InAADR

Drug Information

Drug Name: Clofazimine (2030-63-9)
PubChem ID: 2794
SMILES: CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl
InchiKey: WDQPAMHFFCXSNU-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Anti-Bacterial Agents, Anti-Infective Agents, Anti-Inflammatory Agents, Antirheumatic Agents, Coloring Agents, Leprostatic Agents, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 473.407
LogP: 7.4898
Ring Count: 3
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 42.21

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Dapsone (80-08-0) Reduce The Anti-Inflammatory Effects Of Clofazimine Antagonistic Not known Possible incompatibility of dapsone with clofazimine in the treatment of patients with erythema nodosum leprosum

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abdominal Pain ADReCS
Acneiform Eruption ADReCS
Agranulocytosis MetaADEDB
Anaemia ADReCS
Anemia Aplastic MetaADEDB
Anemia Hemolytic MetaADEDB
Angiopathy ADReCS
Anorexia ADReCS
Asthenia ADReCS
Bladder Pain ADReCS
Blindness ADReCS
Body Temperature Increased ADReCS
Bone Pain ADReCS
Cheilosis ADReCS
Completed Suicide ADReCS
Constipation ADReCS
Cystitis ADReCS
Cystitis Noninfective ADReCS
Decreased Appetite ADReCS
Dermatitis ADReCS
Dermatitis Acneiform ADReCS
Dermatitis Exfoliative ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Toxicity MetaADEDB
Embolism ADReCS
Embolism Venous ADReCS
Enteritis ADReCS
Eosinophilia ADReCS
Epigastric Pain SIDER
Eruption SIDER
Fatigue ADReCS
Gastrointestinal Haemorrhage ADReCS
Giddiness SIDER
Haemoglobin ADReCS
Haemorrhage ADReCS
Headache ADReCS
Hepatitis ADReCS
Hepatomegaly ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hypokalaemia ADReCS
Hypokalemia MetaADEDB
Ichthyosis ADReCS
Ichthyosis Acquired ADReCS
Infarction ADReCS
Intestinal Obstruction ADReCS
Jaundice ADReCS
Leprosy MetaADEDB
Leprosy Borderline MetaADEDB
Leprosy Lepromatous MetaADEDB
Leprosy Multibacillary MetaADEDB
Lymphadenopathy ADReCS
Nausea ADReCS
Neuralgia ADReCS
Obstruction ADReCS
Oedema ADReCS
Pain ADReCS
Photosensitivity Reaction ADReCS
Phototoxicity ADReCS
Pigmentation SIDER
Pigmentation Disorder ADReCS
Pigmentation Skin SIDER
Pruritus ADReCS
Pyoderma Gangrenosum MetaADEDB
Rash ADReCS
Skin Discolouration ADReCS
Skin Pigmentation ADReCS
Somnolence ADReCS
Splenic Infarction ADReCS
Suicide SIDER
Sweating SIDER
Thromboembolism ADReCS
Vascular Pain SIDER
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weight Decreased ADReCS

InAADR: Drug-Protein-ADRs database