InAADR

Drug Information

Drug Name: Amphetamine (300-62-9)
PubChem ID: 3007
SMILES: CC(CC1=CC=CC=C1)N
InchiKey: KWTSXDURSIMDCE-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Uptake Inhibitors, Autonomic Agents, Central Nervous System Agents, Central Nervous System Stimulants, Dopamine Agents, Dopamine Uptake Inhibitors, Membrane Transport Modulators, Neurotransmitter Agents, Neurotransmitter Uptake Inhibitors, Peripheral Nervous System Agents, Sympathomimetics

Computed Drug Properties

Molecular Weight (dalton): 135.21
LogP: 1.5763
Ring Count: 1
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 26.02

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Chlorpromazine (50-53-3) Antagonises The Apetite Supressant Effect Of Amfetamines Antagonistic Not Understood Asystole and bradycardia during dipyridamole stress testing in patients receiving beta blockers
Cocaine (50-36-2) Ischaemic Stroke Additive Not Clear Amphetamine poisoning: effectiveness of chlorpromazine
Furazolidone (67-45-8) Rise In Blood Pressure Antagonistic Amphetamine interacts with furazolidone gradually after 5 to 10 days of use The anti-monoamine oxidase effects of furazolidone

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp SIDER
Abdominal Discomfort MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness MetaADEDB
Abnormal Ecg MetaADEDB
Abnormal Sleep-Related Event MetaADEDB
Abnormalities Drug-Induced MetaADEDB
Abscess MetaADEDB
Abscess Drainage MetaADEDB
Abuse MetaADEDB
Accelerated Hypertension MetaADEDB
Accidental Death MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Injury MetaADEDB
Acute Leukaemia MetaADEDB
Adenitis MetaADEDB
Administration Site Pain MetaADEDB
Adnexitis MetaADEDB
Adrenal Insufficiency MetaADEDB
Adverse Event MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability ADReCS
Aggression ADReCS
Agitation ADReCS
Agitation Postoperative MetaADEDB
Alcohol Consumption MetaADEDB
Alopecia MetaADEDB
Alveolitis MetaADEDB
Amentia MetaADEDB
Amnesia MetaADEDB
Amphetamine-Related Disorders MetaADEDB
Anal Fistula MetaADEDB
Anal Pruritus MetaADEDB
Anaphylactic Shock ADReCS
Anemia MetaADEDB
Aneurysm MetaADEDB
Aneurysm Dissecting MetaADEDB
Aneurysm Ruptured MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Ankle Fracture MetaADEDB
Anomaly Of External Ear Congenital MetaADEDB
Anorexia ADReCS
Anterior Wall Myocardial Infarction MetaADEDB
Anticholinergic Syndrome MetaADEDB
Anxiety ADReCS
Anxiety Disorders MetaADEDB
Aortic Aneurysm MetaADEDB
Appetite Absent SIDER
Application Site Pustules MetaADEDB
Application Site Rash MetaADEDB
Aptyalism MetaADEDB
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteritis MetaADEDB
Asthenia ADReCS
Astrocytoma MetaADEDB
Asystole MetaADEDB
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrophy MetaADEDB
Attention Deficit Disorder With Hyperactivity MetaADEDB
Attention Deficit/Hyperactivity Disorder SIDER
Automatic Bladder MetaADEDB
Benign Intracranial Hypertension MetaADEDB
Biopsy Colon MetaADEDB
Bipolar Disorder MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Pressure Increased ADReCS
Blood Pressure Systolic Increased ADReCS
Body Temperature Increased ADReCS
Bone Spur MetaADEDB
Bradycardia MetaADEDB
Bradypnoea MetaADEDB
Brain Concussion MetaADEDB
Brain Damage MetaADEDB
Brain Damage Chronic MetaADEDB
Brain Diseases MetaADEDB
Brain Injuries MetaADEDB
Brain Ischemia MetaADEDB
Breakthrough Bleeding MetaADEDB
Breast Discharge MetaADEDB
Breast Tenderness MetaADEDB
Bruxism MetaADEDB
Budd-Chiari Syndrome MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoma Of The Colon MetaADEDB
Cardiac Death ADReCS
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathies MetaADEDB
Cardiomyopathy ADReCS
Cardiomyopathy Dilated MetaADEDB
Cardiovascular Abnormalities MetaADEDB
Cardiovascular Diseases MetaADEDB
Carotid Artery Diseases MetaADEDB
Carotidynia MetaADEDB
Catalepsy MetaADEDB
Cataplexy MetaADEDB
Catatonia MetaADEDB
Cellulitis MetaADEDB
Cellulitis Staphylococcal MetaADEDB
Cerebral Hemorrhage MetaADEDB
Cerebral Infarction MetaADEDB
Cerebrovascular Accident ADReCS
Chest Pain ADReCS
Child Behavior Disorders MetaADEDB
Chill MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholecystitis Chronic MetaADEDB
Chorea MetaADEDB
Chromosome 13Q Trisomy MetaADEDB
Chronic Fatigue Syndrome MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cognition Disorders MetaADEDB
Colitis Ischaemic MetaADEDB
Colitis Ischemic MetaADEDB
Colonoscopy MetaADEDB
Coma ADReCS
Completed Suicide MetaADEDB
Computerised Tomogram MetaADEDB
Conduct Disorder MetaADEDB
Confabulation MetaADEDB
Confusion Postoperative MetaADEDB
Confusional State ADReCS
Congenital Nystagmus MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Stenosis MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Corneal Epithelium Disorder MetaADEDB
Coronary Aneurysm MetaADEDB
Coronary Vasospasm MetaADEDB
Cough MetaADEDB
Cramp Muscle SIDER
Crohn Disease MetaADEDB
Cutaneous Ulcer MetaADEDB
Death ADReCS
Death Sudden Cardiac MetaADEDB
Decreased Appetite ADReCS
Delirium ADReCS
Delusion MetaADEDB
Demyelination MetaADEDB
Dental Caries MetaADEDB
Depressive Disorder MetaADEDB
Dermatitis ADReCS
Dermatitis Seborrheic MetaADEDB
Developmental Delay MetaADEDB
Developmental Disabilities MetaADEDB
Device Leakage MetaADEDB
Diabetes Insipidus MetaADEDB
Diaphragmatic Injury MetaADEDB
Diarrhoea ADReCS
Dilatation Ventricular MetaADEDB
Diplopia MetaADEDB
Disease Models Animal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Disturbance In Attention MetaADEDB
Disturbance In Sexual Arousal ADReCS
Diuresis SIDER
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Abuser MetaADEDB
Drug Addict MetaADEDB
Drug Administered At Inappropriate Site MetaADEDB
Drug Administration Error MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Ineffective MetaADEDB
Drug Prescribing Error MetaADEDB
Drug Screen MetaADEDB
Drug Screen Positive MetaADEDB
Drug Toxicity MetaADEDB
Drug Use For Unknown Indication MetaADEDB
Drug Withdrawal MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye MetaADEDB
Dry Mouth ADReCS
Dry Skin MetaADEDB
Ductus Arteriosus Premature Closure MetaADEDB
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyskinesias MetaADEDB
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphoria ADReCS
Dyspnea MetaADEDB
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Dystonia MetaADEDB
Ear Ache MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorders MetaADEDB
Ecchymosis MetaADEDB
Educational Problem MetaADEDB
Ejaculation Delayed MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Electrocardiogram Qt Interval Abnormal MetaADEDB
Encephalomyelitis Autoimmune Experimental MetaADEDB
Encephalopathy MetaADEDB
Eosinophil Count Increased MetaADEDB
Epilepsies Myoclonic MetaADEDB
Epilepsy MetaADEDB
Epstein-Barr Virus Antibody Positive MetaADEDB
Erectile Dysfunction ADReCS
Erythema Migrans MetaADEDB
Erythema Multiforme ADReCS
Esophageal Stenosis MetaADEDB
Esophageal Ulcer MetaADEDB
Euphoric Mood ADReCS
Excessive Sleepiness MetaADEDB
Excoriation MetaADEDB
Exhaustion SIDER
Exposure To Toxic Agent MetaADEDB
Extrasystoles ADReCS
Extravasation Of Diagnostic And Therapeutic Materials MetaADEDB
Eye Abnormalities MetaADEDB
Facial Bones Fracture MetaADEDB
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Guilty MetaADEDB
Female Sexual Dysfunction MetaADEDB
Fetal Death MetaADEDB
Fetal Diseases MetaADEDB
Fever MetaADEDB
Fibula Fracture MetaADEDB
Flatulence MetaADEDB
Flushing ADReCS
Fractured Pelvis Nos MetaADEDB
Furuncle MetaADEDB
Gall Bladder MetaADEDB
Gastroenteritis Bacterial MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Ulcer Haemorrhage MetaADEDB
General Physical Health Deterioration MetaADEDB
General Symptom MetaADEDB
Gliosis MetaADEDB
Groin Abscess MetaADEDB
Growth Disorders MetaADEDB
Growth Of Eyelashes MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhoids MetaADEDB
Hairy Cell Leukaemia MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Head Deformity MetaADEDB
Headache ADReCS
Hearing Loss MetaADEDB
Heart Defects Congenital MetaADEDB
Heart Diseases MetaADEDB
Heart Rate Increased MetaADEDB
Heart Rupture MetaADEDB
Hematoma Subdural Spinal MetaADEDB
Hemianopia MetaADEDB
Hepatitis C MetaADEDB
Hernia Hiatal MetaADEDB
Hernia Repair MetaADEDB
Heroin Dependence MetaADEDB
Hiccough MetaADEDB
Hiv Infections MetaADEDB
Holoprosencephaly MetaADEDB
Homicidal Ideation MetaADEDB
Hyperalgesia MetaADEDB
Hyperhidrosis ADReCS
Hyperkinesis MetaADEDB
Hyperpyrexia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertension Pulmonary MetaADEDB
Hyperthermia ADReCS
Hypokinesia MetaADEDB
Hypopituitarism MetaADEDB
Hypoplastic Right Heart Syndrome MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypothermia MetaADEDB
Hypovolemia MetaADEDB
Ill-Defined Disorder MetaADEDB
Immune Reconstitution Syndrome MetaADEDB
Imprisonment MetaADEDB
Impulse Control Disorders MetaADEDB
Inappropriate Schedule Of Drug Administration MetaADEDB
Incorrect Dose Administered MetaADEDB
Infarction ADReCS
Infarction Middle Cerebral Artery MetaADEDB
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Infectious Mononucleosis MetaADEDB
Inflammatory Bowel Disease MetaADEDB
Influenza Like Illness MetaADEDB
Infusion Site Pain MetaADEDB
Inhibitory Drug Interaction MetaADEDB
Injection Site Mass MetaADEDB
Injection Site Urticaria MetaADEDB
Insomnia ADReCS
Intentional Drug Misuse MetaADEDB
Intentional Misuse MetaADEDB
Intentional Self-Injury MetaADEDB
Intestinal Haemorrhage MetaADEDB
Intracranial Aneurysm MetaADEDB
Intracranial Embolism And Thrombosis MetaADEDB
Intracranial Hemorrhages MetaADEDB
Intussusception MetaADEDB
Irritability ADReCS
Ischaemic Cardiomyopathy MetaADEDB
Kidney Cortex Necrosis MetaADEDB
Lacrimation Increased MetaADEDB
Lacunar Infarction MetaADEDB
Learning Disorders MetaADEDB
Left Atrial Dilatation MetaADEDB
Lethargy ADReCS
Leukoencephalopathy MetaADEDB
Libido Decreased ADReCS
Libido Increased MetaADEDB
Lip Dry MetaADEDB
Liver Diseases MetaADEDB
Localised Infection MetaADEDB
Loss Of Consciousness ADReCS
Lumbar Vertebral Fracture MetaADEDB
Lung Edema MetaADEDB
Malignant Melanoma MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mediastinitis MetaADEDB
Memory Disorders MetaADEDB
Menopausal Disorder MetaADEDB
Mental Disorders MetaADEDB
Mental Impairment MetaADEDB
Metabolic Acidosis MetaADEDB
Mixed Connective Tissue Disease MetaADEDB
Mood Altered MetaADEDB
Mood Swings ADReCS
Motion Sickness MetaADEDB
Motor Tic SIDER
Movement Disorders MetaADEDB
Multi-Organ Disorder MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Injuries MetaADEDB
Multiple Sclerosis MetaADEDB
Muscle Spasms ADReCS
Muscle Spasticity MetaADEDB
Muscle Twitching ADReCS
Musculoskeletal Abnormalities MetaADEDB
Mydriasis MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischemia MetaADEDB
Myocarditis MetaADEDB
Myoclonus MetaADEDB
Myoglobinuria MetaADEDB
Narcolepsy MetaADEDB
Nasal Discomfort MetaADEDB
Nasal Dryness MetaADEDB
Nasal Turbinate Hypertrophy MetaADEDB
Nausea ADReCS
Necrolysis Epidermal SIDER
Neoplasms MetaADEDB
Nephritis Interstitial MetaADEDB
Nephrotic Syndrome MetaADEDB
Nerve Degeneration MetaADEDB
Nervous System Diseases MetaADEDB
Nervousness ADReCS
Neuroaxonal Dystrophies MetaADEDB
Neurobehavioral Manifestations MetaADEDB
Neurodegenerative Diseases MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Neurotic Disorders MetaADEDB
Nicotine Dependence MetaADEDB
Nightmare MetaADEDB
Obsessive Rumination MetaADEDB
Obsessive-Compulsive Disorder MetaADEDB
Optic Disc Edema MetaADEDB
Oral Herpes MetaADEDB
Osteopenia MetaADEDB
Overdose MetaADEDB
Pain ADReCS
Pain Pelvic MetaADEDB
Painful Erection MetaADEDB
Pallor ADReCS
Palpitation MetaADEDB
Palpitations ADReCS
Panic Attack ADReCS
Panic Reaction ADReCS
Paranoid Disorders MetaADEDB
Parathyroid Tumour Benign MetaADEDB
Paresis MetaADEDB
Parkinson Disease MetaADEDB
Partner Stress MetaADEDB
Perceptual Disorders MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Haemorrhage MetaADEDB
Pericarditis MetaADEDB
Peripheral Vascular Diseases MetaADEDB
Perirectal Abscess MetaADEDB
Personality Disorders MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pituitary Haemorrhage MetaADEDB
Plagiocephaly MetaADEDB
Polydactyly MetaADEDB
Polysubstance Abuse MetaADEDB
Polyuria ADReCS
Poor Quality Sleep MetaADEDB
Portal Triaditis MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Infection MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Poverty MetaADEDB
Precancerous Conditions MetaADEDB
Pregnancy Complications MetaADEDB
Premature Birth MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Priapism MetaADEDB
Product Quality Issue MetaADEDB
Product Substitution Issue MetaADEDB
Psychomotor Agitation MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorder ADReCS
Psychotic Disorders MetaADEDB
Psychotic Episode SIDER
Pulmonary Arrest MetaADEDB
Pulmonary Arterial Hypertension MetaADEDB
Pulmonary Edema MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Purpura MetaADEDB
Quadriplegia MetaADEDB
Rash ADReCS
Raynaud Disease MetaADEDB
Removal Of Foreign Body MetaADEDB
Respiratory Distress Syndrome Adult MetaADEDB
Rhabdomyolysis ADReCS
Rhinorrhea MetaADEDB
Rib Fracture MetaADEDB
Road Traffic Accident MetaADEDB
Schizophrenia MetaADEDB
Sedation ADReCS
Seizures SIDER
Self Mutilation MetaADEDB
Self-Medication MetaADEDB
Sexual Dysfunctions Psychological MetaADEDB
Shock ADReCS
Skin Lesion MetaADEDB
Sleep Apnea MetaADEDB
Sleep Deprivation MetaADEDB
Sleep Disorder MetaADEDB
Sleep Disorders MetaADEDB
Sleep Initiation And Maintenance Disorders MetaADEDB
Smoker MetaADEDB
Social Avoidant Behaviour MetaADEDB
Social Problem MetaADEDB
Soft Tissue Injuries MetaADEDB
Somnolence ADReCS
Speech Disorder ADReCS
Spinal Compression Fracture MetaADEDB
Spinal Fracture MetaADEDB
Status Epilepticus MetaADEDB
Stereotypic Movement Disorder MetaADEDB
Sternal Fracture MetaADEDB
Stevens-Johnson Syndrome SIDER
Stomach Ache SIDER
Stress Fracture MetaADEDB
Stroke MetaADEDB
Stupor MetaADEDB
Subarachnoid Hemorrhage MetaADEDB
Subcutaneous Abscess MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Substance-Related Disorders MetaADEDB
Sudden Death ADReCS
Suicidal Behaviour MetaADEDB
Supraventricular Tachycardia MetaADEDB
Sweating SIDER
Syncope ADReCS
Tachycardia ADReCS
Tachyphrenia MetaADEDB
Takotsubo Cardiomyopathy MetaADEDB
Tension ADReCS
Theft MetaADEDB
Therapeutic Response Decreased MetaADEDB
Therapeutic Response Unexpected MetaADEDB
Therapeutic Response Unexpected With Drug Substitution MetaADEDB
Thinking Abnormal MetaADEDB
Throat Tightness MetaADEDB
Thyroid Disease MetaADEDB
Tibia Fracture MetaADEDB
Tic ADReCS
Tic Disorders MetaADEDB
Tobacco User MetaADEDB
Tooth Disorder ADReCS
Tourette Syndrome MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Toxicologic Test Abnormal MetaADEDB
Tremor ADReCS
Troponin T MetaADEDB
Umbilical Cord Abnormality MetaADEDB
Unevaluable Event MetaADEDB
Urinary Retention MetaADEDB
Urinary Tract Infection ADReCS
Urine Output Increased ADReCS
Urticaria ADReCS
Vasculitis MetaADEDB
Vasculitis Central Nervous System MetaADEDB
Vasospasm Intracranial MetaADEDB
Vena Cava Injury MetaADEDB
Ventricular Dysfunction Left MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Hypoplasia MetaADEDB
Viral Infection ADReCS
Viral Pericarditis MetaADEDB
Viral Test Positive MetaADEDB
Viral Upper Respiratory Tract Infection MetaADEDB
Vision Abnormal Neonatal MetaADEDB
Vomiting ADReCS
Waist Circumference Increased MetaADEDB
Weight Abnormal MetaADEDB
Weight Decreased ADReCS
Weight Loss MetaADEDB

InAADR: Drug-Protein-ADRs database