InAADR

Drug Information

Drug Name: Diazoxide (364-98-7)
PubChem ID: 3019
SMILES: CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
InchiKey: GDLBFKVLRPITMI-UHFFFAOYSA-N
Therapeutic Category: Antihypertensive Agents, Cardiovascular Agents, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 230.676
LogP: 1.8726
Ring Count: 1
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 58.53

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Phenytoin (57-41-0) Seizure Control Lost Antagonistic diazoxide increases the metabolism and the clearance of phenytoin from the body. The half-life of diazoxide is possibly reduced by phenytoin Drug interaction: diazoxide and diphenylhydantoin

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Acute Coronary Syndrome ADReCS
Acute Kidney Injury MetaADEDB
Ageusia ADReCS
Albuminuria ADReCS
Anemia MetaADEDB
Angina Pectoris ADReCS
Anorexia ADReCS
Anxiety ADReCS
Apnea MetaADEDB
Apprehension SIDER
Arrhythmia ADReCS
Arrhythmia Supraventricular ADReCS
Aspartate Aminotransferase Increased SIDER
Asthenia ADReCS
Ataxia MetaADEDB
Atrioventricular Block MetaADEDB
Azotaemia ADReCS
Azotemia MetaADEDB
Back Pain ADReCS
Blindness MetaADEDB
Blood Creatinine Decreased ADReCS
Blood Immunoglobulin G Decreased SIDER
Blood Pressure Increased ADReCS
Blood Urea Increased ADReCS
Body Temperature Increased ADReCS
Bradycardia ADReCS
Brain Ischemia MetaADEDB
Breast Mass ADReCS
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiomegaly MetaADEDB
Cardiomyopathy Hypertrophic MetaADEDB
Cataract ADReCS
Cellulitis ADReCS
Cerebral Ischaemia ADReCS
Chest Discomfort ADReCS
Chest Pain ADReCS
Choking ADReCS
Choking Sensation ADReCS
Coma ADReCS
Confusional State ADReCS
Conjunctival Haemorrhage ADReCS
Constipation ADReCS
Convulsion ADReCS
Cough ADReCS
Creatinine Low SIDER
Deafness ADReCS
Decreased Appetite ADReCS
Dermatitis ADReCS
Diabetes Mellitus MetaADEDB
Diabetic Hyperosmolar Coma ADReCS
Diabetic Ketoacidosis ADReCS
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Disease Progression ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Interaction SIDER
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyspnoea ADReCS
Eclampsia MetaADEDB
Edema MetaADEDB
Electrocardiogram Abnormal ADReCS
Electrocardiogram Change SIDER
Eosinophilia ADReCS
Euphoric Mood ADReCS
Exanthema MetaADEDB
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Extravasation ADReCS
Feeling Abnormal ADReCS
Feeling Hot ADReCS
Fluid Retention ADReCS
Flushing ADReCS
Galactorrhoea ADReCS
Gastrointestinal Pain ADReCS
Gingival Hypertrophy MetaADEDB
Glycogen Storage Disease MetaADEDB
Glycosuria ADReCS
Gout ADReCS
Gout Acute ADReCS
Haematuria ADReCS
Haemoglobin ADReCS
Haemoglobin Decreased ADReCS
Haemorrhage ADReCS
Headache ADReCS
Hearing Impaired ADReCS
Heart Arrest MetaADEDB
Heart Block MetaADEDB
Heart Failure MetaADEDB
Hemiplegia MetaADEDB
Herpes Nos SIDER
Herpes Virus Infection ADReCS
Hirsutism ADReCS
Hyperalgesia MetaADEDB
Hyperglycaemia ADReCS
Hyperglycemia MetaADEDB
Hyperglycemic Hyperosmolar Nonketotic Coma MetaADEDB
Hyperhidrosis ADReCS
Hyperinsulinism MetaADEDB
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hypertension Malignant MetaADEDB
Hypertension Pregnancy-Induced MetaADEDB
Hypertension Pulmonary MetaADEDB
Hypertrichosis MetaADEDB
Hypertrophy ADReCS
Hyperuricemia MetaADEDB
Hypoaesthesia ADReCS
Hypoglycemia MetaADEDB
Hypoglycemia Leucine-Induced MetaADEDB
Hypotension ADReCS
Ileus ADReCS
Ill-Defined Disorder ADReCS
Immunoglobulin G Low SIDER
Infarction ADReCS
Infection ADReCS
Infection Susceptibility Increased ADReCS
Injection Site Phlebitis ADReCS
Insomnia ADReCS
Ischaemia ADReCS
Ketoacidosis ADReCS
Lacrimation SIDER
Lacrimation Increased ADReCS
Laryngomalacia MetaADEDB
Lethargy ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Lightheadedness SIDER
Loss Of Consciousness ADReCS
Lymphadenopathy ADReCS
Malaise ADReCS
Mass ADReCS
Movement Disorders MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Myocardial Ischemia MetaADEDB
Nausea ADReCS
Necrosis ADReCS
Nephrotic Syndrome ADReCS
Nerve Degeneration MetaADEDB
Nesidioblastosis MetaADEDB
Neutropenia ADReCS
Nocturia ADReCS
Numbness SIDER
Optic Nerve Disorder ADReCS
Optic Nerve Infarction ADReCS
Optic Neuritis ADReCS
Orthostatic Hypotension ADReCS
Pain ADReCS
Palpitations ADReCS
Pancreatic Necrosis ADReCS
Pancreatitis ADReCS
Pancreatitis Acute ADReCS
Papilloedema ADReCS
Paraesthesia ADReCS
Paralysis ADReCS
Parkinsonian Disorders MetaADEDB
Parotid Gland Enlargement ADReCS
Parotid Swelling SIDER
Persistent Hyperinsulinemia Hypoglycemia Of Infancy MetaADEDB
Phlebitis ADReCS
Polyneuritis ADReCS
Polyneuropathy ADReCS
Preeclamptic Toxemia MetaADEDB
Pruritus ADReCS
Purpura ADReCS
Pyrexia ADReCS
Rash ADReCS
Reperfusion Injury MetaADEDB
Respiratory Insufficiency MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Scotoma ADReCS
Scotoma Annular SIDER
Sensory Loss ADReCS
Shock ADReCS
Somnolence ADReCS
Subconjunctival Hemorrhage SIDER
Sudden Hearing Loss ADReCS
Supraventricular Tachycardia ADReCS
Sweating SIDER
Swelling ADReCS
Tachycardia ADReCS
Thrombocytopenia ADReCS
Vascular Purpura ADReCS
Vasodilation Procedure ADReCS
Vein Pain ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Water Retention SIDER
Weakness SIDER

InAADR: Drug-Protein-ADRs database