InAADR

Drug Information

Drug Name: Avanafil (330784-47-9)
PubChem ID: 9869929
SMILES: COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl
InchiKey: WEAJZXNPAWBCOA-INIZCTEOSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 483.96
LogP: 2.4318
Ring Count: 3
Hydrogen Bond Acceptor Count: 9
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 125.39

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort PROTECT
Abdominal Pain PROTECT
Adenoviral Upper Respiratory Infection ADReCS
Alanine Aminotransferase Increased ADReCS
Angina Pectoris ADReCS
Angina Unstable ADReCS
Arthralgia ADReCS
Asthenia PROTECT
Back Pain ADReCS
Balanitis ADReCS
Blood Bilirubin Increased PROTECT
Blood Creatinine Increased PROTECT
Blood Glucose Increased ADReCS
Blood Pressure Increased PROTECT
Blood Urine Present PROTECT
Body Temperature Increased PROTECT
Bronchitis ADReCS
Cardiac Murmur PROTECT
Chest Pain PROTECT
Constipation ADReCS
Cough ADReCS
Deep Vein Thrombosis ADReCS
Depression ADReCS
Diarrhoea ADReCS
Dizziness ADReCS
Dry Mouth PROTECT
Dyspepsia ADReCS
Dyspnoea Exertional ADReCS
Electrocardiogram Abnormal ADReCS
Epistaxis ADReCS
Fatigue ADReCS
Flank Pain PROTECT
Flushing ADReCS
Gastritis ADReCS
Gastrooesophageal Reflux Disease ADReCS
Gout PROTECT
Haematospermia PROTECT
Haematuria ADReCS
Headache ADReCS
Heart Rate Increased PROTECT
Hepatic Enzyme Increased PROTECT
Hot Flush PROTECT
Hypertension ADReCS
Hypoglycaemia ADReCS
Hypotension PROTECT
Inappropriate Affect PROTECT
Influenza ADReCS
Influenza Like Illness PROTECT
Insomnia ADReCS
Muscle Spasms ADReCS
Muscle Tightness PROTECT
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Nasal Congestion ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Nephrolithiasis ADReCS
Oedema Peripheral PROTECT
Optic Ischaemic Neuropathy PROTECT
Oropharyngeal Pain ADReCS
Pain In Extremity ADReCS
Palpitations ADReCS
Penile Haemorrhage PROTECT
Penis Disorder PROTECT
Periorbital Oedema ADReCS
Pollakiuria ADReCS
Premature Ejaculation PROTECT
Priapism PROTECT
Prostatic Specific Antigen Increased PROTECT
Pruritus ADReCS
Pruritus Genital PROTECT
Psychomotor Hyperactivity PROTECT
Rash ADReCS
Rhinorrhoea PROTECT
Seasonal Allergy PROTECT
Sinus Congestion ADReCS
Sinus Headache PROTECT
Sinusitis ADReCS
Somnolence ADReCS
Spontaneous Penile Erection PROTECT
Stomach Discomfort ADReCS
Sudden Hearing Loss PROTECT
Tachycardia PROTECT
Upper Respiratory Tract Congestion PROTECT
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Vertigo ADReCS
Vision Blurred PROTECT
Vomiting ADReCS
Weight Increased PROTECT
Wheezing ADReCS

InAADR: Drug-Protein-ADRs database