InAADR

Drug Information

Drug Name: Amifostine (20537-88-6)
PubChem ID: 2141
SMILES: C(CN)CNCCSP(=O)(O)O
InchiKey: JKOQGQFVAUAYPM-UHFFFAOYSA-N
Therapeutic Category: Protective Agents, Radiation-Protective Agents

Computed Drug Properties

Molecular Weight (dalton): 214.227
LogP: -0.2493
Ring Count: 0
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 95.58

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Hernia MetaADEDB
Abnormal Laboratory Findings MetaADEDB
Abnormal Lfts MetaADEDB
Abscess Bacterial MetaADEDB
Accident At Work MetaADEDB
Aching Joints MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Injury MetaADEDB
Acute Lung Injury MetaADEDB
Adhesion MetaADEDB
Administration Site Pain MetaADEDB
Adnexa Uteri Cyst MetaADEDB
Afib MetaADEDB
Agranulocytoses MetaADEDB
Alcohol Withdrawal Syndrome MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Reaction ADReCS
Allergies MetaADEDB
Alopecia MetaADEDB
Alpha Haemolytic Streptococcal Infection MetaADEDB
Anaesthesia MetaADEDB
Anaphylactic Reaction MetaADEDB
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anemia Refractory With Excess Of Blasts MetaADEDB
Anemia Sideroblastic MetaADEDB
Angiopathy MetaADEDB
Anorexia MetaADEDB
Antimicrobial Susceptibility Test Resistant MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Apathy MetaADEDB
Apnoea ADReCS
Aptyalism MetaADEDB
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arthroscopy MetaADEDB
Asthenia MetaADEDB
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrial Flutter ADReCS
Back Pain MetaADEDB
Bacterial Endocarditis MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Toxaemia MetaADEDB
Basal Cell Carcinoma MetaADEDB
Belching MetaADEDB
Bladder Cancer MetaADEDB
Bladder Cancer Stage Iv MetaADEDB
Bladder Inflammation MetaADEDB
Bleb MetaADEDB
Bleeding Gums MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Culture Positive MetaADEDB
Blood In Urine MetaADEDB
Blood Potassium MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Immeasurable MetaADEDB
Blood Sodium MetaADEDB
Blood Test Abnormal MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased ADReCS
Bone Density Decreased MetaADEDB
Bone Disorder MetaADEDB
Bone Marrow Diseases MetaADEDB
Bone Spur MetaADEDB
Bradycardia ADReCS
Brain Oedema MetaADEDB
Breast Neoplasms MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchitis MetaADEDB
Bulging MetaADEDB
Bundle Branch Block Left MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation Mucosal MetaADEDB
Burns First Degree MetaADEDB
Burns Second Degree MetaADEDB
Bursitis MetaADEDB
Calcific Deposits Removal MetaADEDB
Candida Infection MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carcinoma Non-Small-Cell Lung MetaADEDB
Cardiac Arrest ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Enzymes Increased MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Flutter ADReCS
Cardiogenic Shock MetaADEDB
Cardiomyopathies MetaADEDB
Carpal Tunnel MetaADEDB
Cataract MetaADEDB
Catheter Placement MetaADEDB
Catheter Related Infection MetaADEDB
Catheter Sepsis MetaADEDB
Catheter Site Infection MetaADEDB
Catheter Site Pain MetaADEDB
Central Line Infection MetaADEDB
Central Venous Catheter Removal MetaADEDB
Cerebral Artery Occlusion MetaADEDB
Cervical Dysplasia MetaADEDB
Cervical Spinal Stenosis MetaADEDB
Cervicalgia MetaADEDB
Cheilitis MetaADEDB
Chest Discomfort ADReCS
Chest Pain ADReCS
Chest Tightness ADReCS
Chill MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholecystitis Infective MetaADEDB
Chronic Obstructive Airways Disease Exacerbated MetaADEDB
Chronic Sinusitis MetaADEDB
Coldness SIDER
Colitis MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Convulsion ADReCS
Corneal Disorder MetaADEDB
Corneal Oedema MetaADEDB
Corneal Perforation MetaADEDB
Corneal Ulcer MetaADEDB
Culture Stool Positive MetaADEDB
Cutaneous Ulcer MetaADEDB
Cystitis MetaADEDB
Debridement MetaADEDB
Deep Vein Thromboses MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous MetaADEDB
Dermatitis Exfoliative ADReCS
Dermatitis Medicamentosa MetaADEDB
Dermatosis MetaADEDB
Dermographism MetaADEDB
Diarrhea MetaADEDB
Discomfort ADReCS
Disease Recurrence MetaADEDB
Disorder Of Globe MetaADEDB
Disturbance In Attention MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Drug Hypersensitivity MetaADEDB
Drug Toxicity MetaADEDB
Dry Skin MetaADEDB
Dyspnea MetaADEDB
Dyspnoea ADReCS
Ear Ache MetaADEDB
Ear Infection MetaADEDB
Edema Extremities MetaADEDB
Endodontic Procedure MetaADEDB
Endotracheal Intubation MetaADEDB
Enterobacter Infection MetaADEDB
Epicondylitis MetaADEDB
Epidermal Necrosis MetaADEDB
Erosive Oesophagitis MetaADEDB
Eruption SIDER
Erythema ADReCS
Erythema Multiforme ADReCS
Escherichia Infection MetaADEDB
Esophageal Neoplasms MetaADEDB
Esophageal Rupture MetaADEDB
Esophagitis MetaADEDB
Exanthema MetaADEDB
Extrasystoles ADReCS
Extravasation Of Diagnostic And Therapeutic Materials MetaADEDB
Extremity Pain MetaADEDB
Eye Infection MetaADEDB
Eye Swelling MetaADEDB
Facial Flushing MetaADEDB
Feeding Tube Complication MetaADEDB
Feeling Abnormal ADReCS
Feeling Cold ADReCS
Feeling Hot ADReCS
Fever MetaADEDB
Fistula MetaADEDB
Fluid Intake Reduced MetaADEDB
Flushing ADReCS
Foaming At Mouth MetaADEDB
Gallbladder Polyp MetaADEDB
Gastric Ph Decreased MetaADEDB
Gastrointestinal Diseases MetaADEDB
Genital Pruritus Female MetaADEDB
Glucose Urine MetaADEDB
Haematochezia MetaADEDB
Haemodynamic Instability MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Head And Neck Neoplasms MetaADEDB
Head Injury MetaADEDB
Hearing Loss MetaADEDB
Heart Attack MetaADEDB
Heart Diseases MetaADEDB
Heart Rate Increased MetaADEDB
Heart Valve Incompetence MetaADEDB
Hemorrhage MetaADEDB
Hepatic Veno-Occlusive Disease MetaADEDB
Hepatocellular Damage MetaADEDB
Hernia Repair MetaADEDB
Hiccough MetaADEDB
Hiccups ADReCS
Histiocytosis Haematophagic MetaADEDB
Hydronephrosis MetaADEDB
Hydroureter MetaADEDB
Hyperpigmentation MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypoaesthesia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypocalcaemia ADReCS
Hypocalcemia MetaADEDB
Hypokalaemia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypoxia ADReCS
Ill-Defined Disorder ADReCS
Impaired Healing MetaADEDB
Incoherent MetaADEDB
Infarction ADReCS
Infusion Site Mobility Decreased MetaADEDB
Injection Site Burning MetaADEDB
Injection Site Dermatitis MetaADEDB
Injection Site Discolouration MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Irritation MetaADEDB
Injection Site Papule MetaADEDB
Injection Site Pruritus MetaADEDB
Injection Site Urticaria MetaADEDB
Injection Site Vesicles MetaADEDB
Injection Site Warmth MetaADEDB
Intention Tremor MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Ischaemia ADReCS
Ischaemic Ulcer MetaADEDB
Itch MetaADEDB
Jaw Operation MetaADEDB
Joint Injury MetaADEDB
Kidney Diseases MetaADEDB
Laboratory Test Interference MetaADEDB
Laryngeal Dyspnoea MetaADEDB
Laryngeal Oedema ADReCS
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukemia Myelomonocytic Chronic MetaADEDB
Leukopenia Neonatal MetaADEDB
Lichenoid Keratosis MetaADEDB
Life Expectancy Shortened MetaADEDB
Ligament Rupture MetaADEDB
Lip Ulceration MetaADEDB
Local Reaction MetaADEDB
Local Swelling MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lyell MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphoma Mantle-Cell MetaADEDB
Lymphoma Non-Hodgkin MetaADEDB
Malaise ADReCS
Mallory-Weiss Syndrome MetaADEDB
Malnourished MetaADEDB
Mass Excision MetaADEDB
Mastication Disorder MetaADEDB
Melanocytic Naevus MetaADEDB
Meningitides MetaADEDB
Meniscus Removal MetaADEDB
Metabolic Disorder MetaADEDB
Metastases To Lung MetaADEDB
Metastases To Spine MetaADEDB
Middle Ear Inflammation MetaADEDB
Migraine MetaADEDB
Monarthritis MetaADEDB
Mouth Pain MetaADEDB
Mucosal Erosion MetaADEDB
Mucosal Haemorrhage MetaADEDB
Mucosal Inflammation MetaADEDB
Mucositis MetaADEDB
Multi-Organ Failure MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Nail Tinea MetaADEDB
Nasal Dryness MetaADEDB
Nasal Sinus Congestion MetaADEDB
Nausea ADReCS
Necrolysis Epidermal SIDER
Necrosis MetaADEDB
Neoplasia MetaADEDB
Nephrolithiasis MetaADEDB
Neuropathy Peripheral MetaADEDB
Neurotoxicity Syndromes MetaADEDB
Neutropenia MetaADEDB
Nikolsky Sign MetaADEDB
Nocturia MetaADEDB
Nystagmus MetaADEDB
Odynophagia MetaADEDB
Oedema ADReCS
Oedema Mucosal MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oliguria MetaADEDB
Onychalgia MetaADEDB
Oophorectomy Bilateral MetaADEDB
Oral Disorder MetaADEDB
Oral Fungal Infection MetaADEDB
Oral Intake Reduced MetaADEDB
Oral Mucosa Erosion MetaADEDB
Oral Mucosal Exfoliation MetaADEDB
Osteoarthritis MetaADEDB
Osteolysis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Osteosarcoma Metastatic MetaADEDB
Osteosclerosis MetaADEDB
Ototoxicity MetaADEDB
Ovarian Cancer MetaADEDB
Pain ADReCS
Pain Of Skin MetaADEDB
Palmar Erythema MetaADEDB
Pancreatic Neoplasms MetaADEDB
Paraesthesia Oral MetaADEDB
Paresthesia MetaADEDB
Pathogen Resistance MetaADEDB
Pedal Pulse Absent MetaADEDB
Pelvi-Ureteric Obstruction MetaADEDB
Periodontal Disease MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Petechia MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngeal Inflammation MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Physical Disability MetaADEDB
Platelet Count MetaADEDB
Pneumocystis Carinii Pneumonia MetaADEDB
Primary Sequestrum MetaADEDB
Procedural Complication MetaADEDB
Prostatic Mass MetaADEDB
Pruritus ADReCS
Pseudomonas Infection MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Radiation Injury MetaADEDB
Pulse Pressure Increased MetaADEDB
Purulent Discharge MetaADEDB
Pyrexia ADReCS
Radiation Associated Pain MetaADEDB
Radiation Injuries MetaADEDB
Radiation Mucositis MetaADEDB
Radiation Oesophagitis MetaADEDB
Radiation Skin Injury MetaADEDB
Radicular Pain MetaADEDB
Radicular Syndrome MetaADEDB
Rash ADReCS
Rash Generalised MetaADEDB
Recall Phenomenon MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Renal Failure ADReCS
Renal Insufficiency MetaADEDB
Respiratory Alkalosis MetaADEDB
Rhinitis MetaADEDB
Rib Fracture MetaADEDB
Rigors SIDER
Saliva Altered MetaADEDB
Salpingo-Oophorectomy MetaADEDB
Scar MetaADEDB
Scratch MetaADEDB
Seizures SIDER
Sensation Of Warmth SIDER
Serratia Infection MetaADEDB
Shock ADReCS
Skin Chapped MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration MetaADEDB
Skin Injury MetaADEDB
Skin Lesion MetaADEDB
Skin Lesion Excision MetaADEDB
Skin Neoplasm Excision MetaADEDB
Sleep Disorder MetaADEDB
Sneezing ADReCS
Soft Tissue Disorder MetaADEDB
Somnolence ADReCS
Spinal Osteoarthritis MetaADEDB
Spondylolisthesis MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Abscess MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Stem Cell Transplant MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stomach Diseases MetaADEDB
Stomatocytes Present MetaADEDB
Stress Fracture MetaADEDB
Supraventricular Tachycardia ADReCS
Surgery MetaADEDB
Symblepharon MetaADEDB
Syncope ADReCS
Synovial Cyst MetaADEDB
Synovitis MetaADEDB
Systemic Inflammatory Response Syndrome MetaADEDB
Tachycardia ADReCS
Tendinitis MetaADEDB
Tendon Injury MetaADEDB
Tendon Sheath Incision MetaADEDB
Tenosynovitis MetaADEDB
Testes Pain MetaADEDB
Testicular Mass MetaADEDB
Therapy Non-Responder MetaADEDB
Throat Tightness MetaADEDB
Thrombocytopenia MetaADEDB
Thyroid Cyst MetaADEDB
Tinea Pedis MetaADEDB
Tooth Loss MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Toxic Skin Eruption MetaADEDB
Treatment Noncompliance MetaADEDB
Tympanic Membrane Perforation MetaADEDB
Ulcer MetaADEDB
Urticaria ADReCS
Uterine Prolapse MetaADEDB
Vertebroplasty MetaADEDB
Vomiting ADReCS
White Blood Cell Disorder MetaADEDB
Wound Secretion MetaADEDB
Wound Treatment MetaADEDB
Xerostomia MetaADEDB

InAADR: Drug-Protein-ADRs database