB
Micturition Urgency MetaADEDB
Middle Insomnia MetaADEDB
Mouth Pain MetaADEDB
Mucosal Inflammation MetaADEDB
Mucosal Ulceration MetaADEDB
Multi-Organ Disorder MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Enzyme MetaADEDB
Muscle Fatigue MetaADEDB
Muscle Rupture MetaADEDB
Muscle Strain MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Mycoplasma Infection MetaADEDB
Myeloma Recurrence MetaADEDB
Nail Discolouration MetaADEDB
Nail Disorder MetaADEDB
Nail Tinea MetaADEDB
Nasal Odour MetaADEDB
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Nephrolithiasis MetaADEDB
Night Blindness MetaADEDB
Nipple Disorder MetaADEDB
Nipple Pain MetaADEDB
Nipple Swelling MetaADEDB
No Therapeutic Response MetaADEDB
Nocturia MetaADEDB
Nodule Skin MetaADEDB
Obstructive Airways Disorder MetaADEDB
Obstructive Uropathy MetaADEDB
Oedema ADReCS
Oesophageal Dilatation MetaADEDB
Oesophageal Obstruction MetaADEDB
Off Label Use MetaADEDB
Onychalgia MetaADEDB
Open Reduction Of Fracture MetaADEDB
Oral Cavity Fistula MetaADEDB
Oral Discomfort MetaADEDB
Oral Polypectomy MetaADEDB
Orchitis MetaADEDB
Orgasm Abnormal MetaADEDB
Oropharyngeal Discomfort MetaADEDB
Oropharyngeal Pain MetaADEDB
Osteolysis MetaADEDB
Osteomyelitis MetaADEDB
Osteopenia MetaADEDB
Osteoradionecrosis MetaADEDB
Osteosclerosis MetaADEDB
Oxygen Supplementation MetaADEDB
Pain MetaADEDB
Pain Of Skin MetaADEDB
Pain Pelvic MetaADEDB
Painful Respiration MetaADEDB
Palliative Care MetaADEDB
Pancreatitis MetaADEDB
Paraparesis MetaADEDB
Parotid Gland Enlargement MetaADEDB
Penile Haemorrhage MetaADEDB
Penile Pain MetaADEDB
Penile Size Reduced MetaADEDB
Penis Disorder MetaADEDB
Periodontitis MetaADEDB
Peripheral Arterial Occlusive Disease MetaADEDB
Perirectal Abscess MetaADEDB
Peritoneal Neoplasm MetaADEDB
Peroneal Nerve Palsy MetaADEDB
Peyronie Disease MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharmaceutical Product Counterfeit MetaADEDB
Pharyngeal Haemorrhage MetaADEDB
Phimosis MetaADEDB
Physical Disability MetaADEDB
Pitting Oedema MetaADEDB
Plasmacytoma MetaADEDB
Platelet Disorder MetaADEDB
Pleural Fibrosis MetaADEDB
Pollakiuria MetaADEDB
Polyhydramnios MetaADEDB
Polyneuropathy MetaADEDB
Polyp MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Procedural Infection MetaADEDB
Post Procedural Pain MetaADEDB
Posterior Capsule Opacification MetaADEDB
Posterior Capsulotomy MetaADEDB
Primary Sequestrum MetaADEDB
Proctalgia MetaADEDB
Product Quality Issue MetaADEDB
Prostate Cancer ADReCS
Prostate Cancer Metastatic MetaADEDB
Prostate Cancer Stage I MetaADEDB
Prostate Examination Abnormal MetaADEDB
Prostate Tenderness MetaADEDB
Prostatectomy MetaADEDB
Prostatic Obstruction MetaADEDB
Prostatic Specific Antigen MetaADEDB
Prostatic Specific Antigen Decreased MetaADEDB
Prostatitis MetaADEDB
Prostatomegaly MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Level Decreased MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pseudofolliculitis Barbae MetaADEDB
Pseudomonal Bacteraemia MetaADEDB
Psychosexual Disorder MetaADEDB
Pulpitis Dental MetaADEDB
Purulence MetaADEDB
Purulent Discharge MetaADEDB
Quality Of Life Decreased MetaADEDB
Radical Mastectomy MetaADEDB
Rash ADReCS
Rectal Fistula Repair MetaADEDB
Rectal Spasm MetaADEDB
Red Cell Distribution Width Increased MetaADEDB
Renal Cyst MetaADEDB
Renal Mass MetaADEDB
Respiratory Tract Infection Fungal MetaADEDB
Resuscitation MetaADEDB
Retinal Ischaemia MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retrograde Ejaculation MetaADEDB
Retroperitoneal Lymphadenopathy MetaADEDB
Rhinorrhea MetaADEDB
Rhonchi MetaADEDB
Rib Fracture MetaADEDB
Sclc MetaADEDB
Scrotal Swelling MetaADEDB
Seborrhoeic Keratosis MetaADEDB
Secretion Discharge MetaADEDB
Semen Discolouration MetaADEDB
Semen Viscosity Abnormal MetaADEDB
Semen Volume Decreased MetaADEDB
Sick Sinus Syndrome MetaADEDB
Sinus Bradycardia MetaADEDB
Sinus Disorder MetaADEDB
Skin Lesion MetaADEDB
Skin Necrosis MetaADEDB
Skin Neoplasm Excision MetaADEDB
Skin Reaction ADReCS
Skin Wrinkling MetaADEDB
Sleep Disorder MetaADEDB
Small Intestinal Obstruction MetaADEDB
Small Intestine Carcinoma MetaADEDB
Social Avoidant Behaviour ADReCS
Social Problem MetaADEDB
Soft Tissue Inflammation MetaADEDB
Sperm Count Decreased MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Fusion Surgery MetaADEDB
Spinal Haemangioma MetaADEDB
Spinal Laminectomy MetaADEDB
Spondylolysis MetaADEDB
Spondylopathy Traumatic MetaADEDB
Squamous Cell Carcinoma Of Skin MetaADEDB
Stasis Dermatitis MetaADEDB
Stem Cell Transplant MetaADEDB
Stent Placement MetaADEDB
Suture Insertion MetaADEDB
Sweat Gland Infection MetaADEDB
Swollen Tongue MetaADEDB
Talipes MetaADEDB
Tenderness ADReCS
Tendon Graft MetaADEDB
Tendon Pain MetaADEDB
Testes Pain MetaADEDB
Testicular Atrophy MetaADEDB
Testicular Mass MetaADEDB
Testis Discomfort MetaADEDB
Therapeutic Procedure MetaADEDB
Therapeutic Response Decreased MetaADEDB
Therapeutic Response Unexpected MetaADEDB
Tinea Cruris MetaADEDB
Tinnitus MetaADEDB
Tongue Black Hairy MetaADEDB
Tongue Haemorrhage MetaADEDB
Tooth Deposit MetaADEDB
Tooth Disease MetaADEDB
Tooth Extraction MetaADEDB
Tooth Impacted MetaADEDB
Tooth Infection MetaADEDB
Tooth Loss MetaADEDB
Tracheo-Oesophageal Fistula MetaADEDB
Transaminases Increased MetaADEDB
Transurethral Prostatectomy MetaADEDB
Tumour Necrosis MetaADEDB
Urethral Discharge MetaADEDB
Urethral Stenosis MetaADEDB
Urinary Bladder Polyp MetaADEDB
Urinary Retention Postoperative MetaADEDB
Urinary Tract Disorder MetaADEDB
Urinary Tract Pain MetaADEDB
Urine Analysis Abnormal MetaADEDB
Urine Flow Decreased MetaADEDB
Urine Odour Abnormal MetaADEDB
Urine Output Increased MetaADEDB
Urosepsis MetaADEDB
Urticaria ADReCS
Vaccination Complication MetaADEDB
Vasectomy MetaADEDB
Vasospasm MetaADEDB
Venoocclusive Disease MetaADEDB
Venous Insufficiency MetaADEDB
Vertebroplasty MetaADEDB
Vessel Puncture Site Haematoma MetaADEDB
Volvulus MetaADEDB
Walking Aid User MetaADEDB
Wheeze MetaADEDB
Withdrawn SIDER
Wound MetaADEDB
Wound Closure MetaADEDB
Wound Debridement MetaADEDB
Wound Drainage MetaADEDB
Xanthogranuloma MetaADEDB

InAADR: Drug-Protein-ADRs database