InAADR

Drug Information

Drug Name: Brinzolamide (138890-62-7)
PubChem ID: 68844
SMILES: CCN[C@H]1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC
InchiKey: HCRKCZRJWPKOAR-JTQLQIEISA-N
Therapeutic Category: Carbonic Anhydrase Inhibitors, Enzyme Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 383.517
LogP: 0.0869
Ring Count: 1
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 118.8

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort PROTECT
Abdominal Pain PROTECT
Abnormal Gait MetaADEDB
Abnormal Movements MetaADEDB
Abnormal Sensation In Eye PROTECT
Abnormal Vision MetaADEDB
Acid Reflux MetaADEDB
Acquired Diaphragmatic Eventration MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenocarcinoma MetaADEDB
Adenopathy MetaADEDB
Ageusia PROTECT
Agranulocytoses MetaADEDB
Allergic Reaction ADReCS
Alopecia ADReCS
Amnesia PROTECT
Anaemia MetaADEDB
Anaemia Of Malignant Disease MetaADEDB
Anaesthesia MetaADEDB
Angina Pectoris PROTECT
Anterior Chamber Cell MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Dilatation MetaADEDB
Apathy PROTECT
Arrhythmia PROTECT
Arterial Bypass Operation MetaADEDB
Arthralgia PROTECT
Arthritis Rheumatoid MetaADEDB
Asthenia ADReCS
Asthenopia ADReCS
Asthma PROTECT
Asthmatic Crisis MetaADEDB
Atelectasis MetaADEDB
Back Pain PROTECT
Bacteraemia MetaADEDB
Bacterial Infection MetaADEDB
Bad Breath MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Adenoma MetaADEDB
Biliary Dilatation MetaADEDB
Biopsy Liver Abnormal MetaADEDB
Bladder Cancer MetaADEDB
Blepharitis ADReCS
Blepharoptosis MetaADEDB
Blindness Unilateral MetaADEDB
Blood 125-Dihydroxycholecalciferol Decreased MetaADEDB
Blood Beta-D-Glucan Increased MetaADEDB
Blood Chloride Increased PROTECT
Blood Creatine Phosphokinase Abnormal MetaADEDB
Blood In Urine MetaADEDB
Blood Parathyroid Hormone Increased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Pressure Increased PROTECT
Blood Sodium MetaADEDB
Blurred Vision MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Fracture MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Oedema MetaADEDB
Bone Pain MetaADEDB
Bradycardia PROTECT
Bradypnoea MetaADEDB
Brain Oedema MetaADEDB
Bronchial Hyperactivity MetaADEDB
Bronchial Hyperreactivity PROTECT
Bruise MetaADEDB
Bruxism MetaADEDB
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Abnormal MetaADEDB
Cancer MetaADEDB
Candida Infection MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoid Tumour Of The Small Bowel MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure Chronic MetaADEDB
Cardiac Fibrillation MetaADEDB
Cardio-Respiratory Distress PROTECT
Cardioactive Drug Level Increased MetaADEDB
Cataract MetaADEDB
Cataract Nuclear MetaADEDB
Cellulitis MetaADEDB
Cellulitis Orbital MetaADEDB
Cerebellar Tumour MetaADEDB
Cerebral Artery Stenosis MetaADEDB
Cervicalgia MetaADEDB
Chest Discomfort PROTECT
Chest Infection MetaADEDB
Chest Pain ADReCS
Chest X-Ray Abnormal MetaADEDB
Chill MetaADEDB
Choking Sensation MetaADEDB
Chondrocalcinosis MetaADEDB
Chondromalacia MetaADEDB
Coccydynia MetaADEDB
Collagen Disease MetaADEDB
Condition Aggravated MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctival Hyperaemia PROTECT
Conjunctivitis ADReCS
Conjunctivitis Allergic PROTECT
Constipated MetaADEDB
Corneal Clouding MetaADEDB
Corneal Disorder PROTECT
Corneal Epithelium Defect PROTECT
Corneal Epithelium Disorder MetaADEDB
Corneal Erosion PROTECT
Corneal Oedema PROTECT
Corneal Ulcer MetaADEDB
Coronary Artery Occlusion MetaADEDB
Cough PROTECT
Crackles Lung MetaADEDB
Dehydration MetaADEDB
Delayed Recovery From Anaesthesia MetaADEDB
Demyelination MetaADEDB
Deposit Eye PROTECT
Depressed Mood PROTECT
Depression PROTECT
Dermatitis ADReCS
Detached Retina MetaADEDB
Diabetes Insipidus MetaADEDB
Diabetic Gastroparesis MetaADEDB
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Dizziness ADReCS
Drug Withdrawal MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyslipidaemia MetaADEDB
Dyspepsia ADReCS
Dyspnoea ADReCS
Ear Disorder MetaADEDB
Ear Injury MetaADEDB
Early Morning Awakening MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Endophthalmitis MetaADEDB
Enthesopathy MetaADEDB
Eosinophil Count Increased MetaADEDB
Epistaxis PROTECT
Erectile Dysfunction PROTECT
Erythema PROTECT
Erythema Of Eyelid PROTECT
Extrasystoles MetaADEDB
Eye Allergy PROTECT
Eye Discharge ADReCS
Eye Infection Bacterial MetaADEDB
Eye Infection Staphylococcal MetaADEDB
Eye Inflammation MetaADEDB
Eye Irritation PROTECT
Eye Operation MetaADEDB
Eye Pain ADReCS
Eye Pruritus ADReCS
Eye Swelling PROTECT
Eyelid Disorder PROTECT
Eyelid Margin Crusting ADReCS
Eyelid Oedema PROTECT
Eyelid Retraction MetaADEDB
Eyelids Pruritus PROTECT
Fascitis Plantar MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Feeling Abnormal PROTECT
Feeling Jittery PROTECT
Femur Fracture MetaADEDB
Finger Deformity MetaADEDB
Flatulence PROTECT
Foot Fracture MetaADEDB
Foreign Body In Eye PROTECT
Foreign Body Sensation In Eyes ADReCS
Fracture Treatment MetaADEDB
Fractured Pelvis Nos MetaADEDB
Fractured Sacrum MetaADEDB
Frequent Bowel Movements PROTECT
Gastrointestinal Disorder PROTECT
Gastrointestinal Motility Disorder MetaADEDB
General Physical Health Deterioration MetaADEDB
Gingival Disorder MetaADEDB
Glare PROTECT
Glaucoma MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Gout MetaADEDB
Granuloma MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Haemorrhoids MetaADEDB
Hair Growth Abnormal MetaADEDB
Headache ADReCS
Heart Rate Increased PROTECT
Heart Rate Irregular PROTECT
Helicobacter Infection MetaADEDB
Hepatic Lesion MetaADEDB
Herpes Zoster Ophthalmic MetaADEDB
Hot Flash MetaADEDB
Humerus Fracture MetaADEDB
Hyperaemia ADReCS
Hyperbaric Oxygen Therapy MetaADEDB
Hyperchloraemia MetaADEDB
Hyperhidrosis MetaADEDB
Hypersensitivity ADReCS
Hypertension PROTECT
Hypertonia ADReCS
Hypoaesthesia PROTECT
Hypoaesthesia Eye PROTECT
Hypoaesthesia Oral PROTECT
Hypoalbuminaemia MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypotonia MetaADEDB
Ild MetaADEDB
Induration MetaADEDB
Infection MetaADEDB
Infection Upper Respiratory MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Mass MetaADEDB
Injection Site Pruritus MetaADEDB
Insomnia PROTECT
Internal Fixation Of Fracture MetaADEDB
Intestinal Resection MetaADEDB
Intraocular Pressure Increased PROTECT
Intraocular Pressure Test MetaADEDB
Iritis MetaADEDB
Irritability PROTECT
Jra MetaADEDB
Keratitis ADReCS
Keratoconjunctivitis SIDER
Keratopathy ADReCS
Keratorhexis MetaADEDB
Kidney Failure MetaADEDB
Lacrimation SIDER
Lacrimation Increased ADReCS
Laryngospasm MetaADEDB
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Libido Decreased PROTECT
Light Sensitivity MetaADEDB
Listeria Sepsis MetaADEDB
Liver Function Test Abnormal PROTECT
Loose Tooth MetaADEDB
Lung Consolidation MetaADEDB
Lymphoma MetaADEDB
Macular Hole MetaADEDB
Madarosis PROTECT
Malabsorption MetaADEDB
Malaise PROTECT
Malnourished MetaADEDB
Mean Cell Haemoglobin Increased MetaADEDB
Medication Residue Present PROTECT
Meibomianitis PROTECT
Memory Impairment PROTECT
Menopausal Disorder MetaADEDB
Menopausal Symptoms MetaADEDB
Mental Disorder MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Metastases To Spine MetaADEDB
Metastases To Thorax MetaADEDB
Metastatic Carcinoid Tumour MetaADEDB
Monoparesis MetaADEDB
Motor Dysfunction PROTECT
Muscle Spasms PROTECT
Myalgia PROTECT
Nasal Congestion PROTECT
Nasal Dryness PROTECT
Nasopharyngitis PROTECT
Nausea ADReCS
Nervousness PROTECT
Neuralgia MetaADEDB
Neuroendocrine Tumour MetaADEDB
Nightmare PROTECT
Nocturia MetaADEDB
Obsessive Thoughts MetaADEDB
Ocular Discomfort ADReCS
Ocular Hyperaemia PROTECT
Oedema Peripheral PROTECT
Oesophagitis PROTECT
Optic Atrophy MetaADEDB
Optic Ischaemic Neuropathy MetaADEDB
Optic Nerve Cup/Disc Ratio Increased PROTECT
Optic Nerve Injury MetaADEDB
Oral Polypectomy MetaADEDB
Oral Surgery MetaADEDB
Oropharyngeal Pain PROTECT
Oropharyngeal Spasm MetaADEDB
Orthopnea MetaADEDB
Osteolysis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Osteosclerosis MetaADEDB
Pain ADReCS
Pain In Extremity PROTECT
Pain In Throat MetaADEDB
Palatal Oedema MetaADEDB
Palpitations PROTECT
Pancreatic Insufficiency MetaADEDB
Panophthalmitis MetaADEDB
Paraesthesia PROTECT
Paraesthesia Oral PROTECT
Peroneal Nerve Palsy MetaADEDB
Pharyngeal Inflammation MetaADEDB
Pharyngitis ADReCS
Photophobia PROTECT
Photopsia PROTECT
Physical Disability MetaADEDB
Pleural Effusion MetaADEDB
Pneumococcal Infection MetaADEDB
Pollakiuria PROTECT
Polydactyly MetaADEDB
Prostate Examination Abnormal MetaADEDB
Pruritus ADReCS
Pruritus Generalised PROTECT
Pterygium PROTECT
Punctate Keratitis PROTECT
Pupillary Reflex Impaired MetaADEDB
Rash PROTECT
Rash Maculo-Papular PROTECT
Rectal Polyp MetaADEDB
Red Blood Cell Count Decreased PROTECT
Renal Pain ADReCS
Retinal Vein Occlusion MetaADEDB
Retinoschisis MetaADEDB
Rhinitis ADReCS
Rhinorrhoea PROTECT
Scab ADReCS
Scar MetaADEDB
Scleral Disorder MetaADEDB
Scleral Pigmentation PROTECT
Scleroderma MetaADEDB
Scoliosis MetaADEDB
Scotoma MetaADEDB
Secretion Discharge MetaADEDB
Sensation Of Foreign Body ADReCS
Sinusitis PROTECT
Skin Tightness PROTECT
Sneezing PROTECT
Somnolence PROTECT
Sopor MetaADEDB
Spinal Fracture MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Sticky Skin ADReCS
Stress Fracture MetaADEDB
Subconjunctival Cyst PROTECT
Superior Vena Cava Syndrome MetaADEDB
Synovial Cyst MetaADEDB
Tachycardia PROTECT
Tendon Disorder MetaADEDB
Throat Irritation PROTECT
Tinnitus PROTECT
Toxic Encephalopathy MetaADEDB
Tremor PROTECT
Upper Respiratory Tract Congestion PROTECT
Upper-Airway Cough Syndrome PROTECT
Urethral Obstruction MetaADEDB
Urticaria ADReCS
Vasculitis Cerebral MetaADEDB
Venous Occlusion MetaADEDB
Vertigo PROTECT
Viral Upper Respiratory Tract Infection MetaADEDB
Vision Blurred ADReCS
Visual Acuity Reduced PROTECT
Visual Impairment PROTECT
Vital Dye Staining Cornea Present PROTECT
Vitreous Haemorrhage MetaADEDB
Vocal Cord Disorder MetaADEDB
Vocal Cord Paralysis MetaADEDB
Vomiting PROTECT

InAADR: Drug-Protein-ADRs database