| Drug Name: | interferon gamma (CASNA00101) |
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This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Apoptosis | BAX protein (Q07815) | NO/ONOO(-)-mediated apoptosis was associated with increased expression of Bax with no change in Bcl-2 mRNA abundance [ ADR Type 2 ] | Parsing the effects of nitric oxide, S-nitrosothiols, and peroxynitrite on inducible nitric oxide synthase-dependent cardiac myocyte apoptosis |
| Excitotoxic Mechanisms Of Injury | NMDA receptor-regulated protein 1 (Q8TCU5) | NO acts directly upon immature neurones but indirectly@ via NMDA receptors@ on more mature neurones@showing a complex interaction between inflammatory and excitotoxic mechanisms of injury in mature neurones [ ADR Type 2 ] | A Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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