InAADR

Drug Information

Drug Name: Buspirone (36505-84-7)
PubChem ID: 2477
SMILES: C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4
InchiKey: QWCRAEMEVRGPNT-UHFFFAOYSA-N
Therapeutic Category: Anti-Anxiety Agents, Central Nervous System Agents, Central Nervous System Depressants, Neurotransmitter Agents, Psychotropic Drugs, Serotonin Agents, Serotonin Receptor Agonists, Tranquilizing Agents

Computed Drug Properties

Molecular Weight (dalton): 385.512
LogP: 2.0882
Ring Count: 1
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 69.64

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distress ADReCS
Abdominal Pain MetaADEDB
Abnormal Behaviour MetaADEDB
Abnormal Dreams ADReCS
Abnormal Ecg MetaADEDB
Abnormal Eeg MetaADEDB
Abnormal Sensation In Eye ADReCS
Abscess MetaADEDB
Abuse MetaADEDB
Accident MetaADEDB
Acetonaemia MetaADEDB
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Acne ADReCS
Activities Of Daily Living Impaired MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Pancreatitis MetaADEDB
Adenopathy MetaADEDB
Adhesiolysis MetaADEDB
Administration Site Pain MetaADEDB
Adnexa Uteri Mass MetaADEDB
Adnexitis MetaADEDB
Adrenal Disorder MetaADEDB
Adverse Drug Reaction ADReCS
Adverse Event MetaADEDB
Affect Lability ADReCS
Agitation ADReCS
Agraphia MetaADEDB
Akathisia ADReCS
Akathisia Drug-Induced MetaADEDB
Alcohol Abuse ADReCS
Alcoholic Intoxication MetaADEDB
Allergic Reaction ADReCS
Alopecia ADReCS
Alpha Haemolytic Streptococcal Infection MetaADEDB
Altered State Of Consciousness ADReCS
Amenorrhoea ADReCS
Amentia MetaADEDB
Amnesia MetaADEDB
Anaemia MetaADEDB
Androgen Deficiency MetaADEDB
Anger ADReCS
Angina MetaADEDB
Angioedema ADReCS
Angiopathy MetaADEDB
Anorexia ADReCS
Anxiety MetaADEDB
Anxiety Disorders MetaADEDB
Aortic Disorder MetaADEDB
Aphonia ADReCS
Apnea MetaADEDB
Apoplexy MetaADEDB
Appetite Disorder MetaADEDB
Application Site Erythema MetaADEDB
Application Site Pruritus MetaADEDB
Application Site Vesicles MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Aspiration Pleural Cavity MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Ataxia ADReCS
Atelectasis MetaADEDB
Atrophy MetaADEDB
Attempted Suicide MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Aura MetaADEDB
Autistic Disorder MetaADEDB
Back Ache MetaADEDB
Back Disorder MetaADEDB
Back Injury MetaADEDB
Bacteria Urine MetaADEDB
Basal Ganglia Diseases MetaADEDB
Bedridden MetaADEDB
Biliary Dyskinesia MetaADEDB
Bipolar Disorder MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Blindness Cortical MetaADEDB
Blister ADReCS
Blood Chloride Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood In Urine MetaADEDB
Blood Magnesium MetaADEDB
Blood Ph Increased MetaADEDB
Blood Potassium MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Testosterone Decreased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blurred Vision MetaADEDB
Body Height Decreased MetaADEDB
Body Temperature Increased ADReCS
Bone Scan Abnormal MetaADEDB
Bone Spur MetaADEDB
Bradycardia ADReCS
Bradypnoea MetaADEDB
Brain Scan Abnormal MetaADEDB
Breast Cancer MetaADEDB
Breast Enlargement MetaADEDB
Breast Lump Removal MetaADEDB
Breast Microcalcification MetaADEDB
Breast Pain MetaADEDB
Breast Tenderness MetaADEDB
Breath Sounds MetaADEDB
Bronchitis MetaADEDB
Bruxism MetaADEDB
Bundle Branch Block Right MetaADEDB
Burkitt Lymphoma MetaADEDB
Burn Oesophageal MetaADEDB
Burning Tongue SIDER
Calculus Ureteric MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardio-Respiratory Arrest MetaADEDB
Cardiomyopathy ADReCS
Carotid Artery Disease MetaADEDB
Carpal Tunnel MetaADEDB
Cartilage Development Disorder MetaADEDB
Catalepsy MetaADEDB
Cataract MetaADEDB
Catatonia MetaADEDB
Catheter Related Infection MetaADEDB
Cellulitis MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Infarct MetaADEDB
Cerebrovascular Accident ADReCS
Cervicalgia MetaADEDB
Cervicobrachial Syndrome MetaADEDB
Chest Pain ADReCS
Chest X-Ray Abnormal MetaADEDB
Chills ADReCS
Choking MetaADEDB
Choking Sensation MetaADEDB
Cholecystectomies MetaADEDB
Chronic Fatigue Syndrome MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Claustrophobia ADReCS
Clostridial Infection MetaADEDB
Clostridium Colitis MetaADEDB
Clotting MetaADEDB
Coarctation Of The Aorta MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cognitive Deterioration MetaADEDB
Cognitive Disorder MetaADEDB
Cogwheel Rigidity ADReCS
Cold Intolerance SIDER
Cold Sweat ADReCS
Colectomy Partial MetaADEDB
Colitis Ischaemic MetaADEDB
Colpitis MetaADEDB
Coma MetaADEDB
Computerised Tomogram Abdomen Abnormal MetaADEDB
Confabulation MetaADEDB
Confusion MetaADEDB
Confusional State ADReCS
Conjunctival Abrasion MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Contact Dermatitis MetaADEDB
Contusion ADReCS
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Coordination Abnormal ADReCS
Cough MetaADEDB
Cramp Muscle SIDER
Csf Test Abnormal MetaADEDB
Deafness MetaADEDB
Deafness Traumatic ADReCS
Debridement MetaADEDB
Decreased Appetite ADReCS
Decreased Interest ADReCS
Decreased Libido MetaADEDB
Deep Vein Thromboses MetaADEDB
Demyelination MetaADEDB
Dental Pain MetaADEDB
Depersonalisation ADReCS
Depressed Level Of Consciousness ADReCS
Depressed Mood MetaADEDB
Depression ADReCS
Depressive Disorder MetaADEDB
Depressive Disorder Major MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Complication MetaADEDB
Diabetic Foot MetaADEDB
Diabetic Foot Infection MetaADEDB
Diabetic Hyperosmolar Coma MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Difficulty In Walking MetaADEDB
Dilatation Atrial MetaADEDB
Discomfort ADReCS
Disorder Lung MetaADEDB
Disorders Of Excessive Somnolence MetaADEDB
Dissociative Disorder ADReCS
Distress Gastrointestinal SIDER
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Addict MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Drug Intolerance MetaADEDB
Drug Withdrawal MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Mouth ADReCS
Dry Skin ADReCS
Dysarthria ADReCS
Dysgeusia ADReCS
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyskinesias MetaADEDB
Dysmenorrhea MetaADEDB
Dyspepsia MetaADEDB
Dysphoria ADReCS
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Dystonia ADReCS
Dystonic Disorders MetaADEDB
Dystonic Reaction SIDER
Dysuria ADReCS
Ear Ache MetaADEDB
Early Morning Awakening MetaADEDB
Ecchymoses MetaADEDB
Ecchymosis ADReCS
Echocardiogram Abnormal MetaADEDB
Eczema MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Ejaculation Delayed ADReCS
Electrocardiogram Change SIDER
Electrocardiogram Qt Shortened MetaADEDB
Electrocardiogram St Segment Abnormal MetaADEDB
Emesis MetaADEDB
Endometriosis MetaADEDB
Enteritis MetaADEDB
Enuresis ADReCS
Eosinophilia ADReCS
Epilepsy Tonic-Clonic MetaADEDB
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erythema ADReCS
Euphoric Mood ADReCS
Excitement SIDER
Excoriation MetaADEDB
External Ear Infection MetaADEDB
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Extremity Pain MetaADEDB
Eye Irritation ADReCS
Eye Pain ADReCS
Eye Pruritus ADReCS
Eye Rolling MetaADEDB
Face Oedema ADReCS
Faecal Occult Blood Positive MetaADEDB
Fat Necrosis MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fear ADReCS
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Feeling Of Despair MetaADEDB
Female Reproductive Neoplasm MetaADEDB
Fever MetaADEDB
Fibromyalgia MetaADEDB
Flatulence ADReCS
Flu MetaADEDB
Flushing ADReCS
Furuncle MetaADEDB
Galactorrhoea ADReCS
Gallbladder Injury MetaADEDB
Gallbladder Operation MetaADEDB
Gambling MetaADEDB
Gastric Lavage MetaADEDB
Gastric Ph Decreased MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Disturbance ADReCS
Gastrointestinal Oedema MetaADEDB
Generalised Anxiety Disorder MetaADEDB
Gingival Pain MetaADEDB
Glossodynia ADReCS
Glucose Intolerance MetaADEDB
Haematochezia MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhagic Disorder ADReCS
Hair Colour Changes MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Rate Increased MetaADEDB
Hemiplegia MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatitis B MetaADEDB
Hiccups ADReCS
High Blood Pressure MetaADEDB
Hip Surgery MetaADEDB
Histoplasmosis MetaADEDB
Hodgkin Disease MetaADEDB
Hostility ADReCS
Hot Flash MetaADEDB
Hyperhidrosis MetaADEDB
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hyperventilation ADReCS
Hypoaesthesia ADReCS
Hypogonadism MetaADEDB
Hyponatremia MetaADEDB
Hypotension ADReCS
Hypovolaemia MetaADEDB
Hysterectomy MetaADEDB
Ill-Defined Disorder ADReCS
Impetigo MetaADEDB
Impotence ADReCS
Inappropriate Schedule Of Drug Administration MetaADEDB
Inborn Error Of Metabolism MetaADEDB
Incontinence MetaADEDB
Increased Appetite ADReCS
Increased Platelet Count MetaADEDB
Increased Tendency To Bruise ADReCS
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection Upper Respiratory MetaADEDB
Influenza ADReCS
Ingrowing Nail MetaADEDB
Injection Site Dermatitis MetaADEDB
Injection Site Discolouration MetaADEDB
Inner Ear Disorder ADReCS
Insomnia ADReCS
Intermittent Claudication MetaADEDB
Intermittent Explosive Disorder MetaADEDB
International Normalised Ratio Decreased MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intestinal Functional Disorder ADReCS
Intra-Uterine Contraceptive Device Insertion MetaADEDB
Irritable Bowel Syndrome ADReCS
Ischias MetaADEDB
Jaw Operation MetaADEDB
Joint Injury MetaADEDB
Keratitis Sicca MetaADEDB
Lacrimation Increased MetaADEDB
Lethargy MetaADEDB
Leukopenia ADReCS
Libido Disorder ADReCS
Libido Increased ADReCS
Life Support MetaADEDB
Limb Discomfort MetaADEDB
Limb Injury MetaADEDB
Limb Operation MetaADEDB
Loose Tooth MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lung Consolidation MetaADEDB
Lung Neoplasm MetaADEDB
Lupus Pneumonitis MetaADEDB
Major Depression MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Memory Impairment ADReCS
Meniscus Lesion MetaADEDB
Menstruation Irregular ADReCS
Mental Disability ADReCS
Metabolic Syndrome MetaADEDB
Metrorrhagia ADReCS
Middle Ear Inflammation MetaADEDB
Migraine MetaADEDB
Miosis MetaADEDB
Mitral Valve Prolapse MetaADEDB
Mononeuritis MetaADEDB
Mood Altered MetaADEDB
Mood Swings ADReCS
Movement Disorders MetaADEDB
Movements Involuntary SIDER
Mucous Stools MetaADEDB
Multiple Fractures MetaADEDB
Multiple Sclerosis MetaADEDB
Muscle Rigidity ADReCS
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Mydriasis MetaADEDB
Myocardial Infarction ADReCS
Myoclonus MetaADEDB
Nail Disorder ADReCS
Nail Thinning SIDER
Nail Tinea MetaADEDB
Nasal Congestion ADReCS
Nasal Sinus Congestion MetaADEDB
Nausea ADReCS
Neck Stiffness ADReCS
Nephrolithiasis MetaADEDB
Nervous System Disorder ADReCS
Nervousness ADReCS
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
Nicotine Dependence MetaADEDB
Nightmare ADReCS
Nocturia ADReCS
Nuchal Rigidity ADReCS
Numbness SIDER
Obesity Surgery MetaADEDB
Obsessive-Compulsive Disorder MetaADEDB
Ocular Hyperaemia ADReCS
Oedema ADReCS
Oedema Mouth MetaADEDB
Oophorectomy Bilateral MetaADEDB
Optic Disc Edema MetaADEDB
Optic Neuropathy MetaADEDB
Oral Fungal Infection MetaADEDB
Oral Herpes MetaADEDB
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Osteoarthritis ADReCS
Osteolysis MetaADEDB
Osteopenia MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain Pelvic MetaADEDB
Palpitation MetaADEDB
Palpitations ADReCS
Pancreatic Insufficiency MetaADEDB
Pancreatitis MetaADEDB
Pancreatitis Chronic MetaADEDB
Panic Disorder MetaADEDB
Paraesthesia ADReCS
Paresthesia MetaADEDB
Parkinson Disease Secondary MetaADEDB
Parkinsonian Disorders MetaADEDB
Parkinsonism ADReCS
Parosmia ADReCS
Pco2 Decreased MetaADEDB
Pelvic Inflammatory Disease ADReCS
Pelvic Peritoneal Adhesions MetaADEDB
Pericarditis MetaADEDB
Pericarditis Lupus MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Personality Disorders MetaADEDB
Photophobia ADReCS
Pneumothorax MetaADEDB
Pollakiuria ADReCS
Polyp Colorectal MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Haematoma MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Presbyopia MetaADEDB
Pressure Of Speech MetaADEDB
Proctalgia MetaADEDB
Proctitis MetaADEDB
Pruritus ADReCS
Psychotic Disorder ADReCS
Psychotic Disorders MetaADEDB
Pulmonary Congestion ADReCS
Purulence MetaADEDB
Pyrexia ADReCS
Radiculitis Brachial MetaADEDB
Rash ADReCS
Rectal Haemorrhage ADReCS
Redness SIDER
Renal Surgery MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Tract Congestion ADReCS
Restless Legs Syndrome ADReCS
Restlessness ADReCS
Retinal Bleeding MetaADEDB
Rhonchi MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Sarcoidosis MetaADEDB
Schizophrenia MetaADEDB
Seizures SIDER
Self-Injurious Ideation MetaADEDB
Semen Volume Decreased MetaADEDB
Sensation Of Heaviness MetaADEDB
Sensory Loss ADReCS
Serotonin Syndrome ADReCS
Sexual Dysfunctions Psychological MetaADEDB
Shift To The Left MetaADEDB
Shock ADReCS
Sinus Bradycardia MetaADEDB
Sinusitis MetaADEDB
Sleep Apnea MetaADEDB
Sleep Bruxism MetaADEDB
Sleep Disorder MetaADEDB
Sleep Initiation And Maintenance Disorders MetaADEDB
Slurred Speech SIDER
Small Intestinal Obstruction MetaADEDB
Somnolence ADReCS
Sore Eye SIDER
Speech Disorder MetaADEDB
Sperm Count Zero MetaADEDB
Spinal Osteoarthritis MetaADEDB
Stress MetaADEDB
Stupor ADReCS
Substance Abuse MetaADEDB
Suicidal Behaviour MetaADEDB
Suicidal Ideation ADReCS
Syncope ADReCS
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Taste Altered SIDER
Tearfulness MetaADEDB
Temperature Intolerance ADReCS
Tenderness ADReCS
Tendinitis MetaADEDB
Tension ADReCS
Thalamic Infarction MetaADEDB
Therapeutic Reaction Time Decreased ADReCS
Thinking Abnormal ADReCS
Throat Sore SIDER
Thrombocytopenia ADReCS
Thyroid Disorder ADReCS
Tinnitus ADReCS
Tobacco Withdrawal Symptoms MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Troponin Increased MetaADEDB
Tunnel Vision ADReCS
Ulcer MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urinary Hesitation ADReCS
Urinary Retention ADReCS
Urinary Tract Inflammation MetaADEDB
Urine Flow Decreased MetaADEDB
Urticaria ADReCS
Vascular Calcification MetaADEDB
Vasospasm MetaADEDB
Vertigo ADReCS
Viral Upper Respiratory Tract Infection MetaADEDB
Vision Blurred ADReCS
Visual Disturbance MetaADEDB
Visual Impairment ADReCS
Vivid Dreams SIDER
Volvulus MetaADEDB
Vomiting ADReCS
Weakness SIDER
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS
Wheeze MetaADEDB
Wound Drainage MetaADEDB
Wound Haemorrhage MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB

InAADR: Drug-Protein-ADRs database