InAADR

Drug Information

Drug Name: Praziquantel (55268-74-1)
PubChem ID: 4891
SMILES: C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
InchiKey: FSVJFNAIGNNGKK-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 312.413
LogP: 2.5349
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 40.62

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Chloroquine (54-05-7) Reduced Pranziquantel Efficacy In Systemic Worm Infections Such As Schistosomiasis Antagonistic Not established The effect of chloroquine on the pharmacokinetics and metabolism of praziquantel in rats and in humans
Phenytoin (57-41-0) Neurocysticercosis Treatment Failures Antagonistic Not established Phenytoin and carbamazepine decreased oral bioavailability of praziquantel

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Anorexia ADReCS
Arrhythmia ADReCS
Asthenia ADReCS
Atrioventricular Block ADReCS
Body Temperature Increased ADReCS
Bradycardia ADReCS
Cardiac Disorder ADReCS
Cardiac Fibrillation ADReCS
Cardiovascular Diseases MetaADEDB
Central Nervous System Diseases MetaADEDB
Cerebral Infarction MetaADEDB
Cestode Infections MetaADEDB
Convulsion ADReCS
Cysticercosis MetaADEDB
Death ADReCS
Decreased Appetite ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diarrhoea Haemorrhagic ADReCS
Diphyllobothriasis MetaADEDB
Discomfort ADReCS
Dizziness ADReCS
Dog Diseases MetaADEDB
Drowsiness SIDER
Drug-Induced Liver Injury MetaADEDB
Eosinophilia ADReCS
Feeling Abnormal ADReCS
Gastritis MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Giardiasis MetaADEDB
Headache ADReCS
Helminthiasis MetaADEDB
Hepatic Impairment ADReCS
Hymenolepiasis MetaADEDB
Hypersensitivity ADReCS
Ill-Defined Disorder ADReCS
Immune System Disorder SIDER
Infestation SIDER
Infestation Nos SIDER
Intestinal Diseases Parasitic MetaADEDB
Intracranial Hypertension MetaADEDB
Liver Disorder ADReCS
Malaise ADReCS
Mental Disorders MetaADEDB
Muscular Diseases MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Nausea ADReCS
Nematode Infections MetaADEDB
Nervous System Diseases MetaADEDB
Nervous System Disorder SIDER
Neurocysticercosis MetaADEDB
Obstruction ADReCS
Opisthorchiasis MetaADEDB
Pain ADReCS
Paresthesia MetaADEDB
Polyserositis ADReCS
Schistosomiasis MetaADEDB
Schistosomiasis Japonica MetaADEDB
Schistosomiasis Mansoni MetaADEDB
Seizures SIDER
Skin Diseases MetaADEDB
Somnolence ADReCS
Tachycardia MetaADEDB
Taeniasis MetaADEDB
Trematode Infections MetaADEDB
Urticaria ADReCS
Ventricular Fibrillation ADReCS
Vertigo ADReCS
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database