InAADR

Drug Information

Drug Name: Dexmedetomidine (113775-47-6)
PubChem ID: 5311068
SMILES: CC1=C(C(=CC=C1)[C@H](C)C2=CN=CN2)C
InchiKey: CUHVIMMYOGQXCV-NSHDSACASA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Agonists, Adrenergic alpha-2 Receptor Agonists, Adrenergic alpha-Agonists, Analgesics, Central Nervous System Agents, Central Nervous System Depressants, Hypnotics and Sedatives, Neurotransmitter Agents, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 200.285
LogP: 3.17834
Ring Count: 2
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 28.68

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension PROTECT
Abdominal Pain ADReCS
Abnormal Ecg MetaADEDB
Abnormal Vision ADReCS
Acidosis ADReCS
Acute Coronary Syndrome ADReCS
Acute Respiratory Distress Syndrome ADReCS
Agitation ADReCS
Alanine Aminotransferase Increased ADReCS
Alveolitis Fibrosing MetaADEDB
Anaemia ADReCS
Anoxic Encephalopathy MetaADEDB
Anxiety ADReCS
Apnea MetaADEDB
Apnoea ADReCS
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Abnormal ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Ataxia MetaADEDB
Atelectasis ADReCS
Atrial Fibrillation ADReCS
Atrioventricular Block ADReCS
Atrioventricular Block First Degree PROTECT
Atrioventricular Block Second Degree MetaADEDB
Automatism MetaADEDB
Beta 2 Microglobulin Increased MetaADEDB
Block Heart SIDER
Blood Acid Phosphatase Increased ADReCS
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Cholesterol MetaADEDB
Blood Cholesterol Decreased MetaADEDB
Blood Creatinine MetaADEDB
Blood Magnesium Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Fluctuation ADReCS
Blood Urea Increased MetaADEDB
Blood Urea Nitrogen Increased ADReCS
Blood Uric Acid Decreased MetaADEDB
Body Temperature Increased ADReCS
Bradycardia ADReCS
Bradycardia Neonatal PROTECT
Bradypnoea ADReCS
Brain Death MetaADEDB
Brain Herniation MetaADEDB
Bronchospasm ADReCS
Carbon Dioxide Increased ADReCS
Cardiac Arrest ADReCS
Cardiac Disorder ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Index Decreased MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Output Decreased PROTECT
Cardiac Perforation MetaADEDB
Cardiac Procedure Complication MetaADEDB
Cardiac Tamponade MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Central Venous Pressure Increased MetaADEDB
Cerebral Infarct MetaADEDB
Chills ADReCS
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cognition Disorders MetaADEDB
Coma MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Conjunctival Deposit MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coronary Artery Stenosis MetaADEDB
Coughing Blood MetaADEDB
Decubitus Ulcer MetaADEDB
Delirium ADReCS
Depressive Disorder MetaADEDB
Dialysis MetaADEDB
Diarrhoea ADReCS
Diastolic Hypertension ADReCS
Disease Of Liver MetaADEDB
Dizziness ADReCS
Drug Ineffective PROTECT
Dry Mouth ADReCS
Dyspnoea ADReCS
Echolalia MetaADEDB
Eczema MetaADEDB
Effusion ADReCS
Electrocardiogram St Segment Elevation MetaADEDB
Electrocardiogram T Wave Inversion ADReCS
Electromechanical Dissociation MetaADEDB
Enlarged Liver MetaADEDB
Erythema MetaADEDB
Erythroblast Count Increased MetaADEDB
Excessive Salivation MetaADEDB
Extrasystoles ADReCS
Feeling Abnormal ADReCS
Fluid Retention ADReCS
Gamma-Glutamyltransferase Increased ADReCS
Gastrointestinal Pain ADReCS
Generalised Oedema ADReCS
Glossoptosis MetaADEDB
Haemoglobin ADReCS
Haemoglobin Increased MetaADEDB
Haemolysis MetaADEDB
Haemorrhage ADReCS
Hallucination ADReCS
Headache ADReCS
Heart Arrest MetaADEDB
Heart Block MetaADEDB
Heart Rate Increased MetaADEDB
Hepatic Function Abnormal ADReCS
Hyperalgesia MetaADEDB
Hyperbilirubinaemia ADReCS
Hypercapnia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hyperpyrexia ADReCS
Hypertension ADReCS
Hyperthermia ADReCS
Hypoalbuminaemia PROTECT
Hypocalcaemia ADReCS
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hypomagnesaemia ADReCS
Hypotension ADReCS
Hypoventilation ADReCS
Hypovolaemia ADReCS
Hypoxia ADReCS
Illusion ADReCS
Infarction ADReCS
Light Anaesthesia ADReCS
Lipids Increased MetaADEDB
Long Qt Syndrome MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Mediastinitis MetaADEDB
Memory Disorders MetaADEDB
Metabolic Acidosis PROTECT
Metamyelocyte Percentage Increased MetaADEDB
Monocyte Percentage Increased MetaADEDB
Monoplegia MetaADEDB
Moyamoya Disease MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Rigidity MetaADEDB
Myelocyte Present MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischaemia PROTECT
Myocardial Ischemia MetaADEDB
Myoclonus MetaADEDB
Nausea ADReCS
Neonatal Respiratory Distress Syndrome MetaADEDB
Nephrogenic Diabetes Insipidus MetaADEDB
Neuralgia ADReCS
Neuritis ADReCS
Neuroleptic Malignant Syndrome MetaADEDB
Neuropathy Peripheral ADReCS
Nystagmus MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Off Label Use MetaADEDB
Oliguria ADReCS
Overdose MetaADEDB
Pain ADReCS
Pain Postoperative MetaADEDB
Pedal Pulse Absent MetaADEDB
Periorbital Oedema ADReCS
Peritonitis MetaADEDB
Photopsia ADReCS
Photosensitive Dermatitis ADReCS
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Post Procedural Complication MetaADEDB
Post Procedural Haemorrhage ADReCS
Postoperative Complications MetaADEDB
Postoperative Haemorrhage ADReCS
Procedural Complication MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Time MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Psychomotor Agitation MetaADEDB
Pulmonary Congestion ADReCS
Pulmonary Function Test Decreased ADReCS
Pulmonary Oedema ADReCS
Pyrexia ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Respiratory Acidosis ADReCS
Respiratory Depression ADReCS
Respiratory Distress ADReCS
Respiratory Failure ADReCS
Respiratory Insufficiency MetaADEDB
Respiratory Rate Decreased ADReCS
Retinopathy Of Prematurity MetaADEDB
Right Heart Failure MetaADEDB
Rigors SIDER
Sinus Arrest ADReCS
Sinus Tachycardia ADReCS
Sleep Apnea Central MetaADEDB
Speech Disorder ADReCS
Substance Withdrawal Syndrome MetaADEDB
Supraventricular Tachyarrhythmia ADReCS
Supraventricular Tachycardia ADReCS
Sweating SIDER
Systolic Hypertension ADReCS
Tachycardia ADReCS
Thirst ADReCS
Torsade De Pointes MetaADEDB
Total Cholesterol/Hdl Ratio MetaADEDB
Urine Output ADReCS
Urine Output Decreased ADReCS
Vasospasm Intracranial MetaADEDB
Ventricular Arrhythmia ADReCS
Ventricular Fibrillation MetaADEDB
Ventricular Tachycardia ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Wheezing ADReCS
Withdrawal Syndrome PROTECT

InAADR: Drug-Protein-ADRs database