InAADR

Drug Information

Drug Name: Dipyridamole (58-32-2)
PubChem ID: 3108
SMILES: C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
InchiKey: IZEKFCXSFNUWAM-UHFFFAOYSA-N
Therapeutic Category: Cardiovascular Agents, Enzyme Inhibitors, Hematologic Agents, Phosphodiesterase Inhibitors, Platelet Aggregation Inhibitors, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 504.636
LogP: -0.0176
Ring Count: 2
Hydrogen Bond Acceptor Count: 12
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 145.44

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Atenolol (29122-68-7) Asystole Additive Not established Asystole and bradycardia during dipyridamole stress testing in patients receiving beta blockers
Atenolol (29122-68-7) Bradycardia Additive Not established Asystole and bradycardia during dipyridamole stress testing in patients receiving beta blockers
Famotidine (76824-35-6) Reduce The Bioavailability Of Dipyridamole Antagonistic FAmotidine raises the stomach pH significantly would be likely to reduce the dissolution and absorption of dipyridamole pH-related changes in the absorption of dipyridamole in the elderly
Theophylline (58-55-9) Reduce The Effects Of Dipyridamole Antagonistic theophylline might antagonise effects of dipyridamole becauseact as competitive antagonists of adenosine Effect of maintenance oral theophylline on dipyridamole-thallium-201 myocardial imaging using SPECT and dipyridamole-induced hemodynamic changes
Adenosine (58-61-7) Bradycardia Antagonistic Not fully understood. Part of the explanation is that dipyridamole increases plasma levels of endogenous adenosine by inhibiting its uptake into cells Intravenous adenosine in the treatment of supraventricular tachycardia: a dose-ranging study and interaction with dipyridamole

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Garlic Inhibit The Action Of Platelets http://ummedu/health/medical/altmed/herb-interaction/possible-interactions-with-garlic

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
2',5'-Oligoadenylate Synthetase Test Increased MetaADEDB
Abdominal Abscess MetaADEDB
Abdominal Discomfort ADReCS
Abdominal Distress ADReCS
Abdominal Pain ADReCS
Abdominal Symptom MetaADEDB
Abnormal Ecg MetaADEDB
Abnormal Faeces MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abscess Drainage MetaADEDB
Accommodation Disorder MetaADEDB
Acidosis MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myeloid Leukaemia Recurrent MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adrenal Neoplasm MetaADEDB
Adynamic Ileus MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcohol Consumption MetaADEDB
Alcoholic Intoxication MetaADEDB
Alopecia ADReCS
Altered State Of Consciousness MetaADEDB
Alzheimer Disease MetaADEDB
Anaemia MetaADEDB
Anal Fistula MetaADEDB
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anaphylaxis MetaADEDB
Angina MetaADEDB
Angina Pectoris ADReCS
Angiodysplasia MetaADEDB
Angioedema ADReCS
Anorectal Discomfort ADReCS
Anorexia MetaADEDB
Anti-Hbc Antibody MetaADEDB
Anti-Hbc Igg Antibody Positive MetaADEDB
Anti-Hbs Antibody Positive MetaADEDB
Anuria MetaADEDB
Anxiety ADReCS
Aortic Arteriosclerosis MetaADEDB
Apathy MetaADEDB
Aphonia MetaADEDB
Apnea MetaADEDB
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arteriovenous Shunt Operation MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Atrial Fibrillation ADReCS
Atrioventricular Block ADReCS
Atrioventricular Block First Degree MetaADEDB
Atrophy MetaADEDB
Back Injury MetaADEDB
Back Pain ADReCS
Bacterial Infection MetaADEDB
Bacterial Pneumonia MetaADEDB
Beta 2 Microglobulin Urine Increased MetaADEDB
Biopsy MetaADEDB
Birth Defect MetaADEDB
Bladder Neck Operation MetaADEDB
Bladder Retention MetaADEDB
Bleb MetaADEDB
Block Heart SIDER
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Immunoglobulin A Decreased MetaADEDB
Blood Immunoglobulin G Decreased MetaADEDB
Blood Immunoglobulin M Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Iron Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Uric Acid Decreased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Density Decreased MetaADEDB
Bone Marrow Failure MetaADEDB
Bradycardia ADReCS
Brain Diseases MetaADEDB
Brain Ischemia MetaADEDB
Brain Oedema MetaADEDB
Breast Pain ADReCS
Bronchial Spasm MetaADEDB
Bronchospasm ADReCS
Bulging MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation Mucosal MetaADEDB
Bursitis MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Calcinosis MetaADEDB
Calcium Deficiency MetaADEDB
Cardiac Arrest ADReCS
Cardiac Death ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Ischemia MetaADEDB
Cardiac Murmur MetaADEDB
Cardiomyopathy ADReCS
Cardiomyopathy Dilated MetaADEDB
Carotid Artery Occlusion MetaADEDB
Cell Marker Increased MetaADEDB
Cerebellar Infarction MetaADEDB
Cerebral Artery Occlusion MetaADEDB
Cerebral Ischaemia ADReCS
Cerebrovascular Accident ADReCS
Cervicalgia MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Chills ADReCS
Cholelithiasis ADReCS
Cholestasis MetaADEDB
Claudication SIDER
Clavicle Fracture MetaADEDB
Clostridial Infection MetaADEDB
Clotting MetaADEDB
Computerised Tomogram MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctival Erosion MetaADEDB
Coordination Abnormal ADReCS
Coronary Artery Disease MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coronary Disease MetaADEDB
Coronary Vasospasm MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Cushingoid MetaADEDB
Cutaneous Ulcer MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Death ADReCS
Debridement MetaADEDB
Decreased Interest MetaADEDB
Dental Caries MetaADEDB
Depersonalisation ADReCS
Depressed Level Of Consciousness MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Device Failure MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Dilatation Pathologic MetaADEDB
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disease Recurrence MetaADEDB
Disinhibition MetaADEDB
Disorder Renal MetaADEDB
Diverticulitis MetaADEDB
Diverticulitis Intestinal Haemorrhagic MetaADEDB
Dizziness ADReCS
Drug Interaction MetaADEDB
Dry Mouth ADReCS
Duodenal Ulcer Haemorrhage MetaADEDB
Dysgeusia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyslalia MetaADEDB
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphonia ADReCS
Dyspnea MetaADEDB
Dyspnoea ADReCS
Ear Pain ADReCS
Ear Tube Insertion MetaADEDB
Eating Disorder MetaADEDB
Eczema MetaADEDB
Electrocardiogram Abnormal SIDER
Electrocardiogram Change SIDER
Electrocardiogram T Wave Inversion MetaADEDB
Emotional Distress MetaADEDB
Empyema MetaADEDB
Enema Administration MetaADEDB
Eosinophil Percentage Increased MetaADEDB
Epidermolysis MetaADEDB
Epistaxis MetaADEDB
Epstein-Barr Virus Associated Lymphoproliferative Disorder MetaADEDB
Erectile Dysfunction MetaADEDB
Eructation ADReCS
Erythema MetaADEDB
Erythema Migrans MetaADEDB
Erythema Multiforme MetaADEDB
Eustachian Tube Disorder MetaADEDB
Excess Potassium MetaADEDB
Extrapyramidal Disorder MetaADEDB
Extrasystoles ADReCS
Eye Oedema MetaADEDB
Eye Pain ADReCS
Eye Swelling MetaADEDB
Eyelid Pain MetaADEDB
Faecaloma MetaADEDB
Fatigue ADReCS
Fear Of Disease MetaADEDB
Feeling Abnormal ADReCS
Fibroadenoma Of Breast MetaADEDB
Flatulence ADReCS
Flushing ADReCS
Focal Glomerulosclerosis MetaADEDB
Food Intolerance MetaADEDB
Foot Fracture MetaADEDB
Fracture Nonunion MetaADEDB
Gallstones MetaADEDB
Gambling MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Diseases MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Ulcer MetaADEDB
General Physical Condition MetaADEDB
General Physical Health Deterioration MetaADEDB
Genital Rash MetaADEDB
Gingival Erythema MetaADEDB
Gingival Pain MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephritis Membranoproliferative MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Gout MetaADEDB
Haemarthrosis MetaADEDB
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heart Block MetaADEDB
Heart Diseases MetaADEDB
Heart Failure MetaADEDB
Heat Exhaustion MetaADEDB
Heat Illness MetaADEDB
Hemolytic-Uremic Syndrome MetaADEDB
Hemorrhage MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatic Haematoma MetaADEDB
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Herpes Virus Infection MetaADEDB
Hot Flush ADReCS
Hyperemia MetaADEDB
Hyperhidrosis ADReCS
Hypersensitivity ADReCS
Hypersexuality MetaADEDB
Hypertension ADReCS
Hypertension Pulmonary MetaADEDB
Hypertonia ADReCS
Hypertonic Bladder MetaADEDB
Hyperventilation ADReCS
Hypoaesthesia ADReCS
Hypogammaglobulinaemia MetaADEDB
Hypotension ADReCS
Ild MetaADEDB
Ill-Defined Disorder ADReCS
Impaired Healing MetaADEDB
Implant Site Infection MetaADEDB
Impulse Control Disorders MetaADEDB
Incontinence MetaADEDB
Increased Appetite ADReCS
Increased Bronchial Secretion MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection MetaADEDB
Injection Site Erosion MetaADEDB
Injection Site Infection MetaADEDB
Injection Site Pain ADReCS
Injection Site Reaction ADReCS
Interleukin-2 Receptor Increased MetaADEDB
Intermittent Claudication ADReCS
International Normalised Ratio Increased MetaADEDB
Interstitial Nephritis MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intraoperative Complications MetaADEDB
Ischaemia ADReCS
Ischemia MetaADEDB
Ischemic Attack Transient MetaADEDB
Jaw Disorder MetaADEDB
Joint Arthroplasty MetaADEDB
Joint Effusion MetaADEDB
Joint Sprain MetaADEDB
Kidney Failure MetaADEDB
Kidney Pain MetaADEDB
Klebsiella Sepsis MetaADEDB
Lacrimation Increased MetaADEDB
Laryngeal Disorder MetaADEDB
Laryngeal Oedema ADReCS
Laryngospasm ADReCS
Lethargy MetaADEDB
Leukocytosis MetaADEDB
Leukopenia Neonatal MetaADEDB
Life Expectancy Shortened MetaADEDB
Lip Haemorrhage MetaADEDB
Lip Ulceration MetaADEDB
Loss Of Consciousness ADReCS
Lung Infection Pseudomonal MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Mean Cell Volume Decreased MetaADEDB
Meniere Disease MetaADEDB
Meningioma MetaADEDB
Meniscus Lesion MetaADEDB
Menopausal Symptoms ADReCS
Metastases To Meninges MetaADEDB
Metastases To Spine MetaADEDB
Middle Ear Effusion MetaADEDB
Migraine ADReCS
Migraine Disorders MetaADEDB
Mitral Valve Insufficiency MetaADEDB
Mitral Valve Sclerosis MetaADEDB
Monarthritis MetaADEDB
Mouth Pain MetaADEDB
Mumps MetaADEDB
Muscle Spasms ADReCS
Muscle Strain MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myocardial Infarction ADReCS
Myocardial Ischemia MetaADEDB
Myocardial Stunning MetaADEDB
Myringotomy MetaADEDB
Nausea ADReCS
Neoplasms MetaADEDB
Nephropathy Toxic MetaADEDB
Nephrosis MetaADEDB
Nervousness ADReCS
Nocardiosis MetaADEDB
Nuclear Magnetic Resonance Imaging MetaADEDB
Oedema ADReCS
Oedema Mouth MetaADEDB
Oliguria MetaADEDB
Open Wound MetaADEDB
Operative Haemorrhage ADReCS
Orthostatic Hypotension ADReCS
Osteolysis MetaADEDB
Pain ADReCS
Palpitations ADReCS
Paraesthesia ADReCS
Paraplegia MetaADEDB
Paresthesia MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Neoplasm MetaADEDB
Perineal Pain ADReCS
Periodontal Disease MetaADEDB
Periodontitis MetaADEDB
Peritoneal Dialysis MetaADEDB
Peritoneal Fibrosis MetaADEDB
Pharyngitis ADReCS
Pharyngolaryngeal Discomfort MetaADEDB
Photophobia MetaADEDB
Platelet Count MetaADEDB
Platelet Disorder MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion MetaADEDB
Pleuritic Pain ADReCS
Poriomania MetaADEDB
Postoperative Wound Complication MetaADEDB
Proctalgia ADReCS
Protein Total Decreased MetaADEDB
Proteinuria MetaADEDB
Pruritus ADReCS
Pruritus Generalised MetaADEDB
Pseudomonal Sepsis MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Mass MetaADEDB
Pulmonary Oedema ADReCS
Pulmonary Radiation Injury MetaADEDB
Rash ADReCS
Rash Generalised MetaADEDB
Rectal Tenesmus ADReCS
Renal Artery Stenosis MetaADEDB
Renal Pain ADReCS
Renal Tubular Disorder MetaADEDB
Renal Tubular Necrosis MetaADEDB
Reperfusion Injury MetaADEDB
Respiratory Disorder MetaADEDB
Retinal Bleeding MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinitis ADReCS
Rigors SIDER
Scratch MetaADEDB
Self-Medication MetaADEDB
Sequestrectomy MetaADEDB
Serum Ferritin Increased MetaADEDB
Shock ADReCS
Shock Cardiogenic MetaADEDB
Sinus Arrest Cardiac MetaADEDB
Sinus Bradycardia MetaADEDB
Skin Lesion MetaADEDB
Somnolence ADReCS
Spinal Disorder MetaADEDB
Streptococcal Infection MetaADEDB
Stress Incontinence MetaADEDB
Stridor MetaADEDB
Stroke MetaADEDB
Subarachnoid Hemorrhage MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Supraventricular Tachycardia ADReCS
Sweating Increased SIDER
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Takotsubo Cardiomyopathy MetaADEDB
Tension ADReCS
Thirst ADReCS
Throat Cancer MetaADEDB
Thrombocytopenia ADReCS
Thrombosis MetaADEDB
Tinnitus ADReCS
Toe Amputation MetaADEDB
Tongue Disorder MetaADEDB
Tooth Loss MetaADEDB
Torsade De Pointes MetaADEDB
Transient Cerebral Ischemia SIDER
Transient Ischaemic Attack ADReCS
Tremor ADReCS
Troponin Increased MetaADEDB
Urethral Dilatation MetaADEDB
Urethral Fistula MetaADEDB
Urinary Tract Operation MetaADEDB
Urticaria ADReCS
Varicose Vein Operation MetaADEDB
Ventricular Arrhythmia ADReCS
Ventricular Dysfunction Left MetaADEDB
Ventricular Fibrillation ADReCS
Ventricular Premature Complexes MetaADEDB
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database