InAADR

Drug Information

Drug Name: Amlodipine (88150-42-9)
PubChem ID: 2162
SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
InchiKey: HTIQEAQVCYTUBX-UHFFFAOYSA-N
Therapeutic Category: Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular Agents, Membrane Transport Modulators, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 408.882
LogP: 2.2663
Ring Count: 1
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 99.88

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Pain ADReCS
Abnormal Behaviour ADReCS
Abnormal Dreams ADReCS
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Vision ADReCS
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accommodation Disorder ADReCS
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Cytolytic Hepatitis ADReCS
Acute Generalised Exanthematous Pustulosis ADReCS
Acute Kidney Injury MetaADEDB
Adenocarcinoma MetaADEDB
Adenoiditis MetaADEDB
Adenopathy MetaADEDB
Adrenal Neoplasm MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Agranulocytosis ADReCS
Akathisia Drug-Induced MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Reaction ADReCS
Allergic Rhinitis MetaADEDB
Allergies MetaADEDB
Allergy To Animal MetaADEDB
Alopecia ADReCS
Alpha 1 Foetoprotein Increased MetaADEDB
Alveolitis MetaADEDB
Amnesia ADReCS
Anaemia MetaADEDB
Angina MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anhidrosis MetaADEDB
Anorexia ADReCS
Anxiety ADReCS
Apathy ADReCS
Aplasia Pure Red Cell MetaADEDB
Appetite Disorder MetaADEDB
Aptyalism MetaADEDB
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriospasm Coronary MetaADEDB
Arthralgia ADReCS
Arthropathy ADReCS
Ascites MetaADEDB
Aseptic Meningitis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asterixis MetaADEDB
Asthenia ADReCS
Astigmatism MetaADEDB
Asystole MetaADEDB
Ataxia ADReCS
Atherosclerosis MetaADEDB
Atrial Fibrillation ADReCS
Atrial Flutter MetaADEDB
Atrioventricular Block MetaADEDB
Atrophy MetaADEDB
Aura MetaADEDB
Axillary Mass MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bacterial Toxaemia MetaADEDB
Basal Ganglia Diseases MetaADEDB
Basophil Count Abnormal MetaADEDB
Benign Neoplasm Of Thyroid Gland MetaADEDB
Bile Duct Obstruction MetaADEDB
Biliary Drainage MetaADEDB
Biliary Tract Disorder MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Biopsy Liver MetaADEDB
Bladder Dilatation MetaADEDB
Bleb MetaADEDB
Blepharoptosis MetaADEDB
Blindness ADReCS
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Chloride Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Potassium MetaADEDB
Blood Pressure Immeasurable MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased MetaADEDB
Bone Neoplasm MetaADEDB
Bradyarrhythmia MetaADEDB
Bradycardia ADReCS
Brain Oedema MetaADEDB
Bronchiolitis MetaADEDB
Bronchitis MetaADEDB
C-Reactive Protein Increased MetaADEDB
Caesarean Section MetaADEDB
Carcinoembryonic Antigen Increased MetaADEDB
Carcinoid Tumour MetaADEDB
Carcinoma MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomegaly MetaADEDB
Cardiovascular Diseases MetaADEDB
Cardiovascular Disorder MetaADEDB
Catalepsy MetaADEDB
Catheterisation Cardiac MetaADEDB
Cauda Equina Syndrome MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerumen Impaction MetaADEDB
Chest Pain ADReCS
Chill MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Cholangitis Acute MetaADEDB
Cholecystitis Acute MetaADEDB
Cholestasis ADReCS
Chromaturia MetaADEDB
Chronic Hepatic Failure MetaADEDB
Chronic Obstructive Pulmonary Disease ADReCS
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Clumsiness MetaADEDB
Cmv Infection MetaADEDB
Coated Tongue MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cold Sweat ADReCS
Colitis Ischaemic MetaADEDB
Color Blindness MetaADEDB
Coma MetaADEDB
Complications Of Transplanted Liver MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Congenital Pyelocaliectasis MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctivitis ADReCS
Constipated MetaADEDB
Constipation ADReCS
Contact Dermatitis MetaADEDB
Convulsion ADReCS
Coronary Artery Disease MetaADEDB
Coronary Disease MetaADEDB
Coronary Restenosis MetaADEDB
Cough ADReCS
Coughing Blood MetaADEDB
Cramp Muscle SIDER
Creatinine Urine Decreased MetaADEDB
Crystalluria ADReCS
Csf Lactate Dehydrogenase Increased MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Protein Increased MetaADEDB
Csf White Blood Cell Count Increased MetaADEDB
Cutaneous Ulcer MetaADEDB
Cyst MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Deafness Neurosensory MetaADEDB
Decreased Appetite ADReCS
Deglutition Disorder MetaADEDB
Delusional Disorder Persecutory Type MetaADEDB
Depersonalisation ADReCS
Depression ADReCS
Dermatitis ADReCS
Dermatitis Exfoliative ADReCS
Dermatomyositis MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus ADReCS
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Eye Disease MetaADEDB
Dialysis MetaADEDB
Dialysis Device Insertion MetaADEDB
Diaphragmatic Disorder MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Diplopia ADReCS
Discomfort ADReCS
Disorder Lung MetaADEDB
Disorder Renal MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Postural ADReCS
Drowsiness MetaADEDB
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dry Skin ADReCS
Dysgeusia ADReCS
Dyslipidaemia MetaADEDB
Dyspareunia MetaADEDB
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysuria ADReCS
Ear Infection MetaADEDB
Ebv Infection MetaADEDB
Echocardiogram Abnormal MetaADEDB
Eczema MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalitis MetaADEDB
Endodontic Procedure MetaADEDB
Enlarged Liver MetaADEDB
Enterococcal Bacteraemia MetaADEDB
Enterococcal Sepsis MetaADEDB
Enuresis MetaADEDB
Eosinophil Count Abnormal MetaADEDB
Eosinophilia ADReCS
Epistaxis ADReCS
Eruption MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Exanthema MetaADEDB
Excess Potassium MetaADEDB
Extrasystoles ADReCS
Extremity Contracture MetaADEDB
Extremity Pain MetaADEDB
Eye Pain ADReCS
Facial Bones Fracture MetaADEDB
Faecaloma MetaADEDB
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Femoral Neck Fracture MetaADEDB
Fib MetaADEDB
Fibrosis MetaADEDB
Flat Affect ADReCS
Flatulence ADReCS
Flushing ADReCS
Food Intolerance MetaADEDB
Fungaemia MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastritis ADReCS
Gastroenteritis MetaADEDB
Gastrointestinal Arteriovenous Malformation MetaADEDB
Gastrointestinal Mucosal Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gingival Hyperplasia ADReCS
Glomerular Filtration Rate Abnormal MetaADEDB
Granulocytosis MetaADEDB
Gynaecomastia ADReCS
Haemangioma MetaADEDB
Haematochezia MetaADEDB
Haemochromatosis MetaADEDB
Haemolytic Anaemia ADReCS
Hair Growth Abnormal MetaADEDB
Hand Fracture MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Diseases MetaADEDB
Hemiparesis MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Neoplasia MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatic Pain MetaADEDB
Hepatitis ADReCS
Hepatoblastoma MetaADEDB
Hepatorenal Failure MetaADEDB
Hiccough MetaADEDB
Hodgkin Disease MetaADEDB
Hot Flush ADReCS
Hyperemia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperpigmentation MetaADEDB
Hyperplasia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertensive SIDER
Hypertensive Heart Disease MetaADEDB
Hypertonia ADReCS
Hypertrichosis MetaADEDB
Hypertrophy MetaADEDB
Hypertrophy Left Ventricular MetaADEDB
Hyperuricemia MetaADEDB
Hypoaesthesia ADReCS
Hypotension ADReCS
Ill-Defined Disorder ADReCS
Immunosuppressant Drug Level Decreased MetaADEDB
Impaired Gastric Emptying MetaADEDB
Impetigo MetaADEDB
Increased Appetite ADReCS
Infarction ADReCS
Infection Upper Respiratory MetaADEDB
Infrequent Bowel Movements MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Insomnia ADReCS
Insulin Resistance MetaADEDB
Interleukin-2 Receptor Increased MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intestinal Diseases MetaADEDB
Intestinal Polyp MetaADEDB
Intracranial Hypertension MetaADEDB
Intubation MetaADEDB
Ischaemia ADReCS
Ischemia MetaADEDB
Itch MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Joint Instability MetaADEDB
Joint Stiffness MetaADEDB
Keloid Scar MetaADEDB
Knee Arthroplasty MetaADEDB
Laryngocele MetaADEDB
Leucopenia MetaADEDB
Leukemia MetaADEDB
Leukocytoclastic Vasculitis ADReCS
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Leukoplakia MetaADEDB
Limb Discomfort MetaADEDB
Lipase MetaADEDB
Liver Transplant MetaADEDB
Local Swelling MetaADEDB
Loss Of Consciousness ADReCS
Lumbar Puncture Abnormal MetaADEDB
Lung Disorder ADReCS
Lung Edema MetaADEDB
Lung Neoplasm MetaADEDB
Lung Transplant MetaADEDB
Lyell MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Macroglossia MetaADEDB
Malaise ADReCS
Malnourished MetaADEDB
Mammoplasty MetaADEDB
Meningioma MetaADEDB
Menopausal Symptoms ADReCS
Metabolic Encephalopathy MetaADEDB
Metastases To Peritoneum MetaADEDB
Micturition Disorder ADReCS
Migraine ADReCS
Mouth Pain MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Cramp MetaADEDB
Muscle Fatigue MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Muscle Tightness MetaADEDB
Muscle Twitching ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Mycobacterium Tuberculosis Infection MetaADEDB
Mycoplasma Infection MetaADEDB
Myocardial Infarction ADReCS
Myocardial Reperfusion Injury MetaADEDB
Myoclonic Epilepsy MetaADEDB
Myoclonus MetaADEDB
Nasal Congestion MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Nephritis Interstitial MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nervousness ADReCS
Neuromuscular Diseases MetaADEDB
Neuromuscular Manifestations MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Night Blindness MetaADEDB
Nocturia ADReCS
Nodule On Extremity MetaADEDB
Nodule Skin MetaADEDB
Nosocomial Infection MetaADEDB
Obstructive Airways Disorder ADReCS
Ocular Icterus MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Off Label Use MetaADEDB
Oliguria MetaADEDB
Optic Neuropathy MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Osteoporosis MetaADEDB
Osteosclerosis MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palpitations ADReCS
Pancreatitis ADReCS
Panel-Reactive Antibody Increased MetaADEDB
Paraesthesia ADReCS
Parkinson Disease Secondary MetaADEDB
Parkinsonian Disorders MetaADEDB
Parosmia ADReCS
Peau DOrange MetaADEDB
Peripheral Ischaemia ADReCS
Peripheral Nervous System Diseases MetaADEDB
Peripheral Vascular Disorder ADReCS
Petechia MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phlebothrombosis MetaADEDB
Photosensitivity Disorders MetaADEDB
Pigmentary Retinopathy MetaADEDB
Plaque Atherosclerotic MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleurodynia Epidemic MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumothorax MetaADEDB
Pollakiuria ADReCS
Polyneuropathy Toxic MetaADEDB
Polyuria ADReCS
Porphyria Acute Intermittent MetaADEDB
Post Procedural Bile Leak MetaADEDB
Pre-Eclampsia MetaADEDB
Precocious Puberty MetaADEDB
Proteinuria MetaADEDB
Pruritus ADReCS
Psychomotor Hyperactivity ADReCS
Pulmonary Arrest MetaADEDB
Pulmonary Venous Thrombosis MetaADEDB
Pulse Abnormal ADReCS
Purpura ADReCS
Pyothorax MetaADEDB
Quality Of Life Decreased MetaADEDB
Radical Mastectomy MetaADEDB
Rash ADReCS
Rash Erythematous ADReCS
Rash Maculo-Papular ADReCS
Reflux Laryngitis MetaADEDB
Renal Function Test Abnormal MetaADEDB
Respiratory Failure MetaADEDB
Retinal Anomaly Congenital MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinitis ADReCS
Rigors SIDER
Rotavirus Infection MetaADEDB
Serum Sickness-Like Reaction ADReCS
Sexual Dysfunction ADReCS
Shock ADReCS
Sinus Disorder MetaADEDB
Skin Cold Clammy ADReCS
Skin Discolouration ADReCS
Skin Hypertrophy MetaADEDB
Skin Induration MetaADEDB
Skin Lesion MetaADEDB
Skin Odour Abnormal MetaADEDB
Skin Plaque MetaADEDB
Skin Tightness MetaADEDB
Sleep Disorder MetaADEDB
Snake Bite MetaADEDB
Somnolence ADReCS
Speech Disorder MetaADEDB
Speech Rehabilitation MetaADEDB
Spondylitis MetaADEDB
Sputum Culture Positive MetaADEDB
Sputum Discoloured MetaADEDB
Status Epilepticus MetaADEDB
Stenotrophomonas Infection MetaADEDB
Stevens-Johnson Syndrome ADReCS
Sticky Skin ADReCS
Subarachnoid Haemorrhage MetaADEDB
Subcutaneous Nodule MetaADEDB
Sudden Death MetaADEDB
Sweating SIDER
Sweating Increased SIDER
Syncope ADReCS
Tachycardia ADReCS
Telangiectasis MetaADEDB
Tension ADReCS
Thirst ADReCS
Thrombocytopenia ADReCS
Thrombocytopenic Purpura ADReCS
Thyroxine Abnormal MetaADEDB
Tinnitus ADReCS
Tongue Discolouration ADReCS
Tooth Discolouration ADReCS
Toxic Epidermal Necrolysis ADReCS
Transaminases Increased ADReCS
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Ulcer MetaADEDB
Urinary Incontinence Stress MetaADEDB
Urine Abnormality MetaADEDB
Urine Colour Abnormal MetaADEDB
Urine Osmolarity Decreased MetaADEDB
Urine Output Increased ADReCS
Urine Uric Acid Decreased MetaADEDB
Urticaria ADReCS
Vascular Dementia MetaADEDB
Vascular Purpura ADReCS
Vasculitis ADReCS
Ventricular Fibrillation MetaADEDB
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Visual Accommodation Disturbance Of ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Decreased ADReCS
Weight Increased ADReCS
Wheeze MetaADEDB
Wound Infection Pseudomonas MetaADEDB
Wrist Surgery MetaADEDB
Xerophthalmia ADReCS

InAADR: Drug-Protein-ADRs database