InAADR

Drug Information

Drug Name: Paromomycin (7542-37-2)
PubChem ID: 165580
SMILES: C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N
InchiKey: UOZODPSAJZTQNH-LSWIJEOBSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 615.634
LogP: -8.8617
Ring Count: 0
Hydrogen Bond Acceptor Count: 19
Hydrogen Bond Donor Count: 13
Total Polar Surface Area: 347.32

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Methotrexate (59-05-2) Malabsorption Syndrome Antagonistic Oral aminoglycosides reduce the activity of the gut flora, which metabolise methotrexate so that more is available for absorption. Malabsorption due to paromomycin

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

InAADR: Drug-Protein-ADRs database