InAADR

Drug Information

Drug Name: Epirubicin (56420-45-2)
PubChem ID: 41867
SMILES: C[C@H]1[C@@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
InchiKey: AOJJSUZBOXZQNB-VTZDEGQISA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 543.525
LogP: 0.0013
Ring Count: 2
Hydrogen Bond Acceptor Count: 12
Hydrogen Bond Donor Count: 6
Total Polar Surface Area: 206.07

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
verapamil (52-53-9) Bone Marrow Depression Antagonistic Not known Pharmacokinetic interaction between epirubicin and the multidrug resistance reverting agent D-verapamil

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Alopecia ADReCS
Amenorrhoea ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anemia MetaADEDB
Anemia Hemolytic MetaADEDB
Angioedema MetaADEDB
Anorexia ADReCS
Anuria MetaADEDB
Arteritis MetaADEDB
Asthenia MetaADEDB
Atrioventricular Block MetaADEDB
Bone Marrow Diseases MetaADEDB
Bone Marrow Failure ADReCS
Breast Neoplasms MetaADEDB
Carcinoma Ductal Breast MetaADEDB
Carcinoma Hepatocellular MetaADEDB
Carcinoma Non-Small-Cell Lung MetaADEDB
Cardiac Complexes Premature MetaADEDB
Cardiac Disorder ADReCS
Cardiac Failure Congestive ADReCS
Cardiomyopathies MetaADEDB
Cardiomyopathy Dilated MetaADEDB
Carotid Stenosis MetaADEDB
Chills ADReCS
Conjunctivitis ADReCS
Coronary Thrombosis MetaADEDB
Cystitis MetaADEDB
Decreased Appetite ADReCS
Dehydration ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Drug Toxicity ADReCS
Encephalitis Herpes Simplex MetaADEDB
Erythema MetaADEDB
Esophageal Neoplasms MetaADEDB
Fatigue MetaADEDB
Febrile Neutropenia ADReCS
Fever MetaADEDB
Flushing ADReCS
Gingival Hyperpigmentation ADReCS
Hair Disorder ADReCS
Head And Neck Neoplasms MetaADEDB
Heart Arrest MetaADEDB
Heart Diseases MetaADEDB
Heart Failure MetaADEDB
Hematuria MetaADEDB
Hemolytic-Uremic Syndrome MetaADEDB
Hemoptysis MetaADEDB
Hemorrhage MetaADEDB
Hodgkin Disease MetaADEDB
Hot Flush ADReCS
Hypersensitivity ADReCS
Hypotension MetaADEDB
Hypothyroidism MetaADEDB
Infection ADReCS
Kidney Diseases MetaADEDB
Lethargy ADReCS
Leukaemia ADReCS
Leukemia Promyelocytic Acute MetaADEDB
Leukopenia ADReCS
Liver Neoplasms MetaADEDB
Lung Neoplasms MetaADEDB
Lymphoma MetaADEDB
Lymphoma Non-Hodgkin MetaADEDB
Lymphoproliferative Disorders MetaADEDB
Melanoma MetaADEDB
Mucosal Inflammation ADReCS
Mucositis MetaADEDB
Myelodysplastic Syndrome ADReCS
Myocardial Infarction MetaADEDB
Myocardial Ischemia MetaADEDB
Nail Pigmentation ADReCS
Nausea ADReCS
Neoplasms Second Primary MetaADEDB
Nervous System Diseases MetaADEDB
Neuroectodermal Tumors Primitive Peripheral MetaADEDB
Neutropenia ADReCS
Ovarian Neoplasms MetaADEDB
Pain MetaADEDB
Paresthesia MetaADEDB
Penile Neoplasms MetaADEDB
Phlebitis MetaADEDB
Photosensitivity Reaction ADReCS
Prostatic Neoplasms MetaADEDB
Proteinuria MetaADEDB
Pruritus ADReCS
Pyrexia ADReCS
Pyuria MetaADEDB
Rash ADReCS
Rectal Neoplasms MetaADEDB
Sarcoma MetaADEDB
Sclerosis MetaADEDB
Sepsis MetaADEDB
Shock ADReCS
Skin Disorder ADReCS
Skin Reaction ADReCS
Small Cell Lung Carcinoma MetaADEDB
Stomach Neoplasms MetaADEDB
Stomatitis MetaADEDB
Tachycardia MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis MetaADEDB
Thrombosis MetaADEDB
Urinary Bladder Diseases MetaADEDB
Urinary Bladder Neoplasms MetaADEDB
Urination Disorders MetaADEDB
Urticaria ADReCS
Uterine Cervical Neoplasms MetaADEDB
Ventricular Dysfunction Left MetaADEDB
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database