InAADR

Drug Information

Drug Name: Apixaban (503612-47-3)
PubChem ID: 10182969
SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N
InchiKey: QNZCBYKSOIHPEH-UHFFFAOYSA-N
Therapeutic Category: Anticoagulants, Antithrombins, Enzyme Inhibitors, Factor Xa Inhibitors, Hematologic Agents, Protease Inhibitors, Serine Proteinase Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 459.506
LogP: 2.6996
Ring Count: 3
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 110.76

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Gastro Intestinal Bleeding Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abnormal Behaviour MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Vision MetaADEDB
Accidental Overdose MetaADEDB
Acute Kidney Failure MetaADEDB
Afib MetaADEDB
Agraphia MetaADEDB
Alanine Aminotransferase MetaADEDB
Alanine Aminotransferase Abnormal PROTECT
Alanine Aminotransferase Increased PROTECT
Allergic Oedema PROTECT
Anaemia PROTECT
Anaemia Postoperative PROTECT
Anaphylactic Reaction PROTECT
Anticonvulsant Drug Level Increased MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Dissection MetaADEDB
Application Site Haemorrhage PROTECT
Aspartate Aminotransferase Increased PROTECT
Atelectasis MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Bacterial Disease Carrier MetaADEDB
Blood Alkaline Phosphatase Increased PROTECT
Blood Bilirubin Increased PROTECT
Blood In Urine MetaADEDB
Blood Sodium MetaADEDB
Blood Thyroid Stimulating Hormone MetaADEDB
Brain Stem Infarction MetaADEDB
Bronchopneumonia MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiomyopathy MetaADEDB
Cardiopulmonary Failure MetaADEDB
Cartilage Development Disorder MetaADEDB
Catheter Site Haemorrhage PROTECT
Cerebral Atrophy MetaADEDB
Cerebral Haemorrhage PROTECT
Cerebral Infarct MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Cholecystitis Acute MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Colonic Polyp MetaADEDB
Coma MetaADEDB
Conjunctival Haemorrhage PROTECT
Contusion PROTECT
Depressed Level Of Consciousness MetaADEDB
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Withdrawal MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Emotional Disorder MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epistaxis PROTECT
Eye Haemorrhage PROTECT
Gamma-Glutamyltransferase Increased PROTECT
Gastrointestinal Haemorrhage PROTECT
Gastrointestinal Necrosis MetaADEDB
Gilbert Syndrome MetaADEDB
Gingival Bleeding PROTECT
Haematemesis PROTECT
Haematochezia PROTECT
Haematoma PROTECT
Haematuria PROTECT
Haemoptysis PROTECT
Haemorrhage PROTECT
Haemorrhage Intracranial PROTECT
Haemorrhagic Anaemia PROTECT
Haemorrhoidal Haemorrhage PROTECT
Haemothorax MetaADEDB
Hematoma Subdural MetaADEDB
Hemiparesis MetaADEDB
Hepatotoxicity MetaADEDB
Hiccough MetaADEDB
Hypersensitivity PROTECT
Hypotension PROTECT
Hypotension Orthostatic MetaADEDB
Incision Site Haematoma PROTECT
Incision Site Haemorrhage PROTECT
Incorrect Route Of Drug Administration MetaADEDB
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Intentional Drug Misuse MetaADEDB
Intra-Abdominal Haemorrhage PROTECT
Ischaemic Stroke MetaADEDB
Large Intestinal Haemorrhage MetaADEDB
Laryngeal Haemorrhage PROTECT
Limb Discomfort MetaADEDB
Liver Function Test Abnormal PROTECT
Mallory-Weiss Syndrome MetaADEDB
Melaena PROTECT
Mental Status Changes MetaADEDB
Mesenteric Artery Embolism MetaADEDB
Mouth Haemorrhage PROTECT
Muscle Haemorrhage PROTECT
Nausea PROTECT
Near Syncope MetaADEDB
Neoplasia MetaADEDB
Neumonia MetaADEDB
Occult Blood Positive PROTECT
Oropharyngeal Pain MetaADEDB
Pharyngeal Haemorrhage PROTECT
Platelet Count Decreased PROTECT
Polyneuropathy MetaADEDB
Post Procedural Haematoma PROTECT
Post Procedural Haemorrhage PROTECT
Procedural Haemorrhage PROTECT
Procedural Hypotension PROTECT
Psoriasis MetaADEDB
Pulmonary Alveolar Haemorrhage PROTECT
Rash PROTECT
Rectal Haemorrhage PROTECT
Respiratory Tract Haemorrhage PROTECT
Retroperitoneal Haemorrhage PROTECT
Sinus Bradycardia MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal Cord Haemorrhage PROTECT
Spinal Haematoma PROTECT
Subarachnoid Haemorrhage PROTECT
Subdural Haematoma PROTECT
Sudden Death MetaADEDB
Synovial Rupture MetaADEDB
Throat Tightness MetaADEDB
Thrombocytopenia PROTECT
Transaminases Increased PROTECT
Traumatic Haemorrhage PROTECT
Tubulointerstitial Nephritis MetaADEDB
Upper Gastrointestinal Bleeding MetaADEDB
Urethral Haemorrhage PROTECT
Urogenital Haemorrhage PROTECT
Vaginal Haemorrhage PROTECT
Vessel Puncture Site Haematoma PROTECT
Wound Haemorrhage PROTECT
Wound Secretion PROTECT
Wrong Technique In Drug Usage Process MetaADEDB

InAADR: Drug-Protein-ADRs database