InAADR

Drug Information

Drug Name: Amoxapine (14028-44-5)
PubChem ID: 2170
SMILES: C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
InchiKey: QWGDMFLQWFTERH-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Uptake Inhibitors, Antidepressive Agents, Central Nervous System Agents, Dopamine Agents, Dopamine Antagonists, Membrane Transport Modulators, Neurotransmitter Agents, Neurotransmitter Uptake Inhibitors, Psychotropic Drugs, Serotonin Agents, Serotonin Uptake Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 313.788
LogP: 3.4292
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 36.86

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Abulia MetaADEDB
Accommodation Disorder ADReCS
Acidosis MetaADEDB
Activation Syndrome MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Febrile Neutrophilic Dermatosis MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenitis MetaADEDB
Adh Inappropriate MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Akathisia Drug-Induced MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Alcoholism MetaADEDB
Allergic Alveolitis MetaADEDB
Alopecia ADReCS
Altered State Of Consciousness MetaADEDB
Amentia MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Anorexia ADReCS
Anticholinergic Syndrome MetaADEDB
Antidepressant Drug Level Above Therapeutic MetaADEDB
Antinuclear Antibody MetaADEDB
Anxiety ADReCS
Aortic Dilatation MetaADEDB
Apathy MetaADEDB
Apnea MetaADEDB
Appetite Exaggerated SIDER
Areflexia MetaADEDB
Arrhythmia ADReCS
Arrhythmia Supraventricular ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stent Insertion MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthenospermia MetaADEDB
Ataxia ADReCS
Atelectasis MetaADEDB
Atrial Arrhythmia SIDER
Atrial Fibrillation ADReCS
Atrial Flutter MetaADEDB
Atrioventricular Block ADReCS
Attempted Suicide MetaADEDB
Automatism MetaADEDB
Bacterial Pneumonia MetaADEDB
Basal Ganglia Diseases MetaADEDB
Basedow Disease MetaADEDB
Behcet Syndrome MetaADEDB
Bipolar Disorder MetaADEDB
Black Hairy Tongue MetaADEDB
Bleeding Gums MetaADEDB
Block Heart SIDER
Blood Calcium Increased MetaADEDB
Blood Creatine Phosphokinase Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Glucose Abnormal ADReCS
Blood Glucose Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Osmolarity Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Prolactin Increased ADReCS
Blood Sodium MetaADEDB
Body Temperature Increased ADReCS
Bone Fracture MetaADEDB
Bradyarrhythmia MetaADEDB
Bradypnoea MetaADEDB
Brain Diseases Metabolic MetaADEDB
Brain Injuries MetaADEDB
Brain Oedema MetaADEDB
Breast Enlargement ADReCS
C-Reactive Protein Increased MetaADEDB
Calculus Urinary MetaADEDB
Cancer Pain MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Ventricular Disorder MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathy MetaADEDB
Catalepsy MetaADEDB
Central Nervous System Stimulation MetaADEDB
Central obesity MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cerebration Impaired SIDER
Cerebrovascular Accident ADReCS
Chest X-Ray Abnormal MetaADEDB
Chorea MetaADEDB
Clotting MetaADEDB
Cognition Disorders MetaADEDB
Colitis Ischaemic MetaADEDB
Colitis Pseudomembranous MetaADEDB
Completed Suicide MetaADEDB
Compression Fracture MetaADEDB
Confusional State ADReCS
Congestive Cardiomyopathy MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Csf Neutrophil Count Increased MetaADEDB
Cytomegalovirus Enterocolitis MetaADEDB
Decreased Activity MetaADEDB
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Delusion MetaADEDB
Dental Abscess MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressive Disorder MetaADEDB
Dermatitis ADReCS
Dermatitis Medicamentosa MetaADEDB
Diabetic Acidosis MetaADEDB
Dialysis MetaADEDB
Diarrhoea ADReCS
Disease Recurrence MetaADEDB
Disorder Retinal MetaADEDB
Disorientation ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Distention MetaADEDB
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Fever ADReCS
Drug Toxicity MetaADEDB
Drug Withdrawal Syndrome Neonatal MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dysgeusia ADReCS
Dysgraphia MetaADEDB
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyslalia MetaADEDB
Dyspepsia ADReCS
Dysthymic Disorder MetaADEDB
Dystonia MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Ejaculation Disorder ADReCS
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electroencephalogram Abnormal ADReCS
Empyema MetaADEDB
Enterocolitis Bacterial MetaADEDB
Enterostomy MetaADEDB
Eosinophilia ADReCS
Epigastric Distress SIDER
Epilepsy MetaADEDB
Erectile Dysfunction ADReCS
Eruption MetaADEDB
Erythema Multiforme MetaADEDB
Esophageal Perforation MetaADEDB
Euphoric Mood MetaADEDB
Excitement SIDER
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Eyelid Function Disorder MetaADEDB
Face Pain MetaADEDB
Fatigue ADReCS
Feeding Disorder Neonatal MetaADEDB
Feeling Abnormal ADReCS
Fever MetaADEDB
Flatulence ADReCS
Gait Disorders Neurologic MetaADEDB
Galactorrhea MetaADEDB
Galactorrhoea ADReCS
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Glasgow Coma Scale MetaADEDB
Glossoptosis MetaADEDB
Glycosylated Haemoglobin MetaADEDB
Gynaecomastia MetaADEDB
Haematochezia MetaADEDB
Haemodynamic Instability MetaADEDB
Haemolytic Anaemia MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Heart Failure MetaADEDB
Heart Rate Increased MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Herpes Zoster MetaADEDB
Hypercapnia MetaADEDB
Hypercreatininaemia MetaADEDB
Hyperhidrosis ADReCS
Hyperparathyroidism MetaADEDB
Hypertension ADReCS
Hyperthermia ADReCS
Hypertonia MetaADEDB
Hypertrophy ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Oral MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypomania ADReCS
Hypotension ADReCS
Hypotonia MetaADEDB
Hypoventilation Neonatal MetaADEDB
Ichthyosis MetaADEDB
Ild MetaADEDB
Ileus ADReCS
Ileus Paralytic ADReCS
Impotence ADReCS
Impulse-Control Disorder MetaADEDB
Impulsive Behaviour MetaADEDB
Inappropriate Antidiuretic Hormone Secretion ADReCS
Incoherent MetaADEDB
Increased Appetite ADReCS
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection MetaADEDB
Infection In An Immunocompromised Host MetaADEDB
Inflammatory Bowel Disease MetaADEDB
Insomnia ADReCS
Intention Tremor MetaADEDB
Intentional Misuse MetaADEDB
Intervertebral Disc Compression MetaADEDB
Intestinal Hypomotility MetaADEDB
Intestinal Ulcer MetaADEDB
Jaundice ADReCS
Joint Effusion MetaADEDB
Joint Stiffness MetaADEDB
Laceration MetaADEDB
Lacrimation SIDER
Lacrimation Increased ADReCS
Laryngopharyngitis MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia ADReCS
Libido Decreased ADReCS
Libido Disorder ADReCS
Lipids Abnormal MetaADEDB
Loss Of Consciousness ADReCS
Lower Limb Fracture MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lumbar Vertebral Fracture MetaADEDB
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Macular Oedema MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Malignant Syndrome Nos SIDER
Mechanical Ventilation MetaADEDB
Menstruation Irregular ADReCS
Mental Disability ADReCS
Mental Impairment MetaADEDB
Metastases To Bone Marrow MetaADEDB
Micturition Disorder ADReCS
Movement Disorders MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Myeloma MetaADEDB
Multiple-Drug Resistance MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Rigidity MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Stiffness MetaADEDB
Mydriasis ADReCS
Myocardial Infarction ADReCS
Myoglobin Blood Increased MetaADEDB
Myoglobinuria MetaADEDB
Nasal Congestion ADReCS
Nausea ADReCS
Neonatal Asphyxia MetaADEDB
Nervousness ADReCS
Neuroleptic Malignant Syndrome ADReCS
Nightmare ADReCS
Non-Small Cell Lung Cancer MetaADEDB
Numbness SIDER
Nystagmus MetaADEDB
Occult Blood Positive MetaADEDB
Oedema ADReCS
Oliguria MetaADEDB
Oral Cavity Fistula MetaADEDB
Oral Disorder MetaADEDB
Oral Mucosal Exfoliation MetaADEDB
Overdose MetaADEDB
Pain ADReCS
Palpitation MetaADEDB
Palpitations ADReCS
Pancreatitis ADReCS
Paraesthesia ADReCS
Paresthesia Of Limbs ADReCS
Parkinson MetaADEDB
Parkinsonian Disorders MetaADEDB
Parotid Gland Enlargement ADReCS
Parotid Swelling SIDER
Pedal Pulse Absent MetaADEDB
Petechiae ADReCS
Phobia MetaADEDB
Photosensitivity Reaction ADReCS
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumocystis Carinii Pneumonia MetaADEDB
Pollakiuria ADReCS
Poriomania MetaADEDB
Post Procedural Infection MetaADEDB
Product Taste Abnormal ADReCS
Pruritus ADReCS
Psychiatric Symptom MetaADEDB
Pulmonary Congestion MetaADEDB
Purpura ADReCS
Pyelonephritis MetaADEDB
Qrs Axis Abnormal MetaADEDB
Rash ADReCS
Renal Atrophy MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Restlessness ADReCS
Retinal Depigmentation MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinitis Seasonal MetaADEDB
Rhinorrhea MetaADEDB
Scratch MetaADEDB
Screaming MetaADEDB
Seizures SIDER
Self Injurious Behaviour MetaADEDB
Sensory Loss ADReCS
Sepsis Syndrome MetaADEDB
Sexual Dysfunction Physiological MetaADEDB
Shock ADReCS
Sinus Bradycardia MetaADEDB
Small Intestinal Perforation MetaADEDB
Somnolence ADReCS
Spondylolisthesis MetaADEDB
Sputum Retention MetaADEDB
Status Epilepticus MetaADEDB
Stent Removal MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stomatitis MetaADEDB
Stroke ADReCS
Substance Withdrawal Syndrome MetaADEDB
Surgery MetaADEDB
Surgical Procedure Repeated MetaADEDB
Sweating SIDER
Swelling ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Supraventricular MetaADEDB
Tachycardia Ventricular MetaADEDB
Tardive Dyskinesia ADReCS
Taste Peculiar SIDER
Tearfulness MetaADEDB
Tension ADReCS
Testicular Swelling ADReCS
Thrombocytopenia ADReCS
Tingling Sensation SIDER
Tinnitus ADReCS
Toe Amputation MetaADEDB
Torticollis MetaADEDB
Tremor ADReCS
Tuberculosis Gastrointestinal MetaADEDB
Tumour Marker Increased MetaADEDB
Urinary Retention ADReCS
Urticaria ADReCS
Urticaria Chronic MetaADEDB
Vascular Pseudoaneurysm MetaADEDB
Vascular Purpura ADReCS
Vasculitis ADReCS
Vertigo Positional MetaADEDB
Vision Blurred ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Abnormal ADReCS
Weight Increased ADReCS

InAADR: Drug-Protein-ADRs database