InAADR

Drug Information

Drug Name: Adapalene (106685-40-9)
PubChem ID: 60164
SMILES: COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
InchiKey: LZCDAPDGXCYOEH-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Anti-Inflammatory Agents, Antirheumatic Agents, Dermatologic Agents, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 412.529
LogP: 6.6814
Ring Count: 3
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 46.53

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Dreams MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Abortion MetaADEDB
Aching Muscles MetaADEDB
Acne ADReCS
Acquired Night Blindness MetaADEDB
Activated Partial Thromboplastin Time Shortened MetaADEDB
Acute Hepatic Failure MetaADEDB
Afib MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Rhinitis MetaADEDB
Alopecia MetaADEDB
Anal Fissure MetaADEDB
Analgesic Drug Level Increased MetaADEDB
Anaphylactic Reaction MetaADEDB
Anger MetaADEDB
Angioedema ADReCS
Ankle Fracture MetaADEDB
Ankylosing Spondylitis MetaADEDB
Antinuclear Antibody MetaADEDB
Anxiety MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aphthous Stomatitis MetaADEDB
Appendicitis MetaADEDB
Application Site Pain ADReCS
Aptyalism MetaADEDB
Areflexia MetaADEDB
Arrhythmia MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Ascites MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asthma MetaADEDB
Atopy ADReCS
Atrial Septal Defect MetaADEDB
Atrial Tachycardia MetaADEDB
Attempted Suicide MetaADEDB
Back Ache MetaADEDB
Belligerence MetaADEDB
Biliary Dyskinesia MetaADEDB
Birth Defect MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Oestrogen Decreased MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Testosterone Decreased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Body Temperature Increased MetaADEDB
Brain Concussion MetaADEDB
Brain Damage MetaADEDB
Brain Oedema MetaADEDB
Breast Cyst MetaADEDB
Bronchitis MetaADEDB
Bruise MetaADEDB
Bulbar Palsy MetaADEDB
Burning Sensation ADReCS
Cartilage Development Disorder MetaADEDB
Cerebral Venous Thrombosis MetaADEDB
Cervical Discharge MetaADEDB
Cervicalgia MetaADEDB
Choking Sensation MetaADEDB
Cholangitis Sclerosing MetaADEDB
Chromaturia MetaADEDB
Chromosomal Deletion MetaADEDB
Chronic Kidney Disease MetaADEDB
Clostridial Infection MetaADEDB
Cognitive Disorder MetaADEDB
Colon Neoplasm MetaADEDB
Colpitis MetaADEDB
Complications Of Transplant Surgery MetaADEDB
Condition Aggravated MetaADEDB
Congenital Hand Malformation MetaADEDB
Congenital Heart Disease MetaADEDB
Congenital Heart Valve Disorder MetaADEDB
Congenital Ventricular Septal Defect MetaADEDB
Conjunctivitis ADReCS
Contact Dermatitis MetaADEDB
Convulsion ADReCS
Coronary Artery Insufficiency MetaADEDB
Cough MetaADEDB
Csf Pressure Increased MetaADEDB
Csf Protein MetaADEDB
Csf Protein Increased MetaADEDB
Culture Positive MetaADEDB
Dandy-Walker Syndrome MetaADEDB
Decreased Libido MetaADEDB
Demyelination MetaADEDB
Dental Caries MetaADEDB
Depressed Mood MetaADEDB
Dermatitis ADReCS
Dermatitis Atopic ADReCS
Dermatitis Contact ADReCS
Dermatitis Irritant Contact SIDER
Dermatitis Seborrheic MetaADEDB
Dextrocardia MetaADEDB
Diagnostic Procedure MetaADEDB
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disinhibition MetaADEDB
Disturbance In Attention MetaADEDB
Disturbance In Sexual Arousal MetaADEDB
Disturbance In Social Behaviour MetaADEDB
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Ineffective MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Skin ADReCS
Ear Infection MetaADEDB
Eating Disorder MetaADEDB
Ectopic Kidney MetaADEDB
Eczema ADReCS
Embolism MetaADEDB
Enterocolitis MetaADEDB
Epiphyses Premature Fusion MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Euphoric Mood MetaADEDB
Exercise Lack Of MetaADEDB
Eye Pain ADReCS
Eye Pruritus MetaADEDB
Eye Swelling MetaADEDB
Eyelid Oedema ADReCS
Face Oedema ADReCS
Face Pain MetaADEDB
Facial Neuralgia MetaADEDB
Faeces Pale MetaADEDB
Fatigue MetaADEDB
Feeding Disorder Neonatal MetaADEDB
Feeling Abnormal MetaADEDB
Flashing Lights MetaADEDB
Flat Affect MetaADEDB
Flooding MetaADEDB
Foetal Disorder SIDER
Foetal Growth Retardation MetaADEDB
Gall Bladder MetaADEDB
Gastrointestinal Inflammation MetaADEDB
Globulinuria MetaADEDB
Goiter MetaADEDB
Haematochezia MetaADEDB
Heart Attack MetaADEDB
Heart Rate Increased MetaADEDB
Heart Valve Incompetence MetaADEDB
Hepatitis ADReCS
Hernia Inguinal MetaADEDB
Herpes Nos SIDER
Herpes Simplex ADReCS
Herpes Virus Infection ADReCS
High Blood Pressure MetaADEDB
Hoarseness MetaADEDB
Hostility MetaADEDB
Hypercoagulation MetaADEDB
Hypersensitivity MetaADEDB
Hypertonia MetaADEDB
Hypoaesthesia Oral MetaADEDB
Hypocoagulable State MetaADEDB
Hypospadias MetaADEDB
Hypothyroid MetaADEDB
Impulse-Control Disorder MetaADEDB
Infection Upper Respiratory MetaADEDB
Inflammatory Bowel Disease MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
International Normalised Ratio Increased MetaADEDB
Interstitial Lung Disease ADReCS
Intertrigo MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intracranial Venous Sinus Thrombosis MetaADEDB
Irritation Skin MetaADEDB
Itch MetaADEDB
Joint Stiffness MetaADEDB
Judgement Impaired MetaADEDB
Jugular Vein Thrombosis MetaADEDB
Keratitis ADReCS
Keratitis Sicca MetaADEDB
Keratoconjunctivitis SIDER
Kidney Malformation MetaADEDB
Lactose Intolerance MetaADEDB
Lethargy MetaADEDB
Light Sensitivity MetaADEDB
Limb Injury MetaADEDB
Lip Dry MetaADEDB
Lip Swelling ADReCS
Lipids Increased MetaADEDB
Liver Transplant Rejection MetaADEDB
Lumbar Puncture Abnormal MetaADEDB
Lung Neoplasm MetaADEDB
Lymphoid Interstitial Pneumonia SIDER
Maternal Drugs Affecting Foetus MetaADEDB
Multiple Congenital Abnormalities MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Nasopharyngitis MetaADEDB
Nausea MetaADEDB
Neonatal Tachycardia MetaADEDB
Neoplasm Of Appendix MetaADEDB
Nephropathy Toxic MetaADEDB
Nervous Tension MetaADEDB
Neuralgia MetaADEDB
Neurodermatitis MetaADEDB
Neutropenic Sepsis MetaADEDB
Occult Blood Positive MetaADEDB
Ocular Icterus MetaADEDB
Oedema ADReCS
Oestradiol Decreased MetaADEDB
Optic Neuritis ADReCS
Oropharyngeal Pain MetaADEDB
Osteomyelitis MetaADEDB
Pain ADReCS
Pain In Throat MetaADEDB
Papilloedema ADReCS
Periodontitis MetaADEDB
Persistent Left Superior Vena Cava MetaADEDB
Personality Change MetaADEDB
Personality Disorder MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Photosensitive Rash MetaADEDB
Post Procedural Haematoma MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Pregnancy On Oral Contraceptive MetaADEDB
Protein Total Decreased MetaADEDB
Pruritus ADReCS
Pulmonary Hypoplasia MetaADEDB
Pulmonary Malformation MetaADEDB
Pulmonary Sequestration MetaADEDB
Pulpitis Dental MetaADEDB
Rash ADReCS
Rash Vesicular ADReCS
Red Blood Cells Csf Positive MetaADEDB
Respiratory Tract Congestion MetaADEDB
Rhabdomyolysis MetaADEDB
Risus Sardonicus MetaADEDB
Sacroiliitis MetaADEDB
Scar MetaADEDB
Scimitar Syndrome MetaADEDB
Scleroderma MetaADEDB
Screaming MetaADEDB
Seborrhoeic Dermatitis ADReCS
Secretion Discharge MetaADEDB
Self Esteem Decreased MetaADEDB
Semen Volume Decreased MetaADEDB
Sensation Of Heaviness MetaADEDB
Sensory Disturbance MetaADEDB
Sinus Headache MetaADEDB
Sinusitis MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration ADReCS
Skin Discomfort ADReCS
Skin Exfoliation ADReCS
Skin Irritation ADReCS
Skin Oedema ADReCS
Sleep Disorder MetaADEDB
Small Intestinal Obstruction MetaADEDB
Snoring MetaADEDB
Spinning Sensation MetaADEDB
Sputum Discoloured MetaADEDB
Staphylococcal Infection MetaADEDB
Stinging SIDER
Subdural Haemorrhage MetaADEDB
Sunburn ADReCS
Swelling ADReCS
Synovitis MetaADEDB
Thyroid Cancer MetaADEDB
Tooth Disease MetaADEDB
Transposition Of The Great Vessels MetaADEDB
Transverse Sinus Thrombosis MetaADEDB
Unevaluable Event MetaADEDB
Urinary Tract Disorder MetaADEDB
Urticaria ADReCS
Weight Gain MetaADEDB
Wisdom Teeth Removal MetaADEDB
Withdrawal Syndrome MetaADEDB
Xerosis MetaADEDB

InAADR: Drug-Protein-ADRs database