| Drug Name: | Morphine (57-27-2) |
|---|---|
| PubChem ID: | 5288826 |
| SMILES: | CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O |
| InchiKey: | BQJCRHHNABKAKU-KBQPJGBKSA-N |
| Therapeutic Category: | Analgesics, Central Nervous System Agents, Central Nervous System Depressants, Narcotics, Peripheral Nervous System Agents, Sensory System Agents |
| Molecular Weight (dalton) | : | 285.343 |
| LogP | : | 1.1981 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 52.93 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Mexiletine (31828-71-4) | Myocardial Infarction | Antagonistic | Uncertain | A trial of intravenous and oral mexiletine in acute myocardial infarction |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Cardiac Arrhythmias | Mu-Type opioid receptor (P35372) | Morphine and morphiceptin increase the threshold for epinephrine-induced cardiac arrhythmias in the rat through brain mu opioid receptors [ ADR Type 3 ] | Morphine and morphiceptin increase the threshold for epinephrine-induced cardiac arrhythmias in the rat through brain mu opioid receptors |
| Constipation | Mu-Type opioid receptor (P35372) | Role of systems pharmacology in understanding drug adverse events |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category