InAADR

Drug Information

Drug Name: sunitinib (557795-19-4)
PubChem ID: 5329102
SMILES: CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
InchiKey: WINHZLLDWRZWRT-ATVHPVEESA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 398.482
LogP: 3.33494
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 77.23

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Bone Marrow Toxicity Grapefruit-medication interactions: forbidden fruit or avoidable consequences?
Grapefruit Juice Torsade De Pointes Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort SIDER
Abdominal Distension PROTECT
Abdominal Pain SIDER
Abdominal Pain SIDER
Acne PROTECT
Acute Coronary Syndrome SIDER
Adrenal Insufficiency SIDER
Ageusia SIDER
Alanine Aminotransferase Increased SIDER
Albumin Low SIDER
Alopecia SIDER
Amylase Increased SIDER
Anaemia SIDER
Anal Fistula PROTECT
Angioedema SIDER
Angiopathy SIDER
Anorexia SIDER
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aphthous Stomatitis SIDER
Apoptosis SIDER
Arrhythmia SIDER
Arthralgia SIDER
Aspartate Aminotransferase Increased SIDER
Asthenia SIDER
Back Pain SIDER
Blindness SIDER
Blindness Cortical SIDER
Blister SIDER
Blood Albumin Decreased SIDER
Blood Alkaline Phosphatase Increased SIDER
Blood Amylase Increased SIDER
Blood Bilirubin Increased SIDER
Blood Creatine Phosphokinase Increased PROTECT
Blood Creatinine Increased SIDER
Blood Glucose Decreased SIDER
Blood Glucose Increased SIDER
Blood Magnesium Decreased SIDER
Blood Phosphorus Decreased SIDER
Blood Potassium Decreased SIDER
Blood Potassium Increased SIDER
Blood Pressure Increased PROTECT
Blood Sodium Increased SIDER
Blood Thyroid Stimulating Hormone Increased SIDER
Blood Uric Acid Increased SIDER
Body Temperature Increased SIDER
Bradycardia SIDER
Ca++ Increased SIDER
Calcium Low SIDER
Cardiac Disorder PROTECT
Cardiac Failure SIDER
Cardiac Failure Congestive SIDER
Cell Death SIDER
Cerebral Infarction SIDER
Cerebrovascular Accident SIDER
Cheilitis PROTECT
Chest Pain SIDER
Chills SIDER
Chromaturia PROTECT
Congenital Skin Disorder SIDER
Connective Tissue Disorder SIDER
Constipation SIDER
Convulsion SIDER
Cough SIDER
Creatinine Increased SIDER
Cytolysis SIDER
Death ADReCS
Decreased Appetite SIDER
Deep Vein Thrombosis SIDER
Dehydration SIDER
Depressed Mood SIDER
Depression PROTECT
Dermatitis SIDER
Dermatitis Bullous SIDER
Dermatitis Psoriasiform SIDER
Diarrhoea SIDER
Discomfort SIDER
Dizziness SIDER
Dry Mouth SIDER
Dry Skin SIDER
Dysfunction Thyroid SIDER
Dysgeusia SIDER
Dyspepsia SIDER
Dysphagia PROTECT
Dyspnoea SIDER
Dyspnoea Exertional PROTECT
Eczema PROTECT
Ejection Fraction SIDER
Ejection Fraction Decreased SIDER
Electrocardiogram Pr Interval SIDER
Electrocardiogram Qt Prolonged PROTECT
Embolism SIDER
Embolism Venous ADReCS
Epistaxis SIDER
Eructation PROTECT
Erythema SIDER
Erythema Multiforme PROTECT
Eye Disorder SIDER
Eyelid Oedema PROTECT
Face Oedema PROTECT
Fatigue SIDER
Febrile Neutropenia SIDER
Feeling Abnormal ADReCS
Fistula SIDER
Flank Pain SIDER
Flatulence SIDER
Flushing PROTECT
Gastric Haemorrhage SIDER
Gastrointestinal Disorder SIDER
Gastrointestinal Pain SIDER
Gastrooesophageal Reflux Disease SIDER
Gingival Bleeding PROTECT
Gingival Pain SIDER
Gingivitis SIDER
Glossitis SIDER
Glossodynia SIDER
Glucose Decreased SIDER
Glucose Increased SIDER
Haematemesis SIDER
Haematochezia SIDER
Haematoma SIDER
Haemoglobin SIDER
Haemoglobin Decreased SIDER
Haemoptysis SIDER
Haemorrhage SIDER
Haemorrhoids SIDER
Hair Colour Changes SIDER
Hair Discoloration SIDER
Headache SIDER
Hepatic Failure SIDER
Hepatic Function Abnormal PROTECT
Hepatotoxicity ADReCS
Hot Flush PROTECT
Hyperaesthesia PROTECT
Hypercalcaemia SIDER
Hyperglycaemia SIDER
Hyperkalaemia SIDER
Hyperkeratosis PROTECT
Hypernatraemia SIDER
Hypersensitivity SIDER
Hypertension SIDER
Hyperthyroidism SIDER
Hyperuricaemia SIDER
Hypoaesthesia PROTECT
Hypoalbuminaemia SIDER
Hypocalcaemia SIDER
Hypogeusia SIDER
Hypoglycaemia SIDER
Hypokalaemia SIDER
Hyponatraemia SIDER
Hypophosphataemia SIDER
Hypothyroidism SIDER
Ill-Defined Disorder ADReCS
Impaired Healing PROTECT
Infarction SIDER
Infection SIDER
Infestation SIDER
Infestation Nos SIDER
Inflammation SIDER
Influenza SIDER
Influenza Like Illness SIDER
Insomnia SIDER
Intestinal Perforation PROTECT
Ischaemia SIDER
Lacrimation SIDER
Lacrimation Increased SIDER
Left Ventricular Dysfunction SIDER
Left Ventricular Ejection Fraction SIDER
Left Ventricular Failure PROTECT
Leukoderma SIDER
Leukoencephalopathy SIDER
Leukopenia SIDER
Lipase Increased SIDER
Liver Function Test Abnormal PROTECT
Lung Neoplasm Malignant SIDER
Lymphopenia SIDER
Malaise SIDER
Mediastinal Disorder SIDER
Melaena SIDER
Mental Disorder SIDER
Metastasis SIDER
Metrorrhagia SIDER
Mg Reduced SIDER
Microangiopathy SIDER
Mouth Ulceration SIDER
Mucosal Dryness SIDER
Mucosal Inflammation SIDER
Muscle Spasms PROTECT
Muscular Weakness PROTECT
Musculoskeletal Discomfort SIDER
Musculoskeletal Pain PROTECT
Myalgia SIDER
Myocardial Ischaemia SIDER
Myopathy SIDER
Nail Discolouration PROTECT
Nail Disorder PROTECT
Nasal Congestion PROTECT
Nasal Dryness PROTECT
Nasopharyngitis SIDER
Nausea SIDER
Necrosis SIDER
Neoplasm SIDER
Nephrotic Syndrome SIDER
Nervous System Disorder SIDER
Neuropathy SIDER
Neuropathy Peripheral SIDER
Neutropenia SIDER
Neutrophil Count Decreased PROTECT
Oedema SIDER
Oedema Peripheral SIDER
Oesophagitis SIDER
Oral Discomfort PROTECT
Oral Pain SIDER
Oropharyngeal Pain PROTECT
Pain SIDER
Pain In Extremity SIDER
Palmar-Plantar Erythrodysaesthesia Syndrome PROTECT
Pancreatic Disorder SIDER
Pancreatitis SIDER
Pancytopenia PROTECT
Paraesthesia PROTECT
Pericardial Effusion PROTECT
Periorbital Oedema SIDER
Phosphatase Alkaline Increased SIDER
Phosphorus Low SIDER
Pigmentation Disorder PROTECT
Platelet Count Decreased SIDER
Pleural Effusion PROTECT
Pneumonia PROTECT
Posterior Reversible Encephalopathy Syndrome SIDER
Potassium Increased SIDER
Potassium Low SIDER
Primary Hypothyroidism SIDER
Proctalgia PROTECT
Protein Urine Present SIDER
Proteinuria SIDER
Prurigo SIDER
Pruritus SIDER
Pulmonary Embolism SIDER
Pulmonary Haemorrhage SIDER
Pyoderma Gangrenosum PROTECT
Pyrexia PROTECT
Rash SIDER
Rash Erythematous SIDER
Rash Follicular SIDER
Rash Papular SIDER
Rash Psoriaform SIDER
Rectal Haemorrhage PROTECT
Reflux Oesophagitis SIDER
Regressive Behaviour SIDER
Renal Failure SIDER
Renal Failure Acute SIDER
Renal Impairment SIDER
Respiratory Tract Infection SIDER
Reversible Posterior Leukoencephalopathy Syndrome SIDER
Rhabdomyolysis SIDER
Seizures SIDER
Sickness SIDER
Skin Discolouration SIDER
Skin Exfoliation PROTECT
Skin Hyperpigmentation PROTECT
Skin Lesion PROTECT
Skin Reaction PROTECT
Skin Ulcer PROTECT
Social Avoidant Behaviour SIDER
Sodium Decreased SIDER
Sodium High SIDER
Solid Tumour SIDER
Splinter Haemorrhages SIDER
Stevens-Johnson Syndrome PROTECT
Stomatitis SIDER
Subclinical Hypothyroidism SIDER
Taste Altered SIDER
Thrombocytopenia SIDER
Thromboembolic Event SIDER
Thrombosis SIDER
Thrombotic Microangiopathy SIDER
Thyroid Disorder SIDER
Thyroiditis SIDER
Thyrotoxicosis SIDER
Thyrotropin High SIDER
Tongue Ulceration SIDER
Toxic Epidermal Necrolysis PROTECT
Transient Ischaemic Attack SIDER
Tumour Lysis Syndrome SIDER
Tumour Necrosis SIDER
Ulcer SIDER
Upper Respiratory Tract Infection SIDER
Venous Thrombosis SIDER
Ventricular Dysfunction SIDER
Visual Acuity Reduced SIDER
Visual Impairment SIDER
Vomiting SIDER
Weight Decreased SIDER
White Blood Cell Count Decreased PROTECT
Withdrawn SIDER
Wound Haemorrhage SIDER
Yellow Skin SIDER

InAADR: Drug-Protein-ADRs database