InAADR

Drug Information

Drug Name: Rivaroxaban (366789-02-8)
PubChem ID: 9875401
SMILES: C1COCC(=O)N1C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl
InchiKey: KGFYHTZWPPHNLQ-AWEZNQCLSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 435.889
LogP: 2.5199
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 88.18

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Gastrointestinal Bleeding Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain PROTECT
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased ADReCS
Alcoholism MetaADEDB
Amylase Increased PROTECT
Anaemia PROTECT
Anaemia Postoperative PROTECT
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angina Pectoris PROTECT
Aspartate Aminotransferase Increased ADReCS
Asthenia PROTECT
Bile Duct Obstruction MetaADEDB
Bilirubin Conjugated Increased PROTECT
Bleeding Gums MetaADEDB
Blister ADReCS
Blood Alkaline Phosphatase Increased PROTECT
Blood Bilirubin Increased ADReCS
Blood Creatinine Increased PROTECT
Blood Fibrinogen Increased MetaADEDB
Blood Lactate Dehydrogenase Increased PROTECT
Blood Pressure Orthostatic Decreased MetaADEDB
Blood Urea Increased PROTECT
Bloody Discharge MetaADEDB
Bronchiectasis ADReCS
Cerebral Haemorrhage ADReCS
Chest Pain PROTECT
Cholangiolitis MetaADEDB
Cholestasis ADReCS
Chronic Obstructive Airway Disease MetaADEDB
Coagulation Factor X Level Increased MetaADEDB
Compartment Syndrome ADReCS
Conjunctival Haemorrhage PROTECT
Connective Tissue Disorder SIDER
Constipation PROTECT
Contusion PROTECT
Cytolytic Hepatitis ADReCS
Death ADReCS
Dermatitis Allergic PROTECT
Dermatitis Bullous ADReCS
Diarrhoea PROTECT
Dizziness ADReCS
Drug Interaction MetaADEDB
Drug Intolerance MetaADEDB
Dry Mouth PROTECT
Dyspepsia PROTECT
Dyspnoea PROTECT
Dysuria ADReCS
Ecchymosis PROTECT
Effusion MetaADEDB
Epidural Hematoma MetaADEDB
Epistaxis PROTECT
Erosive Gastritis MetaADEDB
Extradural Haematoma ADReCS
Eye Haemorrhage PROTECT
Fatigue PROTECT
Gamma-Glutamyltransferase Increased ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain PROTECT
Gingival Bleeding PROTECT
Haemarthrosis PROTECT
Haematoma ADReCS
Haematuria PROTECT
Haemoglobin ADReCS
Haemoptysis PROTECT
Haemorrhage ADReCS
Haemorrhage Intracranial PROTECT
Haemorrhage Subcutaneous PROTECT
Haemorrhagic Anaemia MetaADEDB
Haemorrhagic Stroke ADReCS
Headache PROTECT
Hemiparesis ADReCS
Hepatic Enzyme MetaADEDB
Hepatic Function Abnormal PROTECT
Hepatitis ADReCS
Hepatobiliary Disease SIDER
Hip Arthroplasty MetaADEDB
Hypercoagulation MetaADEDB
Hypersensitivity ADReCS
Hypokalaemia MetaADEDB
Hypoperfusion PROTECT
Hypotension PROTECT
Hypotension Orthostatic MetaADEDB
Immune System Disorder SIDER
Increased Platelet Count MetaADEDB
Ischaemic Stroke MetaADEDB
Jaundice ADReCS
Joint Effusion MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Lipase Increased PROTECT
Localised Oedema PROTECT
Loss Of Consciousness ADReCS
Malaise PROTECT
Menorrhagia PROTECT
Mental Status Changes MetaADEDB
Muscle Haemorrhage PROTECT
Muscle Spasms ADReCS
Nausea PROTECT
Nervous System Disorder SIDER
Oedema Peripheral PROTECT
Oesophagitis Haemorrhagic MetaADEDB
Osteoarthritis MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Pallor PROTECT
Paraparesis MetaADEDB
Paraplegia MetaADEDB
Pelvic Mass MetaADEDB
Percutaneous Coronary Intervention MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Platelet Count Decreased ADReCS
Platelet Count Increased PROTECT
Post Procedural Discharge MetaADEDB
Post Procedural Haematoma MetaADEDB
Post Procedural Haemorrhage PROTECT
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pruritus Generalised PROTECT
Pulmonary Haemorrhage ADReCS
Pyrexia PROTECT
Rash PROTECT
Rectal Haemorrhage PROTECT
Renal Failure PROTECT
Renal Failure Acute PROTECT
Renal Impairment PROTECT
Retroperitoneal Haemorrhage ADReCS
Secretion Discharge MetaADEDB
Septic Shock MetaADEDB
Shock ADReCS
Skin Haemorrhage PROTECT
Soft Tissue Infection MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spontaneous Haematoma MetaADEDB
Stevens-Johnson Syndrome ADReCS
Subdural Haematoma ADReCS
Sudden Death MetaADEDB
Swelling PROTECT
Syncope ADReCS
Tachycardia PROTECT
Thrombocytosis PROTECT
Tongue Discolouration MetaADEDB
Tooth Discolouration MetaADEDB
Tooth Extraction MetaADEDB
Transaminases Increased PROTECT
Urogenital Haemorrhage PROTECT
Urticaria PROTECT
Vascular Pseudoaneurysm PROTECT
Vomiting PROTECT
Wound Haemorrhage PROTECT
Wound Infection Staphylococcal MetaADEDB
Wound Secretion ADReCS

InAADR: Drug-Protein-ADRs database