| Drug Name: | Loratadine (79794-75-5) |
|---|---|
| PubChem ID: | 3957 |
| SMILES: | CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1 |
| InchiKey: | JCCNYMKQOSZNPW-UHFFFAOYSA-N |
| Therapeutic Category: | Anti-Allergic Agents, Antipruritics, Dermatologic Agents, Histamine Agents, Histamine Antagonists, Histamine H1 Antagonists, Neurotransmitter Agents |
| Molecular Weight (dalton) | : | 382.891 |
| LogP | : | 4.8878 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 42.43 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Amiodarone (1951-25-3) | Torsade De Pointes | Antagonistic | Uncertain | Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category