InAADR

Drug Information

Drug Name: Dexrazoxane (24584-09-6)
PubChem ID: 71384
SMILES: C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
InchiKey: BMKDZUISNHGIBY-ZETCQYMHSA-N
Therapeutic Category: Antineoplastic Agents, Cardiotonic Agents, Cardiovascular Agents, Enzyme Inhibitors, Protective Agents, Topoisomerase II Inhibitors, Topoisomerase Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 268.273
LogP: -2.7083
Ring Count: 0
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 98.82

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abdominal Symptom MetaADEDB
Acidosis MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Adenopathy MetaADEDB
Adh Inappropriate MetaADEDB
Adrenal Neoplasm MetaADEDB
Afib MetaADEDB
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Agraphia MetaADEDB
Alanine Aminotransferase Increased SIDER
Alopecia ADReCS
Anaemia ADReCS
Anaemia Hypochromic MetaADEDB
Angiopathy ADReCS
Angioplasty MetaADEDB
Anorexia ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aspartate Aminotransferase Increased SIDER
Asthenia ADReCS
Ataxia MetaADEDB
Aura MetaADEDB
Automatism MetaADEDB
Bacterial Sepsis MetaADEDB
Bacterial Toxaemia MetaADEDB
Bilirubin Abnormal ADReCS
Blepharospasm MetaADEDB
Blood Alkaline Phosphatase Abnormal ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Bilirubin Abnormal ADReCS
Blood Bilirubin Increased ADReCS
Blood Calcium MetaADEDB
Blood Creatinine Abnormal ADReCS
Blood Creatinine Increased ADReCS
Blood Disorder MetaADEDB
Blood Lactate Dehydrogenase Increased ADReCS
Blood Sodium MetaADEDB
Blood Urea Abnormal ADReCS
Body Temperature Increased ADReCS
Bone Marrow Failure ADReCS
Brain Scan Abnormal MetaADEDB
Burkitt Lymphoma MetaADEDB
Ca++ Increased SIDER
Carcinoembryonic Antigen Increased MetaADEDB
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Failure Acute MetaADEDB
Cardiac Failure Congestive ADReCS
Cardiac Ventricular Disorder MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Disorder MetaADEDB
Colitis Ischaemic MetaADEDB
Coma MetaADEDB
Connective Tissue Disorder SIDER
Constipation ADReCS
Cough ADReCS
Coughing Blood MetaADEDB
Creatinine Increased SIDER
Decreased Appetite ADReCS
Dehydration MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Device Related Infection MetaADEDB
Diarrhoea ADReCS
Dihydropyrimidine Dehydrogenase Deficiency MetaADEDB
Discomfort ADReCS
Disorder Lung MetaADEDB
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Administration Error MetaADEDB
Dry Mouth PROTECT
Dysphagia ADReCS
Dyspnoea ADReCS
Encephalitis MetaADEDB
Encephalopathy MetaADEDB
Encephalopathy Hypertensive MetaADEDB
Epstein-Barr Viraemia MetaADEDB
Epstein-Barr Virus Associated Lymphoproliferative Disorder MetaADEDB
Erythema ADReCS
Excessive Eye Blinking MetaADEDB
Extravasation ADReCS
Fanconi Syndrome MetaADEDB
Fatigue ADReCS
Febrile Neutropenia ADReCS
Feeling Abnormal ADReCS
Gangrene MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Globulinuria MetaADEDB
Glucose Urine MetaADEDB
Graft Infection MetaADEDB
Granulocytopenia ADReCS
Haemoglobin ADReCS
Haemoglobin Decreased ADReCS
Haemorrhage ADReCS
Headache ADReCS
Hepatic Enzyme Increased PROTECT
Hepatic Function Abnormal ADReCS
Hodgkin Disease MetaADEDB
Hypercalcaemia ADReCS
Hypercreatininaemia MetaADEDB
Hyperventilation MetaADEDB
Hypokalaemia MetaADEDB
Hyponatraemia ADReCS
Hypophosphataemia MetaADEDB
Hypothyroid MetaADEDB
Hypotonia MetaADEDB
Ill-Defined Disorder ADReCS
Infection ADReCS
Infestation SIDER
Infestation Nos SIDER
Influenza Like Illness MetaADEDB
Infusion Site Extravasation MetaADEDB
Injection Site Erythema PROTECT
Injection Site Induration PROTECT
Injection Site Pain ADReCS
Injection Site Phlebitis ADReCS
Injection Site Streaking ADReCS
Injection Site Swelling PROTECT
Insomnia ADReCS
Intracranial Tumour Haemorrhage MetaADEDB
Kidney Failure MetaADEDB
Lactic Dehydrogenase Activity Increased SIDER
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Lymphoproliferative Disorder MetaADEDB
Malaise ADReCS
Mediastinal Disorder SIDER
Mental Disorder SIDER
Multifocal Leukoencephalopathy MetaADEDB
Muscle Necrosis MetaADEDB
Myalgia PROTECT
Myelosuppression SIDER
Myotonia MetaADEDB
Nausea ADReCS
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neurotoxicity ADReCS
Neutropenia ADReCS
Neutropenic Infection PROTECT
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophagitis ADReCS
Pain ADReCS
Pain During Injection SIDER
Pancreatic Enzymes Increased MetaADEDB
Pancytopenia ADReCS
Peripheral Ischaemia MetaADEDB
Phlebitis ADReCS
Phosphatase Alkaline Increased SIDER
Platelet Count Decreased ADReCS
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia ADReCS
Post Procedural Infection ADReCS
Postoperative Infection SIDER
Pruritus PROTECT
Psychoses MetaADEDB
Pulmonary Hypertension MetaADEDB
Pyrexia ADReCS
Recall Phenomenon ADReCS
Renal Impairment MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Rate Increased MetaADEDB
Reticulocyte Count Decreased MetaADEDB
Retinoic Acid Syndrome MetaADEDB
Sensory Loss PROTECT
Sepsis ADReCS
Sepsis Syndrome MetaADEDB
Skin Reaction ADReCS
Sodium Decreased SIDER
Somnolence PROTECT
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Staring MetaADEDB
Stomatitis ADReCS
Syncope PROTECT
Thrombocytopenia ADReCS
Thrombophlebitis Superficial PROTECT
Transaminases Increased MetaADEDB
Tremor PROTECT
Urticaria ADReCS
Vaginal Haemorrhage PROTECT
Venous Thrombosis Limb PROTECT
Viral Myositis MetaADEDB
Vomiting ADReCS
Weight Decreased PROTECT
White Blood Cell Count Decreased SIDER
Wound Complication PROTECT

InAADR: Drug-Protein-ADRs database