InAADR

Drug Information

Drug Name: Vinblastine (865-21-4)
PubChem ID: 3823887
SMILES: CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
InchiKey: JXLYSJRDGCGARV-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 810.989
LogP: 3.9909
Ring Count: 3
Hydrogen Bond Acceptor Count: 12
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 154.1

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Injury MetaADEDB
Abdominal Pain ADReCS
Abnormal Laboratory Findings MetaADEDB
Abortion MetaADEDB
Abscess Bacterial MetaADEDB
Accident MetaADEDB
Accident At Work MetaADEDB
Aching Joints MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Acute Leukaemia MetaADEDB
Adenocarcinoma Of Lung MetaADEDB
Adenoiditis MetaADEDB
Adenopathy MetaADEDB
Adnexa Uteri Mass MetaADEDB
Adynamic Ileus MetaADEDB
Agranulocytosis MetaADEDB
Allergic Dermatitis MetaADEDB
Allergies MetaADEDB
Alopecia ADReCS
Amniotic Fluid Volume Decreased MetaADEDB
Anaemia ADReCS
Androgen Deficiency MetaADEDB
Angina Pectoris ADReCS
Anhidrosis MetaADEDB
Anorexia ADReCS
Anosmia MetaADEDB
Anti-Gad Antibody MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Apoptosis MetaADEDB
Appendectomy MetaADEDB
Appendicitis Perforated MetaADEDB
Arterial Insufficiency MetaADEDB
Arthralgia MetaADEDB
Asthenia ADReCS
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrophy MetaADEDB
Autonomic Nervous System Diseases MetaADEDB
Azoospermia MetaADEDB
B-Cell Lymphoma MetaADEDB
Back Ache MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Sepsis MetaADEDB
Band Neutrophil Count Increased MetaADEDB
Biliary Cirrhosis Primary MetaADEDB
Biopsy Bone Marrow MetaADEDB
Bleeding Vaginal MetaADEDB
Blindness Cortical MetaADEDB
Blood Calcium MetaADEDB
Blood Parathyroid Hormone Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure Syndromes MetaADEDB
Bone Marrow Toxicity MetaADEDB
Bone Pain ADReCS
Bone Spur MetaADEDB
Bradycardia MetaADEDB
Breast Neoplasms MetaADEDB
Bronchiolitis MetaADEDB
Bronchoalveolar Lavage Abnormal MetaADEDB
Budd-Chiari Syndrome MetaADEDB
Burning Sensation MetaADEDB
Caesarean Section MetaADEDB
Cancer Pain MetaADEDB
Carcinoma MetaADEDB
Carcinoma Embryonal MetaADEDB
Carcinoma Non-Small-Cell Lung MetaADEDB
Carcinoma Renal Cell MetaADEDB
Carcinoma Transitional Cell MetaADEDB
Cardiac Murmur MetaADEDB
Castleman Disease MetaADEDB
Catheter Related Complication MetaADEDB
Catheter Site Erythema MetaADEDB
Cellulitis MetaADEDB
Central Nervous System Lesion MetaADEDB
Cerebrovascular Accident ADReCS
Cervicalgia MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Infection MetaADEDB
Chest Pain MetaADEDB
Chills MetaADEDB
Choking Sensation MetaADEDB
Chondrosarcoma MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Clotting MetaADEDB
Colorectal Neoplasms MetaADEDB
Constipation ADReCS
Contact Dermatitis MetaADEDB
Convulsion ADReCS
Coronary Artery Disease MetaADEDB
Creatinine Renal Clearance Decreased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cytolytic Hepatitis MetaADEDB
Deglutition Disorder MetaADEDB
Demyelination MetaADEDB
Depilation ADReCS
Depression ADReCS
Dermatitides MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diffuse Large B-Cell Lymphoma MetaADEDB
Disease Complication MetaADEDB
Disease Recurrence MetaADEDB
Disorder Lung MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Dysgerminoma MetaADEDB
Dysmenorrhea MetaADEDB
Dysphonia MetaADEDB
Dystrophic Calcification MetaADEDB
Dysuria MetaADEDB
Ear Ache MetaADEDB
Ebv Infection MetaADEDB
Eczema MetaADEDB
Electrocardiogram Abnormal ADReCS
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Endometrial Cancer MetaADEDB
Enlarged Spleen MetaADEDB
Enterobacter Bacteraemia MetaADEDB
Enterocolitis Haemorrhagic ADReCS
Erectile Dysfunction MetaADEDB
Erosive Oesophagitis MetaADEDB
Erythema Infectiosum MetaADEDB
Erythema Migrans MetaADEDB
Eye Swelling MetaADEDB
Facial Pain MetaADEDB
Fallopian Tube Disorder MetaADEDB
Fallopian Tube Operation MetaADEDB
Fanconi Syndrome MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Feeding Disorder MetaADEDB
Feeling Abnormal MetaADEDB
Femoral Neck Fracture MetaADEDB
Fever MetaADEDB
Fibrinolysis MetaADEDB
Fibrous Histiocytoma MetaADEDB
Foetal Growth Retardation MetaADEDB
Foot Fracture MetaADEDB
Fungal Disease MetaADEDB
Gangrene MetaADEDB
Gastric Hyperplasia MetaADEDB
Groin Abscess MetaADEDB
Gynaecomastia MetaADEDB
Haemangioma Of Skin MetaADEDB
Haematotoxicity MetaADEDB
Haemodialysis MetaADEDB
Haemophilus Infection MetaADEDB
Head And Neck Neoplasms MetaADEDB
Headache ADReCS
Hearing Loss Conductive MetaADEDB
Heart Failure MetaADEDB
Hematoma Subdural MetaADEDB
Hemolytic-Uremic Syndrome MetaADEDB
Hepatic Lesion MetaADEDB
Hepatic Neoplasia MetaADEDB
Hepatic Veno-Occlusive Disease MetaADEDB
Hepatitis MetaADEDB
Hepatitis B Virus MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Histiocytosis Langerhans-Cell MetaADEDB
Histoplasmosis MetaADEDB
Hodgkin Disease MetaADEDB
Hodgkin Disease Nodular Sclerosis Stage Unspecified MetaADEDB
Hodgkin Disease Stage I MetaADEDB
Hyperbilirubinemia MetaADEDB
Hyperlipaemia MetaADEDB
Hypertension ADReCS
Hypertension Renovascular MetaADEDB
Hypertonia MetaADEDB
Hypesthesia MetaADEDB
Hypoaesthesia ADReCS
Hypokalemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hyponatremia MetaADEDB
Hyporeflexia ADReCS
Hyposmia MetaADEDB
Hypotension MetaADEDB
Hypoxia MetaADEDB
Idiosyncratic Drug Reaction MetaADEDB
Ileus ADReCS
Immunosuppression MetaADEDB
Impaired Healing MetaADEDB
Impetigo MetaADEDB
Inappropriate Adh Syndrome MetaADEDB
Incision Site Infection MetaADEDB
Infective Spondylitis MetaADEDB
Intercostal Retraction MetaADEDB
International Normalised Ratio Decreased MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Ischemia MetaADEDB
Joint Sprain MetaADEDB
Keratitis Sicca MetaADEDB
Kidney Diseases MetaADEDB
Klebsiella Bacteraemia MetaADEDB
Klebsiella Sepsis MetaADEDB
Kyphosis MetaADEDB
Lacrimation Increased MetaADEDB
Langerhans Cell Granulomatosis MetaADEDB
Leucopenia MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Lichenoid Keratosis MetaADEDB
Limb Injury MetaADEDB
Liver Neoplasms MetaADEDB
Loss Of Weight MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Lymphadenectomy MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Lymphoproliferative Disorder MetaADEDB
Malaise ADReCS
Malaria MetaADEDB
Malignant Neoplasm Of Spinal Cord MetaADEDB
Malignant Soft Tissue Neoplasm MetaADEDB
Mediastinal Tumor MetaADEDB
Melanoma MetaADEDB
Melanosis MetaADEDB
Metastases To Bone Marrow MetaADEDB
Metastatic Neoplasm MetaADEDB
Middle Ear Inflammation MetaADEDB
Migraine Disorders MetaADEDB
Mononeuritis MetaADEDB
Mouth Breathing MetaADEDB
Mucormycosis MetaADEDB
Mucosal Inflammation MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Muscle Cramp MetaADEDB
Muscle Inflammation MetaADEDB
Muscle Tightness MetaADEDB
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Myelitis Transverse MetaADEDB
Myelocytosis MetaADEDB
Myeloid Maturation Arrest MetaADEDB
Myocardial Infarction ADReCS
Myocardial Ischemia MetaADEDB
Nausea ADReCS
Neck Mass MetaADEDB
Neoplasm Metastasis MetaADEDB
Neoplasm Recurrence MetaADEDB
Neoplasms Experimental MetaADEDB
Neoplasms Germ Cell And Embryonal MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Neuralgia MetaADEDB
Neuritis MetaADEDB
Neuroendocrine Carcinoma MetaADEDB
Neuropathy Peripheral MetaADEDB
Neurotoxicity Syndromes MetaADEDB
Neutropenia MetaADEDB
Neutropenic Sepsis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Non-Hodgkin Lymphoma MetaADEDB
Normal Newborn MetaADEDB
Odynophagia MetaADEDB
Oligohydramnios MetaADEDB
Oliguria MetaADEDB
Oral Disorder MetaADEDB
Oral Herpes MetaADEDB
Osteolysis MetaADEDB
Ovarian Mass MetaADEDB
Ovarian Neoplasms MetaADEDB
Overdose MetaADEDB
Pain MetaADEDB
Pain In Jaw ADReCS
Pallor MetaADEDB
Palpitation MetaADEDB
Pancreatic Neoplasm MetaADEDB
Papillary Serous Endometrial Carcinoma MetaADEDB
Paraesthesia ADReCS
Paraesthesia Oral MetaADEDB
Parathyroid Tumour Benign MetaADEDB
Paresis MetaADEDB
Paresthesia MetaADEDB
Pemphigus Benign Familial MetaADEDB
Penile Pain MetaADEDB
Peptic Ulcer Haemorrhage ADReCS
Performance Status Decreased MetaADEDB
Peripheral Nervous System Diseases MetaADEDB
Peripheral Neuritis ADReCS
Peripheral Sensorimotor Neuropathy MetaADEDB
Peritoneal Neoplasm MetaADEDB
Peritonitis MetaADEDB
Pharyngitis ADReCS
Photophobia ADReCS
Plasmacytosis MetaADEDB
Pneumomediastinum MetaADEDB
Pneumonia MetaADEDB
Pneumonitis Chemical MetaADEDB
Pneumopericardium MetaADEDB
Pneumothorax MetaADEDB
Polyneuropathy MetaADEDB
Post Procedural Hypothyroidism MetaADEDB
Posterior Leukoencephalopathy Syndrome MetaADEDB
Pregnancy Induced Hypertension MetaADEDB
Premature Baby MetaADEDB
Prostatic Neoplasms MetaADEDB
Prostatomegaly MetaADEDB
Proteinuria MetaADEDB
Pseudomonas Infections MetaADEDB
Pulmonary Fibrosis MetaADEDB
Pulmonary Function Test Abnormal MetaADEDB
Pulmonary Function Test Decreased MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Interstitial Emphysema Syndrome MetaADEDB
Pulmonary Sarcoidosis MetaADEDB
Pulmonary Toxicity MetaADEDB
Purulent Discharge MetaADEDB
Radiation Oesophagitis MetaADEDB
Radiation Pneumonitis MetaADEDB
Rash Generalised MetaADEDB
Rash Vesicular ADReCS
Raynaud Disease MetaADEDB
Raynaud Phenomenon ADReCS
Rectal Haemorrhage ADReCS
Recurrent Cancer MetaADEDB
Reflex Abnormal MetaADEDB
Reflexes Abnormal MetaADEDB
Relapsing Fever MetaADEDB
Renal Artery Obstruction MetaADEDB
Renal Atrophy MetaADEDB
Renal Impairment MetaADEDB
Renal Insufficiency MetaADEDB
Reticulocytopenia MetaADEDB
Retroperitoneal Neoplasm MetaADEDB
Rhabdomyosarcoma MetaADEDB
Rhinitis Seasonal MetaADEDB
Road Traffic Accident MetaADEDB
Salivary Gland Enlargement MetaADEDB
Sarcoidosis MetaADEDB
Sarcoma Kaposi MetaADEDB
Scleroderma MetaADEDB
Scoliosis MetaADEDB
Seizures MetaADEDB
Senile Dementia MetaADEDB
Sense Of Oppression MetaADEDB
Sensory Disturbance MetaADEDB
Sensory Loss MetaADEDB
Sepsis MetaADEDB
Sepsis Pasteurella MetaADEDB
Serum Ferritin Increased MetaADEDB
Shoulder Pain MetaADEDB
Sinus Disorder MetaADEDB
Sinus Polyp MetaADEDB
Sinusitis MetaADEDB
Sinusitis Fungal MetaADEDB
Skin Depigmentation MetaADEDB
Skull Fractured Base MetaADEDB
Small For Dates Baby MetaADEDB
Somatoform Disorder MetaADEDB
Spermatogenesis Abnormal MetaADEDB
Spinal Cord Compression MetaADEDB
Spinal Disorder MetaADEDB
Spinning Sensation MetaADEDB
Streptococcal Infection MetaADEDB
Subcutaneous Emphysema MetaADEDB
Superior Vena Cava Syndrome MetaADEDB
Synovial Cyst MetaADEDB
Systemic Sclerosis Pulmonary MetaADEDB
Teratocarcinoma MetaADEDB
Testicular Neoplasms MetaADEDB
Therapeutic Response Decreased MetaADEDB
Therapy Non-Responder MetaADEDB
Throat Tightness MetaADEDB
Thrombocytopenia ADReCS
Thrombosis MetaADEDB
Thyroid Neoplasia MetaADEDB
Transmission Of An Infectious Agent Via A Medicinal Product MetaADEDB
Treatment Related Secondary Malignancy MetaADEDB
Tumour Invasion MetaADEDB
Tumour Lysis Syndrome MetaADEDB
Tumour Pain ADReCS
Umbilical Cord Abnormality MetaADEDB
Undifferentiated Sarcoma MetaADEDB
Urethral Neoplasms MetaADEDB
Urinary Bladder Neoplasms MetaADEDB
Urinary Tract Disorder MetaADEDB
Vaginal Neoplasms MetaADEDB
Vanishing Bile Duct Syndrome MetaADEDB
Vascular Diseases MetaADEDB
Vascular Encephalopathy MetaADEDB
Vasogenic Cerebral Oedema MetaADEDB
Vomiting ADReCS
Vulval Disorder MetaADEDB
Wound Infection MetaADEDB

InAADR: Drug-Protein-ADRs database