InAADR

Drug Information

Drug Name: Madopar (37270-69-2)
PubChem ID:
SMILES: C1=CC(=C(C=C1CC(C(=O)O)N)O)O.C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O
InchiKey: QFLMOYQNYBDXMT-ZCMDIHMWSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 454.436
LogP: -1.704
Ring Count: 2
Hydrogen Bond Acceptor Count: 11
Hydrogen Bond Donor Count: 11
Total Polar Surface Area: 251.85

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Neoplasm MetaADEDB
Abdominal Operation MetaADEDB
Abdominal Symptom MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Vision MetaADEDB
Abuse MetaADEDB
Aching Muscles MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Psychosis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adverse Event MetaADEDB
Affect Lability MetaADEDB
Affective Disorder MetaADEDB
Aggression MetaADEDB
Agraphia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergies MetaADEDB
Alopecia MetaADEDB
Alveolitis MetaADEDB
Amnesia MetaADEDB
Anorexia MetaADEDB
Anosmia MetaADEDB
Aphthous Stomatitis MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Retinopathy MetaADEDB
Aseptic Meningitis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Autonomic Instability MetaADEDB
Bacterial Toxaemia MetaADEDB
Basal Ganglion Degeneration MetaADEDB
Bedridden MetaADEDB
Biliary Fibrosis MetaADEDB
Bladder Distension MetaADEDB
Blepharospasm MetaADEDB
Blindness Transient MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Electrolytes Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Bradycardia MetaADEDB
Breast Discomfort MetaADEDB
Bronchitis MetaADEDB
Bronchopneumonia MetaADEDB
Capillary Disorder MetaADEDB
Cardiac Death MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardiac Perforation MetaADEDB
Cardiac Tamponade MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Disorder MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Infarct MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chill MetaADEDB
Cholangiolitis MetaADEDB
Cholecystectomies MetaADEDB
Cholecystitis MetaADEDB
Cirrhosis MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Bacteraemia MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Colectomy MetaADEDB
Colonic Fistula MetaADEDB
Completed Suicide MetaADEDB
Concomitant Disease Progression MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Convulsions Grand Mal MetaADEDB
Costochondritis MetaADEDB
Cramp MetaADEDB
Cranial Neuropathy MetaADEDB
Cystitis Noninfective MetaADEDB
Deep Brain Stimulation MetaADEDB
Delusion MetaADEDB
Dementia Alzheimer Type MetaADEDB
Depression Suicidal MetaADEDB
Depressive Symptom MetaADEDB
Dermographism MetaADEDB
Disease Of Liver MetaADEDB
Disinhibition MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Drowning MetaADEDB
Drug Chemical Incompatibility MetaADEDB
Duodenal Fistula MetaADEDB
Duodenal Ulcer MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Duodenal Ulcer Perforation MetaADEDB
Dysstasia MetaADEDB
Edema Extremities MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electromechanical Dissociation MetaADEDB
Emphysema MetaADEDB
Enterocolitis MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epstein-Barr Virus Antigen Positive MetaADEDB
Erectile Dysfunction MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Excessive Salivation MetaADEDB
Exophthalmos MetaADEDB
Failure To Anastomose MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Feeding Disorder MetaADEDB
Feeling Cold MetaADEDB
Femur Fracture MetaADEDB
Flight Of Ideas MetaADEDB
Floaters MetaADEDB
Fluid Intake Reduced MetaADEDB
Freezing Phenomenon MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Disorder MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Gastrointestinal Tract Mucosal Discolouration MetaADEDB
Generalised Erythema MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis Proliferative MetaADEDB
Glomerulonephritis Rapidly Progressive MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Hepatitis B MetaADEDB
Hepatitis B Antibody Positive MetaADEDB
Hepatosplenomegaly MetaADEDB
Herpes Ophthalmic MetaADEDB
Herpes Simplex MetaADEDB
Hydrocele Excision MetaADEDB
Hyperparathyroidism Secondary MetaADEDB
Hypersexuality MetaADEDB
Hypogeusia MetaADEDB
Hypokinesia MetaADEDB
Immobile MetaADEDB
Immune Reconstitution Syndrome MetaADEDB
Impulse-Control Disorder MetaADEDB
Incorrect Route Of Drug Administration MetaADEDB
Infantile Spasms MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Initial Insomnia MetaADEDB
Intention Tremor MetaADEDB
Intubation MetaADEDB
Ischaemic Hepatitis MetaADEDB
Knee Operation MetaADEDB
Krabbe Disease MetaADEDB
Laparotomy MetaADEDB
Laryngeal Disorder MetaADEDB
Lip Pain MetaADEDB
Lower Respiratory Tract Infection Viral MetaADEDB
Lung Infiltration MetaADEDB
Lymphocyte Stimulation Test MetaADEDB
Macula Lutea Degeneration MetaADEDB
Malignant Melanoma Stage Ii MetaADEDB
Masked Facies MetaADEDB
Mental Impairment MetaADEDB
Metabolic Acidosis MetaADEDB
Metamorphopsia MetaADEDB
Micturition Urgency MetaADEDB
Monoparesis MetaADEDB
Motor Dysfunction MetaADEDB
Movement Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Muscle Inflammation MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Myocardial Fibrosis MetaADEDB
Near Syncope MetaADEDB
Nerve Conduction Studies Abnormal MetaADEDB
Neumonia MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Nodule MetaADEDB
Optic Disc Edema MetaADEDB
Oral Herpes MetaADEDB
Oral Intake Reduced MetaADEDB
Overdose MetaADEDB
Palsies MetaADEDB
Paraparesis MetaADEDB
Parenteral Nutrition MetaADEDB
Pemphigus MetaADEDB
Penile Oedema MetaADEDB
Peptic Ulcer Perforation MetaADEDB
Performance Status Decreased MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Haemorrhage MetaADEDB
Peritonitis MetaADEDB
Peritonitis Sclerosing MetaADEDB
Phaeochromocytoma MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Po2 Decreased MetaADEDB
Polysubstance Dependence MetaADEDB
Poor Quality Sleep MetaADEDB
Posture Abnormal MetaADEDB
Pre-Existing Condition Improved MetaADEDB
Prostatic Adenoma MetaADEDB
Psychiatric Symptom MetaADEDB
Pupillary Light Reflex Tests Abnormal MetaADEDB
Reflux Esophagitis MetaADEDB
Refusal Of Treatment By Relative MetaADEDB
Regressive Behaviour MetaADEDB
Renal Impairment MetaADEDB
Residual Urine Volume Increased MetaADEDB
Respiratory Disorder MetaADEDB
Resuscitation MetaADEDB
Retinal Pigment Epithelial Tear MetaADEDB
Scab MetaADEDB
Scotoma MetaADEDB
Screaming MetaADEDB
Secondary Hypertension MetaADEDB
Self Injurious Behaviour MetaADEDB
Sensory Loss MetaADEDB
Silicosis MetaADEDB
Sleep Disorder MetaADEDB
Speech Disorder MetaADEDB
Speech Disorder Developmental MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal Deformity MetaADEDB
Spinal Fracture MetaADEDB
Spinal X-Ray MetaADEDB
Spinning Sensation MetaADEDB
Sudden Onset Of Sleep MetaADEDB
Surgery MetaADEDB
Suture Related Complication MetaADEDB
Sympathicotonia MetaADEDB
Synovial Cyst MetaADEDB
Therapy Non-Responder MetaADEDB
Thinking Abnormal MetaADEDB
Thrombophlebitis MetaADEDB
Thyroid Operation MetaADEDB
Tongue Paralysis MetaADEDB
Ulna Fracture MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertigo Positional MetaADEDB
Vestibular Neuronitis MetaADEDB

InAADR: Drug-Protein-ADRs database