InAADR

Drug Information

Drug Name: Trimetazidine (5011-34-7)
PubChem ID: 21109
SMILES: COC1=C(C(=C(C=C1)CN2CCNCC2)OC)OC
InchiKey: UHWVSEOVJBQKBE-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 266.341
LogP: 1.1176
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 42.96

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abnormal Ecg MetaADEDB
Abnormal Eeg MetaADEDB
Accelerated Hypertension MetaADEDB
Acquired Haemophilia MetaADEDB
Acute Coronary Syndrome MetaADEDB
Acute Febrile Neutrophilic Dermatosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenopathy MetaADEDB
Adh Inappropriate MetaADEDB
Adrenocortical Insufficiency Acute MetaADEDB
Afib MetaADEDB
Aggression MetaADEDB
Agranulocytoses MetaADEDB
Agraphia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Vasculitis MetaADEDB
Amentia MetaADEDB
Amnestic Disorder MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Angina MetaADEDB
Angina Pectoris MetaADEDB
Angina Unstable MetaADEDB
Angiogram MetaADEDB
Angioplasty MetaADEDB
Angle Closure Glaucoma MetaADEDB
Ankylosing Spondylitis MetaADEDB
Antinuclear Antibody MetaADEDB
Anuria MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Dilatation MetaADEDB
Apathy MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Apparent Death MetaADEDB
Apraxia MetaADEDB
Arrhythmia Supraventricular MetaADEDB
Arrhythmias Cardiac MetaADEDB
Arterial Disorder MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Thrombosis MetaADEDB
Arteriogram Coronary Abnormal MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthmatic Crisis MetaADEDB
Asystole MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block MetaADEDB
Atrioventricular Block Complete MetaADEDB
Atrioventricular Block Second Degree MetaADEDB
Aura MetaADEDB
Basedow Disease MetaADEDB
Benign Small Intestinal Neoplasm MetaADEDB
Beta 2 Microglobulin Increased MetaADEDB
Bile Duct Obstruction MetaADEDB
Biliary Adenoma MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Blood Bicarbonate Abnormal MetaADEDB
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Immunoglobulin E MetaADEDB
Blood In Urine MetaADEDB
Blood Iron Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bradycardia MetaADEDB
Brain Damage MetaADEDB
Brain Herniation MetaADEDB
Brain Scan Abnormal MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchitis MetaADEDB
Bundle Branch Block Left MetaADEDB
Bundle Branch Block Right MetaADEDB
C-Reactive Protein Increased MetaADEDB
Calcinosis MetaADEDB
Capillary Leak Syndrome MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Ventriculogram Left MetaADEDB
Cardiogenic Shock MetaADEDB
Cardioversion MetaADEDB
Causalgia MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Atrophy MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Cholangitis Sclerosing MetaADEDB
Cholecystitis Acute MetaADEDB
Choroidal Effusion MetaADEDB
Chromaturia MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Chronic Obstructive Airways Disease Exacerbated MetaADEDB
Colitis Ischaemic MetaADEDB
Colonic Obstruction MetaADEDB
Colorectal Cancer MetaADEDB
Coma MetaADEDB
Confabulation MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Constipated MetaADEDB
Conversion Disorder MetaADEDB
Coronary Artery Stenosis MetaADEDB
Creatinine Renal Clearance Decreased MetaADEDB
Cutaneous Vasculitis MetaADEDB
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Colitis MetaADEDB
Deafness Unilateral MetaADEDB
Dehydration MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Exfoliative MetaADEDB
Device Ineffective MetaADEDB
Diaphragmatic Paralysis MetaADEDB
Diarrhea MetaADEDB
Diffuse Large B-Cell Lymphoma Stage Ii MetaADEDB
Dilatation Ventricular MetaADEDB
Disorder Lung MetaADEDB
Diverticulitis MetaADEDB
Dressler Syndrome MetaADEDB
Drowsiness MetaADEDB
Drug Interaction MetaADEDB
Duodenitis MetaADEDB
Dysphonia MetaADEDB
Ecg Signs Of Myocardial Ischaemia MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Elevated Triglycerides MetaADEDB
Encephalopathy MetaADEDB
Enlarged Liver MetaADEDB
Enterovesical Fistula MetaADEDB
Eosinophil Count Increased MetaADEDB
Erysipelas MetaADEDB
Erythremia MetaADEDB
Eschar MetaADEDB
Esophageal Ulcer MetaADEDB
Excess Potassium MetaADEDB
Excessive Sleepiness MetaADEDB
External Ear Infection MetaADEDB
Extrapyramidal Disorder MetaADEDB
Face Injury MetaADEDB
Faecaloma MetaADEDB
Feeding Tube Insertion MetaADEDB
Flatulence MetaADEDB
Fluid Intake Restriction MetaADEDB
Folliculitis MetaADEDB
Foot Amputation MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gammopathy MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gaze Palsy MetaADEDB
General Physical Health Deterioration MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephritis Proliferative MetaADEDB
Glossitis MetaADEDB
Gouty Arthritis MetaADEDB
Granulomatous Liver Disease MetaADEDB
Gynaecomastia MetaADEDB
Haemarthrosis MetaADEDB
Haematemesis MetaADEDB
Haematoma MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhage Rectum MetaADEDB
Haptoglobin Decreased MetaADEDB
Head Injury MetaADEDB
Hematoma Subdural MetaADEDB
Hemianopia MetaADEDB
Hemiplegia MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Fibrosis MetaADEDB
Hepatic Pain MetaADEDB
Hepatitis MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatocellular Injury MetaADEDB
Hiccough MetaADEDB
Hip Arthroplasty MetaADEDB
Humerus Fracture MetaADEDB
Hyaluronic Acid Increased MetaADEDB
Hydrothorax MetaADEDB
Hyperammonaemia MetaADEDB
Hyperamylasaemia MetaADEDB
Hypercapnia MetaADEDB
Hyperreflexia MetaADEDB
Hypokalaemia MetaADEDB
Hypoproteinaemia MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypotonia MetaADEDB
Hypoxia MetaADEDB
Ild MetaADEDB
Immunoglobulins Increased MetaADEDB
Incoherent MetaADEDB
Increased Platelet Count MetaADEDB
Infected Skin Ulcer MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Intra-Aortic Balloon Placement MetaADEDB
Intracranial Haematoma MetaADEDB
Iridocyclitis MetaADEDB
Ischaemic Stroke MetaADEDB
Itch MetaADEDB
Joint Fluid Drainage MetaADEDB
Kaposi Sarcoma MetaADEDB
Kidney Diseases MetaADEDB
Kidney Failure MetaADEDB
Leucopenia MetaADEDB
Leukoencephalopathy MetaADEDB
Lichenoid Keratosis MetaADEDB
Lipase MetaADEDB
Localised Oedema MetaADEDB
Localised Osteoarthritis MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infection MetaADEDB
Lyell MetaADEDB
Lymphocytes Decreased MetaADEDB
Macrocytosis MetaADEDB
Macular Hole MetaADEDB
Meningoradiculitis MetaADEDB
Microlithiasis MetaADEDB
Miosis MetaADEDB
Morganella Infection MetaADEDB
Motor Dysfunction MetaADEDB
Motor Retardation MetaADEDB
Mouth Bleeding MetaADEDB
Mucous Membrane Disorder MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Necrosis MetaADEDB
Myasthenia Gravis MetaADEDB
Myocardial Ischemia MetaADEDB
Myoglobin Blood Increased MetaADEDB
Near Syncope MetaADEDB
Neoplasm Prostate MetaADEDB
Neovascularisation MetaADEDB
Neuroendocrine Carcinoma MetaADEDB
Neutrophil Count Abnormal MetaADEDB
Normal Pressure Hydrocephalus MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Obesity Surgery MetaADEDB
Obstructive Airways Disorder MetaADEDB
Optic Disc Edema MetaADEDB
Oral Mucosa Erosion MetaADEDB
Oral Mucosal Exfoliation MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain MetaADEDB
Pallor MetaADEDB
Pancreatic Cyst MetaADEDB
Pancreatic Enzymes Increased MetaADEDB
Pancreatic Neoplasm MetaADEDB
Paraneoplastic Syndrome MetaADEDB
Parkinsonian Gait MetaADEDB
Pemphigus MetaADEDB
Pericarditis MetaADEDB
Peritoneal Effusion MetaADEDB
Photodermatosis MetaADEDB
Plasmacytosis MetaADEDB
Platelet Count MetaADEDB
Pleurisy MetaADEDB
Pneumaturia MetaADEDB
Pneumonia Haemophilus MetaADEDB
Pneumonia Necrotising MetaADEDB
Polio MetaADEDB
Polymyositis MetaADEDB
Polyneuropathy MetaADEDB
Polyuria MetaADEDB
Posture Abnormal MetaADEDB
Premature Rupture Of Membranes MetaADEDB
Primary Hypogonadism MetaADEDB
Progressive Supranuclear Palsy MetaADEDB
Prostatic Calcification MetaADEDB
Prothrombin Level Decreased MetaADEDB
Pruritus Generalised MetaADEDB
Pseudo Lymphoma MetaADEDB
Psychomotor Skills Impaired MetaADEDB
Pulse Abnormal MetaADEDB
Rales MetaADEDB
Refractory Anaemia With An Excess Of Blasts MetaADEDB
Renal Artery Stenosis MetaADEDB
Renal Tubular Disorder MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Gas Exchange Disorder MetaADEDB
Reticulocyte Count Abnormal MetaADEDB
Retinal Bleeding MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retrocollis MetaADEDB
Rhabdomyolysis MetaADEDB
Rhabdomyosarcoma MetaADEDB
Septic Shock MetaADEDB
Serum Ferritin Decreased MetaADEDB
Serum Ferritin Increased MetaADEDB
Shock Haemorrhagic MetaADEDB
Sigmoiditis MetaADEDB
Sinus Bradycardia MetaADEDB
Sinus Rhythm MetaADEDB
Skin Desquamation MetaADEDB
Skin Haemorrhage MetaADEDB
Skin Lesion MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinning Sensation MetaADEDB
Staphylococcal Abscess MetaADEDB
Status Epilepticus MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subcutaneous Emphysema MetaADEDB
Subileus MetaADEDB
Sudden Onset Of Sleep MetaADEDB
Sudden Visual Loss MetaADEDB
Thoracic Vertebral Fracture MetaADEDB
Thrombophlebitis MetaADEDB
Torsade De Pointes MetaADEDB
Total Lung Capacity Decreased MetaADEDB
Toxic Skin Eruption MetaADEDB
Tracheal Diverticulum MetaADEDB
Transaminases Increased MetaADEDB
Transferrin Saturation Increased MetaADEDB
Traumatic Haematoma MetaADEDB
Troponin Increased MetaADEDB
Troponin T MetaADEDB
Tuberculosis Bladder MetaADEDB
Vascular Calcification MetaADEDB
Vascular Graft MetaADEDB
Vascular Skin Disorder MetaADEDB
Vasospasm MetaADEDB
Venous Injury MetaADEDB
Venous Insufficiency MetaADEDB
Venous Occlusion MetaADEDB
Ventricular Dysfunction Left MetaADEDB
Vessel Puncture Site Haematoma MetaADEDB
Vitamin B12 Increased MetaADEDB
Vocal Cord Cyst MetaADEDB
Vocal Cord Inflammation MetaADEDB
Vocal Cord Paralysis MetaADEDB
Wound MetaADEDB
Wrist Fracture MetaADEDB

InAADR: Drug-Protein-ADRs database