InAADR

Drug Information

Drug Name: Vandetanib (443913-73-3)
PubChem ID: 3081361
SMILES: CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
InchiKey: UHTHHESEBZOYNR-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 475.362
LogP: 5.0042
Ring Count: 3
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 59.51

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Bone Marrow Toxicity Grapefruit-medication interactions: forbidden fruit or avoidable consequences?
Grapefruit Juice Torsade De Pointes Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess PROTECT
Abdominal Pain ADReCS
Accommodation Disorder PROTECT
Acne PROTECT
Alanine Aminotransferase Increased ADReCS
Alopecia PROTECT
Amylase Increased PROTECT
Anuria PROTECT
Anxiety PROTECT
Appendicitis PROTECT
Arthralgia ADReCS
Aspartate Aminotransferase Increased PROTECT
Asthenia ADReCS
Balance Disorder PROTECT
Blood Bilirubin Increased ADReCS
Blood Calcium Decreased ADReCS
Blood Calcium Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Glucose Decreased ADReCS
Blood Glucose Increased ADReCS
Blood Magnesium Decreased ADReCS
Blood Magnesium Increased ADReCS
Blood Potassium Decreased ADReCS
Blood Potassium Increased ADReCS
Brain Oedema PROTECT
Bronchitis PROTECT
Cardiac Arrest PROTECT
Cardiac Failure ADReCS
Cardiac Failure Acute PROTECT
Cataract PROTECT
Cellulitis PROTECT
Cerebral Ischaemia PROTECT
Cholelithiasis PROTECT
Chromaturia PROTECT
Clonus PROTECT
Colitis PROTECT
Conjunctivitis PROTECT
Constipation PROTECT
Convulsion PROTECT
Corneal Deposits PROTECT
Corneal Opacity ADReCS
Cough ADReCS
Cystitis PROTECT
Decreased Appetite ADReCS
Dehydration PROTECT
Depression ADReCS
Dermatitis PROTECT
Dermatitis Acneiform ADReCS
Dermatitis Bullous PROTECT
Diarrhoea ADReCS
Diverticulitis PROTECT
Dizziness PROTECT
Dry Eye PROTECT
Dry Mouth PROTECT
Dry Skin ADReCS
Dysaesthesia PROTECT
Dysgeusia PROTECT
Dyspepsia ADReCS
Dysphagia PROTECT
Dysuria PROTECT
Electrocardiogram Qt Prolonged ADReCS
Epistaxis PROTECT
Erythema Multiforme PROTECT
Faecal Incontinence PROTECT
Fatigue ADReCS
Folliculitis PROTECT
Fungal Infection PROTECT
Furuncle PROTECT
Gastritis PROTECT
Gastrointestinal Haemorrhage PROTECT
Glaucoma PROTECT
Haematuria PROTECT
Haemoglobin Decreased ADReCS
Haemoglobin Increased PROTECT
Haemoptysis PROTECT
Haemorrhage ADReCS
Halo Vision PROTECT
Headache ADReCS
Hypercalcaemia PROTECT
Hyperglycaemia PROTECT
Hypertension ADReCS
Hypertensive Crisis PROTECT
Hypocalcaemia ADReCS
Hypokalaemia PROTECT
Hyponatraemia PROTECT
Hypothyroidism PROTECT
Ileus PROTECT
Impaired Healing PROTECT
Influenza PROTECT
Insomnia ADReCS
Interstitial Lung Disease PROTECT
Intestinal Perforation PROTECT
Keratopathy PROTECT
Laryngitis PROTECT
Lethargy PROTECT
Loss Of Consciousness PROTECT
Malnutrition PROTECT
Micturition Urgency PROTECT
Nail Disorder PROTECT
Nasopharyngitis ADReCS
Nausea ADReCS
Nephrolithiasis PROTECT
Neutrophil Count Decreased ADReCS
Oedema PROTECT
Pain PROTECT
Palmar-Plantar Erythrodysaesthesia Syndrome PROTECT
Pancreatitis ADReCS
Paraesthesia PROTECT
Peritonitis PROTECT
Photopsia PROTECT
Photosensitivity Reaction ADReCS
Platelet Count Decreased ADReCS
Pneumonia ADReCS
Pneumonia Aspiration ADReCS
Pneumonitis PROTECT
Pollakiuria PROTECT
Posterior Reversible Encephalopathy Syndrome PROTECT
Proteinuria ADReCS
Pruritus ADReCS
Pyelonephritis PROTECT
Pyrexia ADReCS
Rash ADReCS
Renal Failure PROTECT
Respiratory Arrest ADReCS
Respiratory Failure ADReCS
Sepsis ADReCS
Sinusitis PROTECT
Staphylococcal Infection PROTECT
Stevens-Johnson Syndrome PROTECT
Stomatitis PROTECT
Torsade De Pointes PROTECT
Tremor PROTECT
Upper Respiratory Tract Infection PROTECT
Urinary Tract Infection PROTECT
Ventricular Arrhythmia PROTECT
Vision Blurred ADReCS
Visual Impairment PROTECT
Vomiting ADReCS
Weight Decreased ADReCS
White Blood Cell Count Decreased ADReCS

InAADR: Drug-Protein-ADRs database