InAADR

Drug Information

Drug Name: Eltrombopag (496775-61-2)
PubChem ID: 9846180
SMILES: CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N/N=C/3C=CC=C(C3=O)C4=CC(=CC=C4)C(=O)O)C
InchiKey: TYEXNVNUZXJNBN-YYADALCUSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 442.475
LogP: 3.77946
Ring Count: 3
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 116.55

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort PROTECT
Abdominal Distension PROTECT
Abdominal Pain PROTECT
Abdominal Pain PROTECT
Abdominal Tenderness PROTECT
Acute Myocardial Infarction PROTECT
Alanine Aminotransferase Increased ADReCS
Alopecia ADReCS
Anaemia ADReCS
Anisocytosis PROTECT
Anxiety PROTECT
Apathy PROTECT
Arthralgia PROTECT
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Astigmatism PROTECT
Back Pain ADReCS
Balance Disorder PROTECT
Band Neutrophil Count Increased PROTECT
Blepharitis PROTECT
Blood Albumin Decreased PROTECT
Blood Albumin Increased PROTECT
Blood Alkaline Phosphatase Increased ADReCS
Blood Bilirubin Increased PROTECT
Blood Creatinine Increased PROTECT
Blood Urea Increased PROTECT
Blood Uric Acid Increased PROTECT
Bone Marrow Reticulin Fibrosis PROTECT
Bone Pain PROTECT
Cardiovascular Disorder PROTECT
Cataract ADReCS
Cataract Cortical PROTECT
Cerebral Infarction PROTECT
Chest Pain PROTECT
Chills ADReCS
Cholestasis PROTECT
Cold Sweat PROTECT
Conjunctival Haemorrhage ADReCS
Constipation PROTECT
Contusion PROTECT
Cough ADReCS
Cyanosis PROTECT
Decreased Appetite ADReCS
Deep Vein Thrombosis PROTECT
Depression PROTECT
Dermatosis PROTECT
Diarrhoea ADReCS
Dizziness PROTECT
Dry Eye PROTECT
Dry Mouth ADReCS
Dysaesthesia PROTECT
Dysgeusia PROTECT
Dyspepsia ADReCS
Ear Pain PROTECT
Ecchymosis ADReCS
Electrocardiogram Qt Prolonged PROTECT
Embolism PROTECT
Embolism Arterial ADReCS
Eosinophilia PROTECT
Epistaxis PROTECT
Erythema PROTECT
Eye Pain PROTECT
Faeces Discoloured PROTECT
Fatigue ADReCS
Feeling Hot PROTECT
Feeling Jittery PROTECT
Flatulence PROTECT
Flushing PROTECT
Food Poisoning PROTECT
Frequent Bowel Movements PROTECT
Gingival Bleeding PROTECT
Glossodynia PROTECT
Gout PROTECT
Haematemesis PROTECT
Haematoma PROTECT
Haemoglobin Decreased PROTECT
Haemoglobin Increased PROTECT
Haemolytic Anaemia PROTECT
Haemorrhage ADReCS
Haemorrhoids PROTECT
Headache ADReCS
Hemiparesis PROTECT
Hepatic Function Abnormal PROTECT
Hepatic Lesion PROTECT
Hepatitis PROTECT
Hot Flush PROTECT
Hyperbilirubinaemia ADReCS
Hyperhidrosis PROTECT
Hypersensitivity PROTECT
Hypertension PROTECT
Hypoaesthesia PROTECT
Hypocalcaemia PROTECT
Hypokalaemia PROTECT
Ill-Defined Disorder PROTECT
Increased Appetite PROTECT
Inflammation Of Wound PROTECT
Influenza ADReCS
Influenza Like Illness ADReCS
Insomnia ADReCS
Lacrimation Increased PROTECT
Lenticular Opacities PROTECT
Leukocytosis PROTECT
Leukocyturia PROTECT
Liver Function Test Abnormal ADReCS
Lupus Nephritis PROTECT
Malaise PROTECT
Melanosis PROTECT
Menorrhagia ADReCS
Migraine PROTECT
Migraine With Aura PROTECT
Mood Altered PROTECT
Mouth Haemorrhage PROTECT
Mucosal Inflammation PROTECT
Muscle Spasms PROTECT
Muscular Weakness PROTECT
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Myelocyte Present PROTECT
Myelocytosis PROTECT
Nasal Discomfort PROTECT
Nasopharyngitis PROTECT
Nausea ADReCS
Neuropathy Peripheral PROTECT
Night Sweats PROTECT
No Match PROTECT
Nocturia PROTECT
Non-Cardiac Chest Pain PROTECT
Oedema Peripheral ADReCS
Oral Discomfort PROTECT
Oral Herpes PROTECT
Oropharyngeal Blistering PROTECT
Oropharyngeal Pain ADReCS
Pain PROTECT
Pain In Extremity PROTECT
Palpitations PROTECT
Paraesthesia ADReCS
Peripheral Sensory Neuropathy PROTECT
Petechiae PROTECT
Ph Urine Increased PROTECT
Pharyngitis ADReCS
Pigmentation Disorder PROTECT
Platelet Count Decreased PROTECT
Platelet Count Increased PROTECT
Pneumonia PROTECT
Portal Vein Thrombosis ADReCS
Protein Total Increased PROTECT
Proteinuria PROTECT
Pruritus ADReCS
Pruritus Generalised PROTECT
Pulmonary Embolism PROTECT
Pulmonary Infarction PROTECT
Pyrexia ADReCS
Rash ADReCS
Rectosigmoid Cancer PROTECT
Renal Failure PROTECT
Retinal Haemorrhage PROTECT
Retinal Pigment Epitheliopathy PROTECT
Sensation Of Foreign Body PROTECT
Sensation Of Heaviness PROTECT
Sinus Disorder PROTECT
Sinus Tachycardia PROTECT
Sinusitis PROTECT
Skin Discolouration PROTECT
Skin Exfoliation PROTECT
Sleep Apnoea Syndrome PROTECT
Sleep Disorder PROTECT
Somnolence PROTECT
Speech Disorder PROTECT
Sunburn PROTECT
Swelling Face PROTECT
Tachycardia PROTECT
Tearfulness PROTECT
Thrombocytopenia ADReCS
Thrombophlebitis Superficial PROTECT
Thrombotic Thrombocytopenic Purpura ADReCS
Tonsillitis PROTECT
Toxic Neuropathy PROTECT
Tremor PROTECT
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Urine Protein/Creatinine Ratio Increased PROTECT
Urticaria PROTECT
Vascular Headache PROTECT
Vertigo PROTECT
Vessel Puncture Site Haemorrhage PROTECT
Vision Blurred PROTECT
Visual Acuity Reduced PROTECT
Visual Acuity Tests Abnormal PROTECT
Visual Impairment PROTECT
Vomiting ADReCS
Weight Increased PROTECT
White Blood Cell Count Decreased PROTECT

InAADR: Drug-Protein-ADRs database