InAADR

Drug Information

Drug Name: Cefmetazole (56796-20-4)
PubChem ID: 42008
SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O)O
InchiKey: SNBUBQHDYVFSQF-HIFRSBDPSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 471.546
LogP: -0.72832
Ring Count: 1
Hydrogen Bond Acceptor Count: 12
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 163.33

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Warfarin (81-81-2) Bleeding Additive Cephalosporins with an N-methylthiotetrazole side-chain can, like the oral anticoagulants, act as vitamin K antagonists to reduce the production of some blood clotting factors. They can therefore cause bleeding on their own. Influence of cephalosporin antibiotics on blood coagulation and platelet function

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Tenderness MetaADEDB
Abdominal Wound Dehiscence MetaADEDB
Abnormal Vision MetaADEDB
Abscess MetaADEDB
Acute Pancreatitis MetaADEDB
Adenocarcinoma MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Agitated MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Anaemia MetaADEDB
Anaemia Postoperative MetaADEDB
Anal Cancer MetaADEDB
Androgen Deficiency MetaADEDB
Anuria MetaADEDB
Anxiety Disorder MetaADEDB
Aortic Injury MetaADEDB
Apnea MetaADEDB
Appendicitis MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Autoimmune Hepatitis MetaADEDB
Back Ache MetaADEDB
Bacterial Pneumonia MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Beta-D-Glucan Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased MetaADEDB
Bradycardia MetaADEDB
Brain Stem Haemorrhage MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cholecystitis MetaADEDB
Chronic Kidney Disease MetaADEDB
Cold Extremities MetaADEDB
Colostomy MetaADEDB
Continuous Haemodiafiltration MetaADEDB
Convulsion MetaADEDB
Cross Infection MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Deafness Neurosensory MetaADEDB
Delusion MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Device Related Infection MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Dialysis Device Complication MetaADEDB
Disease Of Liver MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Drug Hypersensitivity MetaADEDB
Duodenal Ulcer MetaADEDB
Dyspnea Exertional MetaADEDB
Emesis MetaADEDB
Endocarditis Bacterial MetaADEDB
Engraftment Syndrome MetaADEDB
Enteritis Infectious MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epilepsy MetaADEDB
Escherichia Coli Infections MetaADEDB
Extrasystoles Ventricular MetaADEDB
Faeces Discoloured MetaADEDB
Feeling Cold MetaADEDB
Fibrin D Dimer MetaADEDB
Fibrin Degradation Products Increased MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Ulcer MetaADEDB
Gastroenteritis Bacterial MetaADEDB
Gastrointestinal Bleed MetaADEDB
Globulinuria MetaADEDB
Granulocyte Count Decreased MetaADEDB
Haematemesis MetaADEDB
Haematochezia MetaADEDB
Hearing Aid User MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Haematoma MetaADEDB
Hepatic Rupture MetaADEDB
Hepatitis Acute MetaADEDB
Hepatitis C MetaADEDB
Hepatitis C Rna MetaADEDB
Hepatocellular Damage MetaADEDB
Herpes Zoster MetaADEDB
High Blood Pressure MetaADEDB
Hypoaesthesia MetaADEDB
Hypokalaemia MetaADEDB
Hypoproteinaemia MetaADEDB
Hypothyroid MetaADEDB
Ild MetaADEDB
Ileostomy MetaADEDB
Intestinal Anastomosis MetaADEDB
Intestinal Perforation MetaADEDB
Intestinal Resection MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intracardiac Thrombus MetaADEDB
Kidney Failure MetaADEDB
Kidney Tubular Necrosis Acute MetaADEDB
Leukopenia Neonatal MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Meningitis Bacterial MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Liver MetaADEDB
Micturition Urgency MetaADEDB
Muscle Necrosis MetaADEDB
Myoclonus MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Obstructive Airways Disorder MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oral Intake Reduced MetaADEDB
Pallor MetaADEDB
Peripancreatic Fluid Collection MetaADEDB
Perirectal Abscess MetaADEDB
Peritoneal Adhesions MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Post Procedural Complication MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Infection MetaADEDB
Proctocolectomy MetaADEDB
Protein Total Decreased MetaADEDB
Proteinuria MetaADEDB
Pus In Stool MetaADEDB
Renal Amyloidosis MetaADEDB
Reversible Posterior Leukoencephalopathy Syndrome MetaADEDB
Rhabdomyolysis MetaADEDB
Sensory Disturbance MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Shock Haemorrhagic MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Speech Disorder MetaADEDB
Speech Disorder Developmental MetaADEDB
Spinal Compression Fracture MetaADEDB
Staphylococcal Infections MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Suture Rupture MetaADEDB
Tachycardia Ventricular MetaADEDB
Tracheo-Oesophageal Fistula MetaADEDB
Traumatic Liver Injury MetaADEDB
Trichosporon Infection MetaADEDB
Tubulointerstitial Nephritis MetaADEDB
Upper Gastrointestinal Bleeding MetaADEDB
Urine Output Increased MetaADEDB
Vagus Nerve Disorder MetaADEDB
Vena Cava Thrombosis MetaADEDB

InAADR: Drug-Protein-ADRs database