InAADR

Drug Information

Drug Name: Doxazosin (74191-85-8)
PubChem ID: 3157
SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
InchiKey: RUZYUOTYCVRMRZ-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic alpha-1 Receptor Antagonists, Adrenergic alpha-Antagonists, Adrenergic Antagonists, Antihypertensive Agents, Cardiovascular Agents, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 451.483
LogP: 1.7178
Ring Count: 3
Hydrogen Bond Acceptor Count: 9
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 112.27

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Abscess MetaADEDB
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Strangulated Hernia MetaADEDB
Abnormal Movements MetaADEDB
Abscess MetaADEDB
Abscess Jaw MetaADEDB
Accelerated Hypertension MetaADEDB
Acidosis MetaADEDB
Actinic Keratosis MetaADEDB
Actinomycosis MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Adenocarcinoma MetaADEDB
Adenoma MetaADEDB
Adh Inappropriate MetaADEDB
Adrenal Neoplasm MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability ADReCS
Afib MetaADEDB
Agitation ADReCS
Albuminuria MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Reaction ADReCS
Allergic Rhinitis MetaADEDB
Alopecia ADReCS
Altered State Of Consciousness MetaADEDB
Alveolitis MetaADEDB
Amnesia ADReCS
Amyloidosis MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Anal Discomfort MetaADEDB
Anastomotic Complication MetaADEDB
Aneurysm ADReCS
Angiitis MetaADEDB
Angina MetaADEDB
Angina Pectoris ADReCS
Angina Unstable MetaADEDB
Angioedema MetaADEDB
Anhedonia MetaADEDB
Anorectal Discomfort ADReCS
Anorexia ADReCS
Anxiety ADReCS
Aortic Regurgitation MetaADEDB
Aortic Valve Sclerosis MetaADEDB
Apathy ADReCS
Aplasia Pure Red Cell MetaADEDB
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stenosis MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriospasm Coronary MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Aseptic Necrosis Bone MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asystole MetaADEDB
Ataxia ADReCS
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrial Flutter MetaADEDB
Atrial Thrombosis MetaADEDB
Atrioventricular Block MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Back Pain ADReCS
Belligerence MetaADEDB
Benign Biliary Neoplasm MetaADEDB
Bile Duct Stone MetaADEDB
Birth Defect MetaADEDB
Bladder Cancer MetaADEDB
Bladder Pain ADReCS
Bleb MetaADEDB
Blindness ADReCS
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatinine MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid Increased ADReCS
Body Temperature Increased ADReCS
Bone Fracture Spontaneous MetaADEDB
Bone Marrow Failure MetaADEDB
Bradyarrhythmia MetaADEDB
Bradycardia ADReCS
Breast Neoplasm ADReCS
Breast Pain ADReCS
Bronchiolitis MetaADEDB
Bronchitis ADReCS
Bronchospasm ADReCS
Bronchospasm Aggravated ADReCS
Calculus Of Kidney SIDER
Candida Infection MetaADEDB
Carcinoma SIDER
Carcinoma Of Lung SIDER
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure ADReCS
Cardiac Fibrillation ADReCS
Cardiac Ischemia MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Operation MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomegaly MetaADEDB
Cardiotoxicity MetaADEDB
Carotid Bruit MetaADEDB
Cataract ADReCS
Cataract Diabetic MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cerebration Impaired SIDER
Cerebrovascular Accident ADReCS
Cerebrovascular Disorder ADReCS
Cervicalgia MetaADEDB
Chest Pain ADReCS
Chills ADReCS
Cholelithiasis ADReCS
Cholestasis ADReCS
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Claudication SIDER
Clavicle Fracture MetaADEDB
Coccydynia MetaADEDB
Coeliac Artery Compression Syndrome MetaADEDB
Colitis Ischaemic MetaADEDB
Colon Adenoma MetaADEDB
Colonic Polyp MetaADEDB
Coma MetaADEDB
Common Cold SIDER
Concomitant Disease Aggravated MetaADEDB
Confusional State ADReCS
Congenital Eye Disorder SIDER
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Contracture MetaADEDB
Convulsion ADReCS
Coronary Artery Insufficiency MetaADEDB
Coronary Artery Occlusion MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coronary Disease MetaADEDB
Costochondritis MetaADEDB
Cough ADReCS
Coughing Blood MetaADEDB
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Creatinine Renal Clearance Decreased MetaADEDB
Crocodile Tears Syndrome ADReCS
Cystitis ADReCS
Cystitis Noninfective ADReCS
Deafness ADReCS
Death ADReCS
Decreased Appetite ADReCS
Deglutition Disorder MetaADEDB
Dehydration ADReCS
Dental Abscess MetaADEDB
Depersonalisation ADReCS
Depressed Level Of Consciousness MetaADEDB
Depression ADReCS
Dermal Cyst MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Dermatosis MetaADEDB
Diabetes MetaADEDB
Diabetes Complications MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Dilatation Atrial MetaADEDB
Diplopia ADReCS
Discomfort ADReCS
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Diverticular Perforation MetaADEDB
Diverticulitis ADReCS
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Dizziness Postural ADReCS
Drug Diversion MetaADEDB
Drug Level Changed MetaADEDB
Dry Mouth ADReCS
Dry Skin ADReCS
Dry Throat MetaADEDB
Duodenal Ulcer MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Duodenal Ulcer Perforation MetaADEDB
Dysgeusia ADReCS
Dyskinesia ADReCS
Dyslipidemias MetaADEDB
Dyspepsia ADReCS
Dysphasia MetaADEDB
Dysphonia MetaADEDB
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysuria ADReCS
Ear Ache MetaADEDB
Ear Discharge MetaADEDB
Ear Infection ADReCS
Ear Pain ADReCS
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Eczema ADReCS
Edema Extremities MetaADEDB
Ejaculation Failure ADReCS
Electrocardiogram Abnormal SIDER
Electrocardiogram Qrs Complex MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalopathy ADReCS
Encephalopathy Hypertensive MetaADEDB
Enlargement Abdomen SIDER
Enterobacter Infection MetaADEDB
Epididymitis ADReCS
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erosive Gastritis MetaADEDB
Erythema Of Eyelid MetaADEDB
Exacerbation Of Psoriasis ADReCS
Excess Potassium MetaADEDB
Expired Drug Administered MetaADEDB
Extrasystoles MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Disorder SIDER
Eye Pain ADReCS
Eye Pruritus MetaADEDB
Eye Rolling MetaADEDB
Eyelid Retraction MetaADEDB
Face Oedema ADReCS
Faecal Incontinence ADReCS
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Feeding Tube Complication MetaADEDB
Feeling Abnormal ADReCS
Fib MetaADEDB
Flat Affect ADReCS
Flatulence ADReCS
Floppy SIDER
Floppy Iris Syndrome ADReCS
Flushing ADReCS
Free Thyroxine Index Increased MetaADEDB
Fungal Infection ADReCS
Gastric Hyperplasia MetaADEDB
Gastric Ulcer ADReCS
Gastroduodenal Ulcer MetaADEDB
Gastroenteritis ADReCS
Gastrointestinal Arteriovenous Malformation MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Mucosal Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Tract Irritation ADReCS
Gastrointestinal Tract Mucosal Discolouration MetaADEDB
Gaze Palsy MetaADEDB
Genital Erosion MetaADEDB
Gingival Infection MetaADEDB
Gingivitis ADReCS
Gout ADReCS
Granulocytosis MetaADEDB
Grimacing MetaADEDB
Gynaecomastia ADReCS
Haematocrit Decreased ADReCS
Haematoma MetaADEDB
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Hair Colour Changes MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Failure MetaADEDB
Heart Valve Incompetence MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis Cholestatic ADReCS
Hepatosplenic T-Cell Lymphoma MetaADEDB
Hepatosplenomegaly MetaADEDB
Hernia ADReCS
Herpes Nos SIDER
Herpes Simplex ADReCS
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hiccough MetaADEDB
Hot Flush ADReCS
Hyperacusia MetaADEDB
Hypercholesterolemia MetaADEDB
Hypercoagulation MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkinesia ADReCS
Hyperlipaemia MetaADEDB
Hyperparathyroidism Secondary MetaADEDB
Hyperpigmentation MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertension Worsened SIDER
Hypertensive Cardiomyopathy MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hypertonia ADReCS
Hypertrophy ADReCS
Hypertrophy Left Ventricular MetaADEDB
Hyperuricaemia ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Facial MetaADEDB
Hypokalaemia ADReCS
Hypokinesia ADReCS
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypothyroid MetaADEDB
Hypotonia ADReCS
Ild MetaADEDB
Ill-Defined Disorder ADReCS
Immunosuppressant Drug Level MetaADEDB
Impetigo MetaADEDB
Impingement Syndrome MetaADEDB
Impotence ADReCS
Incontinence ADReCS
Increased Appetite ADReCS
Infarction ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Influenza ADReCS
Influenza Like Illness ADReCS
Influenza-Like Symptoms SIDER
Infusion Site Mobility Decreased MetaADEDB
Injection Site Cellulitis MetaADEDB
Injury Asphyxiation MetaADEDB
Inner Ear Inflammation MetaADEDB
Insomnia ADReCS
Insulin Resistance MetaADEDB
Intermittent Claudication ADReCS
Internal Fixation Of Fracture MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intraoperative Floppy Iris Syndrome ADReCS
Iron Deficiency Anaemia MetaADEDB
Ischaemia ADReCS
Ischaemic Cerebral Infarction MetaADEDB
Jaundice ADReCS
Jaw Disorder MetaADEDB
Joint Contracture MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Joint Sprain MetaADEDB
Knee Operation MetaADEDB
Lacrimal Disorder ADReCS
Lacrimation SIDER
Lacrimation Increased ADReCS
Lacunar Infarction MetaADEDB
Leg Cramps ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Lip Dry MetaADEDB
Livedo Reticularis MetaADEDB
Liver Function Test Abnormal ADReCS
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lung Fibrosis MetaADEDB
Lung Neoplasm Malignant ADReCS
Lyell MetaADEDB
Lymphadenopathy ADReCS
Lymphocyte Stimulation Test Positive MetaADEDB
Malaise ADReCS
Malnourished MetaADEDB
Mandibulectomy MetaADEDB
Melaena ADReCS
Menopausal Symptoms ADReCS
Mental Disability ADReCS
Mental Disorder SIDER
Metatarsalgia MetaADEDB
Micturition Disorder ADReCS
Micturition Urgency MetaADEDB
Migraine ADReCS
Mitral Valve Sclerosis MetaADEDB
Mononeuritis MetaADEDB
Mood Swings ADReCS
Movement Disorder ADReCS
Mucosal Erosion MetaADEDB
Mucous Membrane Disorder MetaADEDB
Muscle Relaxant Therapy ADReCS
Muscle Spasms ADReCS
Muscle Twitching ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness MetaADEDB
Myalgia ADReCS
Mycobacterium Avium Complex Infection MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Myoglobin Urine Present MetaADEDB
Myopia ADReCS
Nail Disorder ADReCS
Nasal Congestion MetaADEDB
Nasal Discomfort MetaADEDB
Nasal Polyp MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Neovascularisation MetaADEDB
Nephrectomy MetaADEDB
Nephrogenic Anaemia MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nephrolithiasis ADReCS
Nervousness ADReCS
Neumonia MetaADEDB
Neutropenia ADReCS
Neutrophilia MetaADEDB
Nightmare ADReCS
Nocturia ADReCS
Non-Hodgkin Lymphoma MetaADEDB
Oedema ADReCS
Oedema Mucosal MetaADEDB
Oesophagitis ADReCS
Oliguria ADReCS
Optic Ischaemic Neuropathy MetaADEDB
Oral Disorder MetaADEDB
Oroantral Fistula MetaADEDB
Orthostatic Hypotension ADReCS
Osteomyelitis MetaADEDB
Osteoradionecrosis MetaADEDB
Osteosclerosis MetaADEDB
Otitis SIDER
Otitis Media ADReCS
Overdose MetaADEDB
Pain ADReCS
Pain Of Skin ADReCS
Pallor ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitations ADReCS
Paraesthesia ADReCS
Paresis ADReCS
Parosmia ADReCS
Pedal Pulse Absent MetaADEDB
Performance Status Decreased MetaADEDB
Perineal Pain ADReCS
Perinephric Collection MetaADEDB
Peripheral Ischaemia ADReCS
Peritoneal Dialysis MetaADEDB
Peritonitis MetaADEDB
Peritonitis Bacterial MetaADEDB
Pharyngitis ADReCS
Photophobia ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pneumonia ADReCS
Pneumonia Fungal MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Pollakiuria ADReCS
Polymyalgia SIDER
Polymyalgia Rheumatica ADReCS
Polymyositis MetaADEDB
Polyuria ADReCS
Post Nasal Drip MetaADEDB
Prescribed Overdose MetaADEDB
Priapism ADReCS
Procedural Hypotension MetaADEDB
Proctalgia ADReCS
Productive Cough MetaADEDB
Prostatic Disorder ADReCS
Prostatic Hyperplasia MetaADEDB
Prostatism MetaADEDB
Prostatomegaly MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pruritus Genital ADReCS
Psoriasis ADReCS
Psoriasis Flare-Up SIDER
Pulmonary Air Leakage MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Hypertension MetaADEDB
Purpura ADReCS
Pyrexia ADReCS
Radicular Syndrome MetaADEDB
Rash ADReCS
Rash Erythematous ADReCS
Rash Maculo-Papular ADReCS
Rebound Hypertension MetaADEDB
Rectal Haemorrhage ADReCS
Rectal Tenesmus ADReCS
Red Blood Cell Count Increased MetaADEDB
Reflux Esophagitis MetaADEDB
Renal Impairment MetaADEDB
Renal Pain ADReCS
Renal Tubular Acidosis MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Disorder ADReCS
Respiratory Failure MetaADEDB
Respiratory Tract Infection ADReCS
Reticulocyte Count Decreased MetaADEDB
Retinal Tear MetaADEDB
Retinopathy Hypertensive MetaADEDB
Retrograde Ejaculation ADReCS
Rhinitis ADReCS
Rhinorrhea MetaADEDB
Rhythm Idioventricular MetaADEDB
Rigors SIDER
Scotoma ADReCS
Seborrhoeic Dermatitis ADReCS
Self Injurious Behaviour MetaADEDB
Semen Abnormal SIDER
Semen Analysis Abnormal ADReCS
Sepsis ADReCS
Sexual Dysfunction ADReCS
Sexual Dysfunction Physiological MetaADEDB
Shock ADReCS
Sick Sinus Syndrome MetaADEDB
Sigmoidoscopy Abnormal MetaADEDB
Sinusitis ADReCS
Skin Desquamation MetaADEDB
Skin Disorder ADReCS
Skin Fibrosis MetaADEDB
Skin Hypertrophy ADReCS
Skin Lesion MetaADEDB
Skin Necrosis MetaADEDB
Skin Tightness MetaADEDB
Sleep Apnea MetaADEDB
Sleep Disorder MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Somnolence ADReCS
Speech Disorder ADReCS
Spinal Osteoarthritis MetaADEDB
Splenectomy MetaADEDB
Starvation MetaADEDB
Stress MetaADEDB
Stroke MetaADEDB
Subarachnoid Haemorrhage ADReCS
Sudden Death ADReCS
Sweating SIDER
Sweating Increased SIDER
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tendon Disorder ADReCS
Tension ADReCS
Thinking Abnormal ADReCS
Thirst ADReCS
Thrombocytopenia ADReCS
Tinnitus ADReCS
Tongue Disorder ADReCS
Tooth Disorder ADReCS
Tooth Erosion MetaADEDB
Tooth Hypoplasia ADReCS
Tremor ADReCS
Tumour Lysis Syndrome MetaADEDB
Ulcer ADReCS
Upper Limb Fracture MetaADEDB
Upper Respiratory Tract Infection ADReCS
Upper Respiratory Tract Inflammation MetaADEDB
Urinary Bladder Neck Obstruction MetaADEDB
Urinary Bladder Overactive MetaADEDB
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Infection ADReCS
Urination Disorders MetaADEDB
Urine Abnormality ADReCS
Urine Analysis Abnormal ADReCS
Urine Output Increased ADReCS
Urologic Diseases MetaADEDB
Urticaria ADReCS
Vascular Purpura ADReCS
Vascular Resistance Systemic Decreased MetaADEDB
Venous Thrombosis Limb MetaADEDB
Vertebrobasilar Insufficiency MetaADEDB
Vertigo ADReCS
Viral Infection ADReCS
Vision Abnormal ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Decreased ADReCS
Weight Increased ADReCS
Xerosis MetaADEDB

InAADR: Drug-Protein-ADRs database