InAADR

Drug Information

Drug Name: Argatroban (74863-84-6)
PubChem ID: 92722
SMILES: C[C@@H]1CCN([C@H](C1)C(=O)O)C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C
InchiKey: KXNPVXPOPUZYGB-IOVMHBDKSA-N
Therapeutic Category: Anticoagulants, Antithrombins, Enzyme Inhibitors, Hematologic Agents, Platelet Aggregation Inhibitors, Protease Inhibitors, Serine Proteinase Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 508.645
LogP: 0.7029
Ring Count: 1
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 5
Total Polar Surface Area: 180.21

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abortion MetaADEDB
Accident MetaADEDB
Accidental Overdose MetaADEDB
Activated Partial Thromboplastin Time Abnormal MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Activated Partial Thromboplastin Time Shortened MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Myocardial Infarction ADReCS
Acute Psychosis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adrenal Disorder MetaADEDB
Afib MetaADEDB
Alanine Aminotransferase Abnormal MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Reaction ADReCS
Allergies MetaADEDB
Amnesia MetaADEDB
Anaphylactic Reaction MetaADEDB
Aneurysm Ruptured MetaADEDB
Angina Pectoris ADReCS
Angina Unstable ADReCS
Angiopathy ADReCS
Anguish SIDER
Anisocoria MetaADEDB
Anxiety ADReCS
Aortic Aneurysm MetaADEDB
Aortic Regurgitation MetaADEDB
Aortic Stenosis ADReCS
Aortic Valve Stenosis ADReCS
Aphthous Stomatitis MetaADEDB
Apoplexy MetaADEDB
Arterial Thrombosis ADReCS
Artery Dissection MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Atrial Fibrillation ADReCS
Atrial Flutter MetaADEDB
Axillary Vein Thrombosis MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Bad Breath MetaADEDB
Bile Duct Obstruction MetaADEDB
Birth Defect MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Fibrinogen MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Body Temperature Increased ADReCS
Bone Cancer Metastatic MetaADEDB
Bone Disorder MetaADEDB
Bone Graft MetaADEDB
Bone Lesion MetaADEDB
Bradycardia ADReCS
Brain Stem Infarction MetaADEDB
Bronchial Haemorrhage MetaADEDB
Bronchitis MetaADEDB
Bronchopneumonia MetaADEDB
Bullous Eruption ADReCS
Burning Sensation Mucosal MetaADEDB
Candida Infection MetaADEDB
Cardiac Arrest ADReCS
Cardiac Fibrillation ADReCS
Cardiac Valve Disease MetaADEDB
Catheter Sepsis MetaADEDB
Catheter Site Haemorrhage MetaADEDB
Cellulitis MetaADEDB
Cerebral Arteriosclerosis MetaADEDB
Cerebral Artery Stenosis MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Ischaemia MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cerebrovascular Accident ADReCS
Cerebrovascular Disorder ADReCS
Cervical Dysplasia MetaADEDB
Chest Pain ADReCS
Chronic Sinusitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Clostridial Infection MetaADEDB
Clotting MetaADEDB
Coagulation Time Abnormal MetaADEDB
Coagulation Time Prolonged MetaADEDB
Congenital Pyelocaliectasis MetaADEDB
Contrast Media Allergy ADReCS
Corneal Oedema MetaADEDB
Coronary Artery Occlusion ADReCS
Coronary Artery Thrombosis ADReCS
Coronary Thrombosis ADReCS
Cough ADReCS
Csf Pressure Increased MetaADEDB
Cyanosis MetaADEDB
Debridement MetaADEDB
Deglutition Disorder MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Device Failure MetaADEDB
Dialysis MetaADEDB
Diarrhoea ADReCS
Disorder Of Globe MetaADEDB
Disseminated Intravascular Coagulation ADReCS
Drug Administration Error MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Drug Resistance MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Dyspnoea ADReCS
Echocardiogram Abnormal MetaADEDB
Ejection Fraction Decreased MetaADEDB
Embolism MetaADEDB
Embolism Pulmonary MetaADEDB
Encephalitis Herpes MetaADEDB
Endocarditis MetaADEDB
Enzyme Abnormality MetaADEDB
Eruption SIDER
Faecal Impaction MetaADEDB
Failure To Thrive MetaADEDB
Fibrin D Dimer MetaADEDB
Fluid Overload MetaADEDB
Foot Amputation MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gangrene MetaADEDB
Gastric Bypass MetaADEDB
Gastric Ulcer Haemorrhage ADReCS
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Ischaemia MetaADEDB
Gastrointestinal Mucosal Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Haemangioma MetaADEDB
Haematemesis ADReCS
Haematocrit Decreased ADReCS
Haematoma ADReCS
Haematuria ADReCS
Haemodynamic Instability MetaADEDB
Haemoglobin ADReCS
Haemoptysis ADReCS
Haemorrhage ADReCS
Haemorrhage Coronary Artery ADReCS
Haemorrhage Intracranial ADReCS
Haemorrhage Rectum MetaADEDB
Haemorrhagic Cerebral Infarction MetaADEDB
Haemorrhagic Disorder ADReCS
Haemorrhagic Hepatic Cyst MetaADEDB
Haemorrhagic Infarction MetaADEDB
Haemorrhagic Transformation Stroke MetaADEDB
Headache ADReCS
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Herpes Zoster Ophthalmic MetaADEDB
Hypersensitivity ADReCS
Hypokalaemia MetaADEDB
Hypokinesia MetaADEDB
Hypotension ADReCS
Hypoxia MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Impetigo MetaADEDB
Incision Site Haemorrhage MetaADEDB
Incorrect Drug Administration Rate MetaADEDB
Infarction ADReCS
Infection ADReCS
Infusion Site Reaction MetaADEDB
Injection Site Haemorrhage ADReCS
International Normalised Ratio Increased MetaADEDB
Ischaemia ADReCS
Ischaemic Cerebral Infarction MetaADEDB
Jugular Vein Thrombosis MetaADEDB
Kidney Function Abnormal ADReCS
Klebsiella Sepsis MetaADEDB
Labile Blood Pressure MetaADEDB
Lacunar Infarction MetaADEDB
Leg Amputation MetaADEDB
Lung Infection Pseudomonal MetaADEDB
Lung Infiltration MetaADEDB
Lyell MetaADEDB
Mouth Bleeding MetaADEDB
Mucosal Haemorrhage MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Necrosis MetaADEDB
Musculoskeletal Pain MetaADEDB
Myelopathy MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Nausea ADReCS
Neumonia MetaADEDB
Neutrophil Count Decreased MetaADEDB
Oedema ADReCS
Oesophageal Varices Haemorrhage MetaADEDB
Operative Haemorrhage MetaADEDB
Osteomyelitis MetaADEDB
Overdose MetaADEDB
Pain ADReCS
Paranoia MetaADEDB
Pedal Pulse Absent MetaADEDB
Pelvic Venous Thrombosis MetaADEDB
Pericardial Effusion MetaADEDB
Pharyngeal Haemorrhage MetaADEDB
Phlebothrombosis MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia ADReCS
Pneumothorax MetaADEDB
Post Thrombotic Syndrome MetaADEDB
Primary Mediastinal Large B-Cell Lymphoma MetaADEDB
Prothrombin Time Abnormal MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Oedema ADReCS
Pyelonephritis MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Rectal Ulcer MetaADEDB
Renal Impairment ADReCS
Renal Vein Thrombosis MetaADEDB
Respiratory Disorder ADReCS
Respiratory Failure MetaADEDB
Retroperitoneal Haemorrhage ADReCS
Seborrhoeic Keratosis MetaADEDB
Sensory Disturbance MetaADEDB
Sepsis ADReCS
Sequestrectomy MetaADEDB
Serratia Sepsis MetaADEDB
Skin Discolouration MetaADEDB
Skin Operation MetaADEDB
Skin Reaction ADReCS
Small Intestinal Obstruction MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subclavian Vein Thrombosis MetaADEDB
Suprapubic Pain MetaADEDB
Tachycardia ADReCS
Therapeutic Response Decreased MetaADEDB
Thoracotomy MetaADEDB
Thrombosis In Device MetaADEDB
Toe Amputation MetaADEDB
Tooth Extraction MetaADEDB
Tracheal Deviation MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urinary Tract Infection ADReCS
Vasodilation SIDER
Vasodilation Procedure ADReCS
Vena Cava Thrombosis MetaADEDB
Venous Occlusion MetaADEDB
Venous Stenosis MetaADEDB
Ventricular Tachycardia ADReCS
Vitamin K Deficiency MetaADEDB
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database