InAADR

Drug Information

Drug Name: Carbidopa (28860-95-9)
PubChem ID: 34359
SMILES: C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN
InchiKey: TZFNLOMSOLWIDK-JTQLQIEISA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 226.232
LogP: -0.0531
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 5
Total Polar Surface Area: 115.81

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Spiramycin (24916-50-5) Reduces The Antiparkinsonian Effects Antagonistic spiramycin markedly reduces the absorption of carbidopa, possibly by forming a non-absorbable complex in the gut or by accelerating its transit through the gut Effect of a macrolide (spiramycin) on the pharmacokinetics of L-dopa and carbidopa in healthy volunteers

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distress ADReCS
Abnormal Dreams ADReCS
Abnormal Gait MetaADEDB
Abnormal Movements MetaADEDB
Abuse MetaADEDB
Accelerated Hypertension MetaADEDB
Aching Joints MetaADEDB
Acute Prerenal Failure MetaADEDB
Adenocarcinoma MetaADEDB
Adenoma MetaADEDB
Agitation ADReCS
Agranulocytosis ADReCS
Alopecia ADReCS
Amentia MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anemia Hemolytic MetaADEDB
Angioedema ADReCS
Anorexia ADReCS
Anxiety ADReCS
Aortic Arteriosclerosis MetaADEDB
Aortic Stenosis MetaADEDB
Aphonia MetaADEDB
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stent Insertion MetaADEDB
Asthenia ADReCS
Ataxia ADReCS
Athetosis MetaADEDB
Atrophy MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Autonomic Instability MetaADEDB
Back Pain ADReCS
Birth Defect MetaADEDB
Bladder Disorder MetaADEDB
Bladder Retention MetaADEDB
Blepharospasm ADReCS
Blood Cholesterol MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Electrolytes Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Glucose Increased ADReCS
Blood Potassium Decreased ADReCS
Blood Sodium Increased MetaADEDB
Bone Disorder MetaADEDB
Bone Spur MetaADEDB
Bradypnoea MetaADEDB
Brain Diseases MetaADEDB
Bronchitis MetaADEDB
Bruise MetaADEDB
Bruxism ADReCS
Bulging MetaADEDB
Burning Sensation Mucosal MetaADEDB
Calcinosis MetaADEDB
Carcinoid Syndrome MetaADEDB
Catalepsy MetaADEDB
Catatonia MetaADEDB
Cerebellar Atrophy MetaADEDB
Cerebral Atrophy MetaADEDB
Cervicalgia MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Chorea ADReCS
Chromaturia ADReCS
Chronic Gastrointestinal Bleeding MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Coccydynia MetaADEDB
Colitis MetaADEDB
Colon Adenoma MetaADEDB
Communication Disorder MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Cor Pulmonale MetaADEDB
Cough ADReCS
Death MetaADEDB
Decreased Interest MetaADEDB
Delusion ADReCS
Dementia ADReCS
Dental Operation MetaADEDB
Depression ADReCS
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diarrhoea ADReCS
Difficulty In Walking MetaADEDB
Dilatation Atrial MetaADEDB
Diplopia ADReCS
Disorientation ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Dopamine Dysregulation Syndrome MetaADEDB
Drug Administration Error MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Ineffective MetaADEDB
Drug Screen Negative MetaADEDB
Drug Toxicity MetaADEDB
Dry Mouth ADReCS
Dry Skin MetaADEDB
Duodenal Ulcer ADReCS
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphonia ADReCS
Dyspnoea ADReCS
Dyspnoea At Rest MetaADEDB
Dysstasia MetaADEDB
Dystonia ADReCS
Early Morning Awakening MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Endodontic Procedure MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Erythema Migrans MetaADEDB
Euphoric Mood ADReCS
Excessive Sleepiness MetaADEDB
Extrapyramidal Disorder ADReCS
Extremity Pain MetaADEDB
Faecaloma MetaADEDB
Fall ADReCS
Fatigue ADReCS
Flatulence ADReCS
Flushing ADReCS
Food Craving MetaADEDB
Foot Deformity MetaADEDB
Gait Disturbance ADReCS
Gastric Ulcer Haemorrhage MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Gingival Pain MetaADEDB
Glossodynia ADReCS
Glucose Urine Present ADReCS
Goiter MetaADEDB
Haematocrit Decreased ADReCS
Haemophilus Sepsis MetaADEDB
Hair Colour Changes MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Hay Fever MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heartburn ADReCS
Hepatic Failure MetaADEDB
Hiccups ADReCS
Hip Arthroplasty MetaADEDB
Hip Fracture MetaADEDB
Horner Syndrome ADReCS
Hot Flush ADReCS
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hypertension ADReCS
Hypoaesthesia ADReCS
Hypokinesia MetaADEDB
Hypotension ADReCS
Ild MetaADEDB
Impaired Driving Ability MetaADEDB
Impaired Healing MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Insomnia ADReCS
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Polyp MetaADEDB
Knee Arthroplasty MetaADEDB
Leg Pain ADReCS
Leukopenia ADReCS
Libido Increased ADReCS
Lung Edema MetaADEDB
Lung Fibrosis MetaADEDB
Malaise ADReCS
Malignant Melanoma ADReCS
Mania MetaADEDB
Maxillofacial Operation MetaADEDB
Mean Cell Volume Increased MetaADEDB
Memory Impairment ADReCS
Meniscus Lesion MetaADEDB
Mental Disorder ADReCS
Micturition Disorder MetaADEDB
Migraine MetaADEDB
Motor Retardation MetaADEDB
Multiple Sclerosis MetaADEDB
Muscle Rigidity MetaADEDB
Muscle Spasms ADReCS
Muscle Twitching ADReCS
Muscle Weakness MetaADEDB
Mydriasis ADReCS
Myocardial Infarction ADReCS
Myoclonus MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Nervousness ADReCS
Neuroleptic Malignant Syndrome ADReCS
Neuropathy Peripheral MetaADEDB
Oculogyric Crisis ADReCS
Oedema ADReCS
On And Off Phenomenon ADReCS
Open Wound MetaADEDB
Oral Disorder MetaADEDB
Oral Fungal Infection MetaADEDB
Oropharyngeal Pain ADReCS
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Ovarian Cancer MetaADEDB
Pain MetaADEDB
Palpitations ADReCS
Panic Disorder MetaADEDB
Paraesthesia ADReCS
Paranoia ADReCS
Parkinson MetaADEDB
Parkinson Disease MetaADEDB
Parkinson Disease Secondary MetaADEDB
Parkinsonian Disorders MetaADEDB
Pemphigoid ADReCS
Periodontal Infection MetaADEDB
Periodontal Operation MetaADEDB
Peripheral Sensory Neuropathy ADReCS
Perirectal Abscess MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phlebitis ADReCS
Phlebothrombosis MetaADEDB
Pleural Effusion MetaADEDB
Pollakiuria ADReCS
Polyuria MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Discomfort MetaADEDB
Post Procedural Infection MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Postoperative Wound Infection MetaADEDB
Priapism ADReCS
Productive Cough MetaADEDB
Pruritus ADReCS
Pulmonary Valve Incompetence MetaADEDB
Rash ADReCS
Red Blood Cell Count Increased MetaADEDB
Red Cell Distribution Width Increased MetaADEDB
Renal Impairment MetaADEDB
Respiratory Rate Increased MetaADEDB
Retrocollis MetaADEDB
Road Traffic Accident MetaADEDB
Saliva Discolouration ADReCS
Salivary Hypersecretion ADReCS
Scleroderma Systemic MetaADEDB
Seizures MetaADEDB
Shoulder Pain ADReCS
Sinus Bradycardia MetaADEDB
Sinus Polyp MetaADEDB
Sinusitis MetaADEDB
Skin Desquamation MetaADEDB
Somnolence ADReCS
Speech Disorder MetaADEDB
Spinal Osteoarthritis MetaADEDB
Staring MetaADEDB
Stem Cell Transplant MetaADEDB
Subileus MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sweat Discolouration ADReCS
Syncope ADReCS
Taste Alteration ADReCS
Therapeutic Product Ineffective MetaADEDB
Therapeutic Response Decreased MetaADEDB
Thrombocytopenia ADReCS
Thyroid Disease MetaADEDB
Thyroiditis Chronic MetaADEDB
Tooth Extraction MetaADEDB
Tooth Impacted MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Trismus ADReCS
Upper Respiratory Tract Infection ADReCS
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Infection ADReCS
Urosepsis MetaADEDB
Urticaria ADReCS
Uterine Bleeding MetaADEDB
Vision Blurred ADReCS
Vomiting ADReCS
Vulvovaginal Mycotic Infection MetaADEDB
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database