InAADR

Drug Information

Drug Name: Cladribine (4291-63-8)
PubChem ID: 20279
SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(N=C3N)Cl)CO)O
InchiKey: PTOAARAWEBMLNO-KVQBGUIXSA-N
Therapeutic Category: Antineoplastic Agents, Immunologic Factors, Immunosuppressive Agents

Computed Drug Properties

Molecular Weight (dalton): 285.691
LogP: -0.2974
Ring Count: 2
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 119.31

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abnormal Chest Sounds Nos SIDER
Abnormalities Drug-Induced MetaADEDB
Abnormalities Multiple MetaADEDB
Aggression ADReCS
Agranulocytosis MetaADEDB
Alopecia PROTECT
Amyloidosis PROTECT
Anaemia ADReCS
Anemia MetaADEDB
Anemia Aplastic MetaADEDB
Anemia Hemolytic MetaADEDB
Anemia Hemolytic Autoimmune MetaADEDB
Anorexia ADReCS
Anxiety PROTECT
Aplastic Anaemia ADReCS
Arrhythmia ADReCS
Arthralgia ADReCS
Arthritis PROTECT
Asthenia ADReCS
Ataxia PROTECT
Atrial Fibrillation PROTECT
Atrioventricular Block MetaADEDB
Blepharitis PROTECT
Blindness MetaADEDB
Blood Bilirubin Increased ADReCS
Blood Uric Acid Increased ADReCS
Body Temperature Increased ADReCS
Bone Marrow Diseases MetaADEDB
Bone Marrow Failure ADReCS
Bone Pain PROTECT
Breath Sounds Abnormal ADReCS
Cachexia PROTECT
Cardiac Failure PROTECT
Cardiac Murmur PROTECT
Cell Death ADReCS
Cell Transformation Neoplastic MetaADEDB
Cerebrovascular Accident PROTECT
Chills ADReCS
Cholecystitis PROTECT
Confusional State PROTECT
Conjunctivitis PROTECT
Constipation ADReCS
Cough ADReCS
Cytolysis ADReCS
Decreased Appetite ADReCS
Demyelinating Diseases MetaADEDB
Depression PROTECT
Dermatitis ADReCS
Device Damage ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Dysphagia PROTECT
Dyspnea MetaADEDB
Dyspnoea ADReCS
Eosinophilia ADReCS
Epilepsy PROTECT
Epistaxis ADReCS
Erythema ADReCS
Erythema Multiforme MetaADEDB
Extravasation ADReCS
Fatigue ADReCS
Febrile Neutropenia ADReCS
Feeling Abnormal ADReCS
Fetal Resorption MetaADEDB
Fever MetaADEDB
Fibrosis ADReCS
Flatulence PROTECT
Fungal Infection ADReCS
Gastrointestinal Pain ADReCS
Graft Versus Host Disease PROTECT
Guillain-Barre Syndrome MetaADEDB
Haemoglobin ADReCS
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Headache ADReCS
Heart Failure MetaADEDB
Hepatic Failure PROTECT
Hernia MetaADEDB
Herpes Nos SIDER
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hypereosinophilia SIDER
Hyperhidrosis ADReCS
Hyperuricaemia ADReCS
Hypotension PROTECT
Ileus PROTECT
Ill-Defined Disorder ADReCS
Immunosuppression ADReCS
Infection ADReCS
Injection Site Reaction ADReCS
Insomnia ADReCS
Insufficiency Renal SIDER
Interstitial Lung Disease ADReCS
Lethargy PROTECT
Leukemia Hairy Cell MetaADEDB
Leukemia Lymphocytic Chronic B-Cell MetaADEDB
Leukemia Lymphoid MetaADEDB
Leukemia Myeloid MetaADEDB
Leukemia Myeloid Acute MetaADEDB
Lung Neoplasms MetaADEDB
Lymphoma B-Cell MetaADEDB
Lymphoma Large B-Cell Diffuse MetaADEDB
Lymphoma T-Cell Cutaneous MetaADEDB
Lymphopenia ADReCS
Macrocytosis ADReCS
Malaise ADReCS
Microphthalmos MetaADEDB
Mucosal Inflammation PROTECT
Multiple Sclerosis MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myelodysplastic Syndrome ADReCS
Myelosuppression SIDER
Myocardial Ischaemia PROTECT
Nausea ADReCS
Necrolysis Epidermal SIDER
Necrosis MetaADEDB
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Neurotoxicity ADReCS
Neutropenia ADReCS
No Match PROTECT
Obstruction ADReCS
Oedema ADReCS
Opportunistic Infection ADReCS
Pain ADReCS
Pain Of Skin PROTECT
Pancreatic Disorder SIDER
Pancytopenia ADReCS
Paraesthesia PROTECT
Paraparesis ADReCS
Peripheral Nervous System Diseases MetaADEDB
Petechiae ADReCS
Pharyngitis PROTECT
Phlebitis ADReCS
Pneumonia ADReCS
Polyneuropathy ADReCS
Primary Myelofibrosis MetaADEDB
Pruritus ADReCS
Pulmonary Embolism PROTECT
Purpura ADReCS
Pyrexia ADReCS
Quadriparesis ADReCS
Rash ADReCS
Redness SIDER
Renal Failure ADReCS
Renal Failure Acute ADReCS
Second Primary Malignancy SIDER
Sepsis ADReCS
Septicemia SIDER
Somnolence PROTECT
Speech Disorder PROTECT
Spinal Dysraphism MetaADEDB
Stevens-Johnson Syndrome ADReCS
Sweating Increased SIDER
Swelling ADReCS
Systemic Vasculitis MetaADEDB
T-Lymphocytopenia MetaADEDB
Tachycardia ADReCS
Thrombocytopenia ADReCS
Thrombosis ADReCS
Toxic Epidermal Necrolysis ADReCS
Transaminases Increased PROTECT
Tumour Lysis Syndrome ADReCS
Ureteric Obstruction ADReCS
Uric Acid Level Increased SIDER
Urine Output ADReCS
Urticaria ADReCS
Vascular Purpura ADReCS
Vomiting ADReCS
Waldenstrom Macroglobulinemia MetaADEDB
Weakness SIDER

InAADR: Drug-Protein-ADRs database