| Drug Name: | Sotalol (3930-20-9) |
|---|---|
| PubChem ID: | 5253 |
| SMILES: | CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O |
| InchiKey: | ZBMZVLHSJCTVON-UHFFFAOYSA-N |
| Therapeutic Category: | Adrenergic Agents, Adrenergic Antagonists, Adrenergic beta-Antagonists, Anti-Arrhythmia Agents, Autonomic Agents, Cardiovascular Agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Sympatholytics |
| Molecular Weight (dalton) | : | 272.37 |
| LogP | : | 1.0895 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 3 |
| Total Polar Surface Area | : | 78.43 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Disopyramide ((3737-09-5)) | Asystole | Additive | Not understood. Both disopyramide and the beta blockers can depress the contractility and conductivity of the heart muscle | A case report Sotalol-disopyramide caused asystole |
| Procainamide (51-06-9) | Prolongs The Qt Interval | Additive | Uncertain | Sotalol and type IA drugs in combination prevent recurrence of sustained ventricular tachycardia |
This panel provides drug-protein interaction and their ADRs along with references
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category