InAADR

Drug Information

Drug Name: Chlorthalidone (77-36-1)
PubChem ID: 2732
SMILES: C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O
InchiKey: JIVPVXMEBJLZRO-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 338.772
LogP: 0.9242
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 109.49

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Hernia MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Sepsis MetaADEDB
Abnormal Gait MetaADEDB
Abscess Bacterial MetaADEDB
Accelerated Hypertension MetaADEDB
Accommodation Disorder MetaADEDB
Aching Joints MetaADEDB
Actinomycosis MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Adenocarcinoma MetaADEDB
Adh Inappropriate MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Agranulocytosis ADReCS
Alkalosis MetaADEDB
Allergies MetaADEDB
Amnesia MetaADEDB
Amoebic Colitis MetaADEDB
Amyloidosis MetaADEDB
Anaemia ADReCS
Angiitis Necrotising SIDER
Angina MetaADEDB
Angioedema MetaADEDB
Angle Closure Glaucoma MetaADEDB
Anorectal Disorder MetaADEDB
Anorexia ADReCS
Anoxic Encephalopathy MetaADEDB
Anticonvulsant Drug Level Increased MetaADEDB
Antipsychotic Drug Level Below Therapeutic MetaADEDB
Aortic Stenosis MetaADEDB
Aphthous Stomatitis MetaADEDB
Aplastic Anaemia ADReCS
Apnea MetaADEDB
Apparent Death MetaADEDB
Appendicitis MetaADEDB
Appetite Disorder MetaADEDB
Application Site Pain MetaADEDB
Aptyalism MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriovenous Graft Thrombosis MetaADEDB
Arthritis MetaADEDB
Arthritis Bacterial MetaADEDB
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Atelectasis MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Autonomic Instability MetaADEDB
Back Ache MetaADEDB
Bacterial Rhinitis MetaADEDB
Bad Breath MetaADEDB
Bartter Syndrome MetaADEDB
Benign Neoplasm MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy Thyroid Gland MetaADEDB
Bladder Inflammation MetaADEDB
Bleeding Gums MetaADEDB
Blood Cholesterol MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Sodium MetaADEDB
Blood Uric Acid Increased ADReCS
Blurred Vision MetaADEDB
Bone Erosion MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Operation MetaADEDB
Bone Spur MetaADEDB
Bradyarrhythmia MetaADEDB
Brain Oedema MetaADEDB
Brain Stem Infarction MetaADEDB
Breast Cancer MetaADEDB
Breath Sounds MetaADEDB
Bronchopneumonia MetaADEDB
Cachectic MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Fibrillation MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomegaly MetaADEDB
Cardiovascular Diseases MetaADEDB
Cataract MetaADEDB
Catheterisation Cardiac MetaADEDB
Cauda Equina Syndrome MetaADEDB
Central Nervous System Lesion MetaADEDB
Central Venous Catheter Removal MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cervical Laser Therapy MetaADEDB
Cervical Vertebral Fracture MetaADEDB
Cervix Disorder MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Pain MetaADEDB
Choking Sensation MetaADEDB
Cholecystectomies MetaADEDB
Chondrectomy MetaADEDB
Chondrocalcinosis MetaADEDB
Chromosome Analysis Abnormal MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Clostridium Colitis MetaADEDB
Coccydynia MetaADEDB
Cognitive Disorder MetaADEDB
Colectomy MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Coronary Artery Occlusion MetaADEDB
Coronary Artery Restenosis MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coronary Disease MetaADEDB
Cramp Muscle SIDER
Cutaneous Mycosis MetaADEDB
Cutaneous Vasculitis ADReCS
Death MetaADEDB
Debridement MetaADEDB
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Deep Vein Thromboses MetaADEDB
Dehydration MetaADEDB
Delirium Tremens MetaADEDB
Dental Fistula MetaADEDB
Dermatitis ADReCS
Dermographism MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Foot MetaADEDB
Diabetic Neuropathy MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Dilatation Atrial MetaADEDB
Dilatation Ventricular MetaADEDB
Disease Progression MetaADEDB
Dislocation MetaADEDB
Dislocation Of Vertebra MetaADEDB
Disorders Of Excessive Somnolence MetaADEDB
Diverticulitis MetaADEDB
Diverticulosis MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Interaction MetaADEDB
Drug Intolerance MetaADEDB
Drug Withdrawal Headache MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Eye MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Duodenitis MetaADEDB
Dysgeusia MetaADEDB
Easy Bruisability MetaADEDB
Ecchymoses MetaADEDB
Economic Problem MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Ejaculation Delayed MetaADEDB
Elevated Triglycerides MetaADEDB
Emotional Distress MetaADEDB
Endophthalmitis MetaADEDB
Enterocutaneous Fistula MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epistaxis MetaADEDB
Erectile Dysfunction ADReCS
Erythema MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Facet Joint Syndrome MetaADEDB
Facial Palsy MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Feeling Abnormal MetaADEDB
Fibroids MetaADEDB
Forearm Fracture MetaADEDB
Gastric Irritation SIDER
Gastroenteritis Rotavirus MetaADEDB
Gastroenteritis Viral MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Toxicity MetaADEDB
General Physical Condition MetaADEDB
Glaucoma MetaADEDB
Glycosuria ADReCS
Granulocytosis MetaADEDB
Haematoma MetaADEDB
Haemoglobin Increased MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhoids MetaADEDB
Hand Fracture MetaADEDB
Headache ADReCS
Heart Transplant MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Neoplasia MetaADEDB
Hernia Repair MetaADEDB
Herpes Zoster MetaADEDB
Hoarseness MetaADEDB
Hospitalisation MetaADEDB
Hyperaldosteronism MetaADEDB
Hyperalimentation MetaADEDB
Hypercalcemia MetaADEDB
Hypercapnia MetaADEDB
Hypercholesterolemia MetaADEDB
Hyperglycaemia ADReCS
Hyperlipaemia MetaADEDB
Hypermetropia MetaADEDB
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hypertension Malignant MetaADEDB
Hypertrichosis MetaADEDB
Hyperuricaemia ADReCS
Hypokalaemia MetaADEDB
Hypokalemia MetaADEDB
Hyponatremia MetaADEDB
Hypophagia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypovolaemia MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Immunodeficiency MetaADEDB
Impotence ADReCS
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Perforation MetaADEDB
Ischias MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Joint Effusion MetaADEDB
Joint Ligament Rupture MetaADEDB
Joint Sprain MetaADEDB
Kaposi Sarcoma MetaADEDB
Lacunar Infarction MetaADEDB
Leukoaraiosis MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Ligament Rupture MetaADEDB
Limb Operation MetaADEDB
Liver Operation MetaADEDB
Local Swelling MetaADEDB
Localised Oedema MetaADEDB
Localised Osteoarthritis MetaADEDB
Loss Of Weight MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Lung Injury MetaADEDB
Lung Transplant MetaADEDB
Mastoiditis MetaADEDB
Medical Device Implantation MetaADEDB
Melanocytic Naevus MetaADEDB
Meningitis Bacterial MetaADEDB
Microalbuminuria MetaADEDB
Microvascular Angina MetaADEDB
Micturition Disorder MetaADEDB
Mitral Valve Calcification MetaADEDB
Movement Disorder MetaADEDB
Multiple System Atrophy MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Muscle Strain MetaADEDB
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Myasthenia Gravis MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myelodysplasia MetaADEDB
Myopia MetaADEDB
Nausea ADReCS
Necrolysis Epidermal SIDER
Nephrogenic Diabetes Insipidus MetaADEDB
Nephrosis Lipoid MetaADEDB
Nephrotic Syndrome MetaADEDB
Nervous Tension MetaADEDB
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
Nodule MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Oliguria MetaADEDB
Open Wound MetaADEDB
Oral Mucosal Petechiae MetaADEDB
Oropharyngeal Candidiasis MetaADEDB
Oropharyngeal Pain MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis MetaADEDB
Osteoporosis MetaADEDB
Pallor MetaADEDB
Pancreatitis ADReCS
Pancreatitis Acute Necrotizing MetaADEDB
Pancreatitis Chronic MetaADEDB
Paraesthesia ADReCS
Paraesthesia Oral MetaADEDB
Parathyroid Tumour MetaADEDB
Parkinson MetaADEDB
Penile Haemorrhage MetaADEDB
Pericardial Effusion MetaADEDB
Periodontitis MetaADEDB
Peripheral Nerve Lesion MetaADEDB
Peroneal Nerve Palsy MetaADEDB
Petechia MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pigmentation Disorder MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumothorax MetaADEDB
Polyp Colorectal MetaADEDB
Polyuria MetaADEDB
Post Laminectomy Syndrome MetaADEDB
Post Procedural Complication MetaADEDB
Presbyopia MetaADEDB
Proteinuria MetaADEDB
Purpura ADReCS
Rales MetaADEDB
Rash ADReCS
Raynaud Phenomenon MetaADEDB
Renal Cyst MetaADEDB
Renal Insufficiency MetaADEDB
Respiratory Failure MetaADEDB
Restlessness ADReCS
Retinal Bleeding MetaADEDB
Rhabdomyolysis MetaADEDB
Rheumatic Fever MetaADEDB
Septic Arthritis Staphylococcal MetaADEDB
Skin Discolouration MetaADEDB
Skin Tightness MetaADEDB
Snoring MetaADEDB
Social Avoidant Behaviour ADReCS
Spinal Cord Compression MetaADEDB
Spontaneous Penile Erection MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Stem Cell Transplant MetaADEDB
Stent Placement MetaADEDB
Stroke MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subdural Haemorrhage MetaADEDB
Suicidal Behaviour MetaADEDB
Superior Vena Cava Syndrome MetaADEDB
Tachycardia MetaADEDB
Thrombocytopenia ADReCS
Thyroid Disease MetaADEDB
Thyroidectomy MetaADEDB
Toe Amputation MetaADEDB
Toe Operation MetaADEDB
Tooth Impacted MetaADEDB
Tooth Loss MetaADEDB
Torsades De Pointes MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Transient Ischaemic Attack MetaADEDB
Upper Limb Fracture MetaADEDB
Uraemic Encephalopathy MetaADEDB
Urine Calcium MetaADEDB
Urosepsis MetaADEDB
Urticaria ADReCS
Varicose Vein MetaADEDB
Vascular Pseudoaneurysm MetaADEDB
Vascular Purpura ADReCS
Vasculitis ADReCS
Vasculitis Necrotising ADReCS
Ventricular Hypokinesia MetaADEDB
Ventricular Premature Complexes MetaADEDB
Vertigo ADReCS
Vomiting ADReCS
Weakness SIDER
Withdrawn SIDER
Wound Infection Staphylococcal MetaADEDB
Xanthopsia ADReCS
Xerostomia MetaADEDB

InAADR: Drug-Protein-ADRs database