InAADR

Drug Information

Drug Name: Colchicine (64-86-8)
PubChem ID: 6167
SMILES: CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
InchiKey: IAKHMKGGTNLKSZ-INIZCTEOSA-N
Therapeutic Category: Antimitotic Agents, Antirheumatic Agents, Gout Suppressants, Mitosis Modulators, Tubulin Modulators

Computed Drug Properties

Molecular Weight (dalton): 399.443
LogP: 2.8716
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 83.09

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Bone Marrow Toxicity Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp ADReCS
Abdominal Cramp SIDER
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Abnormal Eeg MetaADEDB
Abnormalities Drug-Induced MetaADEDB
Accident MetaADEDB
Acetonaemic Vomiting MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acid Reflux MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Pancreatitis MetaADEDB
Afib MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased ADReCS
Allergic Vasculitis MetaADEDB
Alopecia ADReCS
Alveolitis MetaADEDB
Alzheimer Disease MetaADEDB
Amnesia MetaADEDB
Amyloidosis MetaADEDB
Anaemia ADReCS
Anemia MetaADEDB
Anemia Megaloblastic MetaADEDB
Aneurysm MetaADEDB
Angina MetaADEDB
Anhedonia MetaADEDB
Anorexia MetaADEDB
Anuria MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aphasia Broca MetaADEDB
Aplastic Anaemia ADReCS
Application Site Dermatitis MetaADEDB
Arrhythmias Cardiac MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriovenous Fistula Thrombosis MetaADEDB
Arteriovenous Malformation MetaADEDB
Arthritis Gouty MetaADEDB
Arthritis Psoriatic MetaADEDB
Arthritis Rheumatoid MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atonic Urinary Bladder MetaADEDB
Atrial Flutter MetaADEDB
Aura MetaADEDB
Autoimmune Disorder MetaADEDB
Avascular Necrosis MetaADEDB
Azoospermia ADReCS
Azotaemia MetaADEDB
Back Ache MetaADEDB
Bacterial Toxaemia MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Basedow Disease MetaADEDB
Behcet Syndrome MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Blister MetaADEDB
Blood 125-Dihydroxycholecalciferol Decreased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Uric Acid MetaADEDB
Bone Marrow Diseases MetaADEDB
Bone Marrow Failure ADReCS
Bone Marrow Toxicity MetaADEDB
Bone Pain MetaADEDB
Bradycardia MetaADEDB
Brain Diseases MetaADEDB
Brain Injuries MetaADEDB
Brain Oedema MetaADEDB
Breast Cyst MetaADEDB
Breast Induration MetaADEDB
Breast Swelling MetaADEDB
Bronchitis MetaADEDB
Bruise MetaADEDB
Calcinosis MetaADEDB
Calciphylaxis MetaADEDB
Candida Infection MetaADEDB
Carcinoma Hepatocellular MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Ischemia MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomyopathy MetaADEDB
Cardiovascular Disorder ADReCS
Cellulitis MetaADEDB
Cerebral Haemorrhage MetaADEDB
Chest Pain MetaADEDB
Chicken Pox MetaADEDB
Chlamydial Infection MetaADEDB
Choking Sensation MetaADEDB
Cholestasis MetaADEDB
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Cirrhosis MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Clotting MetaADEDB
Clumsiness MetaADEDB
Cmv Infection MetaADEDB
Cognition Disorders MetaADEDB
Cognitive Disorder MetaADEDB
Colostomy MetaADEDB
Concomitant Disease Aggravated MetaADEDB
Condylomata Acuminata MetaADEDB
Confabulation MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Conjunctival Deposit MetaADEDB
Continuous Haemodiafiltration MetaADEDB
Convulsions Grand Mal MetaADEDB
Crackles Lung MetaADEDB
Cramp Muscle SIDER
Creatine Phosphokinase Increased SIDER
Cytolytic Hepatitis ADReCS
Dehydration MetaADEDB
Demyelination MetaADEDB
Dermatitis ADReCS
Diabetes MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Difficulty In Walking MetaADEDB
Discomfort ADReCS
Disorder Lung MetaADEDB
Disseminated Intravascular Coagulation ADReCS
Diverticulitis MetaADEDB
Diverticulum MetaADEDB
Dizziness MetaADEDB
Down Syndrome MetaADEDB
Drug Administered At Inappropriate Site MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Dry Skin MetaADEDB
Dyspnea MetaADEDB
Dyspnea Exertional MetaADEDB
Ear Ache MetaADEDB
Ear Infection MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Abnormal MetaADEDB
Electromechanical Dissociation MetaADEDB
Elevated Triglycerides MetaADEDB
Embolism Air MetaADEDB
Emotional Distress MetaADEDB
Enlarged Spleen MetaADEDB
Enteritis MetaADEDB
Enterocolitis MetaADEDB
Epistaxis MetaADEDB
Eruption MetaADEDB
Excess Potassium MetaADEDB
Extrasystoles MetaADEDB
Extremity Pain MetaADEDB
Eye Pain MetaADEDB
Faecal Incontinence MetaADEDB
Faeces Discoloured MetaADEDB
Familial Mediterranean Fever MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fib MetaADEDB
Flat Affect MetaADEDB
Flu MetaADEDB
Fluid Overload MetaADEDB
Gallbladder Diseases MetaADEDB
Gangrene MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Diseases MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gastrointestinal Toxicity MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Anxiety Disorder MetaADEDB
Genital Burning Sensation MetaADEDB
Gingival Disorder MetaADEDB
Glaucoma Open-Angle MetaADEDB
Glomerulonephritis MetaADEDB
Gout ADReCS
Gout Flare SIDER
Granulocytopenia ADReCS
Granulocytosis MetaADEDB
Guillain-Barre Syndrome MetaADEDB
Haematemesis MetaADEDB
Haemoglobin ADReCS
Haemoglobinuria MetaADEDB
Haemorrhage ADReCS
Haemorrhagic Hepatic Cyst MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Hemiparesis MetaADEDB
Hemiplegia MetaADEDB
Hemorrhage MetaADEDB
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatic Trauma MetaADEDB
Hepatitis MetaADEDB
Hepatitis A MetaADEDB
Hepatitis B Chronic MetaADEDB
Hepatocellular Injury ADReCS
Hepatosplenomegaly MetaADEDB
Hernia Hiatal MetaADEDB
Hip Fracture MetaADEDB
Hyperalimentation MetaADEDB
Hyperammonaemic Encephalopathy MetaADEDB
Hyperkeratosis MetaADEDB
Hyperkinesis MetaADEDB
Hyperlipaemia MetaADEDB
Hypernatremia MetaADEDB
Hyperpigmentation MetaADEDB
Hypersexuality MetaADEDB
Hypertension MetaADEDB
Hypertonia MetaADEDB
Hypertransaminasaemia MetaADEDB
Hyperuricemia MetaADEDB
Hypokalaemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hyponatremia MetaADEDB
Hypoprothrombinaemia MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypotrichosis MetaADEDB
Hypoxia MetaADEDB
Immunosuppression MetaADEDB
Impulse-Control Disorder MetaADEDB
Incontinence MetaADEDB
Incorrect Dose Administered MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Inflammation MetaADEDB
Infusion Related Reaction MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Insulin-Requiring Type 2 Diabetes Mellitus MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intestinal Diseases MetaADEDB
Iris Disorder MetaADEDB
Iron Overload MetaADEDB
Jaundice MetaADEDB
Joint Contracture MetaADEDB
Joint Effusion MetaADEDB
Joint Lock MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Joint Stiffness MetaADEDB
Kidney Diseases MetaADEDB
Kidney Transplant MetaADEDB
Lactose Intolerance ADReCS
Large Intestine Perforation MetaADEDB
Learning Disorders MetaADEDB
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukemia Myelomonocytic Acute MetaADEDB
Leukopenia ADReCS
Liver Diseases MetaADEDB
Liver Diseases Alcoholic MetaADEDB
Liver Disorder ADReCS
Liver Failure Acute MetaADEDB
Liver Injury ADReCS
Localised Infection MetaADEDB
Lower Respiratory Tract Infection Viral MetaADEDB
Lymphedema MetaADEDB
Major Depression MetaADEDB
Mediastinal Disorder SIDER
Memory Disorders MetaADEDB
Mental Disorder MetaADEDB
Mental Status Changes MetaADEDB
Migraine With Aura MetaADEDB
Miosis MetaADEDB
Mononeuropathy MetaADEDB
Moraxella Infection MetaADEDB
Mouth Bleeding MetaADEDB
Mucosal Erosion MetaADEDB
Mucous Membrane Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Myeloma MetaADEDB
Multiple Organ Failure MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Atrophy MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness MetaADEDB
Myalgia ADReCS
Mycobacterium Avium Complex Infection MetaADEDB
Myelosuppression SIDER
Myoglobin Blood Increased MetaADEDB
Myoglobinuria MetaADEDB
Myopathy ADReCS
Myopathy Toxic MetaADEDB
Myotonia ADReCS
Myotonic Disorders MetaADEDB
Nasopharyngeal Cancer MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Necrosis MetaADEDB
Nephroangiosclerosis MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nervous System Diseases MetaADEDB
Nervous System Disorder ADReCS
Neumonia MetaADEDB
Neural Tube Defects MetaADEDB
Neuritis ADReCS
Neuromuscular Diseases MetaADEDB
Neuropathic Pain MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Nipple Disorder MetaADEDB
Nipple Swelling MetaADEDB
Non-Hodgkin Lymphoma MetaADEDB
Ocular Icterus MetaADEDB
Off Label Use MetaADEDB
Oligospermia SIDER
Oliguria MetaADEDB
Optic Atrophy MetaADEDB
Optic Nerve Diseases MetaADEDB
Oropharyngeal Discomfort MetaADEDB
Oropharyngeal Pain ADReCS
Orthopnea MetaADEDB
Overdose MetaADEDB
Pain MetaADEDB
Pain Exacerbated MetaADEDB
Pancreatitis MetaADEDB
Pancytopenia ADReCS
Paralysis MetaADEDB
Paronychia MetaADEDB
Pemphigus MetaADEDB
Penile Oedema MetaADEDB
Pericardial Effusion MetaADEDB
Pericarditis MetaADEDB
Peripheral Motor Neuropathy ADReCS
Peripheral Nervous System Diseases MetaADEDB
Peripheral Sensorimotor Neuropathy ADReCS
Peritonitis Bacterial MetaADEDB
Pharyngitis Bacterial MetaADEDB
Pharyngolaryngeal Pain SIDER
Pitting Oedema MetaADEDB
Pneumothorax MetaADEDB
Polyneuropathies MetaADEDB
Polyuria MetaADEDB
Porphyria Cutanea Tarda MetaADEDB
Productive Cough MetaADEDB
Propofol Infusion Syndrome MetaADEDB
Psoriasis MetaADEDB
Psychoses MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Purpura ADReCS
Pyoderma Gangrenosum MetaADEDB
Quadriplegia MetaADEDB
Quality Of Life Decreased MetaADEDB
Rash ADReCS
Rash Maculo-Papular ADReCS
Reflex Abnormal MetaADEDB
Renal Cyst MetaADEDB
Renal Impairment MetaADEDB
Renal Injury ADReCS
Renal Insufficiency MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Insufficiency MetaADEDB
Retinal Artery Occlusion MetaADEDB
Retroperitoneal Haematoma MetaADEDB
Rhabdomyolysis ADReCS
Rheumatoid Lung MetaADEDB
Rhinorrhea MetaADEDB
Rib Fracture MetaADEDB
Scar MetaADEDB
Scratch MetaADEDB
Seizures MetaADEDB
Sensory Loss MetaADEDB
Sepsis MetaADEDB
Septic Shock MetaADEDB
Serositis MetaADEDB
Serum Ferritin Increased MetaADEDB
Shock Haemorrhagic MetaADEDB
Shwartzman Phenomenon MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration MetaADEDB
Skin Diseases MetaADEDB
Skin Fibrosis MetaADEDB
Skin Hypertrophy MetaADEDB
Skin Induration MetaADEDB
Skin Lesion MetaADEDB
Skin Plaque MetaADEDB
Skin Tightness MetaADEDB
Sleep Apnea MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Stent Placement MetaADEDB
Stomatitis Aphthous MetaADEDB
Striatonigral Degeneration MetaADEDB
Sweet Syndrome MetaADEDB
Tachycardia Sinus MetaADEDB
Tendon Disorder MetaADEDB
Tension Headache MetaADEDB
Terminal State MetaADEDB
Thrombocytopenia ADReCS
Toe Amputation MetaADEDB
Torsade De Pointes MetaADEDB
Transient Ischaemic Attack MetaADEDB
Treatment Noncompliance MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urinary Tract Infection Fungal MetaADEDB
Vacuolar Myopathy MetaADEDB
Vascular Purpura ADReCS
Venous Pressure Jugular Abnormal MetaADEDB
Viral Upper Respiratory Tract Infection MetaADEDB
Vision Disorders MetaADEDB
Vitamin B 12 Deficiency MetaADEDB
Vomiting ADReCS
Weakness SIDER
Weight Loss MetaADEDB

InAADR: Drug-Protein-ADRs database