InAADR

Drug Information

Drug Name: Chlorothiazide (58-94-6)
PubChem ID: 2720
SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2
InchiKey: JBMKAUGHUNFTOL-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 295.729
LogP: 0.1299
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 118.69

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension MetaADEDB
Abdominal Infection MetaADEDB
Abnormal Ecg MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Acute Graft Versus Host Disease In Liver MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Adenovirus Infection MetaADEDB
Adynamic Ileus MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Alopecia ADReCS
Alpha Tumour Necrosis Factor Increased MetaADEDB
Als MetaADEDB
Alveolitis MetaADEDB
Amentia MetaADEDB
Anaemia ADReCS
Anal Fissure MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angina Unstable MetaADEDB
Anhedonia MetaADEDB
Anhidrosis MetaADEDB
Anorexia ADReCS
Anxiety MetaADEDB
Aortic Aneurysm MetaADEDB
Aplastic Anaemia ADReCS
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Thrombosis Limb MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Aspiration Bone Marrow MetaADEDB
Asthenia ADReCS
Atelectasis MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Septal Defect MetaADEDB
Azotaemia MetaADEDB
Azotemia MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Barbiturates ADReCS
Bedridden MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Birth Defect MetaADEDB
Bladder Inflammation MetaADEDB
Bleeding Hemorrhoids MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Ph Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Uric Acid Increased ADReCS
Blood Urine Present MetaADEDB
Body Temperature Increased ADReCS
Bone Density Decreased MetaADEDB
Bone Pain MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Brain Neoplasm MetaADEDB
Bronchial Hyperactivity MetaADEDB
Bronchopneumonia MetaADEDB
Capillary Leak Syndrome MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebellar Ischaemia MetaADEDB
Cerebral Dysgenesis MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Ventricle Dilatation MetaADEDB
Choking Sensation MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Chylothorax MetaADEDB
Colonic Pseudo-Obstruction MetaADEDB
Condition Aggravated MetaADEDB
Congenital Pulmonary Hypertension MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congenital Ventricular Septal Defect MetaADEDB
Constipation ADReCS
Continuous Haemodiafiltration MetaADEDB
Convulsion MetaADEDB
Cor Pulmonale MetaADEDB
Craniotabes MetaADEDB
Csf Pressure Increased MetaADEDB
Csf Protein MetaADEDB
Cutaneous Vasculitis ADReCS
Death Of Child MetaADEDB
Decreased Appetite ADReCS
Dehydration MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative ADReCS
Diabetes Insipidus MetaADEDB
Dialysis MetaADEDB
Diaphragmatic Hernia MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Disease Of Liver MetaADEDB
Disorder Lung MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Dysmorphism MetaADEDB
Dysuria MetaADEDB
Ear Infection MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Echocardiogram Abnormal MetaADEDB
Economic Problem MetaADEDB
Electrolyte Imbalance ADReCS
Electromechanical Dissociation MetaADEDB
Emesis MetaADEDB
Encephalopathy MetaADEDB
Endarterectomy MetaADEDB
Endotracheal Intubation MetaADEDB
Engraftment Syndrome MetaADEDB
Enlarged Liver MetaADEDB
Enteritis MetaADEDB
Enterococcal Bacteraemia MetaADEDB
Enterococcal Infection MetaADEDB
Enterocolitis MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Erectile Dysfunction ADReCS
Erythema ADReCS
Erythema Infectiosum MetaADEDB
Erythema Multiforme ADReCS
Extrasystoles Ventricular MetaADEDB
Febrile Neutropenia MetaADEDB
Floaters MetaADEDB
Fluid Overload MetaADEDB
Formication MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Hypomotility MetaADEDB
General Physical Health Deterioration MetaADEDB
General Symptom MetaADEDB
Glaucoma MetaADEDB
Glycosuria ADReCS
Gout MetaADEDB
Graft Complication MetaADEDB
Haematoma MetaADEDB
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemolysis MetaADEDB
Haemolytic Anaemia ADReCS
Haemorrhage Rectum MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Hematoma Subdural MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Infarction MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis MetaADEDB
Hepatitis A Antibody MetaADEDB
Hepatocellular Injury MetaADEDB
Hepatosplenomegaly MetaADEDB
Hodgkin Disease Stage Iv MetaADEDB
Hospitalisation MetaADEDB
Humerus Fracture MetaADEDB
Hydronephrosis MetaADEDB
Hyperaesthesia MetaADEDB
Hypercalcemia MetaADEDB
Hypercalciuria MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis MetaADEDB
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hyperuricaemia ADReCS
Hypokalaemia MetaADEDB
Hypokalemia MetaADEDB
Hyponatremia MetaADEDB
Hypotension ADReCS
Hypoxia MetaADEDB
Iliac Artery Thrombosis MetaADEDB
Impotence ADReCS
Incorrect Dose Administered MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Inguinal Hernia Repair MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Iron Overload MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Jaw Disorder MetaADEDB
Kidney Calculi MetaADEDB
Kidney Failure MetaADEDB
Kidney Infection MetaADEDB
Klebsiella Bacteraemia MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Lethargy MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Liver Transplant MetaADEDB
Loss Of Weight MetaADEDB
Lung Edema MetaADEDB
Lung Injury MetaADEDB
Malnourished MetaADEDB
Meningitides MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Disorder MetaADEDB
Movement Disorder MetaADEDB
Multiple Fractures MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Disorder MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Muscle Strain MetaADEDB
Muscular Weakness ADReCS
Narcotic Intoxication ADReCS
Nasal Congestion MetaADEDB
Nausea ADReCS
Nephritis ADReCS
Nephropathy Toxic MetaADEDB
Nervous Tension MetaADEDB
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutrophil Count Decreased MetaADEDB
No Therapeutic Response MetaADEDB
Noonan Syndrome MetaADEDB
Obstruction MetaADEDB
Oliguria MetaADEDB
Optic Disc Edema MetaADEDB
Orthopnea MetaADEDB
Osteopenia MetaADEDB
Pain MetaADEDB
Pancreas Lipomatosis MetaADEDB
Pancreatitis ADReCS
Pancreatitis Acute Necrotizing MetaADEDB
Paraesthesia ADReCS
Paresis MetaADEDB
Patent Ductus Arteriosis MetaADEDB
Pericardial Effusion MetaADEDB
Persistent Foetal Circulation MetaADEDB
Photosensitivity Reaction ADReCS
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia ADReCS
Pneumonia Klebsiella MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumonitis ADReCS
Po2 MetaADEDB
Polyuria MetaADEDB
Portal Vein Thrombosis MetaADEDB
Posturing MetaADEDB
Premature Baby MetaADEDB
Primary Mediastinal Large B-Cell Lymphoma MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Hypoplasia MetaADEDB
Pulmonary Malformation MetaADEDB
Pulmonary Oedema ADReCS
Pulmonary Valve Stenosis MetaADEDB
Purpura ADReCS
Pyrexia ADReCS
Radius Fracture MetaADEDB
Rales MetaADEDB
Rash ADReCS
Renal Disorder ADReCS
Renal Failure ADReCS
Renal Haematoma MetaADEDB
Renal Injury MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Distress ADReCS
Respiratory Failure MetaADEDB
Respiratory Syncytial Virus Infection MetaADEDB
Restlessness ADReCS
Retinal Vascular Occlusion MetaADEDB
Rhabdomyolysis MetaADEDB
Right Ventricular Dysfunction MetaADEDB
Risus Sardonicus MetaADEDB
Septic Shock MetaADEDB
Serratia Bacteraemia MetaADEDB
Serratia Infection MetaADEDB
Sialoadenitis ADReCS
Social Avoidant Behaviour ADReCS
Speech Disorder MetaADEDB
Spleen Disorder MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Stevens-Johnson Syndrome ADReCS
Streptococcal Bacteraemia MetaADEDB
Stress MetaADEDB
Supraventricular Tachycardia MetaADEDB
Surgical Procedure Repeated MetaADEDB
Tendon Rupture MetaADEDB
Thrombocytopenia ADReCS
Thrombolysis MetaADEDB
Tibia Fracture MetaADEDB
Tinea Pedis MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Trisomy 21 MetaADEDB
Tubulointerstitial Nephritis ADReCS
Ulna Fracture MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Limb Fracture MetaADEDB
Urinary Tract Infection Pseudomonal MetaADEDB
Urticaria ADReCS
Vascular Purpura ADReCS
Vasculitis ADReCS
Vasculitis Necrotising ADReCS
Venoocclusive Disease MetaADEDB
Venous Thrombosis MetaADEDB
Vertebroplasty MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Wound MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB
Xanthopsia ADReCS

InAADR: Drug-Protein-ADRs database